Acute Pyelonephritis


4.7 out of 5 (309 Reviews)



Pharmacology Credits


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Start Date

1 Sep 2023

Last Review Date

28 Feb 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes

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Activity Description

Acute pyelonephritis is a bacterial infection causing inflammation of the kidneys. Pyelonephritis is generally a complication of an ascending urinary tract infection that spreads from the bladder to the kidneys. Certain populations, such as pediatric patients, renal transplant patients, and pregnant patients, warrant special attention. Symptoms usually include fever, flank pain, nausea, vomiting, burning with urination, increased urinary frequency, and urgency. It is important to differentiate acute pyelonephritis, a medical condition treated primarily with antibiotics, from pyonephrosis (obstructive pyelonephritis), a clinically similar condition that requires urgent surgical drainage of an obstructed, infected renal pelvis. The microbiology of pyelonephritis can be complex, and antibiotic resistance is common. The role of imaging is discussed, and suggested empiric antibiotics are identified. This activity outlines the clinical presentation, diagnosis, and management of acute pyelonephritis and highlights the role of the interprofessional team in caring for patients with the condition.

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the clinical features and risk factors associated with acute pyelonephritis.

  • Describe expected signs and symptoms in a patient with pyelonephritis.

  • Select appropriate imaging modalities for diagnosing acute pyelonephritis and monitoring treatment response.

  • Collaborate with interprofessional teams, including urologists, radiologists, and infectious disease specialists, to optimize patient care.

  • Outline the pharmacologic therapy as it applies to Acute Pyelonephritis


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Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.


Nurse Practitioners: StatPearls designates this activity for 1.50 ANCC contact hour(s), which includes 0.5 hour(s) of pharmacology. NPs should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

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This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.




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include images

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This was under Pediatric infectious disease but most of the cases/ material was about adults

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Thanks much

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Lota of new information

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Too adult oriented.

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