Genetics and Obesity


4.5 out of 5 (39 Reviews)



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Start Date

1 Sep 2023

Last Review Date

1 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes

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Activity Description

Obesity is closely linked to genetics and environmental factors. The newest studies in the field of epigenetics further our understanding of the effect of the environment on genetics. This article describes the genetic causes of obesity, including syndromic, monogenic, and polygenic causes, and cites specific examples of epigenetic modifications associated with obesity. This activity reviews the evaluation and treatment of genetically predisposed obesity and highlights the role of the interprofessional team in evaluating and treating patients with this condition.

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, nurse practitioners, and social workers.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Describe the need for genome and epigenome-wide association studies to understand better how obesity can be inherited.
  • Identify the important genes associated with syndromic and non-syndromic obesity.
  • Describe the crucial times in human life when epigenetic modifications can occur.
  • Explain the importance of a detailed history, physical examination, and genetic tests that can be used to diagnose genetically and epigenetically inherited causes of obesity.


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Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

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Social Workers: StatPearls, LLC designates this continuing education activity for 1.50 ASWB ACE credit(s) for social workers. Social Workers should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

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This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.




Bryan R. on 11/2/2021

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Manish Kumar S. on 10/16/2022

Raymond A. on 11/30/2022

This was one of the best reviews I have seen in STT PEARLS. I was led to believe that FTO was the. Most commmon cause of monogenic obesity in adults. Where does it fit compared with MCR4 in adults? Could the author send me a response. Do I need to send the question some other way?

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