Pediatric-Nephrology

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Acute Cystitis

Urinary tract infections are the most common bacterial infection in women, and result in roughly eight million emergency ...
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Acute Pyelonephritis

Acute pyelonephritis is a bacterial infection causing inflammation of the kidneys. Pyelonephritis occurs as a complicati ...
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Hematuria

Hematuria is the presence of blood in the urine. Hematuria can be gross or microscopic; gross hematuria is visible blood ...
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Pediatric Fluid Management

Dehydration occurs commonly in children and many times requires resuscitation. Fluid resuscitation is essential in the m ...
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Hepatitis B Vaccine

The hepatitis B vaccine is a medication used in the prevention of hepatitis B infection, which can lead to chronic liver ...
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Renal Transplantation Rejection

Various factors merit consideration to match the donor kidney with the recipient, as the donor kidney act as an alloanti ...
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Pediatric-Nephrology Activities

Title	Description	Hours	Questions
Acrodynia	Acrodynia is a rare disorder caused due to chronic mercury poisoning or idiosyncrasy to mercury. It is a Greek term that means 'painful extremities.' ... Read the Article	0.75	5	Activity MD/PA Activity DO
Acute Cystitis	Urinary tract infections are the most common bacterial infection in women, and result in roughly eight million emergency department or clinic visits a ... Read the Article	1	10	Activity MD/PA Activity DO
Acute Kidney Injury	Acute kidney injury, previously known as acute renal failure, denotes a sudden and often reversible reduction in the kidney function, as measured by ... Read the Article	1.5	20	Activity MD/PA Activity DO
Acute Pyelonephritis	Acute pyelonephritis is a bacterial infection causing inflammation of the kidneys. Pyelonephritis occurs as a complication of an ascending urinary tra ... Read the Article	1.25	15	Activity MD/PA Activity DO
Acute Renal Tubular Necrosis	The most common intrinsic cause of acute kidney injury is acute tubular necrosis. Acute tubular necrosis is most common in hospitalized patients and c ... Read the Article	1	7	Activity MD/PA Activity DO
Acyclovir	Acyclovir is a medication used in the management and treatment of infections caused by the herpes simplex virus (HSV). It is FDA approved to treat gen ... Read the Article	1	8	Activity MD/PA Activity DO
Alport Syndrome	Alport syndrome is a genetic condition characterized by kidney disease, loss of hearing, and eye abnormalities. It takes place due to an abnormality o ... Read the Article	0.75	6	Activity MD/PA Activity DO
Analgesic Nephropathy	Analgesic nephropathy is chronic tubulointerstitial nephritis caused by chronic use of analgesics such as acetaminophen, aspirin, and NSAIDs as the pr ... Read the Article	0.75	5	Activity MD/PA Activity DO
Aniridia	Aniridia is defined as a partial or complete absence of the iris. It may be associated with various systemic disorders and multiple ocular morbidities ... Read the Article	1	6	Activity MD/PA Activity DO
Azathioprine	Azathioprine (AZA) is a medication used in the management and treatment of active rheumatoid arthritis (RA) and the prevention of kidney transplant r ... Read the Article	0.75	5	Activity MD/PA Activity DO
Bartter Syndrome	Bartter syndrome is an autosomal recessive disorder of salt reabsorption resulting in extracellular fluid volume depletion with low/normal blood press ... Read the Article	0.75	5	Activity MD/PA Activity DO
Beckwith Wiedemann Syndrome	Beckwith-Wiedemann Syndrome is the most common overgrowth syndrome. It is a genetic imprinting disorder, and it can present as a wide and varied clini ... Read the Article	1	6	Activity MD/PA Activity DO
Berger Disease	Berger disease is a common cause of primary glomerulonephritis and it involves the deposition of IgA in the glomerular mesangium. It is a cause of pro ... Read the Article	1	8	Activity MD/PA Activity DO
Cadmium Toxicity	Cadmium is a heavy metal that causes direct harm to humans in several forms. It is regularly found with other heavy metals such as zinc, copper, and ... Read the Article	0.75	6	Activity MD/PA Activity DO
Carnitine Deficiency	Carnitine deficiency is a condition characterized by low carnitine levels in the body. Carnitine deficiency could be primary (due to defect in carniti ... Read the Article	0.75	5	Activity MD/PA Activity DO
Cerebral Salt Wasting Syndrome	Cerebral salt wasting (CSW) is a potential cause of hyponatremia in the setting of disease of the central nervous system (CNS). Cerebral salt wasting ... Read the Article	1	7	Activity MD/PA Activity DO
Chronic Kidney Transplant Rejection	Kidney transplantation is currently the definitive treatment for patients with end-stage kidney disease (ESKD). Compared to dialysis, kidney transpla ... Read the Article	0.75	5	Activity MD/PA Activity DO
Cinacalcet	Cinacalcet is a medication used in the management and treatment of secondary hyperparathyroidism (on dialysis population), primary hyperparathyroidism ... Read the Article	0.75	5	Activity MD/PA Activity DO
Cloacal Malformations	Cloacal malformations are rare congenital anomalies characterized by a confluence of the gastrointestinal, genital, and urologic systems which exits t ... Read the Article	0.75	4	Activity MD/PA Activity DO
Congenital Adrenal Hyperplasia	Congenital adrenal hyperplasia (CAH) is an autosomal recessive disease emerging from mutations of genes for enzymes that lead to the production of glu ... Read the Article	1	10	Activity MD/PA Activity DO
Corticosteroid Adverse Effects	Corticosteroids are hormone mediators produced by the cortex of adrenal glands that further categorize into glucocorticoids, mineralocorticoids, and a ... Read the Article	1	6	Activity MD/PA Activity DO
Cystic Kidney Disease	Cystic kidney diseases are multisystemic disorders that can develop due to genetic or non-genetic causes in children and adults. These can be a seriou ... Read the Article	1	11	Activity MD/PA Activity DO
Cystinuria	Cystine stones are due to an inherited defect in the transport of the amino acid cystine leading to excessive excretion in the kidney causing cystinur ... Read the Article	0.75	5	Activity MD/PA Activity DO
Cytomegalovirus	Cytomegalovirus (CMV) is a wide-spread virus, with manifestations ranging from asymptomatic to severe end-organ dysfunction in immunocompromised patie ... Read the Article	1	12	Activity MD/PA Activity DO
Deferoxamine	Deferoxamine is a medication used in Iron and aluminum toxicity. It is in the chelator class of drugs. This activity reviews the indications, mechanis ... Read the Article	1	7	Activity MD/PA Activity DO
Diabetes Insipidus	Diabetes insipidus (DI) is a disease process that results in either decreased release of or response to antidiuretic hormone (ADH, also known as vasop ... Read the Article	1.25	15	Activity MD/PA Activity DO
Enterohemorrhagic Escherichia Coli	Enterohemorrhagic Escherichia coli (EHEC) is a bacterial infection resulting in bloody dysentery and an increased risk of hemolytic uremic syndrome (H ... Read the Article	1	7	Activity MD/PA Activity DO
Erythropoietin	Erythropoietin (EPO) is a glycoprotein hormone, naturally produced by the peritubular cells of the kidney, that stimulates red blood cell production. ... Read the Article	1	7	Activity MD/PA Activity DO
Essential Hypertension	The current definition of hypertension (HTN) is systolic blood pressure (SBP) values of 130mmHg or more and/or diastolic blood pressure (DBP) more tha ... Read the Article	1.25	16	Activity MD/PA Activity DO
Ethylene Glycol Toxicity	Ethylene glycol (C2H6O2) is a toxic alcohol that is found in various household and industrial agents. Ethylene glycol exposure can be extremely danger ... Read the Article	1	7	Activity MD/PA Activity DO
Fabry Disease	Fabry disease is a multi-systemic, X-linked recessive lysosomal storage disease caused by decreased activity of alpha-galactosidase A and results in l ... Read the Article	1	9	Activity MD/PA Activity DO
Fanconi Syndrome	Fanconi syndrome, not to be confused with Fanconi anemia, is a defect of the proximal tubule that prevents the absorption of electrolytes and other su ... Read the Article	0.75	6	Activity MD/PA Activity DO
Fluid Management	Hospitalized patients often have conditions that impair their ability to regulate their hydration status. Improper fluid management leads to significa ... Read the Article	1	10	Activity MD/PA Activity DO
Gadolinium Magnetic Resonance Imaging	Contrast agents are pharmaceuticals that increase the information content of diagnostic images. They serve to improve the sensitivity and specificity ... Read the Article	1	8	Activity MD/PA Activity DO
Gitelman Syndrome	Gitelman syndrome is a salt-losing tubulopathy caused by mutation of genes encoding sodium chloride (NCCT) and magnesium transporters in the thiazide- ... Read the Article	0.75	6	Activity MD/PA Activity DO
Glomerulonephritis	The term "glomerulonephritis" encompasses a subset of renal diseases characterized by immune-mediated damage to the basement membrane, mesangium, or t ... Read the Article	1.25	16	Activity MD/PA Activity DO
Goodpasture Syndrome	Goodpasture syndrome, also referred to as anti-glomerular basement membrane (anti-GBM) disease, is an autoimmune disease that affects both the kidneys ... Read the Article	1.25	13	Activity MD/PA Activity DO
Hartnup Disease	Hartnup disease is an autosomal recessive disorder resulting in impaired functioning of transport protein in intestines and kidneys. This results in w ... Read the Article	1	9	Activity MD/PA Activity DO
Hematuria	Hematuria is the presence of blood in the urine. Hematuria can be gross or microscopic; gross hematuria is visible blood in urine whereas microscopic ... Read the Article	1	9	Activity MD/PA Activity DO
Hemolytic Uremic Syndrome	Hemolytic uremic syndrome (HUS) is thrombotic microangiopathy characterized by the presence of the triad of symptoms: thrombocytopenia, acute renal im ... Read the Article	1	9	Activity MD/PA Activity DO
Henoch Schonlein Purpura	Henoch-Schonlein purpura is an IgA-mediated immune vasculitis involving the small vessels of the joints, kidneys, gastrointestinal (GI) tract, skin, a ... Read the Article	0.75	6	Activity MD/PA Activity DO
Hepatitis B Vaccine	The hepatitis B vaccine is a medication used in the prevention of hepatitis B infection, which can lead to chronic liver failure and hepatocellular ca ... Read the Article	1.25	13	Activity MD/PA Activity DO
Hepatitis C	Hepatitis C virus (HCV) is a major public health problem affecting 185 million people worldwide. The percentage of people who are seropositive for ant ... Read the Article	1.5	24	Activity MD/PA Activity DO
Horseshoe Kidney	Horseshoe kidneys are the most common fusion defect of the kidneys occurring in approximately 1:500 individuals. They are characterized by abnormaliti ... Read the Article	1	8	Activity MD/PA Activity DO
Hydronephrosis And Hydroureter	Hydronephrosis and hydroureter result from obstruction of urine flow in the urinary system at the renal pelvis and ureter level, respectively. This is ... Read the Article	0.75	5	Activity MD/PA Activity DO
Hypercalciuria	Hypercalciuria is generally considered to be the most common identifiable metabolic risk factor for calcium nephrolithiasis. It also contributes to os ... Read the Article	1	6	Activity MD/PA Activity DO
Hyperchloremic Acidosis	Hyperchloremic metabolic acidosis is a pathological state that results from bicarbonate loss, rather than acid production or retention. Bicarbonate lo ... Read the Article	0.75	6	Activity MD/PA Activity DO
Hyperkalemia	Hyperkalemia is defined as a serum or plasma potassium level above the upper limits of normal, usually greater than 5.0 mEq/L to 5.5 mEq/L. While mild ... Read the Article	1.25	14	Activity MD/PA Activity DO
Hyperphosphatemia	This article summarises the basics of Hyperphosphatemia, including its pathophysiology, evaluation, and management. Though this condition is seen more ... Read the Article	1	6	Activity MD/PA Activity DO
Hypokalemia	One of the most common electrolyte disturbances seen in clinical practice is hypokalemia. Hypokalemia is more prevalent than hyperkalemia, and most ca ... Read the Article	1	12	Activity MD/PA Activity DO
Hypomagnesemia	Magnesium is an important electrolyte. It is a key part of many reactions that occur in the human body, affecting cellular function, nerve conduction, ... Read the Article	0.75	3	Activity MD/PA Activity DO
Hypomelanosis of Ito	Hypomelanosis of Ito (HI), or pigmentary mosaicism, was previously named incontinentia pigmenti achromians. The disease is currently named hypomelanos ... Read the Article	0.75	4	Activity MD/PA Activity DO
Hypophosphatemia	Given its widespread role in nearly every molecular, cellular function, aberrations in serum phosphate levels can be highly impactful. Hypophosphatemi ... Read the Article	0.75	5	Activity MD/PA Activity DO
Hypospadias	Hypospadias is an anatomical congenital malformation of the male external genitalia. It is characterized by abnormal development of the urethral fold ... Read the Article	1	7	Activity MD/PA Activity DO
Idiopathic Pulmonary Hemorrhage	Idiopathic pulmonary hemorrhage is a rare condition caused by bleeding into the lower respiratory tract, usually the alveoli. Its classical presentati ... Read the Article	0.75	6	Activity MD/PA Activity DO
Ifosfamide	Ifosfamide is a cytotoxic medication used in the management and treatment of various cancers such as lymphomas, sarcomas, and lung cancers. It is in t ... Read the Article	0.75	5	Activity MD/PA Activity DO
IgA Nephropathy	IgA nephropathy is a common forms of glomerulonephritis caused by the deposition of IgA type immunoglobulins in the glomerular basement membrane. Immu ... Read the Article	1	8	Activity MD/PA Activity DO
Intramedullary Spinal Cord Tumors	Tumors in the spine comprise about 15 percent of all central nervous system tumors. They usually are benign and cause symptoms primarily via compressi ... Read the Article	0.75	5	Activity MD/PA Activity DO
Isopropanol Toxicity	Isopropanol, or isopropyl alcohol, is a clear, colorless liquid that emits an odor that resembles acetone. It is a commercially available product main ... Read the Article	0.75	5	Activity MD/PA Activity DO
Kidney Trauma	Renal trauma can result in injury to the parenchyma or the renal vasculature which can cause bleeding or injury to the collecting system with possible ... Read the Article	1	10	Activity MD/PA Activity DO
Left Renal Vein Obstruction	Left renal vein obstruction, also known as Nutcracker phenomenon (NCP), occurs due to the external compression of the left renal vein (LRV) in between ... Read the Article	0.75	5	Activity MD/PA Activity DO
Leptospirosis	Leptospirosis, also called Weil disease, is the most common zoonotic infection in the world. Leptospirosis is caused by an infection with the spiroche ... Read the Article	1	11	Activity MD/PA Activity DO
Medullary Sponge Kidney	Medullary sponge kidney is a benign congenital abnormality that was first described in 1939. Anatomically it is characterized by cystic dilatation of ... Read the Article	0.75	4	Activity MD/PA Activity DO
Methanol Toxicity	Methanol (CH3OH) is a toxic alcohol that is found in various household and industrial agents. Methanol exposure can be extremely dangerous, with signi ... Read the Article	1.5	23	Activity MD/PA Activity DO
Minimal Change Disease	Minimal change disease (MCD), is one of the most common causes of idiopathic nephrotic syndrome in children. In the past, MCD was given the labels "ni ... Read the Article	1	10	Activity MD/PA Activity DO
Nail Patella Syndrome	Nail patella syndrome (NPS) is a rare multisystemic disease with a classic clinical tetrad of fingernail dysplasia, hypoplasia or absence of the patel ... Read the Article	1	7	Activity MD/PA Activity DO
Nephrotic Syndrome	Nephrotic syndrome (NS) is a clinical syndrome defined by massive proteinuria (greater than 40 mg/m2 per hour) responsible for hypoalbuminemia (less t ... Read the Article	1	12	Activity MD/PA Activity DO
Nocturnal Enuresis	Enuresis refers to the involuntary loss of urine during sleep that occurs at least twice a week in children older than 5 years of age (or the developm ... Read the Article	1	7	Activity MD/PA Activity DO
Normal Saline	Fluid therapy is a critical component of the clinical management of patients. It consists of colloid therapy as well as crystalloid therapy. The most ... Read the Article	0.75	6	Activity MD/PA Activity DO
Nutcracker Syndrome	Nutcracker syndrome is a venous compression syndrome involving the left renal vein. It is an uncommon, although possibly underdiagnosed, condition tha ... Read the Article	0.75	5	Activity MD/PA Activity DO
Orthostatic Proteinuria	Orthostatic proteinuria, also known as postural proteinuria, is a condition where an abnormally large amount of protein is excreted in the urine when ... Read the Article	0.75	5	Activity MD/PA Activity DO
Paroxysmal Nocturnal Hemoglobinuria	Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease that presents clinically with a variety of nonspecific symptoms. It causes complications m ... Read the Article	1	8	Activity MD/PA Activity DO
Patent Urachus	Patent urachus refers to a spectrum of umbilical disorders that result from the failure of involution of normal embryologic tissues that connect the d ... Read the Article	0.75	5	Activity MD/PA Activity DO
Pediatric Craniopharyngioma	Pediatric craniopharyngioma could be considered one of the most complex neurosurgical pathologies in the pediatric population. The tumor's proximity t ... Read the Article	0.75	5	Activity MD/PA Activity DO
Pediatric Fluid Management	Dehydration occurs commonly in children and many times requires resuscitation. Fluid resuscitation is essential in the management of critically ill ch ... Read the Article	1	11	Activity MD/PA Activity DO
Pelvic Kidney	The term pelvic kidney encompasses a range of anatomical abnormalities that occur when the kidney fails to rise from the pelvis in its metanephros sta ... Read the Article	0.75	4	Activity MD/PA Activity DO
Peripheral Vascular Bypass	Peripheral vascular bypass (PVB) refers to surgical revision of blood flow to restore perfusion distal to an occluded or otherwise disrupted arterial ... Read the Article	0.75	4	Activity MD/PA Activity DO
Polycystic Kidney Disease Of Childhood	There are two inherited varieties of polycystic kidney disease (PKD): autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive pol ... Read the Article	1	7	Activity MD/PA Activity DO
Posterior Urethral Valve	This article contains a synopsis of the anatomy, embryology, and classification of posterior urethral valves with a brief discussion of the theories a ... Read the Article	1	6	Activity MD/PA Activity DO
Postobstructive Diuresis	Urinary retention is a relatively common urological problem encountered in both inpatient and outpatient settings. It should be high on the differenti ... Read the Article	0.75	6	Activity MD/PA Activity DO
Postoperative Fever	Postoperative fever is defined as a temperature higher than 38 C (or greater than 100.4 F) on two consecutive postoperative days or higher than 39 C ( ... Read the Article	0.75	5	Activity MD/PA Activity DO
Poststreptococcal Glomerulonephritis	Poststreptococcal glomerulonephritis (PSGN) results from a bacterial infection that causes rapid deterioration of the kidney function due to an inflam ... Read the Article	1	12	Activity MD/PA Activity DO
Potter Syndrome	Potter syndrome is a fatal congenital disorder characterized by the changes in physical appearances of neonate due to oligohydramnios caused by renal ... Read the Article	1	6	Activity MD/PA Activity DO
Primary Hyperaldosteronism	Primary hyperaldosteronism (PA) is an underdiagnosed cause of hypertension. The classic presentation of PA includes hypertension and hypokalemia. Howe ... Read the Article	1	10	Activity MD/PA Activity DO
Prune Belly Syndrome	Prune belly syndrome is a rare congenitally acquired disorder primarily characterized by the clinical triad of deficient abdominal musculature, crypto ... Read the Article	1	8	Activity MD/PA Activity DO
Pseudohypoparathyroidism	Pseudohypoparathyroidism is a rare disorder where patients are resistant to parathyroid hormone. Parathyroid hormone resistance leads to hypocalcemia ... Read the Article	0.75	6	Activity MD/PA Activity DO
Pulseless Electrical Activity	Pulseless electrical activity (PEA), also known as electromechanical dissociation, is a clinical condition characterized by unresponsiveness and impal ... Read the Article	1	8	Activity MD/PA Activity DO
Reflux Nephropathy	Reflux nephropathy (RN) often presents in early adulthood with various clinical manifestations of chronic kidney disease. Reflux nephropathy was previ ... Read the Article	0.75	4	Activity MD/PA Activity DO
Renal Calculi	Renal calculi are a common cause of blood in the urine (hematuria) and pain in the abdomen, flank, or groin. They occur in one in 11 people at some ti ... Read the Article	1	6	Activity MD/PA Activity DO
Renal Cyst	Renal cysts are the most common lesion of the kidney and are seen in approximately 40 percent of patients that undergo imaging studies involving the a ... Read the Article	0.75	5	Activity MD/PA Activity DO
Renal Transplantation Rejection	Various factors merit consideration to match the donor kidney with the recipient, as the donor kidney act as an alloantigen. In general, when transpla ... Read the Article	0.75	4	Activity MD/PA Activity DO
Renal Tubular Acidosis	Kidneys play a pivotal role in maintaining the acid-base balance of body along with lungs, and they do so by reabsorbing filtered bicarbonate and remo ... Read the Article	1.25	12	Activity MD/PA Activity DO
Renal Vein Thrombosis	Renal vein thrombosis (RVT), the presence of thrombus in the major renal veins or its tributaries, is a rare clinical entity. It can present acutely o ... Read the Article	0.75	5	Activity MD/PA Activity DO
Serum Sickness	Serum sickness is a rare but important cause of fever, arthritis, and rash in both children and adults. This activity reviews the differences between ... Read the Article	0.75	5	Activity MD/PA Activity DO
Sickle Cell Trait	Sickle cell trait (SCT) is a benign condition in which the affected individual has only one abnormal hemoglobin beta gene allele. This is in contrast ... Read the Article	0.75	6	Activity MD/PA Activity DO
Spina Bifida	Spina Bifida is a generalized term for the neurologic condition resulting from the failure of neural tube closure of varying degrees during fetal deve ... Read the Article	1.25	14	Activity MD/PA Activity DO
Syndrome of Inappropriate Antidiuretic Hormone Secretion	Syndrome of inappropriate antidiuretic hormone ADH release (SIADH) is a condition defined by the unsuppressed release of antidiuretic hormone (ADH) fr ... Read the Article	1	11	Activity MD/PA Activity DO
Tuberous Sclerosis	Tuberous sclerosis complex (TSC) is a genetic disorder that affects multiple systems. It is inherited in an autosomal dominant fashion and is characte ... Read the Article	2	34	Activity MD/PA Activity DO
Ulcerative Colitis	Ulcerative colitis is an idiopathic inflammatory condition of the colon which results in diffuse friability and superficial erosions on the colonic wa ... Read the Article	1.5	23	Activity MD/PA Activity DO
Ureterolithiasis	Ureterolithiasis is a painful condition that affects millions of Americans each year. To avoid the high morbidity and mortality associated with this c ... Read the Article	0.75	5	Activity MD/PA Activity DO
Ureteropelvic Junction Obstruction	Ureteropelvic junction obstruction (UPJO) is one of the most common causes of hydronephrosis in children. If it is left untreated, it might cause loss ... Read the Article	0.75	5	Activity MD/PA Activity DO
Vesicoureteral Reflux	Retrograde urine flow from the bladder to the upper urinary tract is known as vesicoureteric reflux. This article illustrates the anatomy and pathophy ... Read the Article	1	6	Activity MD/PA Activity DO
Vinca Alkaloid Toxicity	Vinca alkaloids, which belong to a class of cell cycle phase M specific anti-tubulin agents are one of the first plant alkaloids to be developed for u ... Read the Article	1	6	Activity MD/PA Activity DO
Vitamin D	Vitamin D is labeled as the "sunshine vitamin," as it is produced in the skin on sun exposure. Vitamin D is required to maintain serum calcium concent ... Read the Article	1	7	Activity MD/PA Activity DO
Von Hippel Lindau Syndrome	Von Hippel-Lindau (VHL) syndrome is an autosomal dominant disease affecting several organ systems. The disease is characterized by the growth of cysts ... Read the Article	1	7	Activity MD/PA Activity DO
Von Willebrand Disease	Von Willebrand disease is a bleeding disorder caused by the qualitative or quantitative deficiency of the pro-von Willebrand factor. Affected people m ... Read the Article	0.75	5	Activity MD/PA Activity DO
Waterhouse-Friderichsen Syndrome	Waterhouse Friderichsen syndrome is a rare but life-threatening disorder associated with bilateral adrenal hemorrhage. In many cases, it is caused by ... Read the Article	0.75	5	Activity MD/PA Activity DO
Wilms Tumor	Wilms tumor, or nephroblastoma, is the most common pediatric renal cancer, the most common pediatric abdominal cancer, and the fourth most common pedi ... Read the Article	1.25	15	Activity MD/PA Activity DO

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Pediatric-Nephrology