Preexposure Prophylaxis for HIV Prevention


4.7 out of 5 (15 Reviews)



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Start Date

1 Sep 2023

Last Review Date

28 Jan 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes

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Activity Description

Preexposure prophylaxis (PrEP) is highly effective in preventing human immunodeficiency virus (HIV) and is an essential tool for decreasing HIV transmission in high-risk populations. However, PrEP is underutilized as a preventive measure due to multiple barriers faced by individuals with a high risk of acquiring HIV.

This activity provides clinicians with vital knowledge to tackle the ongoing global challenge of HIV prevention. Exploring the rationale, treatment options, and adherence strategies for PrEP empowers participants with the insights needed to address the unique needs of diverse populations and deliver optimal care to individuals at significant risk of HIV infection. Clinicians learn strategies for effective care coordination and communication among team members, ensuring an approach beyond medication prescription. Empowering clinicians involves integrating quality improvement and public health perspectives, emphasizing the significance of local epidemiology and the social contexts influencing HIV transmission. This approach enables the development of tailored services, programs, and policies that effectively address the population's needs.

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, nurse practitioners, and dentists.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify individuals at substantial risk for human immunodeficiency virus infection who may benefit from preexposure prophylaxis based on local epidemiology, demographic factors, and behavioral considerations.

  • Apply a comprehensive understanding of preexposure prophylaxis regimens, including daily oral medications and injectable options, to recommend appropriate therapy considering patient preferences, lifestyle, and potential adverse effects. 

  • Assess ongoing adherence to preexposure prophylaxis, utilizing nonjudgmental communication strategies to identify any challenges patients face in adhering to the prescribed regimen and engaging in collaborative decision-making to address barriers. 

  • Collaborate with an interprofessional healthcare team, including physicians, advanced practitioners, pharmacists, nurses, community care workers, and public health professionals, to create a holistic approach to preexposure prophylaxis delivery tailored to diverse patient populations' psychosocial and support needs. 


StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.


Physicians and Physician Associates: StatPearls, LLC designates this enduring material for a maximum of 1.50 AMA PRA Category 1 Credit(s)TM. Physicians and PAs should only claim credit commensurate with the extent of their participation in the activity.

American Board of Internal Medicine: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.50 MOC points and patient safety MOC credit in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

American Board of Pediatrics: Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn up to 1.50 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit learner completion information to ACCME for the purpose of granting ABP MOC credit.

Royal College of Physicians and Surgeons of Canada: Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact


This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.




Hassan A. on 9/15/2021

Joseph T. on 3/30/2022

Leon C. on 10/10/2022

Jasmine J. on 3/25/2023

Christina M. on 4/10/2023

Needs to be updated to include information about Cabotegravir (Apretude) and Descovy for PrEP etc.

Anandit M. on 6/19/2023

Very excellent activity, well-written and discussed. Very important information for clinicians broken down in concrete, understandable terms.

Bernadette M. on 6/24/2023

Abhishek K. on 7/5/2023

Hertzel s. on 7/13/2023

IKE O. on 8/6/2023

Madhu U. on 8/7/2023

Stephen P. on 9/5/2023

Kristy H. on 9/8/2023

Everett M. on 11/5/2023

Christine G. on 12/13/2023

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