Merkel Cell Carcinoma of the Skin

Overview

4.7 out of 5 (1531 Reviews)

Credits

1.00

Post-Assessment Questions

10

Start Date

1 Sep 2023

Last Review Date

1 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


Unlimited Physician CME

Stay up to date on the latest medical knowledge with 6789 CME activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 8067.5 hours of CME.

Learn About Lifetime CME

Single Activity

Take this single activity

$49 1 activity

6 Month Unlimited Physician CME

Access to all the Unlimited Physician CME activities in all specialties.

$329 per half year per user

1 Year Unlimited Physician CME

Access to all the Unlimited Physician CME activities in all specialties.

$499 per 1 year per user
 
Need Help?  If you have a system or content concerns, please contact support@statpearls.com

Activity Description

Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine tumor of the skin with increasing incidence. It most frequently presents on the head and neck region of elderly, white males. Specific risk factors include ultraviolet (UV) exposure, advancing age, and immunosuppression, and its development is associated with Merkel cell polyomavirus (MCPyV) infection. Skin biopsy is diagnostic, and sentinel lymph node evaluation should be performed in all patients who are diagnosed with MCC, as the disease typically has a rapidly progressive course. Treatment consists of wide local excision with or without adjuvant radiotherapy for the local disease. New therapies for metastatic MCC have shown promise and include immune-based therapies. This activity illustrates the evaluation and treatment of the patients presenting with Merkel cell carcinoma and reviews the role of the interprofessional team in improving care for patients with this condition.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Review the most common risk factors associated with development of Merkel cell carcinoma.

  • Identify the indications for sentinel lymph node biopsy or fine need aspiration in the work-up of Merkel cell carcinoma.

  • Explain the common physical exam findings in patients with Merkel cell carcinoma.

  • Explain the importance of collaboration and communication amongst the interprofessional team to ensure rapid detection, complete work-up, and initiation of appropriate therapy for patients with Merkel cell carcinoma.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Physicians and Physician Associates: StatPearls, LLC designates this enduring material for a maximum of 1.00 AMA PRA Category 1 Credit(s)TM. Physicians and PAs should only claim credit commensurate with the extent of their participation in the activity.

American Board of Internal Medicine: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.00 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

American Board of Otolaryngology–Head and Neck Surgery: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn their required annual part II self-assessment credit in the American Board of Otolaryngology–Head and Neck Surgery’s Continuing Certification program (formerly known as MOC). It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of recognizing participation.

American Board of Pathology: Successful completion of this Continuing Certification activity, which includes participation in the evaluation component, enables the participant to earn up to 1.00 Lifelong Learning (CME) credits in the American Board of Pathology’s Continuing Certification Program.

American Board of Surgery: Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn credit toward the CME and Self-Assessment requirement(s) of the American Board of Surgery’s Continuous Certification program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABS credit.

Royal College of Physicians and Surgeons of Canada: Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Katarzyna B. on 12/12/2020

David R. on 1/24/2023

Jude D. on 4/4/2023

Georgia L. on 6/20/2023

Sijo T. on 9/4/2023

rachel l. on 9/4/2023

Manula R. on 9/4/2023

Ian W. on 9/4/2023

Alban M. on 9/4/2023

James M. on 9/4/2023

Kelly P. on 9/4/2023

Ashley M. on 9/4/2023

Lokeswari B. on 9/4/2023

mark g. on 9/4/2023

Gloria J. on 9/4/2023

Excellent topic!

Antonio R. on 9/5/2023

Andy N. on 9/5/2023

Ali S. on 9/5/2023

Heather H. on 9/5/2023

Stephanie M. on 9/5/2023

Daniya Z. on 9/6/2023

kerry k. on 9/6/2023

Amelia L. on 9/6/2023

Sara R. on 9/6/2023

Agnes P. on 9/6/2023

Alison S. on 9/6/2023

Marybeth C. on 9/6/2023

Karen H. on 9/6/2023

Birgit A. on 9/7/2023

Holly K. on 9/7/2023

Kimberly M. on 9/7/2023

Sallie B. on 9/7/2023

Steven S. on 9/7/2023

Emily M. on 9/7/2023

Jennifer R. on 9/7/2023

Blake H. on 9/7/2023

Patrick B. on 9/7/2023

Andre D. on 11/6/2023

Holly H. on 8/14/2024

Cristina A. on 9/7/2023

Brandi H. on 9/7/2023

Leah B. on 9/8/2023

pertinent study topics. like the teaching summaries.

Ethan P. on 9/7/2023

Keyla D. on 9/7/2023

Christopher D. on 9/7/2023

Harlan H. on 9/7/2023

Current celebrities dealing with health issues are great ways to learn - and earn CMEs (ie comedian Bernie Mac and Sarcoid, politician John McCain and glioblastoma). Keep up the good work.

SALVADOR B. on 9/7/2023

RICHARD P. on 9/7/2023

Gale W. on 9/7/2023

Floyd P. on 9/7/2023

Cindy D. on 9/7/2023

Pamela K. on 9/7/2023

Robbin C. on 9/7/2023

Heather B. on 9/7/2023

Abdo K. on 9/8/2023

Neil J. on 9/8/2023

Jenna H. on 9/8/2023

Juana G. on 9/8/2023

Suzanne B. on 9/8/2023

Deb S. on 9/8/2023

Lisa H. on 9/8/2023

Dennis B. on 9/8/2023

Kendall M. on 9/9/2023

Kristin M. on 9/8/2023

Terrie R. on 9/8/2023

Emily S. on 9/8/2023

Paige S. on 9/8/2023

Ernest S. on 9/8/2023

Angela B. on 9/8/2023

Diana D. on 9/8/2023

Lorna P. on 9/8/2023

Ravi P. on 9/8/2023

Erin C. on 9/8/2023

Karen B. on 9/8/2023

Lori G. on 9/8/2023

Rainel L. on 9/8/2023

Thank you. And God bless Jimmy Buffett.

Randal S. on 9/8/2023

Anna S. on 9/8/2023

Nancy M. on 9/8/2023

Tanyel M. on 9/8/2023

James H. on 9/8/2023

William S. on 12/30/2023

Leigh M. on 9/8/2023

Karin C. on 9/8/2023

Marvin C. on 9/8/2023

Megan S. on 9/8/2023

Cheryl J. on 9/9/2023

Paula T. on 9/8/2023

Diane M. on 9/8/2023

Michelle M. on 9/8/2023

Holly C. on 9/30/2024

Robert S. on 9/8/2023

Christa K. on 9/8/2023

Michelle G. on 9/8/2023

Elizabeth S. on 9/9/2023

michael l. on 9/11/2023

HARRY B. on 9/9/2023

Desiree J. on 9/9/2023

DONNA A. on 9/10/2023

Morgan M. on 9/10/2023

Virginia M. on 9/10/2023

Loretta T. on 9/10/2023

Lydia K. on 9/10/2023

Cynthia P. on 9/10/2023

Alyssa H. on 9/11/2023

Richard D. on 9/11/2023

Lori W. on 9/11/2023

Danna R. on 9/11/2023

Eileen W. on 9/11/2023

Brittany M. on 9/11/2023

Heather J. on 9/11/2023

Haresh K. on 9/11/2023

Jennifer O. on 9/11/2023

Jennifer K. on 9/11/2023

Mary H. on 9/12/2023

Dan D. on 9/11/2023

Christina M. on 9/13/2023

Kedaari A. on 9/11/2023

James L. on 9/12/2023

Susan M. on 9/12/2023

Christina M. on 9/12/2023

Sarah R. on 9/12/2023

Jennifer P. on 9/12/2023

ROBERT M. on 9/12/2023

Rhonda C. on 9/12/2023

Julia D. on 9/13/2023

miles l. on 9/13/2023

M M. on 9/13/2023

Stephani C. on 9/13/2023

Molly N. on 9/13/2023

lori d. on 9/13/2023

Robert C. on 9/13/2023

Howard R. on 9/13/2023

elie k. on 9/13/2023

Nirupama P. on 9/13/2023

Zbigniew C. on 9/13/2023

Rebelee J. on 9/13/2023

Christopher B. on 9/14/2023

Linda C. on 9/14/2023

Leslie L. on 9/14/2023

pictures of lesion would be helpful

Gayle N. on 9/14/2023

Lisa G. on 9/14/2023

Bwayne M. on 9/14/2023

Rena R. on 9/14/2023

Mark C. on 9/14/2023

Serge D. on 9/14/2023

Sailu G. on 9/14/2023

Paul D. on 9/14/2023

Information was very informative.

LaShanda S. on 9/14/2023

Katia P. on 9/15/2023

Amanda P. on 9/15/2023

Edelweiss v. on 9/15/2023

Mark G. on 9/15/2023

Piyush D. on 9/15/2023

Byron L. on 9/15/2023

PRABHA P. on 9/15/2023

Jody P. on 9/17/2023

Marie L. on 9/15/2023

Marilyn K. on 9/15/2023

Anthony H. on 9/15/2023

Kelli W. on 9/15/2023

ALLISON A. on 9/15/2023

Kumar Y. on 9/15/2023

CHAULA P. on 9/18/2023

Thank you

Jennifer G. on 9/15/2023

RAJEEV S. on 9/16/2023

Zachary P. on 11/30/2023

Karen V. on 9/16/2023

Alison G. on 9/16/2023

Danielle W. on 9/16/2023

Kimberly K. on 9/16/2023

Katherine L. on 9/16/2023

Edward D. on 9/16/2023

Josh S. on 9/16/2023

Meril M. on 9/17/2023

Heidi O. on 9/17/2023

S s. on 9/17/2023

Paula F. on 9/17/2023

Essam M. on 9/17/2023

Jonathan Z. on 9/18/2023

Stephanie K. on 9/18/2023

Appreciated the detail in epidemiology, diagnosis and therapy for this disease.

Mitchell G. on 9/18/2023

shereen a. on 9/18/2023

Yvonne C. on 9/18/2023

Jonathan P. on 9/18/2023

Rodney T. on 9/18/2023

Talisa B. on 9/18/2023

Paul R. on 9/18/2023

Aaron B. on 9/19/2023

Carol S. on 9/19/2023

Sarah S. on 9/19/2023

Peter L. on 9/19/2023

howard b. on 9/19/2023

Heather S. on 9/19/2023

Donna M. on 9/19/2023

on 9/19/2023

Carol B. on 9/19/2023

Donna A. on 9/25/2023

Brandy S. on 9/19/2023

Phoebe H. on 9/19/2023

Sharon S. on 9/20/2023

Kimberly G. on 9/19/2023

Honeyia I. on 9/20/2023

Todd M. on 9/20/2023

Samantha L. on 9/20/2023

Allison E. on 9/20/2023

Dara d. on 9/30/2023

mary m. on 9/20/2023

Valneo B. on 9/21/2023

Carlyn R. on 9/21/2023

Jessica K. on 9/21/2023

Rosemarie D. on 9/21/2023

Jerrin L. on 9/21/2023

Shaojung H. on 9/21/2023

Tracey S. on 9/21/2023

Alan Y. on 9/21/2023

Carolyn G. on 9/21/2023

ALAN V. on 9/23/2023

Althea B. on 9/22/2023

Thelma H. on 9/22/2023

Shah Abdul L. on 9/22/2023

Mia B. on 9/22/2023

Huy D. on 9/22/2023

Leslie V. on 9/22/2023

Sheila D. on 9/22/2023

None

Rodney Q. on 9/22/2023

Justin S. on 9/22/2023

Anna-Lise D. on 9/22/2023

Darryn M. on 9/22/2023

Sara G. on 9/23/2023

Shoba m. on 9/23/2023

Amanda V. on 9/23/2023

Melissa B. on 9/24/2023

Lisa O. on 9/24/2023

Samuel O. on 9/24/2023

gerard b. on 9/24/2023

Xiao C. on 9/25/2023

none

Marie-Reine B. on 9/25/2023

Mehek B. on 9/25/2023

Arpi P. on 9/25/2023

Christopher H. on 9/25/2023

Thank you for these well-researched teaching summaries of timely topics

DEBBIE M. on 9/25/2023

Kimberly C. on 9/25/2023

Lindsay G. on 9/25/2023

Alex C. on 9/25/2023

xiao l. on 9/25/2023

Kathleen H. on 9/26/2023

Misti D. on 9/26/2023

aref h. on 9/26/2023

Natalie L. on 9/26/2023

Lora G. on 9/26/2023

Deyette W. on 9/26/2023

Tawakalitu A. on 9/26/2023

Kerry R. on 9/26/2023

Jaclyn V. on 9/26/2023

Lynn H. on 9/26/2023

none

Melissa B. on 9/26/2023

krishnan s. on 9/26/2023

John C. on 9/26/2023

Sarah H. on 9/26/2023

Elizabeth N. on 9/26/2023

Merdith C. on 9/26/2023

Ann K. on 9/27/2023

Amanda a. on 9/27/2023

Emily B. on 9/27/2023

JENNIFER H. on 9/27/2023

Niji S. on 9/27/2023

quanmei d. on 9/27/2023

Dominique B. on 9/27/2023

Yashoda B. on 9/27/2023

Brian C. on 9/28/2023

SULTAN Q. on 9/28/2023

Disha P. on 9/29/2023

Arnold W. on 9/28/2023

Caleb C. on 9/28/2023

Very helpful materials with relevant questions

Pauline T. on 9/29/2023

Monica D. on 9/29/2023

Patricia N. on 9/29/2023

Danielle D. on 9/29/2023

Tahmina H. on 9/29/2023

Davenna M. on 9/29/2023

Jason J. on 10/12/2023

Vivian A. on 10/4/2023

Paula t. on 9/29/2023

excellent exercise!!

Mark S. on 9/30/2023

Suzana S. on 9/30/2023

Lindie J. on 9/30/2023

Genevieve M. on 9/30/2023

Whitney A. on 9/30/2023

Teressa C. on 9/30/2023

Sharon H. on 10/1/2023

Stephanie S. on 10/1/2023

Kaylee R. on 10/1/2023

Stephanie C. on 10/1/2023

Peter K. on 10/3/2023

jennifer m. on 10/1/2023

Madison G. on 10/1/2023

Whitney K. on 10/1/2023

Tiffany G. on 10/1/2023

Katie H. on 10/1/2023

OGLEH N. on 10/1/2023

Alexis H. on 10/2/2023

Susan F. on 10/2/2023

Gwen U. on 10/2/2023

Alejandro B. on 10/2/2023

Sara K. on 10/2/2023

Megan J. on 10/2/2023

raoul m. on 10/2/2023

victoria b. on 10/2/2023

David F. on 10/2/2023

Mark P. on 10/2/2023

Laila E. on 10/3/2023

Clinical cases broaden the essential key points of the article.

Dung N. on 10/10/2023

Aldona S. on 10/3/2023

Leonardo G. on 10/3/2023

Daniel C. on 10/3/2023

Julie J. on 10/3/2023

Kathleen W. on 10/3/2023

TERESA K. on 10/3/2023

Kathy V. on 10/3/2023

Crystal C. on 10/3/2023

Brett C. on 10/3/2023

Gursimar S. on 10/3/2023

John M. on 10/3/2023

Laura C. on 10/3/2023

Carol W. on 10/3/2023

Young Mee C. on 10/3/2023

Barbara D. on 10/3/2023

Jennifer M. on 10/3/2023

Misty w. on 10/4/2023

Rachel B. on 10/4/2023

Preman S. on 10/4/2023

Dr O. on 10/4/2023

Shiny J. on 10/4/2023

Excellent program

Devonne B. on 10/4/2023

Daniel L. on 10/4/2023

Ronald B. on 10/5/2023

Paul T. on 10/5/2023

Emily J. on 10/5/2023

Maura J. on 10/5/2023

Joseph C. on 10/5/2023

Timothy R. on 10/5/2023

Carmen K. on 10/5/2023

Olatokunbo A. on 10/6/2023

Shyann W. on 10/6/2023

Katherine P. on 10/6/2023

Jaspreet K. on 10/6/2023

Cindy A. on 10/6/2023

Arlenny S. on 10/6/2023

Margaret S. on 10/6/2023

Deb H. on 10/6/2023

Kristin S. on 10/6/2023

kenneth h. on 10/6/2023

Tao L. on 10/6/2023

Arnold G. on 10/7/2023

Lisa K. on 10/7/2023

Loice S. on 10/7/2023

Randi P. on 10/8/2023

Susan D. on 10/8/2023

Pallavi K. on 10/8/2023

Kaci S. on 10/8/2023

nellie b. on 10/8/2023

Mary Ellen C. on 10/8/2023

Tareq Y. on 10/8/2023

Luz Stella M. on 10/17/2023

Marissa D. on 10/9/2023

Maria C. on 10/9/2023

Ala M. on 10/9/2023

Deanna S. on 10/9/2023

Cheryl P. on 10/9/2023

Felicia J. on 10/9/2023

Lori M. on 10/9/2023

Khader M. on 10/9/2023

Imiyah W. on 10/9/2023

rajab i. on 10/9/2023

Emilly B. on 10/13/2023

Haley O. on 10/10/2023

Darlene C. on 10/10/2023

Katherine H. on 10/10/2023

Lauren B. on 10/10/2023

Corey E. on 10/10/2023

Amy H. on 10/16/2023

Sidney H. on 10/11/2023

Jennie M. on 10/11/2023

Jeffrey L. on 10/11/2023

Athina S. on 10/11/2023

Emmanuel N. on 10/12/2023

Marie E. on 10/11/2023

Cathy M. on 10/12/2023

HEDVIG K. on 10/11/2023

Lauren G. on 10/11/2023

donna c. on 10/12/2023

Destoni J. on 10/12/2023

John S. on 10/12/2023

Ananya D. on 10/12/2023

Omar T. on 10/12/2023

Donna G. on 10/12/2023

Emily B. on 10/12/2023

Sonya M. on 10/12/2023

Shafqat S. on 10/12/2023

Simone C. on 10/12/2023

Good job!

Timothy M. on 10/12/2023

Mark B. on 10/13/2023

wasim s. on 10/13/2023

Cynthia c. on 10/13/2023

Magis M. on 10/13/2023

Dawn M. on 10/13/2023

ravinder w. on 10/13/2023

Please report my activity/credit to ABIM for MOC

Mariana R. on 10/13/2023

Jennifer P. on 10/13/2023

Rose M. on 10/14/2023

William M. on 10/14/2023