Adrenoleukodystrophy

Overview

4.4 out of 5 (67 Reviews)

Credits

1.50

Post Assessment Questions

9

Start Date

1 Sep 2023

Last Review Date

4 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes


 
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Activity Description

Adrenoleukodystrophy is a peroxisomal disorder resulting from abnormal metabolism of the very-long-chain fatty acids (VLCFA). It is classified into different subtypes based on the mode of inheritance, clinical presentation, age of onset, and organs involved. The prognosis is poor, and the majority of affected patients will develop neurological disabilities and death. This activity reviews the pathophysiology, evaluation, management, and prognosis of the different adrenoleukodystrophy types and highlights the new updates about the diagnosis and treatment options that are available or under investigation for this condition.

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Describe the pathophysiology of the different types of adrenoleukodystrophy.
  • Outline the clinical presentation of the different types of adrenoleukodystrophy disorders.
  • Review the diagnostic workup for adrenoleukodystrophy.
  • Review the treatment options and prognosis of adrenoleukodystrophy.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Physicians and Physician Associates: StatPearls, LLC designates this enduring material for a maximum of 1.50 AMA PRA Category 1 Credit(s)TM. Physicians and PAs should only claim credit commensurate with the extent of their participation in the activity.

American Board of Internal Medicine: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.50 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

American Board of Pathology: Successful completion of this Continuing Certification activity, which includes participation in the evaluation component, enables the participant to earn up to 1.50 Lifelong Learning (CME) credits in the American Board of Pathology’s Continuing Certification Program.

American Board of Pediatrics: Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn up to 1.50 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit learner completion information to ACCME for the purpose of granting ABP MOC credit.

Royal College of Physicians and Surgeons of Canada: Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Donna M. on 5/24/2021

Gibi G. on 10/17/2021

Dr Haresh D. on 11/5/2021

Mark K. on 11/5/2021

Bibhu Prasad N. on 11/28/2021

Dr. N Bhargav R. on 12/2/2021

Dr.Mallikarjun K. on 12/15/2021

Subhranshu Sekhar K. on 3/11/2022

Surabhi C. on 3/23/2022

Dr.Ayodhyaprasad S. on 4/20/2022

Dr.Mallikarjun K. on 5/1/2022

Manish Kumar S. on 5/17/2022

saurabh t. on 5/21/2022

Bhabesh D. on 6/4/2022

Prabhat K. on 6/14/2022

K.Navanitha R. on 6/29/2022

Samir P. on 6/21/2022

Sonika M. on 7/19/2022

Poornima V. on 7/26/2022

Dr Jagveer S. on 8/8/2022

dolly k. on 8/26/2022

SYED M. on 12/3/2022

Murchana K. on 9/17/2022

Trinadh Naidu C. on 10/15/2022

Sweta S. on 10/30/2022

MARINA K. on 11/5/2022

Dr Amrita K. on 11/26/2022

Jacqueline B. on 12/29/2022

Arelly J. on 1/21/2023

Parthiban B. on 2/3/2023

Parash Pratim B. on 2/20/2023

Poornima V. on 2/28/2023

Arun K. on 4/6/2023

Bhavika Y. on 3/8/2023

Przemyslaw L. on 3/11/2023

none

Ritu R. on 4/2/2023

Akshaya K. on 4/10/2023

Ajay P. on 4/14/2023

Adithya nikhileshwar B. on 4/22/2023

Alexander W. on 4/25/2023

Nida A. on 5/5/2023

Gautam P. on 5/10/2023

Sushma B. on 5/20/2023

Kurni R. on 5/29/2023

Nisha C. on 6/9/2023

Crystal c. on 6/9/2023

Anuradha S. on 6/11/2023

Hansika S. on 8/4/2023

Nivetha V. on 9/16/2023

Larry M. on 9/30/2023

mode of inheritance of PEX genes not priovided

louis v. on 10/25/2023

Jayakaviyah R. on 11/3/2023

Beji J. on 11/4/2023

Ashok V. on 11/5/2023

Devyani S. on 11/9/2023

Malani K. on 12/3/2023

Melissa B. on 12/11/2023

Dr. Neha K. on 12/21/2023

Brian M. on 12/20/2023

There is a sentence that does not make sense in one of the first parts of describing the natural history for a patient with X-linked ALD. The sentence has a duplicated phrase that reappears at the end of the sentence and does not make sense in that order in the sentence. For example, the phrase says something like "death, followed by" other complications of the illness.

Mary S. on 12/29/2023

Dr. Neha K. on 1/2/2024

Bhabesh D. on 1/10/2024

Karl K. on 1/13/2024

Noybe R. on 1/14/2024

Glenn S. on 2/1/2024

Anuradha S. on 2/3/2024

john d. on 2/23/2024

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