Amphetamine Toxicity


4.6 out of 5 (55 Reviews)



Post Assessment Questions


Expiration Date

28 Feb 2026

Last Reviewed

1 Mar 2023

Estimated Time To Finish

90 Minutes

Need Help?  If you have a system or content concerns, please contact

Activity Description

Amphetamine abuse is widespread, and overdose is associated with significant and negative impacts on the cardiovascular and neurological systems. Patients may present with psychiatric and medical problems that may include seizures, arrhythmias, and psychosis. These patients need aggressive supportive care in a quiet environment with close monitoring. This activity examines when amphetamine toxicity should be considered on differential diagnosis and how to properly evaluate for it. This activity highlights the role of the interprofessional team in caring for affected patients.

Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the epidemiology of amphetamine toxicity.
  • Describe history and physical exam findings that may be present in patients with amphetamine toxicity.
  • Outline the treatment and management options available for amphetamine toxicity,
  • Explain the need for a well-integrated, interprofessional team approach to improve care for patients with amphetamine toxicity.


StatPearls requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. None of the planners of this educational activity have any relevant financial relationships to disclose.

COMMERCIAL SUPPORT: This activity has received NO commercial support.

Continuing Education Accreditation Information

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Quillen College of Medicine, East Tennessee State University, and StatPearls, LLC. The Quillen College of Medicine, East Tennessee State University is accredited by the ACCME to provide continuing medical education for physicians.

Quillen College of Medicine, East Tennessee State University designates this activity for a maximum of 1.50 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This activity is reported to the following Maintenance of Certification (MOC) boards:
American Board of Anesthesiology
  • Ambulatory/Outpatient
  • Neuro Anesthesia
American Board of Internal Medicine
  • Adolescent Medicine
  • Cardiovascular Disease
  • Critical Care Medicine
  • Internal Medicine
  • Nephrology
  • Sleep Medicine
  • Sports Medicine
  • Gastroenterology
American Board of Pathology
  • Cardiovascular
  • Chemical Pathology
  • GI (incl. Liver, Pancreas, Bilary)
  • Neuropathology (incl. Neuromuscular)
American Board of Pediatrics
  • Pediatric Cardiology
  • Pediatric Gastroenterology
  • Pediatric Nephrology
  • Pediatric Neurology

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content in the activity.
  4. Choose the best answer to each activity test question. To receive credit, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment.
  6. Obtain a certificate.

For information on the applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.


Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on StatPearls specifically disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Cancellation Policy: Cancellations must be received in writing and a money-back guarantee is provided if not completely satisfied.

  • StatPearlsand and Quillen College of Medicine, East Tennessee State University reserve the right to cancel any course due to unforeseen circumstances. StatPearls andQuillen College of Medicine, East Tennessee State University will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Medium or Media Used:

  • Computer Requirements: Internet Access
  • E-mail Address

Equal Opportunity

  • StatPearls andQuillen College of Medicine, East Tennessee State University are Equal Opportunity/Affirmative Action/Equal Access Institutions. 


Media Usage Rights

The contributors and editors of StatPearls have attested that all associated media (images and video) have been legally cleared for use with this activity.  All copyrights are reserved.


    Deborah Z. on 2/24/2021

    JULIE J. on 4/9/2021

    Studying for CARN. Taking StatPearls quizzes to prepare. Find that many questions are diagnostic and treatment based and wonder if those are actually more suited for CARN-AP which is for a Nurse Practitioner.

    Marjorie S. on 4/10/2021

    Laura C. on 5/31/2021

    edwina w. on 8/29/2021

    Derek K. on 9/19/2021

    Hartmut U. on 9/22/2021

    John L. on 9/30/2021

    Rebecca B. on 10/11/2021

    Therese M. on 10/22/2021

    David G. on 10/29/2021

    Jennifer S. on 11/8/2021

    Jessica S. on 11/14/2021

    Thomas C. on 11/16/2021

    Ehsan Q. on 1/3/2022

    Melinda N. on 1/18/2022

    Kevin C. on 1/20/2022

    Samantha B. on 2/7/2022

    Justin M. on 2/12/2022

    elizabeth d. on 2/22/2022

    Cynthia F. on 2/27/2022

    Candace B. on 3/2/2022

    Cori B. on 3/2/2022

    Jane O. on 3/4/2022

    SANTHA A. on 3/5/2022

    Ira on 3/23/2022

    Charlene N. on 4/7/2022

    Jeannine D. on 4/23/2022

    Lisa E. on 5/2/2022

    Christopher T. on 5/21/2022

    John P. on 5/25/2022

    Jessica K. on 6/5/2022

    Lauren I. on 6/19/2022

    Brian T. on 7/20/2022

    Charles T. on 7/28/2022

    Amy l. on 9/4/2022

    Michael S. on 9/7/2022

    Monica K. on 10/2/2022

    Eli N. on 9/26/2022

    MARIUS T. on 10/6/2022

    Tracy E. on 10/28/2022

    good info

    Kenneth R. on 11/12/2022

    Scott K. on 11/15/2022

    Tammy L. on 11/27/2022

    Andrea C. on 12/4/2022

    Brittany N. on 12/15/2022

    Thomas J. on 1/12/2023

    merrill h. on 12/27/2022

    Ginger B. on 1/5/2023

    Marilyn F. on 1/17/2023

    Florence Y. on 1/20/2023

    Latoya R. on 1/23/2023

    Myriame N. on 1/25/2023

    Emmanuel E. on 3/5/2023

    Jeffrey H. on 3/7/2023

    Unlimited Physician CME

    Stay up to date on the latest medical knowledge with 6674 CME activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 7931 hours of CME.

    Learn About Lifetime CME

    Single Activity

    Take this single activity

    $39 1 activity

    6 Month Unlimited Physician CME

    Access to all the Unlimited Physician CME activities in all specialties.

    $289 per half year per user

    1 Year Unlimited Physician CME

    Access to all the Unlimited Physician CME activities in all specialties.

    $399 per 1 year per user