Overview

4.7 out of 5 (15 Reviews)

Credits

1.00

Post Assessment Questions

6

Start Date

1 Jan 2021

Last Review Date

1 Feb 2024

Expiration Date

31 Dec 2023

Estimated Time To Finish

60 Minutes


 
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Activity Description

Zileuton, a 5-lipoxygenase inhibitor, is a primary intervention for the prophylaxis and treatment of chronic asthma in patients aged 12 and older. Although zileuton is frequently administered in conjunction with inhaled corticosteroids for chronic asthma, it is not effective for managing acute asthma attacks. 

Zileuton is also used off-label in patients with aspirin-induced asthma. The application of the drug extends to aspirin-induced asthma, with research supporting its efficacy in chronic obstructive pulmonary disease and dermatological conditions such as acne, pruritic manifestations in Sjögren-Larsson syndrome, and atopic dermatitis. This activity delves into the complexities of clinical toxicity, drug interactions, pharmacokinetics, and the importance of vigilant monitoring while administering zileuton to patients. This activity equips the interprofessional healthcare team with the necessary skills to manage diverse clinical scenarios and improve patient care in the context of respiratory and dermatological conditions using zileuton effectively.


Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify appropriate candidates for zileuton therapy based on their age (12 and older) and a diagnosis of chronic asthma.

  • Implement vigilant monitoring protocols for patients receiving zileuton, considering clinical toxicity, drug interactions, and pharmacokinetics.

  • Select optimal combinations of zileuton with other medications for patients with chronic myeloid leukemia or aspirin-exacerbated respiratory disease.

  • Collaborate with the interprofessional healthcare team to coordinate comprehensive patient care, integrating zileuton appropriately into treatment plans.

Disclosures

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Continuing Education Accreditation Information

 

 

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.00 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

 

 
 

Reviews

Harry A. on 10/17/2021

Rebecca K. on 4/18/2022

Meredith K. on 4/20/2022

Abhinav P. on 12/9/2022

Richard D. on 12/21/2022

Rebecca K. on 2/9/2023

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