A Review Of Hereditary Colorectal Cancers


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Expiration Date

31 Dec 2023

Last Reviewed

1 Jan 2021

Estimated Time To Finish

60 Minutes

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Activity Description

Colorectal cancer is the fourth leading cause of death in the world. Many cases of colorectal cancer are associated with lifestyle factors such as obesity and lack of exercise, inadequate consumption of fruits, vegetables, fiber, fish, vitamin C, dairy products, and vitamin D, and excessive consumption of alcohol and red meat. The inherited colorectal cancer syndromes are a series of diseases in which specific mutations predispose to colorectal cancer. They are more aggressive and have a worse prognosis since they generally form additional tumors and do not always respond to chemotherapy. This activity will review the most common genetic syndromes associated with colorectal cancer and outline the medical and surgical treatment approach according to current evidence. This activity will highlight the role of the interprofessional team in recognizing and treating colorectal cancer.

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Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Explain how to counsel a patient about lifestyle to decrease their risk of developing sporadic colorectal cancer.
  • Identify the types of hereditary colorectal cancer toward which the Modified Betheseda Criteria and the Amsterdam II Criteria are geared.
  • Describe a patient presentation consistent with hereditary polyposis colorectal cancer.
  • Outline approaches that the interprofessional care team can use to assist in recognizing, preventing, and managing colorectal cancer.

Author(s) / Contributors Disclosure of Conflicts of Interest

Each author, editor, faculty and planning committee member have completed a disclosure form indicating that neither they nor their spouse/partner has a financial interest/arrangement or affiliation that could be perceived as a real or apparent conflict of interest related to the content of this activity.

COMMERCIAL SUPPORT: This activity has received NO commercial support.

Continuing Education Accreditation Information

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Quillen College of Medicine, East Tennessee State University, and StatPearls, LLC. The Quillen College of Medicine, East Tennessee State University is accredited by the ACCME to provide continuing medical education for physicians.

Quillen College of Medicine, East Tennessee State University designates this activity for a maximum of 1.00 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This activity is reported to the following Maintenance of Certification (MOC) boards:
American Board of Anesthesiology
  • General Operative Anesthesia
American Board of Internal Medicine
  • Endocrinology, Diabetes, and Metabolism
  • Geriatric Medicine
  • Hospital Medicine
  • Internal Medicine
  • Medical Oncology
American Board of Pathology
  • Clinical Pathology
  • GI (incl. Liver, Pancreas, Bilary)
  • Surgical Pathology
American Board of Pediatrics
  • Pediatric Hematology-Oncology
American Board of Surgery
  • Complex General Surgical Oncology
  • General Surgery

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  • StatPearls and ETSU reserve the right to cancel any course due to unforeseen circumstances. StatPearls and ETSU will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and ETSU are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives, and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation survey. 
  7. Obtain a certificate.

StatPearls and ETSU adhere to ACCME Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and ETSU that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved, and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

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Media Usage Rights

The contributors and editors of StatPearls have attested that all associated media (images and video) have been legally cleared for use with this activity.  All copyrights are reserved.

  • Name: 'Metastasis_sites_for_common_cancers.svg.png' Attribution: Contributed by Wikimedia Commons,"Medical gallery of Mikael Häggström 2014" (Public Domain)
  • Name: 'Colorectal Carcinoma Screening Guidelines .jpg' Attribution: Colorectal Carcinoma Screening Gu


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Great site! will surely replace Wikipedia soon Provide more articles for general medicine please

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