IgA Pemphigus

Overview

4 out of 5 (1 Reviews)

Credits

1.00

Pharmacology Credits

0.5

Post Assessment Questions

6

Start Date

1 Sep 2023

Last Review Date

1 May 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


 
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Activity Description

IgA pemphigus, an uncommon autoimmune blistering skin disorder, manifests as painful, itchy blisters that fill with neutrophils and evolve into pustules. This condition encompasses 2 clinically similar subtypes: subcorneal pustular dermatosis and intraepidermal neutrophilic dermatosis. Both subtypes exhibit distinct immunologic mechanisms targeting keratinocyte cell surface components. Diagnosis and subtype determination rely on histopathology and immunofluorescence findings. Despite typically presenting a less severe course than IgG-driven pemphigus, precise diagnosis and aggressive treatment with steroids and dapsone are imperative to avert relapses. Given the potential association with underlying malignancies or rheumatological and gastrointestinal disorders, a thorough physical examination and pertinent testing are essential for comprehensive patient evaluation.

This activity reviews a better understanding of IgA pemphigus, its clinical nuances, and the latest evidence-based management strategies. In addition, the interplay between circulating IgA antibodies and specific keratinocyte cell surface autoantigens is discussed. By empowering healthcare professionals with valuable insights and tools, this activity aims to optimize patient care for this complex and rare condition, thereby enhancing their competence in managing IgA pemphigus effectively.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the clinical presentation and characteristic features of IgA pemphigus, including painful and pruritic vesiculopustular eruptions and associated intraepidermal blistering.

  • Differentiate IgA pemphigus from other blistering skin diseases based on clinical manifestations, histopathology, and immunofluorescence findings.

  • Apply evidence-based treatment strategies for IgA pemphigus, including aggressive treatment with steroids and dapsone, to prevent recurrence and promote healing.

  • Coordinate multidisciplinary care seamlessly, facilitating transitions between healthcare professionals and specialties to provide continuous and integrated management of IgA pemphigus throughout the patient's journey.

  • Outline the pharmacologic therapy as it applies to IgA Pemphigus

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurse Practitioners: StatPearls designates this activity for 1.00 ANCC contact hour(s), which includes 0.5 hour(s) of pharmacology. NPs should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Dariush O. on 3/2/2023

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