4.9 out of 5 (21 Reviews)



Pharmacology Credits


Post Assessment Questions


Start Date

1 Sep 2023

Last Review Date

1 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes

Need Help?  If you have a system or content concerns, please contact

Activity Description

Afatinib, a tyrosine kinase inhibitor, is a widely used medication for non-small cell lung carcinoma. Afatinib is a targeted therapy that irreversibly inhibits the ErbB family of tyrosine kinases. It is the first-line FDA-approved indication to treat locally advanced or metastatic non-small cell lung cancer (NSCLC) that harbors nonresistant epidermal growth factor receptor (EGFR) mutations, and the second-line treatment of advanced squamous non-small cell lung cancer (NSCLC). Afatinib is also under investigation as monotherapy in patients with HER2-positive breast cancer who had progressed despite trastuzumab treatment. This activity educates health care providers on the indications, mechanism of action, adverse reactions, and toxicity. It also reviews the necessity of enhancing health care outcomes by improving the interprofessional approach to managing the drug.

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the mechanism of action of afatinib.
  • Describe the possible adverse effects of afatinib.
  • Summarize the appropriate monitoring for patients using afatinib.
  • Review interprofessional team strategies for enhancing care coordination and communication to advance afatinib use and improve outcomes.
  • Outline the indications of Afatinib


StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.


Nurse Practitioners: StatPearls designates this activity for 1.00 ANCC contact hour(s), which includes 1.00 hour(s) of pharmacology. NPs should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact


This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.




Alana H. on 8/23/2021

thomas on 8/30/2021

Adam T. on 10/17/2021

John S. on 11/24/2021

Anne C. on 3/28/2022

Stephen A. on 6/1/2022

Diane L. on 6/2/2022

Shannon j. on 6/27/2022

Nicole F. on 8/30/2022

Sara M. on 9/20/2022

Li Mei L. on 11/22/2022

Chet B. on 12/5/2022

Li Mei L. on 2/7/2023

Daniel H. on 4/13/2023

Daniel H. on 6/9/2023

Amber S. on 6/12/2023

Michele N. on 7/8/2023

Dawn B. on 8/22/2023

Allynda H. on 8/29/2023

Kelly K. on 8/26/2023

Richard D. on 9/22/2023

Unlimited Nurse Practitioner CE

Stay up to date on the latest medical knowledge with 6772 CE activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 8043 hours of CE.

Single Activity

Take this single activity

$39 1 activity

6 Month Unlimited Nurse Practitioner CE

Access to all the Unlimited Nurse Practitioner CE activities in all specialties.

$379 per half year per user

1 Year Unlimited Nurse Practitioner CE

Access to all the Unlimited Nurse Practitioner CE activities in all specialties.

$579 per 1 year per user