Overview

4.6 out of 5 (8 Reviews)

Credits

1.50

Pharmacology Credits

0.0

Post Assessment Questions

7

Start Date

1 Sep 2023

Last Review Date

25 Feb 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes


 
Need Help?  If you have a system or content concerns, please contact support@statpearls.com

Activity Description

Fanconi anemia is the most common cause of inherited bone marrow failure due to a rare autosomal recessive genetic disorder involving all 3 blood cell lines in which homozygous or heterozygous mutations result in pathogenic alleles, including point mutations, duplications, splicing defects, and deletions. These genetic mutations of Fanconi anemia genes cause an accruement of chromosomal damage due to the cell's inability to conduct repairs. These genetic mutations in the Fanconi anemia pathway lead to cells that cannot properly repair DNA damage, resulting in genomic instability, subsequent pancytopenia, and an increased susceptibility to cytotoxic agents, ultraviolet radiation, spontaneous deformation, and predisposition to malignancies. Additionally, Fanconi anemia affects almost all organs of the body.

Fanconi anemia is also thought of as an inherited form of aplastic anemia. The disorder may also predispose patients to the development of hematologic and solid tumors. A Fanconi anemia diagnosis is typically confirmed with a chromosomal fragility test, which remains the gold standard. Management of Fanconi anemia primarily includes supportive therapy, hematopoeitic stem cell transplantation, and androgen treatment. This activity for healthcare professionals aims to enhance learners' competence in selecting appropriate diagnostic tests, managing Fanconi anemia, and fostering effective interprofessional teamwork to improve outcomes.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the etiology of Fanconi anemia and what is to be expected in terms of disease progression.

  • Determine the appropriate evaluation of Fanconi anemia, including special genetic testing and the advantages and shortcomings of available treatments.

  • Compare the management options available for Fanconi anemia with special attention to the age groups involved.

  • Determine the best interprofessional team strategies for improving care coordination to improve patient outcomes.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurse Practitioners: StatPearls designates this activity for 1.50 ANCC contact hour(s), which includes 0 hour(s) of pharmacology. NPs should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Deborah Z. on 5/12/2021

MOSFER A. on 6/28/2022

Christine U. on 6/20/2022

Dr Sruthi G. on 6/24/2023

thanks

Valentine C. on 8/3/2023

Diana S. on 9/21/2023

Halina J. on 1/11/2024

Steven S. on 2/27/2024

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