Ace The SPEX Exam

Be prepared for the Federation of State Medical Boards® with 5,830 Questions that our experts have selected to simulate the real exam.

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About the Question Bank

Our review is designed to help you maximize your score on the SPEX Exam. StatPearls questions and articles are based on our experts review of the Federation of State Medical Boards® topics. Each review course is designed to empower you to assess your knowledge and understanding of medical principles and concepts found on the SPEX Exam.

Multiple-choice questions

We have 5,830 Multiple-choice 1st, 2nd, and 3rd order questions with four detailed teaching points linked to 3,293 PubMed indexed review articles related to the SPEX Examination. You can customize practice questions to system and clinical SPEX Student subject areas. In addition, you will have access to a pre- and post-test SPEX Exam to help you target learning and identify areas that need further study. Analytics and reports allow you to compare your scores to other students.

Achieve top scores

The StatPearls SPEX prep questions, SPEX review questions, and SPEX test questions will help you achieve a top score on the SPEX Examination. 2,406 authors and 59 editors have contributed to the development of the SPEX Exam content, which is continuously refined and updated to improve your learning experience.

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SPEX Exam Overview

  • How many hours is the SPEX Exam?

    The SPEX Exam is 6 hours.

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SPEX Exam MCQs (5,830)

Our question bank for the SPEX Exam covers four Cognitive Difficulty Levels:

Level 1

27 Questions

Level 2

564 Questions

Level 3

4,201 Questions

Level 4

1,038 Questions

  • Allergy and Immunology - 297 questions
  • Cardiovascular - 1523 questions
  • Musculoskeletal - 1042 questions
  • Ears Nose and Throat - 303 questions
  • Endocrine and Metabolism - 734 questions
  • Ophthalmology - 250 questions
  • Gastrointestinal and Nutrition - 1261 questions
  • Renal, Urinary and Electrolytes - 656 questions
  • Human Growth and Development - 225 questions
  • Gynecologic - 242 questions
  • Hematology and Oncology - 976 questions
  • Infectious Diseases - 1548 questions
  • Skin & Subcutaneous Tissue - 580 questions
  • Nervous - 1334 questions
  • Pregnancy, Childbirth & Puerperium - 228 questions
  • Psychiatric/Behavioral & Substance Use Disorder - 513 questions
  • Pulmonary & Critical Care - 918 questions
  • Poisoning & Environmental Exposure - 849 questions
  • Biostatistics and Epidemiology - 198 questions
  • Dental - 29 questions
  • Reproductive - 80 questions
  • Sexuality and Gender - 19 questions
  • Social Sciences (Ethics/Legal/Professional) - 92 questions
  • Traumatic Injuries - 203 questions
  • Manage Care and Comply Regulations - 134 questions
  • Promote Safety and Minimize Infection - 135 questions
  • Health Promotion & Maintenance (Prevent Problems) - 355 questions
  • Basic Care and Comfort (Assist Daily Living Tasks) - 45 questions
  • Pharm/Parenteral Therapy (Drugs/Vital Signs) - 1102 questions
  • Reduction Risk (Post Procedure) - 97 questions
  • Physiological Adaptation (Care Ill Patients) - 4249 questions
  • Psychosocial (Mental Health Patient/Family) - 301 questions
  • Professional Practice - 117 questions
  • Process (Analysis, Assess, Eval, Implement, Plan) - 5281 questions
  • Caring (Hope and Support) - 41 questions
  • Communication/Documentation (Oral, Written, EMR) - 53 questions
  • Teaching/Learning (Promotes Behavior Change) - 52 questions
  • Culture/Spiritualilty (Beliefs, Practices, Ethics) - 17 questions
  • Causes - 3468 questions
  • Classification - 527 questions
  • Differential - 3424 questions
  • Evaluation Diagnostic Tests - 1796 questions
  • Evaluation Lab - 1971 questions
  • Evaluation Monitoring - 581 questions
  • Evaluation Nuclear Medicine - 19 questions
  • Evaluation Procedures - 1111 questions
  • Evaluation Radiologic - 1684 questions
  • Health Maint Prevention Public Health - 263 questions
  • History Physical - 6772 questions
  • Legal - 51 questions
  • Patient Education - 401 questions
  • Prognosis Complications - 3402 questions
  • Toxicology - 352 questions
  • Treatment Medical - 3337 questions
  • Treatment Occupation/Physical Therapy - 63 questions
  • Treatment Prehospital/EMS/Disaster - 61 questions
  • Treatment Radiation - 27 questions
  • Treatment Rehabilitation - 34 questions
  • Treatment Surgical - 738 questions
  • Healthcare Ethics - 64 questions
  • Clinical Education - 130 questions
  • Environmental - 25 questions
  • Palliative - 34 questions
  • Treatment Manipulative - 10 questions
  • Airway Management - 61 questions
  • Pain Management - 80 questions
  • Sedation and Analgesic Management - 20 questions
  • Organ and Tissue Donation - 4 questions
  • Ventilatory Management - 29 questions
  • Research and Evidence-Based Medicine - 69 questions
  • Resource Utilization - 24 questions
  • Vulnerable Populations - 84 questions
  • Therapeutics (Drug treatment) - 1742 questions
  • Biostatics and Calculations - 14 questions
  • Drug Information - 1157 questions
  • Pharmaceutics (Safely dosing medications) - 438 questions
  • Pharmacokinetics (Drug movement in body) - 231 questions

SPEX Exam Articles (3,293)

We link each review question to its peer-reviewed, PubMed-indexed article from StatPearls authors and editors.
We make it easy for you to reinforce topic areas you excel at and fill knowledge gaps with source material.