Our review is designed to help you maximize your score on the SPEX Exam. StatPearls questions and articles are linked directly to Federation of State Medical Boards® content outlines. Each review course is designed to empower you to assess your knowledge and understanding of medical principles and concepts found on the SPEX Exam.
About the Question Bank
We have 13,311 Multiple-choice 1st, 2nd, and 3rd order questions with four detailed teaching points linked to 4,736 PubMed indexed review articles related to the SPEX Examination. You can customize practice questions to anatomical and clinical SPEX Student subject areas. In addition, you will have access to a 250 question pre- and post-test SPEX Exam to help you target learning and identify areas that need further study. Analytics and reports allow you to compare your scores to other students.
Achieve top scores
The StatPearls SPEX prep questions, SPEX review questions, and SPEX test questions will help you achieve a top score on the SPEX Examination. 3,548 authors and 48 editors have contributed to the development of the SPEX Exam content, which is continuously refined and updated to improve your learning experience.
SPEX Exam Overview
How many hours is the SPEX Exam?
The SPEX Exam is 6 hours.
How many questions is the SPEX Exam?
The SPEX Exam is 240 questions.
What topics are covered on the SPEX Exam?
Topics include: General Principles – 1.5%, Individual Organ Systems – 76.5%, Immune System, Blood and Lymphoreticular System, Behavioral Health, Nervous System & Special Senses, Skin & Subcutaneous Tissue, Musculoskeletal System, Cardiovascular System, Respiratory System, Gastrointestinal System, Renal & Urinary System, Pregnancy, Childbirth, & the Puerperium, Female Reproductive System & Breast, Male Reproductive System, Endocrine System, Multisystem Processes & Disorders, and Biostatistics and Epidemiology/Population Health and Interpretation of Medical Literature/Social Sciences – 22%
SPEX Exam MCQs (13,311)
Our question bank for the SPEX Exam covers four Cognitive Difficulty Levels:
- Allergy and Immunology - 517 questions
- Cardiovascular - 2558 questions
- Connective Tissue - 346 questions
- Ears Nose and Throat - 752 questions
- Endocrine and Metabolic - 1400 questions
- Eyes - 497 questions
- Gastrointestinal - 2206 questions
- Genetics - 404 questions
- Genitourinary - 716 questions
- Growth and Development - 456 questions
- Gynecologic - 619 questions
- Hematologic - 920 questions
- Infectious - 2778 questions
- Integument - 1171 questions
- Musculoskeletal - 1772 questions
- Nervous - 2456 questions
- Nutrition - 255 questions
- Obstetric - 658 questions
- Oncologic - 1310 questions
- Psychiatric Mental Health - 829 questions
- Pulmonary - 1654 questions
- Renal - 796 questions
- Surgery - 1156 questions
- Toxicology - 754 questions
- Trauma - 1187 questions
- Manage Care and Comply Regulations - 236 questions
- Promote Safety and Minimize Infection - 102 questions
- Health Promotion & Maintenance (Prevent Problems) - 348 questions
- Basic Care and Comfort (Assist Daily Living Tasks) - 60 questions
- Pharm/Parenteral Therapy (Drugs/Vital Signs) - 1216 questions
- Reduction Risk (Post Procedure) - 133 questions
- Physiological Adaptation (Care Ill Patients) - 3029 questions
- Psychosocial (Mental Health Patient/Family) - 354 questions
- Process (Analysis, Assess, Eval, Implement, Plan) - 4008 questions
- Caring (Hope and Support) - 31 questions
- Communication/Documentation (Oral, Written, EMR) - 77 questions
- Teaching/Learning (Promotes Behavior Change) - 40 questions
- Culture/Spiritualilty (Beliefs, Practices, Ethics) - 24 questions
- Causes - 6531 questions
- Classification - 1328 questions
- Differential - 6216 questions
- Epidemiology - 402 questions
- Evaluation Diagnostic Tests - 3500 questions
- Evaluation Lab - 3938 questions
- Evaluation Monitoring - 934 questions
- Evaluation Nuclear Medicine - 38 questions
- Evaluation Procedures - 2192 questions
- Evaluation Radiologic - 3603 questions
- Health Maint Prevention Public Health - 421 questions
- History Physical - 14118 questions
- Legal - 75 questions
- Pathophysiology - 6425 questions
- Patient Education - 638 questions
- Prognosis Complications - 6966 questions
- Toxicology - 545 questions
- Treatment Medical - 6268 questions
- Treatment Occupation/Physical Therapy - 109 questions
- Treatment Prehospital - 98 questions
- Treatment Radiation - 58 questions
- Treatment Rehabilitation - 83 questions
- Treatment Surgical - 1608 questions
- Healthcare Ethics - 130 questions
- Clinical Education - 170 questions
- Therapeutics (Drug treatment) - 1211 questions
- Biostatics and Calculations - 3 questions
- Drug Information - 968 questions
- Pharmaceutics (Safely dosing medications) - 436 questions
- Pharmacokinetics (Drug movement in body) - 69 questions
SPEX Exam Articles (4,736)
Laparoscopic cholecystectomy is a minimally invasive surgical procedure for removal of a diseased gallbladder. This technique essentially has repla ...
Primary care, sports medicine, and orthopedic surgeons commonly manage shoulder injuries and shoulder pain. Some reports in the literature cite tha ...
Viral hepatitis, a significant health care burden worldwide, is defined as virally mediated liver inflammation. Numerous viruses are known to ...
Iodine is an essential micronutrient that has a crucial role in metabolism. It is oxidized to produce iodine-containing thyroid hormones ...
Assisting patients with basic hygiene not only creates a personal connection between the health care provider and the patient but also is vital to ...
During the Fifth Annual Meeting of the American Venous Forum 1993, John Porter suggested a classification for venous disease, just like the TNM (tu ...
Postoperative wound infection is a common healthcare problem. The process of wound infection is complex and involves an interplay between several b ...
Fetal growth restriction (FGR) affects about 3% to 7% of all pregnancies.&nbs ...
Urinary retention is the inability to void urine voluntarily. It can be acute or chronic. It is a common medical problem across the globe, and ...
The adrenal is an endocrine organ that has two physiological functions. The outer adrenal cortex produces steroid hormones, including glu ...
Entheses are boney insertion sites of tendons and ligaments. Enthesopathies are defined as the pathologies that affect the entheses.
Acute pharyngitis is one of the most common complaints that a physician encounters in the ambulatory care setting, accounting for approximately 12 ...
Genital warts (condyloma acuminatum) are the clinical manifestations of a sexually transmitted infection caused by some types of human pa ...
Facial nerve palsy is a common presentation to primary care providers, the emergency department, and otolaryngologists. Trauma accounts for 10% to ...
Biliary strictures or bile duct strictures refer to segments of narrowing of the intrahepatic and/or extrahepatic biliary ductal system. When narro ...
Scott C Dulebohn MD Associate Professor ETSU, Meharry, LMU FAANS Johnson City TN
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