Our review is designed to help you maximize your score on the SPEX Exam. StatPearls questions and articles are linked directly to Federation of State Medical Boards® content outlines. Each review course is designed to empower you to assess your knowledge and understanding of medical principles and concepts found on the SPEX Exam.
We have 13,645 Multiple-choice 1st, 2nd, and 3rd order questions with four detailed teaching points linked to 4,836 PubMed indexed review articles related to the SPEX Examination. You can customize practice questions to anatomical and clinical SPEX Student subject areas. In addition, you will have access to a 250 question pre- and post-test SPEX Exam to help you target learning and identify areas that need further study. Analytics and reports allow you to compare your scores to other students.
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The StatPearls SPEX prep questions, SPEX review questions, and SPEX test questions will help you achieve a top score on the SPEX Examination. 3,636 authors and 49 editors have contributed to the development of the SPEX Exam content, which is continuously refined and updated to improve your learning experience.
SPEX Exam Overview
How many hours is the SPEX Exam?
The SPEX Exam is 6 hours.
How many questions is the SPEX Exam?
The SPEX Exam is 240 questions.
What topics are covered on the SPEX Exam?
Topics include: General Principles – 1.5%, Individual Organ Systems – 76.5%, Immune System, Blood and Lymphoreticular System, Behavioral Health, Nervous System & Special Senses, Skin & Subcutaneous Tissue, Musculoskeletal System, Cardiovascular System, Respiratory System, Gastrointestinal System, Renal & Urinary System, Pregnancy, Childbirth, & the Puerperium, Female Reproductive System & Breast, Male Reproductive System, Endocrine System, Multisystem Processes & Disorders, and Biostatistics and Epidemiology/Population Health and Interpretation of Medical Literature/Social Sciences – 22%
SPEX Exam MCQs (13,645)
Our question bank for the SPEX Exam covers four Cognitive Difficulty Levels:
- Allergy and Immunology - 531 questions
- Cardiovascular - 2617 questions
- Connective Tissue - 354 questions
- Ears Nose and Throat - 764 questions
- Endocrine and Metabolic - 1457 questions
- Eyes - 502 questions
- Gastrointestinal - 2250 questions
- Genetics - 412 questions
- Genitourinary - 727 questions
- Growth and Development - 457 questions
- Gynecologic - 625 questions
- Hematologic - 948 questions
- Infectious - 2864 questions
- Integument - 1202 questions
- Musculoskeletal - 1794 questions
- Nervous - 2500 questions
- Nutrition - 271 questions
- Obstetric - 676 questions
- Oncologic - 1323 questions
- Psychiatric Mental Health - 887 questions
- Pulmonary - 1702 questions
- Renal - 808 questions
- Surgery - 1177 questions
- Toxicology - 786 questions
- Trauma - 1210 questions
- Manage Care and Comply Regulations - 262 questions
- Promote Safety and Minimize Infection - 103 questions
- Health Promotion & Maintenance (Prevent Problems) - 357 questions
- Basic Care and Comfort (Assist Daily Living Tasks) - 62 questions
- Pharm/Parenteral Therapy (Drugs/Vital Signs) - 1308 questions
- Reduction Risk (Post Procedure) - 133 questions
- Physiological Adaptation (Care Ill Patients) - 3315 questions
- Psychosocial (Mental Health Patient/Family) - 383 questions
- Process (Analysis, Assess, Eval, Implement, Plan) - 4384 questions
- Caring (Hope and Support) - 33 questions
- Communication/Documentation (Oral, Written, EMR) - 78 questions
- Teaching/Learning (Promotes Behavior Change) - 42 questions
- Culture/Spiritualilty (Beliefs, Practices, Ethics) - 26 questions
- Causes - 6722 questions
- Classification - 1355 questions
- Differential - 6554 questions
- Epidemiology - 415 questions
- Evaluation Diagnostic Tests - 3626 questions
- Evaluation Lab - 4080 questions
- Evaluation Monitoring - 985 questions
- Evaluation Nuclear Medicine - 38 questions
- Evaluation Procedures - 2214 questions
- Evaluation Radiologic - 3656 questions
- Health Maint Prevention Public Health - 432 questions
- History Physical - 14473 questions
- Legal - 81 questions
- Pathophysiology - 6631 questions
- Patient Education - 656 questions
- Prognosis Complications - 7221 questions
- Toxicology - 570 questions
- Treatment Medical - 6421 questions
- Treatment Occupation/Physical Therapy - 108 questions
- Treatment Prehospital - 99 questions
- Treatment Radiation - 57 questions
- Treatment Rehabilitation - 83 questions
- Treatment Surgical - 1632 questions
- Healthcare Ethics - 135 questions
- Clinical Education - 203 questions
- Therapeutics (Drug treatment) - 1294 questions
- Biostatics and Calculations - 3 questions
- Drug Information - 996 questions
- Pharmaceutics (Safely dosing medications) - 451 questions
- Pharmacokinetics (Drug movement in body) - 69 questions
SPEX Exam Articles (4,836)
Hypotension is a decrease in systemic blood pressure below accepted low values. While there is not an accepted standard hypotensive value, pressure ...
Nonidiopathic interstitial pulmonary fibrosis (non-IPF) describes a group of interstitial lung diseases (ILD) that cause inflammation and fibrosis ...
A plica is a band of thick, fibrotic tissue that extends from the synovial capsule of a joint. Plica can be present in multiple joints, but this ar ...
Similar to other first-generation, or typical antipsychotics, thioridazine is a medication FDA approved to treat schizophrenia and schizophren ...
Pulmonary artery catheterization (PAC) is a procedure in which an intravascular catheter is inserted through a central vein (femoral, jugular, ante ...
Superior mesenteric artery syndrome is a rare cause of proximal small bowel obstruction and is linked to notable morbidity and mortality when the d ...
Leptomeningeal carcinomatosis(LC), also known as "leptomeningeal metastasis" or "carcinomatosis meningitis," is involvement by cancer of pia and ar ...
Ashman phenomenon was first described in 1947 by Dr. Gouaux and Dr. Ashman. In their initial description, they showed that the earlier in the cycle ...
Conn syndrome was named after J. W. Conn who first described it in 1955, in a patient who had hypertension with an aldosterone-producing adenoma. T ...
An umbilical hernia is a ventral hernia located at or near the umbilicus. The European Hernia Society classification for abdominal wall hernias def ...
Historically, James Hope was one of the first physicians to recommend methods to recognize benign and innocent murmurs. In his 1942 textbook, Hope ...
Leuprolide is an FDA-approved gonadotropin-releasing hormone (GnRH) agonist used for the management of endometriosis, uterine leiomyomata (also kno ...
Diabetes mellitus (DM) is a disease spectrum ranging from classic insulinopenic type 1 diabetes (T1DM) at one end to classic insulin-resistant type ...
In women, breast cancer is number one in incidence and mortality when compared to all cancers.&nb ...
is a non-tuberculous mycobacterium first isolated from tubercles obtained at necropsy of dead saltwater fish in an a ...
Scott C Dulebohn MD Associate Professor ETSU, Meharry, LMU FAANS Johnson City TN
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