Ace The SPEX Exam

Be prepared for the Federation of State Medical Boards® with 6,976 Questions that our experts have selected to simulate the real exam.

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About the Question Bank

Our review is designed to help you maximize your score on the SPEX Exam. StatPearls questions and articles are based on our experts review of the Federation of State Medical Boards® topics. Each review course is designed to empower you to assess your knowledge and understanding of medical principles and concepts found on the SPEX Exam.

Multiple-choice questions

We have 6,976 Multiple-choice 1st, 2nd, and 3rd order questions with four detailed teaching points linked to 3,820 PubMed indexed review articles related to the SPEX Examination. You can customize practice questions to anatomical and clinical SPEX Student subject areas. In addition, you will have access to a pre- and post-test SPEX Exam to help you target learning and identify areas that need further study. Analytics and reports allow you to compare your scores to other students.

Achieve top scores

The StatPearls SPEX prep questions, SPEX review questions, and SPEX test questions will help you achieve a top score on the SPEX Examination. 3,083 authors and 41 editors have contributed to the development of the SPEX Exam content, which is continuously refined and updated to improve your learning experience.

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SPEX Exam Overview

  • How many hours is the SPEX Exam?

    The SPEX Exam is 6 hours.

  • How many questions is the SPEX Exam?

  • What topics are covered on the SPEX Exam?

SPEX Exam MCQs (6,976)

Our question bank for the SPEX Exam covers four Cognitive Difficulty Levels:

Level 1

28 Questions

Level 2

681 Questions

Level 3

4,961 Questions

Level 4

1,306 Questions

  • Allergy and Immunology - 301 questions
  • Cardiovascular - 1539 questions
  • Connective Tissue - 207 questions
  • Ears Nose and Throat - 334 questions
  • Endocrine and Metabolic - 884 questions
  • Eyes - 285 questions
  • Gastrointestinal - 1340 questions
  • Genetics - 209 questions
  • Genitourinary - 371 questions
  • Growth and Development - 225 questions
  • Gynecologic - 269 questions
  • Hematologic - 507 questions
  • Infectious - 1662 questions
  • Integument - 622 questions
  • Musculoskeletal - 1013 questions
  • Nervous - 1511 questions
  • Nutrition - 158 questions
  • Obstetric - 277 questions
  • Oncologic - 708 questions
  • Psychiatric Mental Health - 528 questions
  • Pulmonary - 952 questions
  • Renal - 463 questions
  • Surgery - 602 questions
  • Toxicology - 496 questions
  • Trauma, Injury, Safety, and Violence - 667 questions
  • Teeth/Oral - 20 questions
  • Reproductive - 3 questions
  • Sexuality and Gender - 5 questions
  • Psychiatric Addiction - 53 questions
  • Pharmacology - 56 questions
  • Thoracic - 28 questions
  • Anatomy - 9 questions
  • Behavioral - 46 questions
  • Histology - 1 questions
  • Neuroanatomy - 6 questions
  • Pathology - 10 questions
  • Biochemistry - 3 questions
  • Physiology - 16 questions
  • Embryology - 2 questions
  • Manage Care and Comply Regulations - 144 questions
  • Promote Safety and Minimize Infection - 84 questions
  • Health Promotion & Maintenance (Prevent Problems) - 235 questions
  • Basic Care and Comfort (Assist Daily Living Tasks) - 40 questions
  • Pharm/Parenteral Therapy (Drugs/Vital Signs) - 899 questions
  • Reduction Risk (Post Procedure) - 75 questions
  • Physiological Adaptation (Care Ill Patients) - 2612 questions
  • Psychosocial (Mental Health Patient/Family) - 350 questions
  • Professional Practice - 36 questions
  • Process (Analysis, Assess, Eval, Implement, Plan) - 3449 questions
  • Caring (Hope and Support) - 29 questions
  • Communication/Documentation (Oral, Written, EMR) - 52 questions
  • Teaching/Learning (Promotes Behavior Change) - 34 questions
  • Culture/Spiritualilty (Beliefs, Practices, Ethics) - 16 questions
  • Causes - 3726 questions
  • Classification - 627 questions
  • Differential - 3614 questions
  • Epidemiology - 228 questions
  • Evaluation Diagnostic Tests - 1962 questions
  • Evaluation Lab - 2307 questions
  • Evaluation Monitoring - 530 questions
  • Evaluation Nuclear Medicine - 23 questions
  • Evaluation Procedures - 1178 questions
  • Evaluation Radiologic - 1984 questions
  • Health Maint Prevention Public Health - 266 questions
  • History Physical - 8017 questions
  • Legal - 49 questions
  • Pathophysiology - 3581 questions
  • Patient Education - 401 questions
  • Prognosis Complications - 3922 questions
  • Toxicology - 362 questions
  • Treatment Medical - 3669 questions
  • Treatment Occupation/Physical Therapy - 68 questions
  • Treatment Prehospital/EMS/Disaster - 56 questions
  • Treatment Radiation - 29 questions
  • Treatment Rehabilitation - 42 questions
  • Treatment Surgical - 790 questions
  • Healthcare Ethics - 64 questions
  • Clinical Education - 97 questions
  • Environmental - 3 questions
  • Treatment Manipulative - 1 questions
  • Airway Management - 3 questions
  • Pain Management - 16 questions
  • Sedation and Analgesic Management - 4 questions
  • Ventilatory Management - 1 questions
  • Biostatistics - 2 questions
  • Research and Evidence-Based Medicine - 8 questions
  • Resource Utilization - 6 questions
  • Vulnerable Populations - 23 questions
  • Therapeutics (Drug treatment) - 987 questions
  • Biostatics and Calculations - 5 questions
  • Drug Information - 752 questions
  • Pharmaceutics (Safely dosing medications) - 325 questions
  • Pharmacokinetics (Drug movement in body) - 66 questions