Metatarsal Fractures

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Continuing Education Activity

Metatarsal fractures are one of the most common foot injuries encountered in trauma and emergency. They usually occur as a result of direct trauma to the forefoot. The common presentation involves foot pain and swelling with difficulty in ambulating without support. The treatment involves conservative management in the form of cast or operative treatment in selected cases. This activity reviews the evaluation and management of metatarsal fractures and highlights the role of the interprofessional team in evaluating and managing patients with this condition.

Objectives:

  • Describe the most common etiologies of metatarsal fractures.
  • Describe the common presentation of a patient with metatarsal fractures.
  • Identify the various radiological investigations required for diagnosing metatarsal fractures.
  • Explain the treatment considerations for patients with metatarsal fractures.

Introduction

Metatarsal fractures are relatively common injuries of the foot. The main goal of treatment is to restore the alignment of all metatarsals, hence maintaining the arches of the forefoot and thereby resulting in the distribution of a normal weight under the head of metatarsals. If properly managed, these injuries are easy to treat and have a favorable prognosis.[1][2][3] On the other hand, these injuries may also result in prolonged disability in scenarios of malunion or non-union. Metatarsalgia is one of the common sequelae in cases with failure in achieving the ascertained goal of management.[4]

Etiology

The most common etiology for metatarsal fractures is either direct or indirect trauma. Such injuries may vary from a simple isolated metatarsal fracture to crush injuries involving multiple fractures and drastic soft tissue compromise.[4] Direct trauma can occur due to the fall of heavy objects on the foot and is usually seen in industrial workers. Indirect trauma occurs when there is a twisting movement of the hindfoot and leg while the forefoot is fixed. Supination injuries to the foot may result in avulsion fractures of the fifth metatarsal base because of the tension generated over the peroneus brevis tendon and the lateral cord of plantar aponeurosis.[1][5][6][7] 

The Lisfranc joint complex consists of the tarsometatar­sal joints. The Lisfranc fracture-dislocation can result due to falling from height or stairs. The common mechanisms of injury are either longitudinal compression of the foot or rotation around a fixed forefoot. In the former mechanism, the metatarsal head remains fixed while body weight lies over the hindfoot, especially against the base of metatarsals.[7] 

The other variety of fractures that are commonly seen in metatarsal bones is stress fractures which result from a small amount of repetitive force and are commonly associated with ballet dancers, athletes and soldiers, hence termed “march fracture.”[4][8] Multiple risk factors associated with stress fractures include hyper load syndrome, Morton’s foot, anorexia nervosa, amenorrhea, and prolonged hypoestrogenism.[4][7] 

Insufficiency fractures can also be seen in metatarsal bones, which occur due to normal stress loading over a weakened bone. Such injuries are usually seen in osteoporosis patients and postmenopausal women.[7]

Epidemiology

Metatarsal fractures are one of the most common injuries to the foot. The frequency of metatarsal fractures is about ten times compared with that of Lisfranc fracture-dislocations.[9] Metatarsal fractures consist of 61% of all fractures of the foot in children. Most metatarsal fractures in children occur at the fifth (41%) and the first (19%) ray.[10] The fifth metatarsal is the most commonly fractured (23%), followed by the third metatarsal in cases of industrial injuries.[4]

History and Physical

Patients with such injuries usually complain about difficulty in bearing weight or excruciating pain on ambulation. Proper history taking in such patients regarding suggestive mechanisms of injury is essential. Clinically, there is tenderness, crepitus, bruising, deformity, and swelling over the forefoot. Gross deformities are usually seen only with complex injuries, which include multiple fractures and dislocations.[4] 

Sometimes it is hard to differentiate soft tissue injury and fracture of the base of the fifth metatarsal because the pain and swelling for both injuries lie just inferior to the lateral malleolus. Hence thorough examination and proper evaluation are needed in cases of metatarsal injuries.[7]

Evaluation

The radiographic evaluation consists of standard views of the foot, including anteroposterior, 45 degrees oblique, and lateral projection. To diagnose metatarsal overload, additional weight-bearing roentgenograms, including the lateral view of the foot and tangential view of metatarsal heads, are helpful. Acute stress fractures are usually not detected with a standard X-ray. To confirm the diagnosis of stress fractures, the x-rays can be repeated after 10 to 14 days of the onset of symptoms. A radiolucent resorption gap can be seen around the fracture, which confirms the diagnosis.[4][11][12]

Alternatively, MRI and Technetium scans can be ordered as they have a high sensitivity in detecting such fractures. In scenarios of multiple fractures of the base of metatarsals, computed tomography is advised to rule out the possibility of Lisfranc fracture-dislocation.[4] Stress X-rays which include passive adduction and abduction of the forefoot, can be performed under local anesthesia to reveal ligamentous instability at the Lisfranc joint. While interpreting roentgenograms, anatomical variants such as the os vesalianum (within the peroneus brevis tendon), the os peroneum (within the peroneus longus tendon), the os cuneometatarsale, and the os intermetatarseum have to be kept in mind along with the apophysis at the fifth metatarsal base which is visible between 11 and 14 years in boys and 9 and 11 years in girls.[5]

Metatarsal fractures can be topographically classified into metatarsal head fractures, sub-capital fractures, midshaft fractures, and basal fractures. Fifth metatarsal fractures have been described by Dameron and later on by Quill as Zone 1 (tuberosity avulsion fractures), Zone 2 (metaphyseal-diaphyseal junction fractures), and Zone 3 (proximal shaft stress fractures). Lisfranc fracture-dislocation is characterized by traumatic disruption between the base of the second metatarsal and the medial cuneiform. They have been classified into two types: homolateral and divergent. In the homolateral type, there is lateral displacement of first to fifth metatarsals or second to fifth metatarsals where the first metatarsophalangeal joint remains congruent, while in the divergent type, there is lateral displacement of second to fifth metatarsals with medial displacement of the first metatarsal.[5][6][5][7]

Lisfranc fracture-dislocations are commonly associated with multiple foot fractures, including the second metatarsal base, cuboid bone, the shaft of the other metatarsals, navicular bone, and dislocations of the medial and middle cuneonavicular joints. When comparing with other metatarsal bones, the base of the second metatarsal remains relatively fixed. Hence, it is involved in both of the varieties of Lisfranc fracture-dislocation. In as many as 20% of cases, this pattern of fracture-dislocation remains undiagnosed due to poor judgment of the alignment of metatarsals. This type of injury should be highly suspected if a gap of more than 5 mm is noted in between the medial and middle cuneiforms or in between the bases of the first and second metatarsals.[7]

Treatment / Management

Conservative management can be offered to undisplaced metatarsal fractures, including stress fractures which include adhesive strapping, short leg walking cast for 4 to 6 weeks, or a non-weight-bearing cast for 3 weeks followed by a walking cast for another 3 weeks, except in professional athletes to avoid long duration of immobilization. In second to fourth metatarsal fractures, which are displaced only in the frontal plane without shortening, can also be managed nonoperatively.[13][14] The first and fifth metatarsal fractures which are displaced in the horizontal plane should be managed operatively to avoid secondary deformities like posttraumatic hallux valgus and digitus quintus varus.[4] 

Metatarsal fractures displaced in the sagittal plane may result in painful callosities, metatarsalgia, and neuroma formation; hence need to be managed operatively.[4] Shereff suggests the reduction of any metatarsal fracture with angulation of more than 10 degrees and displacement of more than 3 to 4 mm. Lisfranc joint complex fractures, if displaced more than 2 mm and involving more than 30% of the joint, need to be managed operatively with open reduction and internal fixation.[15] 

Management of open metatarsal fractures includes thorough debridement, wound lavage, fracture stabilization using external or minimal internal fixation followed by the postoperative use of antibiotics, and planned second-look surgery. Multiple implants are available for metatarsal fractures, including K-wires, mini fragment plates, and interfragmentary screws from the AO small fragment system (3.5 mm) and the AO Foot Set (2.7 mm).

First Metatarsal

The first metatarsal plays an important role in maintaining the balance of the foot as the majority of weight passed through it compared to the other metatarsals.  Any disruption of it may result in a dysfunctional foot. As there is a lack of ligamentous support between the first and adjacent metatarsals, the chances of displacement are high. Fractures that show instability and significant displacement warrant operative intervention.[16] 

First metatarsal fractures are difficult to keep reduced after closed reduction because of the pull of the intrinsic and extrinsic muscles and hence commonly require internal fixation. In the shaft of the first metatarsal fractures, stable fixation can be obtained with the help of two crossed K-wires of 1.8-2 mm diameter. The comminuted fractures can be managed with plates that should be placed over the medial-plantar aspect because of the minimum soft tissue cover on the dorsal aspect.[4] 

If there is extensive comminution of the first metatarsal fracture, then external fixation is more favorable as compared to internal fixation accounting for the poor soft tissue condition and high chances of postoperative infection. The main goal in such fractures is to maintain the length of the first metatarsal to prevent the transfer of metatarsalgia. Intra-articular fractures of the head of the first metatarsal should be carefully evaluated to assess the congruity of the joint. Open reduction and internal fixation will be the preferred treatment option for the fractures of the first metatarsal head, which shows joint incongruity to achieve desired functional outcome. Cancellous bone grafting can be considered in the management of metatarsal head fractures which show significant impaction.[16] 

First, metatarsal fractures that involve the metatarsophalangeal and the tarsometatarsal joint should be reconstructed anatomically to avoid posttraumatic arthritis. To avoid deformities such as hallux valgus or varus, the anatomical reduction must be obtained in the transverse (horizontal) plane.[4]

Second-Fourth Metatarsal

The second metatarsal is more stabilized compared to the other central metatarsals due to the presence of the Lisfranc ligament, which runs between the second metatarsal base and the medial cuneiform. The rest of the central metatarsal bases are aligned together with the help of multiple strong ligamentous structures which lies on both plantar and dorsal aspect. Because of the stable proximal articulations and strong soft tissue support, there is minimum movement permitted, resulting in a high level of intrinsic stability. In cases of severe traumatic injuries, if displacement occurs, these central metatarsals will tend to displace as a single unit.[16][17]

The goal of management is to restore the length in the sagittal plane, while dislocation in the transverse plane can be tolerated to some extent. The management of choice for simple fractures is retrograde percutaneous pinning.[4][17] K-wires are inserted distally through the metatarsal head under fluoroscopic guidance. While doing so, plantarflexion of the distal fragment and dorsiflexion of the adjacent toe helps in achieving the reduction. 

The pros of the percutaneous pinning technique include the ability to preserve the vascularity of fractured bone with negligible disruption of the soft tissue envelope. In scenarios where closed manipulation failed to provide the desired outcome, open procedures using minimally invasive options need to be performed, which will help achieve the reduction by providing direct visualization of fractured ends with minimum soft tissue dissection. Comminuted fractures can be managed using mini-fragment plates. Metatarsalgia can be commonly seen in central metatarsal fractures managed conservatively due to malunion and parabola disruption.[16]

Fifth Metatarsal

Fractures of the shaft should be managed operatively because conservative management usually results in displacement due to loose ligamentous connections to the fourth metatarsal. Undisplaced Jones fracture shows delayed fracture healing due to the poor blood supply and instability.[18] In acute scenarios, they can be managed with restricted weight-bearing and immobilization for 6 to 8 weeks. Operative management should be considered in scenarios of professional athletes or cases of delayed fracture healing beyond ten weeks.[19] 

Nowadays, the trend is being shifted towards operative management, incorporating the benefits like early mobilization, high chances of union, and better functional outcomes. One of the common forms of operative management is intramedullary screw fixation. As cannulated screws are easy to insert hence, they are commonly used. Various studies proved the superiority of solid screw over the cannulated screw concerning its strength.[20] 

Other operative treatment options include tension band wiring, percutaneous pinning, and external fixation. Avulsion fractures that involve a small portion of the tuberosity can be managed by excision. In scenarios where fractures showing displacement more than 2mm and involving more than 30% of the joint should be managed by the operative intervention.[16] 

When considering the management of the proximal shaft fractures, we need to differentiate among non-union, delayed union, stress fractures, and acute traumatic injuries.[21] All of these entities will present with almost similar clinical features.[22] To make a diagnosis, one must consider a history of trauma, sclerosis of the medullary canal, width of the fracture gap, and the periosteal reaction at the fracture site. Conservative management can be offered to patients who are being diagnosed with acute stress fractures.[21][23][24] 

In patients where the diagnosis of delayed healing has been made, intramedullary fixation using screws along with bone grafting can be offered.[21][24][25] In scenarios where a nonunion is the diagnosis, further management can be decided based on the periosteal reaction.[4] 

If on roentgenogram features of periosteal reaction are present such patients can be managed by either intramedullary fixation using a screw or extramedullary fixation using mini fragment plates. If roentgenogram suggests sclerosis of medullary canal with no signs of periosteal reaction, in such patients, multimodal approach including curettage of the sclerotic bone, stabilization of fracture ends, and corticocancellous bone grafting can be advised.[21][24][4]

Differential Diagnosis

The common differential diagnosis of metatarsal fractures includes ankle sprains, plantar fascia ruptures, peroneal tendon injuries, sesamoiditis, Freiberg infraction, osteomyelitis, neuropathic osteoarthropathy, tenosynovitis, bursitis, calluses, and Morton neuromas. These can be diagnosed separately with the help of meticulous clinical examination along with relevant radiological investigations.

Prognosis

Undisplaced or minimally displaced metatarsal fractures show a good prognosis if provided adequate rest and immobilization. Fractures of the base of metatarsals show good healing potential as they are located in cancellous bone.[4] Fractures of the first metatarsal show good healing potential because of the good amount of cancellous bone. Central metatarsal fractures show rapid healing due to the inherent stability and the abundance of vascularity from the surrounding musculature. Jones fracture shows poor healing potential due to the scarcity of vascular supply and many displacement forces. In contrast to jones's fracture, avulsion fractures of the fifth metatarsal tuberosity show a good tendency to heal.[16]

Complications

The most common complication noticed after non-operative management of metatarsal fractures includes metatarsalgia, which is secondary to mal-union or residual deformity(16). The other common complications include non-union, delayed union, posttraumatic deformities like digitus quintus varus, and arthrosis.[4] The less common complications include nonunion, implant failure, hardware irritation, and sural nerve injury.[16]

Deterrence and Patient Education

Patients having foot pain for long-duration should get their foot pathology evaluated, as stress fractures of metatarsals can present without any antecedent history of trauma and can remain undiagnosed. These fractures may be missed on plain radiographic examination and should be evaluated with higher imaging investigations. Also, patients with metatarsal fractures should get them adequately treated and rehabilitated as neglected fractures can lead to painful conditions like Morton's neuroma, with persistent disability.

Enhancing Healthcare Team Outcomes

As a patient with a foot injury, including probable metatarsal fracture, presents to the clinic/ emergency, proper evaluation should be done. The radiological evaluation involves certain stress/ regular views of the foot; the radiology technician should be well aware of the positions of the foot in which various x-ray views need to be obtained. In cases with open injuries and neurovascular injuries, the services of a plastic surgeon may be required. Besides, in stress fractures occurring in elderly patients, thorough workup needs to be done by an endocrinologist as well as a geriatric medicine expert. As these injuries sometimes lead to foot and ankle stiffness, appropriate physiotherapy advice should be sought.



(Click Image to Enlarge)
X-ray of right foot anteroposterior and oblique view showing a displaced fracture of distal shaft 2nd metatarsal (>4 mm displacement) and a minimally displaced fracture of proximal shaft 3rd metatarsal.
X-ray of right foot anteroposterior and oblique view showing a displaced fracture of distal shaft 2nd metatarsal (>4 mm displacement) and a minimally displaced fracture of proximal shaft 3rd metatarsal.
Contributed by Vivek Tiwari, MS

(Click Image to Enlarge)
The x-ray of left foot anteroposterior and oblique views showing Jones fracture.
The x-ray of left foot anteroposterior and oblique views showing Jones fracture.
Contributed by Vivek Tiwari, MS

(Click Image to Enlarge)
An anteroposterior and oblique x-ray of left foot showing fracture of 2nd-5th Metatarsal neck
An anteroposterior and oblique x-ray of left foot showing fracture of 2nd-5th Metatarsal neck
Contributed by Vivek Tiwari

(Click Image to Enlarge)
An x-ray of foot showing K-wire fixation for fracture 2nd and 3rd metatarsal shaft
An x-ray of foot showing K-wire fixation for fracture 2nd and 3rd metatarsal shaft
Contributed by Vivek Tiwari

(Click Image to Enlarge)
Clinical image along with an oblique view x-ray of the right foot showing open fracture of 4th metatarsal shaft
Clinical image along with an oblique view x-ray of the right foot showing open fracture of 4th metatarsal shaft
Contributed by Vivek Tiwari
Article Details

Article Author

Udit Agrawal

Article Editor:

Vivek Tiwari

Updated:

7/24/2022 10:53:23 PM

PubMed Link:

Metatarsal Fractures

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