Cancer of the Oral Mucosa


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Start Date

1 Sep 2023

Last Review Date

15 Mar 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes

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Activity Description

Cancer of the oral mucosa originates from the mucosa lining of various structures within the oral cavity, including the lips, cheeks, teeth, gums, anterior two-thirds of the tongue, the floor of the mouth, the floor of the mouth, the hard palate, and the retromolar trigone posterior to the wisdom teeth. Primary risk factors for oral mucosal cancer include smoking and alcohol consumption, particularly when combined, while additional risks stem from human papillomavirus infection and stem cell transplants. Clinicians must have a nuanced understanding of the anatomical boundaries and relationships within the oral cavity, including the lower edge of the soft palate, the division between the anterior and posterior sections of the tongue, and the anterior pillars of the tonsils. This knowledge helps differentiate oral cavity structures, particularly the soft palate, from oropharyngeal structures, such as the faucial and lingual tonsils (the tongue base), aiding in accurate diagnosis and treatment planning.

Cancer of the oral mucosa treatment typically revolves around surgery as the mainstay, often with adjuvant radiotherapy for advanced-stage cancers. Single-modality therapy may address early-stage cancers, whereas late-stage cancers necessitate multimodality approaches. This activity explores the primary risk factors of oral mucosal cancers, emphasizing the significant adverse effects of combined smoking and alcohol consumption. This activity involves a multidisciplinary healthcare team elucidating the crucial aspects of the optimal treatment approach for comprehensive diagnosis, investigation, and treatment of patients with oral mucosal cancer. An enhanced understanding of the multifaceted aspects of oral cavity mucosal cancer facilitates its application in clinical settings, ultimately leading to improved patient care.

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, nurse practitioners, and dentists.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify risk factors associated with cancer of the oral mucosa, including tobacco and alcohol use, human papillomavirus infection, and stem cell transplants.

  • Implement appropriate treatment strategies based on the stage of cancer of the oral mucosa, including surgery, radiotherapy, chemotherapy, or immunotherapy.

  • Select optimal treatment modalities considering patient-specific factors such as age, overall health, and treatment preferences for managing cancer of the oral mucosa in clinical practice.

  • Collaborate with multidisciplinary healthcare teams, including oncologists, surgeons, radiologists, and pathologists, to comprehensively manage cancer of the oral mucosa and maintain the overall quality of life for patients.


StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

StatPearls, LLC is an ADA CERP Recognized Provider. ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providers of continuing dental education. ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry. Concerns or complaints about a CE provider may be directed to the Commission of Continuing Provider Recognition at

Dentists: StatPearls, LLC designates this continuing education activity for 1.50 ADA credit(s). Dentists should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact


This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.




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