Proximal Humeral Epiphysiolysis

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Continuing Education Activity

Proximal humeral epiphysiolysis, colloquially termed Little League shoulder, is a stress injury of the epiphyseal cartilage of the proximal humerus that occurs exclusively in athletes whose growth plate has not yet closed. It classically affects youth baseball pitchers between the ages of 11 and 16, though theoretically, it could happen at any age up until growth plate closure, which typically happens between the ages of 18 and 21. Although this condition is typically described in youth baseball players and throwing athletes, there have also been cases reported in competitive gymnasts and tennis players. This activity describes the pathophysiology, evaluation, and management of proximal humeral epiphysiolysis and highlights the interprofessional team's role in the management of this condition.


  • Describe a typical history consistent with proximal humeral epiphysiolysis.
  • Review common physical exam findings consistent with proximal humeral epiphysiolysis.
  • Summarize the role of imaging in the workup of proximal humeral epiphysiolysis.
  • Explain interprofessional team strategies for improving care coordination and communication to advance the recognition and management of proximal humeral epiphysiolysis and improve outcomes.


Proximal humeral epiphysiolysis (Little League shoulder) is a shear or stress injury of the epiphyseal cartilage of the proximal humerus. Little League shoulder has also been referred to as osteochondrosis of the proximal humeral epiphysis and rotation stress fracture of the proximal humeral epiphyseal plate. Little League shoulder occurs exclusively in athletes whose physis remains open before the closure of the growth plate, and it classically affects youth baseball pitchers. Since growth plate closure occurs between 18 and 21 years old, injuries can theoretically occur until that age. However, the typical age at presentation is between 11 and 16 years old. Although it is typically described in youth baseball players and throwing athletes, there have also been cases reported in competitive gymnasts[1] and tennis players.[2]


Little League shoulder is the result of excessive rotational and distractional forces that occur with repetitive overhead throwing. This repetitive microtrauma leads to cartilage damage of the proximal humeral epiphysis. It is believed that the rotational force has a larger role than the distractional force in developing the condition.[3]

The epiphyseal plate is at increased risk for injury because it is weaker than neighboring ligaments. This distinction is significant and explains why this age group is more likely to suffer growth plate injuries, whereas adults would suffer tendon or ligament injuries. The epiphyseal growth cartilage is also at higher risk for injury due to repetitive action than adult cartilage.[3] Another factor increasing the risk of injury in adolescents is bone growth, which can cause strength and flexibility imbalances. Additionally, the growth plate is more susceptible to torsion than it is to tension.[3]

Another factor posited to contribute to Little League Shoulder is the angle of humeral retrotorsion. A recent case study suggested a rapid change in the humeral retrotorsion angle may increase susceptibility to growth plate damage.[4] However, other studies state the increased retrotorsion does not appear to cause symptoms.[3]


Little League shoulder is most common in youth baseball players. One study looked at 2055 baseball players between the ages of 9 and 12. They found that 13.4% reported shoulder pain in their throwing arm. Of those patients with pain, 41 agreed to have x-rays taken of his or her shoulder. Of these 41, 36.6% had findings of Little League shoulder on x-ray. While this is a small sample size, this places the prevalence of Little League shoulder among all baseball players in this study, with and without pain, at 4.9%.[5]

Another study of 1563 youth baseball players found that 15.9% had shoulder pain, although this was not specific to Little League shoulder.[6]


There are 2 broad phases of the throwing motion. These are the arm-cocking phase followed by the acceleration phase. The pathophysiology leading to Little League shoulder is believed to be the significant external rotational torque on the humeral shaft during the final part of the arm-cocking phase, just before the acceleration phase. This torque likely leads to the deformation of the proximal humeral epiphysis cartilage, which eventually leads to proximal humeral epiphysiolysis.

As mentioned above, the distractional force has a lesser role than the rotational force. The distractional force that occurs during the throwing motion results in the rotator cuff muscles causing a force on the proximal humerus to keep the glenohumeral joint intact. The rotator cuff muscles exert a force on the proximal humerus because their insertion site is proximal to the proximal humeral epiphysis.

History and Physical

During an examination of a child suspected of having Little League shoulder, it is important to ask about a history of shoulder or elbow injury. Shoulder and elbow injury history are both important because they could both lead to a child consciously or subconsciously change their throwing mechanics to ease prior elbow pain. Altering mechanics may increase the risk of injury by distributing forces throughout the humerus differently. The examiner should also ask the patient if they have had a recent growth spurt as this likely places him or her at higher risk for proximal humeral epiphysiolysis.

Symptoms typically include a progressive onset of generalized shoulder pain when throwing. As symptoms advance, pain can develop with simply lifting the arm; there may even be pain at rest. However, until the late stages of the condition, the patient will likely report that symptoms improve with rest. Additional symptoms can include diminished throwing accuracy and/or velocity. Up to 13% of patients can have elbow pain in addition to shoulder pain.[2]

On physical exam, patients are often tender to palpation over the growth plate on the lateral aspect of the proximal humerus. There may be subtle swelling; otherwise, inspection and palpation are generally normal. Decreased range of motion and muscle weakness can also be present depending on the severity of the case. Most frequently, weakness is due to guarding secondary to pain.


Diagnosis is primarily clinical suspicion. In most athletes, radiographs will show a normal physis. Diagnosis can be confirmed by radiographs, which may reveal a wide proximal humeral physis on an anteroposterior (AP) view of the shoulder with the arm in external rotation. Chronic changes such as sclerosis, demineralization, and fragmentation can also be seen.[5] Musculoskeletal ultrasound can also help diagnosis in the hands of a practitioner experienced with musculoskeletal ultrasound. Ultrasound findings include increased hypoechoic swelling around the affected shoulder, which is not seen on the contralateral side. Although often unnecessary, MRI can be used to confirm the diagnosis if x-rays are negative. MRI would reveal edema around the physis.

Treatment / Management

If treated at the onset of pain, discontinuation of activities that cause pain can prevent an overt stress fracture of the proximal humerus's growth plate. Prior to stress fracture occurring, pain often resolves with rest. Once a stress fracture occurs, the pain does not resolve with rest, and the skill level while throwing decreases.

The treatment for Little League shoulder is 3 to 6 months of rest and discontinuation of overhead activity. Treatment can advance to core muscle and rotator cuff strengthening with a physical therapist once there is no pain at rest. Once the range of motion, strength, and scapular motion returns to normal, then a gradual return to throwing by participation in a structured throwing program and subsequent return to competition can follow.[7]

Surgery is not indicated for proximal humeral epiphysiolysis.

Differential Diagnosis

The differential diagnosis includes:

  • Impingement syndrome
  • Rotator cuff injury
  • Biceps tendonitis
  • Labral tear
  • Subdeltoid bursitis

Less common conditions on the differential diagnosis include:

  • Tumors of the upper arm
  • C5 radiculopathy
  • Thoracic outlet syndrome


One study determined a 3-grade classification of Little League shoulder based on radiographic findings.

  • Grade I: Widening of the epiphyseal plate in the lateral area only
  • Grade II: Widening in all areas of the epiphyseal plate and metaphyseal demineralization
  • Grade III: Slipped epiphysis[5]

An older classification system proposes 4 grades based on the level of displacement.

  • Grade I: Less than 5 mm
  • Grade II: Less than one-third of the width of the shaft
  • Grade III: Between one-third and two-thirds of the width of the shaft
  • Grade IV: Greater than two-thirds the width of the shaft[8]


The majority of children with this condition will return to pre-injury activity level if they have sufficient rest from throwing and a gradual, structured return to play. One study found that adequate shoulder flexibility was related to a pain-free return to baseball.[9]

Similarly, another study found that Little League shoulder patients with glenohumeral internal rotation deficit (GIRD), a decreased rotational range of motion of the shoulder, were associated with a 3-times increased risk of recurrence of Little League shoulder.[2]


Complications are rare, but they include growth plate anomalies such as:

  • Glenohumeral joint subluxation
  • Humeral head osteonecrosis
  • Early closure of the physis leading to limb length discrepancy


Management of Little League shoulder does not necessarily require a consultation with a sports medicine physician or orthopedic surgeon as long as the managing clinician is practicing within his or her expertise and is confident he or she is making the correct diagnosis.

Deterrence and Patient Education

This injury is due to overuse from repetitive throwing. Therefore, deterrence includes avoiding excessive throwing. Current literature proposes limiting pitch counts to prevent primary onset and recurrence of Little League shoulder. Stretching before and after sport and icing the shoulder after throwing is also important. Further, it is recommended to take one season off of throwing per year. United States Baseball and Major League Baseball recommend age-based pitch counts and days of rest based on the pitch count to guide youth players and coaches on a safe amount of throwing-induced stress. Proper biomechanics of a child’s throwing motion should also be encouraged to ensure the mechanics do not cause excess stress on the shoulder. One study found that 80.6 degrees of shoulder abduction and 10.7 degrees of horizontal shoulder adduction minimized the shear forces on the shoulder, while increased shoulder abduction increased anterior force.[10]

Other mechanical factors that can increase torque on the shoulder and elbow and therefore increase the risk of injury include:

  • Altered knee flexion at ball release
  • early trunk rotation
  • loss of shoulder rotational range of motion
  • increased elbow flexion at ball release
  • high pitch velocity
  • increased pitcher fatigue[11]

When the child returns to throw, the practitioner should discourage the child from taking NSAIDs before throwing to avoid covering up inflammatory etiologies of pain.

Pearls and Other Issues

  • Proximal humeral epiphysiolysis is related to excess repetitive throwing with inadequate recovery time and is classically seen in youth baseball pitchers between ages 11 and 16.
  • Prevention includes optimizing throwing mechanics, limiting pitch counts, and taking adequate time off from throwing. Time off throwing includes adequate time off in-between pitching during the season and to take one season of the year completely off of throwing.
  • Patients present with non-focal shoulder pain while throwing and tenderness to palpation over the lateral aspect of the humerus. Muscle weakness and limited range of motion can also be found.
  • The x-ray finding indicative of Little League shoulder is widening of the proximal humeral physis.
  • Treatment is rest from throwing for 3 to 6 months. Once the pain is gone, core and rotator cuff strengthening exercises are recommended with a gradual return to throwing.

Enhancing Healthcare Team Outcomes

The best outcomes with Little League shoulder will occur when the treating clinician is working in close contact with a physical therapist who can confidently perform strengthening exercises for the rotator cuff and core muscles. An orthopedic nurse can also help coordinate care and activity between the team's various disciplines. The physical therapist should also be familiar with a throwing program. Parents and coaches should also be included in the treatment team for Little League shoulder as they have the power to ensure adequate rest for the athlete after an injury has occurred. Parents and coaches can also limit throwing to appropriate levels to mitigate the risk of developing primary or recurrent shoulder and other arm injuries. This sort of interprofessional healthcare team provides the best prognosis in recovery from Little League shoulder cases. [Level 5]



Kyle Casadei


John Kiel


4/3/2023 5:35:32 PM



Dalldorf PG,Bryan WJ, Displaced Salter-Harris type I injury in a gymnast. A slipped capital humeral epiphysis? Orthopaedic review. 1994 Jun     [PubMed PMID: 8065812]


Heyworth BE, Kramer DE, Martin DJ, Micheli LJ, Kocher MS, Bae DS. Trends in the Presentation, Management, and Outcomes of Little League Shoulder. The American journal of sports medicine. 2016 Jun:44(6):1431-8. doi: 10.1177/0363546516632744. Epub 2016 Mar 16     [PubMed PMID: 26983458]


Sabick MB, Kim YK, Torry MR, Keirns MA, Hawkins RJ. Biomechanics of the shoulder in youth baseball pitchers: implications for the development of proximal humeral epiphysiolysis and humeral retrotorsion. The American journal of sports medicine. 2005 Nov:33(11):1716-22     [PubMed PMID: 16093541]


Greenberg EM, Turner C, Huse C, Ganley TJ, McClure P, Lawrence JT. Changes in humeral retrotorsion and the development of little league shoulder: A case study. Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine. 2018 Nov:34():49-54. doi: 10.1016/j.ptsp.2018.08.005. Epub 2018 Aug 14     [PubMed PMID: 30176396]

Level 3 (low-level) evidence


Kanematsu Y, Matsuura T, Kashiwaguchi S, Iwase T, Suzue N, Iwame T, Fukuta S, Hamada D, Goto T, Sairyo K. Epidemiology of shoulder injuries in young baseball players and grading of radiologic findings of Little Leaguer's shoulder. The journal of medical investigation : JMI. 2015:62(3-4):123-5. doi: 10.2152/jmi.62.123. Epub     [PubMed PMID: 26399334]


Matsuura T,Suzue N,Iwame T,Arisawa K,Fukuta S,Sairyo K, Epidemiology of shoulder and elbow pain in youth baseball players. The Physician and sportsmedicine. 2016     [PubMed PMID: 26831221]


Sgroi TA,Zajac JM, Return to Throwing after Shoulder or Elbow Injury. Current reviews in musculoskeletal medicine. 2018 Mar     [PubMed PMID: 29450826]


Neer CS 2nd,Horwitz BS, Fractures of the proximal humeral epiphysial plate. Clinical orthopaedics and related research. 1965 Jul-Aug     [PubMed PMID: 5832735]


Harada M, Takahara M, Maruyama M, Kondo M, Uno T, Takagi M, Mura N. Outcome of conservative treatment for Little League shoulder in young baseball players: factors related to incomplete return to baseball and recurrence of pain. Journal of shoulder and elbow surgery. 2018 Jan:27(1):1-9. doi: 10.1016/j.jse.2017.08.018. Epub 2017 Oct 17     [PubMed PMID: 29054382]


Tanaka H,Hayashi T,Inui H,Muto T,Ninomiya H,Nakamura Y,Yoshiya S,Nobuhara K, Estimation of Shoulder Behavior From the Viewpoint of Minimized Shoulder Joint Load Among Adolescent Baseball Pitchers. The American journal of sports medicine. 2018 Oct     [PubMed PMID: 30095975]


Chalmers PN, Wimmer MA, Verma NN, Cole BJ, Romeo AA, Cvetanovich GL, Pearl ML. The Relationship Between Pitching Mechanics and Injury: A Review of Current Concepts. Sports health. 2017 May/Jun:9(3):216-221. doi: 10.1177/1941738116686545. Epub 2017 Jan 1     [PubMed PMID: 28107113]