[1]
Von Hofe J, Bates GW. Ovulation induction. Obstetrics and gynecology clinics of North America. 2015 Mar:42(1):27-37. doi: 10.1016/j.ogc.2014.09.007. Epub 2014 Dec 5
[PubMed PMID: 25681838]
[2]
American College of Obstetricians and Gynecologists' Committee on Practice Bulletins—Gynecology. ACOG Practice Bulletin No. 194: Polycystic Ovary Syndrome. Obstetrics and gynecology. 2018 Jun:131(6):e157-e171. doi: 10.1097/AOG.0000000000002656. Epub
[PubMed PMID: 29794677]
[3]
Ma H, Quan X, Chen X, Dong Y. [Flying needling therapy combined with clomiphene for ovulation failure in polycystic ovary syndrome:a randomized controlled trial]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. 2016 Nov 12:36(11):1161-1165. doi: 10.13703/j.0255-2930.2016.11.015. Epub
[PubMed PMID: 29231300]
Level 1 (high-level) evidence
[4]
Costello MF, Garad RM, Hart R, Homer H, Johnson L, Jordan C, Mocanu E, Qiao J, Rombauts L, Teede HJ, Vanky E, Venetis CA, Ledger WL. A Review of Second- and Third-line Infertility Treatments and Supporting Evidence in Women with Polycystic Ovary Syndrome. Medical sciences (Basel, Switzerland). 2019 Jun 26:7(7):. doi: 10.3390/medsci7070075. Epub 2019 Jun 26
[PubMed PMID: 31247909]
Level 2 (mid-level) evidence
[5]
Creanga AA, Bradley HM, McCormick C, Witkop CT. Use of metformin in polycystic ovary syndrome: a meta-analysis. Obstetrics and gynecology. 2008 Apr:111(4):959-68. doi: 10.1097/AOG.0b013e31816a4ed4. Epub
[PubMed PMID: 18378757]
Level 1 (high-level) evidence
[6]
Myers ER, Silva SG, Hafley G, Kunselman AR, Nestler JE, Legro RS, National Institute of Child Health and Human Development Reproductive Medicine Network. Estimating live birth rates after ovulation induction in polycystic ovary syndrome: sample size calculations for the pregnancy in polycystic ovary syndrome trial. Contemporary clinical trials. 2005 Jun:26(3):271-80
[PubMed PMID: 15911461]
[7]
Mejia RB, Summers KM, Kresowik JD, Van Voorhis BJ. A randomized controlled trial of combination letrozole and clomiphene citrate or letrozole alone for ovulation induction in women with polycystic ovary syndrome. Fertility and sterility. 2019 Mar:111(3):571-578.e1. doi: 10.1016/j.fertnstert.2018.11.030. Epub 2019 Jan 22
[PubMed PMID: 30683591]
Level 1 (high-level) evidence
[8]
Katz DJ, Nabulsi O, Tal R, Mulhall JP. Outcomes of clomiphene citrate treatment in young hypogonadal men. BJU international. 2012 Aug:110(4):573-8. doi: 10.1111/j.1464-410X.2011.10702.x. Epub 2011 Nov 1
[PubMed PMID: 22044663]
[9]
Pelusi C, Giagulli VA, Baccini M, Fanelli F, Mezzullo M, Fazzini A, Bianchi N, Carbone MD, De Pergola G, Mastroroberto M, Morselli Labate AM, Pasquali R. Clomiphene citrate effect in obese men with low serum testosterone treated with metformin due to dysmetabolic disorders: A randomized, double-blind, placebo-controlled study. PloS one. 2017:12(9):e0183369. doi: 10.1371/journal.pone.0183369. Epub 2017 Sep 8
[PubMed PMID: 28886024]
Level 1 (high-level) evidence
[10]
Habous M, Giona S, Tealab A, Aziz M, Williamson B, Nassar M, Abdelrahman Z, Remeah A, Abdelkader M, Binsaleh S, Muir G. Clomiphene citrate and human chorionic gonadotropin are both effective in restoring testosterone in hypogonadism: a short-course randomized study. BJU international. 2018 Nov:122(5):889-897. doi: 10.1111/bju.14401. Epub 2018 Jun 14
[PubMed PMID: 29772111]
Level 1 (high-level) evidence
[11]
Patel DP, Brant WO, Myers JB, Presson AP, Johnstone EB, Dorais JA, Aston KI, Carrell DT, Hotaling JM. The safety and efficacy of clomiphene citrate in hypoandrogenic and subfertile men. International journal of impotence research. 2015 Nov-Dec:27(6):221-4. doi: 10.1038/ijir.2015.21. Epub 2015 Aug 20
[PubMed PMID: 26289907]
[12]
Miller GD, Moore C, Nair V, Hill B, Willick SE, Rogol AD, Eichner D. Hypothalamic-Pituitary-Testicular Axis Effects and Urinary Detection Following Clomiphene Administration in Males. The Journal of clinical endocrinology and metabolism. 2019 Mar 1:104(3):906-914. doi: 10.1210/jc.2018-01159. Epub
[PubMed PMID: 30295816]
[13]
Rozen TD. Complete alleviation of treatment refractory primary SUNCT syndrome with clomiphene citrate (a medicinal deep brain hypothalamic modulator). Cephalalgia : an international journal of headache. 2014 Oct:34(12):1021-4. doi: 10.1177/0333102414527647. Epub 2014 Mar 24
[PubMed PMID: 24662321]
[14]
Guay AT, Jacobson J, Perez JB, Hodge MB, Velasquez E. Clomiphene increases free testosterone levels in men with both secondary hypogonadism and erectile dysfunction: who does and does not benefit? International journal of impotence research. 2003 Jun:15(3):156-65
[PubMed PMID: 12904801]
[15]
Roth LW, Ryan AR, Meacham RB. Clomiphene citrate in the management of male infertility. Seminars in reproductive medicine. 2013 Jul:31(4):245-50. doi: 10.1055/s-0033-1345271. Epub 2013 Jun 17
[PubMed PMID: 23775379]
[16]
Adashi EY. Clomiphene citrate: mechanism(s) and site(s) of action--a hypothesis revisited. Fertility and sterility. 1984 Sep:42(3):331-44
[PubMed PMID: 6432584]
[17]
Wheeler KM, Sharma D, Kavoussi PK, Smith RP, Costabile R. Clomiphene Citrate for the Treatment of Hypogonadism. Sexual medicine reviews. 2019 Apr:7(2):272-276. doi: 10.1016/j.sxmr.2018.10.001. Epub 2018 Dec 3
[PubMed PMID: 30522888]
[18]
Liu Y, Chen Q, Yu S, Wang Y, He W, Chang HY, Wang B, Gao H, Long H, Wang L, Lyu Q, Ai A, Kuang Y. Progestin-primed ovarian stimulation with or without clomiphene citrate supplementation in normal ovulatory women undergoing in vitro fertilization/intracytoplasmic sperm injection: A prospective randomized controlled trial. Clinical endocrinology. 2018 Mar:88(3):442-452. doi: 10.1111/cen.13532. Epub 2018 Jan 4
[PubMed PMID: 29247457]
Level 1 (high-level) evidence
[19]
Davidson R, Motan T, Korownyk C. Clomiphene for anovulatory infertility. Canadian family physician Medecin de famille canadien. 2016 Jun:62(6):492
[PubMed PMID: 27303007]
[21]
Jones T, Ho JR, Gualtieri M, Bruno-Gaston J, Chung K, Paulson RJ, Bendikson KA. Clomiphene Stair-Step Protocol for Women With Polycystic Ovary Syndrome. Obstetrics and gynecology. 2018 Jan:131(1):91-95. doi: 10.1097/AOG.0000000000002418. Epub
[PubMed PMID: 29215516]
[22]
Berk-Krauss J, Bieber AK, Criscito MC, Grant-Kels JM, Driscoll MS, Keltz M, Pomeranz MK, Martires KJ, Liebman TN, Stein JA. Melanoma risk after in vitro fertilization: A review of the literature. Journal of the American Academy of Dermatology. 2018 Dec:79(6):1133-1140.e3. doi: 10.1016/j.jaad.2018.07.022. Epub 2018 Jul 25
[PubMed PMID: 30055204]
[23]
Farzinvash Z. A young woman with sudden visual field shimmering: A case report. Indian journal of ophthalmology. 2018 Oct:66(10):1504-1505. doi: 10.4103/ijo.IJO_515_18. Epub
[PubMed PMID: 30249855]
Level 3 (low-level) evidence
[24]
Vervaet BA, Nast CC, Jayasumana C, Schreurs G, Roels F, Herath C, Kojc N, Samaee V, Rodrigo S, Gowrishankar S, Mousson C, Dassanayake R, Orantes CM, Vuiblet V, Rigothier C, D'Haese PC, De Broe ME. Chronic interstitial nephritis in agricultural communities is a toxin-induced proximal tubular nephropathy. Kidney international. 2020 Feb:97(2):350-369. doi: 10.1016/j.kint.2019.11.009. Epub 2019 Nov 23
[PubMed PMID: 31892415]
[25]
Del Pup L, Peccatori FA, Levi-Setti PE, Codacci-Pisanelli G, Patrizio P. Risk of cancer after assisted reproduction: a review of the available evidences and guidance to fertility counselors. European review for medical and pharmacological sciences. 2018 Nov:22(22):8042-8059. doi: 10.26355/eurrev_201811_16434. Epub
[PubMed PMID: 30536354]
[26]
Scaparrotta A, Chiarelli F, Verrotti A. Potential Teratogenic Effects of Clomiphene Citrate. Drug safety. 2017 Sep:40(9):761-769. doi: 10.1007/s40264-017-0546-x. Epub
[PubMed PMID: 28547654]
[27]
Yano K, Ohashi K. Interprofessional team approach to infertility treatment in Japan. Reproductive medicine and biology. 2010 Mar:9(1):33-41. doi: 10.1007/s12522-009-0038-5. Epub 2009 Nov 17
[PubMed PMID: 29662423]
[28]
Jessup RL. Interdisciplinary versus multidisciplinary care teams: do we understand the difference? Australian health review : a publication of the Australian Hospital Association. 2007 Aug:31(3):330-1
[PubMed PMID: 17669052]
[29]
Chandrapal JC, Nielson S, Patel DP, Zhang C, Presson AP, Brant WO, Myers JB, Hotaling JM. Characterising the safety of clomiphene citrate in male patients through prostate-specific antigen, haematocrit, and testosterone levels. BJU international. 2016 Dec:118(6):994-1000. doi: 10.1111/bju.13546. Epub 2016 Jun 24
[PubMed PMID: 27226135]
[30]
Shi S, Hong T, Jiang F, Zhuang Y, Chen L, Huang X. Letrozole and human menopausal gonadotropin for ovulation induction in clomiphene resistance polycystic ovary syndrome patients: A randomized controlled study. Medicine. 2020 Jan:99(4):e18383. doi: 10.1097/MD.0000000000018383. Epub
[PubMed PMID: 31977842]
Level 1 (high-level) evidence
[31]
Teede HJ, Misso ML, Boyle JA, Garad RM, McAllister V, Downes L, Gibson M, Hart RJ, Rombauts L, Moran L, Dokras A, Laven J, Piltonen T, Rodgers RJ, Thondan M, Costello MF, Norman RJ, International PCOS Network. Translation and implementation of the Australian-led PCOS guideline: clinical summary and translation resources from the International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. The Medical journal of Australia. 2018 Oct 1:209(S7):S3-S8
[PubMed PMID: 30453865]
Level 1 (high-level) evidence
[32]
Franik S, Kremer JA, Nelen WL, Farquhar C. Aromatase inhibitors for subfertile women with polycystic ovary syndrome. The Cochrane database of systematic reviews. 2014 Feb 24:(2):CD010287. doi: 10.1002/14651858.CD010287.pub2. Epub 2014 Feb 24
[PubMed PMID: 24563180]
Level 1 (high-level) evidence
[33]
. Committee Opinion No. 663: Aromatase Inhibitors in Gynecologic Practice. Obstetrics and gynecology. 2016 Jun:127(6):e170-e174. doi: 10.1097/AOG.0000000000001484. Epub
[PubMed PMID: 27214191]
Level 3 (low-level) evidence
[34]
Rezk M, Shaheen AE, Saif El-Nasr I. Clomiphene citrate combined with metformin versus letrozole for induction of ovulation in clomiphene-resistant polycystic ovary syndrome: a randomized clinical trial. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 2018 Apr:34(4):298-300. doi: 10.1080/09513590.2017.1395838. Epub 2017 Oct 27
[PubMed PMID: 29076376]
Level 2 (mid-level) evidence