[1]
Dulguerov P,Marchal F,Gysin C, Frey syndrome before Frey: the correct history. The Laryngoscope. 1999 Sep;
[PubMed PMID: 10499057]
[2]
Dulguerov P,Marchal F,Gysin C, The bullet that hit a nerve: the history of Lucja Frey and her syndrome. The Journal of laryngology and otology. 2006 Dec;
[PubMed PMID: 17059631]
[3]
Blanc S,Bourrier T,Boralevi F,Sabouraud-Leclerc D,Pham-Thi N,Couderc L,Deschildre A,Dutau G,Albertini M,Tran A,Giovannini-Chami L, Frey Syndrome. The Journal of pediatrics. 2016 Jul;
[PubMed PMID: 27157448]
[4]
Scully C,Langdon J,Evans J, Marathon of eponyms: 6 Frey syndrome (Gustatory sweating). Oral diseases. 2009 Nov;
[PubMed PMID: 19824940]
[5]
Bonanno PC,Casson PR, Frey's syndrome: a preventable phenomenon. Plastic and reconstructive surgery. 1992 Mar;
[PubMed PMID: 1741468]
[6]
O'Neill JP,Condron C,Curran A,Walsh A, Lucja Frey--historical relevance and syndrome review. The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 2008 Jun;
[PubMed PMID: 18581755]
[7]
Wood CB,Netterville JL, Temporoparietal frey syndrome: An uncommon variant of a common syndrome. The Laryngoscope. 2019 Sep;
[PubMed PMID: 30570147]
[9]
Iwanaga J,Fisahn C,Watanabe K,Bobek SL,Ogata K,Tanoue R,Kusukawa J,Oskouian RJ,Tubbs RS, Parotid Branches of the Auriculotemporal Nerve: An Anatomical Study With Implications for Frey Syndrome. The Journal of craniofacial surgery. 2017 Jan;
[PubMed PMID: 27930465]
[10]
Ansari MH, Salivary gland tumors in an Iranian population: a retrospective study of 130 cases. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. 2007 Nov;
[PubMed PMID: 17954313]
Level 2 (mid-level) evidence
[11]
Vuhahula EA, Salivary gland tumors in Uganda: clinical pathological study. African health sciences. 2004 Apr;
[PubMed PMID: 15126188]
[12]
Pinkston JA,Cole P, Incidence rates of salivary gland tumors: results from a population-based study. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 1999 Jun;
[PubMed PMID: 10352436]
[14]
Singh N,Kohli M,Kohli H, Innovative technique to reduce incidence of Frey's syndrome after parotid surgery. The American surgeon. 2011 Mar;
[PubMed PMID: 21375851]
[15]
Neumann A,Rosenberger D,Vorsprach O,Dazert S, [The incidence of Frey syndrome following parotidectomy: results of a survey and follow-up]. HNO. 2011 Feb;
[PubMed PMID: 21181391]
Level 3 (low-level) evidence
[16]
Fiacchini G,Cerchiai N,Tricò D,Sellari-Franceschini S,Casani AP,Dallan I,Seccia V, Frey Syndrome, First Bite Syndrome, great auricular nerve morbidity, and quality of life following parotidectomy. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 2018 Jul;
[PubMed PMID: 29804129]
Level 2 (mid-level) evidence
[17]
Zeng XT,Tang XJ,Wang XJ,Li MZ,Guo Y,Huang W,Niu YM,Leng WD, AlloDerm implants for prevention of Frey syndrome after parotidectomy: a systematic review and meta-analysis. Molecular medicine reports. 2012 Apr;
[PubMed PMID: 22266670]
Level 1 (high-level) evidence
[18]
Hohman MH, Bhama PK, Hadlock TA. Epidemiology of iatrogenic facial nerve injury: a decade of experience. The Laryngoscope. 2014 Jan:124(1):260-5. doi: 10.1002/lary.24117. Epub 2013 Apr 18
[PubMed PMID: 23606475]
[19]
Lee CC,Chan RC,Chan JY, Predictors for Frey Syndrome Development After Parotidectomy. Annals of plastic surgery. 2017 Jul;
[PubMed PMID: 28609397]
[21]
Kragstrup TW,Christensen J,Fejerskov K,Wenzel A, Frey syndrome-an underreported complication to closed treatment of mandibular condyle fracture? Case report and literature review. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. 2011 Aug;
[PubMed PMID: 21496996]
Level 3 (low-level) evidence
[23]
Sethuraman G,Mancini AJ, Familial auriculotemporal nerve (Frey) syndrome. Pediatric dermatology. 2009 May-Jun;
[PubMed PMID: 19706092]
[24]
Guntinas-Lichius O,Gabriel B,Klussmann JP, Risk of facial palsy and severe Frey's syndrome after conservative parotidectomy for benign disease: analysis of 610 operations. Acta oto-laryngologica. 2006 Oct;
[PubMed PMID: 16923718]
[25]
Linder TE,Huber A,Schmid S, Frey's syndrome after parotidectomy: a retrospective and prospective analysis. The Laryngoscope. 1997 Nov;
[PubMed PMID: 9369396]
Level 2 (mid-level) evidence
[26]
Dulguerov P,Quinodoz D,Cosendai G,Piletta P,Marchal F,Lehmann W, Prevention of Frey syndrome during parotidectomy. Archives of otolaryngology--head
[PubMed PMID: 10448728]
[27]
Watkins PJ, Facial sweating after food: a new sign of diabetic autonomic neuropathy. British medical journal. 1973 Mar 10;
[PubMed PMID: 4144374]
[29]
Motz KM,Kim YJ, Auriculotemporal Syndrome (Frey Syndrome). Otolaryngologic clinics of North America. 2016 Apr;
[PubMed PMID: 26902982]
[30]
Myers EN,Conley J, Gustatory sweating after radical neck dissection. Archives of otolaryngology (Chicago, Ill. : 1960). 1970 Jun;
[PubMed PMID: 4315319]
[31]
Redleaf MI,McCabe BF, Gustatory otorrhea: Frey's syndrome of the external auditory canal. The Annals of otology, rhinology, and laryngology. 1993 Jun;
[PubMed PMID: 8512270]
[32]
Bakke M,Max Thorsen N,Bardow A,Dalager T,Eckhart Thomsen C,Regeur L, Treatment of gustatory sweating with low-dose botulinum toxin A: a case report. Acta odontologica Scandinavica. 2006 Jun;
[PubMed PMID: 16809188]
Level 3 (low-level) evidence
[33]
Wenzel GI,Draf W, [Unusually long latency before the appearance of Frey's syndrome after parotidectomy]. HNO. 2004 Jun;
[PubMed PMID: 15257402]
[34]
Durgut O,Basut O,Demir UL,Ozmen OA,Kasapoglu F,Coskun H, Association between skin flap thickness and Frey's syndrome in parotid surgery. Head
[PubMed PMID: 23471856]
[35]
Taylor SM,Yoo J,Matthews TW,Lampe HB,Trites JR, Frey's syndrome and parotidectomy flaps: A retrospective cohort study. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2000 Feb;
[PubMed PMID: 10652390]
Level 2 (mid-level) evidence
[36]
Govindaraj S,Cohen M,Genden EM,Costantino PD,Urken ML, The use of acellular dermis in the prevention of Frey's syndrome. The Laryngoscope. 2001 Nov;
[PubMed PMID: 11801985]
[37]
Balasundaram I,Nasser NA, Paraumbilical fat graft for the correction of contour deformity following parotidectomy and prevention of Frey syndrome. International journal of oral and maxillofacial surgery. 2016 Mar;
[PubMed PMID: 26439758]
[38]
Bonanno PC,Palaia D,Rosenberg M,Casson P, Prophylaxis against Frey's syndrome in parotid surgery. Annals of plastic surgery. 2000 May;
[PubMed PMID: 10805299]
[39]
Wille-Bischofberger A,Rajan GP,Linder TE,Schmid S, Impact of the SMAS on Frey's syndrome after parotid surgery: a prospective, long-term study. Plastic and reconstructive surgery. 2007 Nov;
[PubMed PMID: 18040182]
[40]
Yu LT,Hamilton R, Frey's syndrome: prevention with conservative parotidectomy and superficial musculoaponeurotic system preservation. Annals of plastic surgery. 1992 Sep;
[PubMed PMID: 1326250]
[41]
Allison GR,Rappaport I, Prevention of Frey's syndrome with superficial musculoaponeurotic system interposition. American journal of surgery. 1993 Oct;
[PubMed PMID: 8214303]
[42]
Barberá R,Castillo F,D'Oleo C,Benítez S,Cobeta I, Superficial musculoaponeurotic system flap in partial parotidectomy and clinical and subclinical Frey's syndrome. Cosmesis and quality of life. Head
[PubMed PMID: 23378265]
Level 2 (mid-level) evidence
[43]
Sultan MR,Wider TM,Hugo NE, Frey's syndrome: prevention with temporoparietal fascial flap interposition. Annals of plastic surgery. 1995 Mar;
[PubMed PMID: 7598387]
[44]
Kierner AC,Aigner M,Zelenka I,Riedl G,Burian M, The blood supply of the sternocleidomastoid muscle and its clinical implications. Archives of surgery (Chicago, Ill. : 1960). 1999 Feb;
[PubMed PMID: 10025452]
[45]
Filho WQ,Dedivitis RA,Rapoport A,Guimarães AV, Sternocleidomastoid muscle flap preventing Frey syndrome following parotidectomy. World journal of surgery. 2004 Apr;
[PubMed PMID: 15022023]
[46]
Curry JM,King N,Reiter D,Fisher K,Heffelfinger RN,Pribitkin EA, Meta-analysis of surgical techniques for preventing parotidectomy sequelae. Archives of facial plastic surgery. 2009 Sep-Oct;
[PubMed PMID: 19797095]
Level 1 (high-level) evidence
[47]
Kornblut AD, Sternocleidomastoid muscle transfer in the prevention of Frey's syndrome. The Laryngoscope. 1991 May;
[PubMed PMID: 2030639]
[48]
Sanabria A,Kowalski LP,Bradley PJ,Hartl DM,Bradford CR,de Bree R,Rinaldo A,Ferlito A, Sternocleidomastoid muscle flap in preventing Frey's syndrome after parotidectomy: a systematic review. Head
[PubMed PMID: 21472880]
Level 1 (high-level) evidence
[50]
Drobik C,Laskawi R, Frey's syndrome: treatment with botulinum toxin. Acta oto-laryngologica. 1995 May;
[PubMed PMID: 7653272]
[51]
Clayman MA,Clayman SM,Seagle MB, A review of the surgical and medical treatment of Frey syndrome. Annals of plastic surgery. 2006 Nov;
[PubMed PMID: 17060744]
[52]
Hays LL, The Frey syndrome: a review and double blind evaluation of the topical use of a new anticholinergic agent. The Laryngoscope. 1978 Nov;
[PubMed PMID: 362094]
Level 1 (high-level) evidence
[53]
HEMENWAY WG, Gustatory sweating and flushing. The auriculo-temporal syndrome--Frey's syndrome. The Laryngoscope. 1960 Jan;
[PubMed PMID: 14400950]
[55]
Smith RO Jr,Hemenway WG,Stevens KM,Ratzer ER, Jacobson's neurectomy for Frey's syndrome. American journal of surgery. 1970 Oct;
[PubMed PMID: 4319212]
[56]
Arad-Cohen A,Blitzer A, Botulinum toxin treatment for symptomatic Frey's syndrome. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2000 Feb;
[PubMed PMID: 10652397]
[57]
Cantarella G,Berlusconi A,Mele V,Cogiamanian F,Barbieri S, Treatment of Frey's syndrome with botulinum toxin type B. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2010 Aug;
[PubMed PMID: 20647122]
[58]
Beerens AJ,Snow GB, Botulinum toxin A in the treatment of patients with Frey syndrome. The British journal of surgery. 2002 Jan;
[PubMed PMID: 11851676]
[60]
Lawrence GW,Ovsepian SV,Wang J,Aoki KR,Dolly JO, Therapeutic effectiveness of botulinum neurotoxin A: potent blockade of autonomic transmission by targeted cleavage of only the pertinent SNAP-25. Neuropharmacology. 2013 Jul;
[PubMed PMID: 23485402]
[61]
Kreyden OP,Scheidegger EP, Anatomy of the sweat glands, pharmacology of botulinum toxin, and distinctive syndromes associated with hyperhidrosis. Clinics in dermatology. 2004 Jan-Feb;
[PubMed PMID: 15158544]
[62]
Tugnoli V,Marchese Ragona R,Eleopra R,Quatrale R,Capone JG,Pastore A,Montecucco C,De Grandis D, The role of gustatory flushing in Frey's syndrome and its treatment with botulinum toxin type A. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. 2002 Jun;
[PubMed PMID: 12269549]
[63]
Pomprasit M,Chintrakarn C, Treatment of Frey's syndrome with botulinum toxin. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. 2007 Nov;
[PubMed PMID: 18181326]
[64]
Hartl DM,Julieron M,LeRidant AM,Janot F,Marandas P,Travagli JP, Botulinum toxin A for quality of life improvement in post-parotidectomy gustatory sweating (Frey's syndrome). The Journal of laryngology and otology. 2008 Oct;
[PubMed PMID: 18289458]
Level 2 (mid-level) evidence
[65]
Matak I,Riederer P,Lacković Z, Botulinum toxin's axonal transport from periphery to the spinal cord. Neurochemistry international. 2012 Jul;
[PubMed PMID: 22580329]
[66]
Laccourreye O,Akl E,Gutierrez-Fonseca R,Garcia D,Brasnu D,Bonan B, Recurrent gustatory sweating (Frey syndrome) after intracutaneous injection of botulinum toxin type A: incidence, management, and outcome. Archives of otolaryngology--head
[PubMed PMID: 10190799]
[67]
de Bree R,Duyndam JE,Kuik DJ,Leemans CR, Repeated botulinum toxin type A injections to treat patients with Frey syndrome. Archives of otolaryngology--head
[PubMed PMID: 19289708]
[68]
Laskawi R,Drobik C,Schönebeck C, Up-to-date report of botulinum toxin type A treatment in patients with gustatory sweating (Frey's syndrome). The Laryngoscope. 1998 Mar;
[PubMed PMID: 9504611]
[69]
Blumenfeld RJ,Friedman JE, Intratympanic surgical treatment of frey's syndrome. Archives of otolaryngology (Chicago, Ill. : 1960). 1967 Jul;
[PubMed PMID: 4290826]
[70]
Dai XM,Liu H,He J,Tu MS,Yu LF,Liu L, Treatment of postparotidectomy Frey syndrome with the interposition of temporalis fascia and sternocleidomastoid flaps. Oral surgery, oral medicine, oral pathology and oral radiology. 2015 May;
[PubMed PMID: 25747175]
[71]
Rubinstein RY,Rosen A,Leeman D, Frey syndrome: treatment with temporoparietal fascia flap interposition. Archives of otolaryngology--head & neck surgery. 1999 Jul
[PubMed PMID: 10406323]
[72]
Torretta S,Pignataro L,Capaccio P,Brevi A,Mazzola R, Fat injections for the management of post-parotidectomy Frey syndrome: a technical note. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 2012 Feb
[PubMed PMID: 21458286]
[73]
Adar R,Kurchin A,Zweig A,Mozes M, Palmar hyperhidrosis and its surgical treatment: a report of 100 cases. Annals of surgery. 1977 Jul;
[PubMed PMID: 879872]
Level 3 (low-level) evidence
[75]
Hornberger J,Grimes K,Naumann M,Glaser DA,Lowe NJ,Naver H,Ahn S,Stolman LP, Recognition, diagnosis, and treatment of primary focal hyperhidrosis. Journal of the American Academy of Dermatology. 2004 Aug;
[PubMed PMID: 15280848]
[76]
Lakraj AA,Moghimi N,Jabbari B, Hyperhidrosis: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins. Toxins. 2013 Apr 23;
[PubMed PMID: 23612753]
[77]
Montoya FJ,Riddell CE,Caesar R,Hague S, Treatment of gustatory hyperlacrimation (crocodile tears) with injection of botulinum toxin into the lacrimal gland. Eye (London, England). 2002 Nov;
[PubMed PMID: 12439663]
[78]
de Oliveira D,Gomes-Ferreira PH,Carrasco LC,de Deus CB,Garcia-Júnior IR,Faverani LP, The Importance of Correct Diagnosis of Crocodile Tears Syndrome. The Journal of craniofacial surgery. 2016 Oct;
[PubMed PMID: 27536922]
[79]
Boddie AW,Guillamondegui OM,Byers RM, Gustatory rhinorrhea developing after radical parotidectomy-a new syndrome? Archives of otolaryngology (Chicago, Ill. : 1960). 1976 Apr;
[PubMed PMID: 1267711]
[80]
Gunter AE, Llewellyn CM, Perez PB, Hohman MH, Roofe SB. First Bite Syndrome Following Rhytidectomy: A Case Report. The Annals of otology, rhinology, and laryngology. 2021 Jan:130(1):92-97. doi: 10.1177/0003489420936713. Epub 2020 Jun 21
[PubMed PMID: 32567395]
Level 3 (low-level) evidence
[81]
Linkov G,Morris LG,Shah JP,Kraus DH, First bite syndrome: incidence, risk factors, treatment, and outcomes. The Laryngoscope. 2012 Aug;
[PubMed PMID: 22573579]
[82]
Charles-Harris H,Rodriguez B, First Bite Syndrome: Presentation of a Patient Status-Post Right Carotid Endarterectomy. Vascular and endovascular surgery. 2021 Jan;
[PubMed PMID: 32862800]
[83]
Gualberto GV,Sampaio FMS,Madureira NAB, Use of botulinum toxin type A in Frey's syndrome. Anais brasileiros de dermatologia. 2017 Nov-Dec;
[PubMed PMID: 29364460]
[85]
Baek CH,Chung MK,Jeong HS,Son YI,Jung SC,Jeon HK,Ryu NG,Cho HJ,Cho JK,Jang JY, Questionnaire evaluation of sequelae over 5 years after parotidectomy for benign diseases. Journal of plastic, reconstructive
[PubMed PMID: 18314403]
[86]
Gunsoy B,Vuralkan E,Sonbay ND,Simsek G,Tokgoz SA,Akin I, Quality of life following surgical treatment of benign parotid disease. Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India. 2013 Jul;
[PubMed PMID: 24427625]
Level 2 (mid-level) evidence