Neurodevelopmental Disabilities CME

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About StatPearls CME

All of our activities are approved by AMA PRA Category 1 (MD or PA) and all activity is reported to CE Broker and all states as required. StatPearls continuing education activities are linked to practice questions which are based on the American Board of Psychiatry and Neurology® and American Osteopathic Board of Neurology and Psychiatry® content outlines. 144 authors and 5 editors have contributed to the development of the Neurodevelopmental Disabilities content, which is continuously refined and updated to improve your learning experience.

Neurodevelopmental Disabilities Activities

Title Description Hours Questions
Abnormal Neonatal EEG Electroencephalogram of a newborn shows unique features compared to older children and adults. The principles employed in the identification of abnorm ... Read the Article 1 5 Activity DO
Abnormal Neonatal EEG Electroencephalogram of a newborn shows unique features compared to older children and adults. The principles employed in the identification of abnorm ... Read the Article 1 5 Activity MD/PA
Adrenoleukodystrophy Adrenoleukodystrophy is a peroxisomal disorder resulting from abnormal metabolism of the very-long-chain fatty acids (VLCFA). It is classified into di ... Read the Article 1.25 13 Activity DO
Adrenoleukodystrophy Adrenoleukodystrophy is a peroxisomal disorder resulting from abnormal metabolism of the very-long-chain fatty acids (VLCFA). It is classified into di ... Read the Article 1.25 13 Activity MD/PA
Alexander Disease Alexander disease is a relatively rare leukodystrophy that generally presents in the infantile period, although other variants are occasionally seen. ... Read the Article 1 5 Activity DO
Alexander Disease Alexander disease is a relatively rare leukodystrophy that generally presents in the infantile period, although other variants are occasionally seen. ... Read the Article 1 5 Activity MD/PA
Angelman Syndrome Angelman syndrome is a rare disorder caused by loss of function of the maternal UBE3A. It presents in childhood with psychomotor delay, absent speech, ... Read the Article 1 6 Activity DO
Angelman Syndrome Angelman syndrome is a rare disorder caused by loss of function of the maternal UBE3A. It presents in childhood with psychomotor delay, absent speech, ... Read the Article 1 6 Activity MD/PA
Aplasia Cutis Congenita Aplasia cutis congenita (ACC) is a rare congenital skin defect characterized by a focal or extensive absence of the epidermis, dermis, and occasionall ... Read the Article 1 5 Activity DO
Aplasia Cutis Congenita Aplasia cutis congenita (ACC) is a rare congenital skin defect characterized by a focal or extensive absence of the epidermis, dermis, and occasionall ... Read the Article 1 5 Activity MD/PA
Arginase Deficiency Argininemia is an autosomal recessive disorder causing hyperammonemia secondary to arginine accumulation. It is a disorder first noticed in children w ... Read the Article 1 6 Activity DO
Arginase Deficiency Argininemia is an autosomal recessive disorder causing hyperammonemia secondary to arginine accumulation. It is a disorder first noticed in children w ... Read the Article 1 6 Activity MD/PA
Arnold Chiari Malformation Arnold-Chiari or Chiari malformations describe a group of deformities of the posterior fossa and hindbrain, which includes the cerebellum, pons, and m ... Read the Article 1.25 9 Activity DO
Arnold Chiari Malformation Arnold-Chiari or Chiari malformations describe a group of deformities of the posterior fossa and hindbrain, which includes the cerebellum, pons, and m ... Read the Article 1.25 9 Activity MD/PA
Asperger Syndrome Asperger syndrome is a neurodevelopmental disorder within the large family of autism spectrum disorder. It is characterized by impaired social communi ... Read the Article 1.25 5 Activity DO
Asperger Syndrome Asperger syndrome is a neurodevelopmental disorder within the large family of autism spectrum disorder. It is characterized by impaired social communi ... Read the Article 1.25 5 Activity MD/PA
Ataxia Ataxia is a neurological sign that manifests in a lack of coordination in the movement of different muscles in the body. It is a clinical finding and ... Read the Article 1 5 Activity DO
Ataxia Ataxia is a neurological sign that manifests in a lack of coordination in the movement of different muscles in the body. It is a clinical finding and ... Read the Article 1 5 Activity MD/PA
Ataxia Telangiectasia Ataxia telangiectasia (Louis-Bar Syndrome) is a rare autosomal recessive condition characterized by cutaneous telangiectasias, cerebellar atrophy with ... Read the Article 1.25 13 Activity DO
Ataxia Telangiectasia Ataxia telangiectasia (Louis-Bar Syndrome) is a rare autosomal recessive condition characterized by cutaneous telangiectasias, cerebellar atrophy with ... Read the Article 1.25 13 Activity MD/PA
Athetoid Cerebral Palsy Athetoid cerebral palsy, also known as dyskinetic cerebral palsy, is the second most common subtype of cerebral palsy. It is a non-progressive, perman ... Read the Article 1 5 Activity DO
Athetoid Cerebral Palsy Athetoid cerebral palsy, also known as dyskinetic cerebral palsy, is the second most common subtype of cerebral palsy. It is a non-progressive, perman ... Read the Article 1 5 Activity MD/PA
Atlantoaxial Instability The atlantoaxial segment consists of the atlas (C1) and axis (C2) and forms a complex transitional structure bridging the occiput and cervical spine. ... Read the Article 1.25 9 Activity DO
Atlantoaxial Instability The atlantoaxial segment consists of the atlas (C1) and axis (C2) and forms a complex transitional structure bridging the occiput and cervical spine. ... Read the Article 1.25 9 Activity MD/PA
Attention Deficit Hyperactivity Disorder The diagnosis of attention deficit hyperactivity disorder (ADHD) has been surrounded by controversy over the last century. Over the past 30 years, how ... Read the Article 1.5 15 Activity DO
Attention Deficit Hyperactivity Disorder The diagnosis of attention deficit hyperactivity disorder (ADHD) has been surrounded by controversy over the last century. Over the past 30 years, how ... Read the Article 1.5 15 Activity MD/PA
Autism Spectrum Disorder Autism spectrum disorders (ASD) are a group of rapidly growing disabilities. They are characterized by repetitive patterns of behavior, interests, or ... Read the Article 1.75 21 Activity DO
Autism Spectrum Disorder Autism spectrum disorders (ASD) are a group of rapidly growing disabilities. They are characterized by repetitive patterns of behavior, interests, or ... Read the Article 1.75 21 Activity MD/PA
Basilar Invagination Basilar invagination is an abnormality at the craniovertebral junction, either congenital or degenerative, resulting in the odontoid prolapsing into t ... Read the Article 1.25 8 Activity DO
Basilar Invagination Basilar invagination is an abnormality at the craniovertebral junction, either congenital or degenerative, resulting in the odontoid prolapsing into t ... Read the Article 1.25 8 Activity MD/PA
Benign Occipital Seizure Benign occipital seizures are classified as an occipital onset epilepsy syndrome, which occurs in children with normal developmental milestones, norma ... Read the Article 1 6 Activity DO
Benign Occipital Seizure Benign occipital seizures are classified as an occipital onset epilepsy syndrome, which occurs in children with normal developmental milestones, norma ... Read the Article 1 6 Activity MD/PA
Biotin Deficiency Biotin is a B-complex vitamin that serves as an essential coenzyme for five carboxylases: pyruvate carboxylase, 3-methylcrotonyl-CoA carboxylase, prop ... Read the Article 1 6 Activity DO
Biotin Deficiency Biotin is a B-complex vitamin that serves as an essential coenzyme for five carboxylases: pyruvate carboxylase, 3-methylcrotonyl-CoA carboxylase, prop ... Read the Article 1 6 Activity MD/PA
Biotinidase Deficiency Biotin acts as a coenzyme for four carboxylation enzymes in the body: 3-methylcrontonyl-CoA carboxylase (MCC), pyruvate carboxylase (PC), acetyl-CoA c ... Read the Article 1 4 Activity DO
Biotinidase Deficiency Biotin acts as a coenzyme for four carboxylation enzymes in the body: 3-methylcrontonyl-CoA carboxylase (MCC), pyruvate carboxylase (PC), acetyl-CoA c ... Read the Article 1 4 Activity MD/PA
Bloom Syndrome Bloom syndrome, also called Bloom-Torre-Machacek syndrome or congenital telangiectatic erythema, is a rare autosomal recessive inherited disorder char ... Read the Article 1 5 Activity DO
Bloom Syndrome Bloom syndrome, also called Bloom-Torre-Machacek syndrome or congenital telangiectatic erythema, is a rare autosomal recessive inherited disorder char ... Read the Article 1 5 Activity MD/PA
Brain Cavernous Angiomas Cavernous angiomas, also referred to as cavernous malformations (CMs), cavernous hemangiomas, or cavernomas are benign intracranial vascular malformat ... Read the Article 1 5 Activity DO
Brain Cavernous Angiomas Cavernous angiomas, also referred to as cavernous malformations (CMs), cavernous hemangiomas, or cavernomas are benign intracranial vascular malformat ... Read the Article 1 5 Activity MD/PA
Cafe Au Lait Macules Cafe-au-lait macules (CALMs) are common pigmented lesions found in the general population. They can be described as well-circumscribed, pigmented macu ... Read the Article 1.25 8 Activity DO
Cafe Au Lait Macules Cafe-au-lait macules (CALMs) are common pigmented lesions found in the general population. They can be described as well-circumscribed, pigmented macu ... Read the Article 1.25 8 Activity MD/PA
Cavum Septum Pellucidum The septum pellucidum (meaning translucent wall in Latin - SP), also known as the ventricle of Sylvius, is a thin, triangular double membrane separati ... Read the Article 1 5 Activity DO
Cavum Septum Pellucidum The septum pellucidum (meaning translucent wall in Latin - SP), also known as the ventricle of Sylvius, is a thin, triangular double membrane separati ... Read the Article 1 5 Activity MD/PA
Cavum Veli Interpositi The velum interpositum (VI) is a membrane resulting from the superposition of two layers of the tela choroidea of the third ventricle demarcating a po ... Read the Article 1 4 Activity DO
Cavum Veli Interpositi The velum interpositum (VI) is a membrane resulting from the superposition of two layers of the tela choroidea of the third ventricle demarcating a po ... Read the Article 1 4 Activity MD/PA
Cerebral Cavernous Malformations A cerebral cavernous malformation (CCM) is an abnormally large collection of "low flow" vascular channels without brain parenchyma intervening between ... Read the Article 1 5 Activity DO
Cerebral Cavernous Malformations A cerebral cavernous malformation (CCM) is an abnormally large collection of "low flow" vascular channels without brain parenchyma intervening between ... Read the Article 1 5 Activity MD/PA
Cerebral Palsy Cerebral palsy is a group of permanent disorders affecting the development of movement and causing a limitation of activity. Non-progressive disturban ... Read the Article 1.25 11 Activity DO
Cerebral Palsy Cerebral palsy is a group of permanent disorders affecting the development of movement and causing a limitation of activity. Non-progressive disturban ... Read the Article 1.25 11 Activity MD/PA
Cerebrotendinous Xanthomatosis Cerebrotendinous xanthomatosis is a rare autosomal recessive lipid storage disease associated with abnormally high cholestanol levels in the blood, ac ... Read the Article 1 5 Activity DO
Cerebrotendinous Xanthomatosis Cerebrotendinous xanthomatosis is a rare autosomal recessive lipid storage disease associated with abnormally high cholestanol levels in the blood, ac ... Read the Article 1 5 Activity MD/PA
Charcot Marie Tooth Charcot-Marie-Tooth disease (CMT) is the commonest inherited neuromuscular disorder. It affects the peripheral nerves and leads to progressive weaknes ... Read the Article 1.75 18 Activity DO
Charcot Marie Tooth Charcot-Marie-Tooth disease (CMT) is the commonest inherited neuromuscular disorder. It affects the peripheral nerves and leads to progressive weaknes ... Read the Article 1.75 18 Activity MD/PA
Cherry Red Spot A cherry-red spot refers to a red-tinted region at the center of macula surrounded by retinal opacification. Cherry-red spots may be present in a vari ... Read the Article 1 5 Activity DO
Cherry Red Spot A cherry-red spot refers to a red-tinted region at the center of macula surrounded by retinal opacification. Cherry-red spots may be present in a vari ... Read the Article 1 5 Activity MD/PA
Chiari I Malformation Arnold-Chiari 1 malformation, otherwise known as the Chiari 1 malformation, is the more common variant of the Chiari malformations, defined as a spect ... Read the Article 1.25 8 Activity DO
Chiari I Malformation Arnold-Chiari 1 malformation, otherwise known as the Chiari 1 malformation, is the more common variant of the Chiari malformations, defined as a spect ... Read the Article 1.25 8 Activity MD/PA
Chiari II Malformation Chiari II malformation is a relatively common congenital malformation of the posterior fossa and the spine characterized by beaked midbrain, downward ... Read the Article 1 6 Activity DO
Chiari II Malformation Chiari II malformation is a relatively common congenital malformation of the posterior fossa and the spine characterized by beaked midbrain, downward ... Read the Article 1 6 Activity MD/PA
Child Development The stages through which a child goes through from birth until he or she becomes an adult is child development. Children are first newborns, and durin ... Read the Article 3.25 60 Activity DO
Child Development The stages through which a child goes through from birth until he or she becomes an adult is child development. Children are first newborns, and durin ... Read the Article 3.25 60 Activity MD/PA
Childhood Brain Tumors Pediatric brain tumors are the most common type of solid childhood cancer and only second to leukemia as a cause of pediatric malignancies. They are c ... Read the Article 1 7 Activity DO
Childhood Brain Tumors Pediatric brain tumors are the most common type of solid childhood cancer and only second to leukemia as a cause of pediatric malignancies. They are c ... Read the Article 1 7 Activity MD/PA
Congenital Myotonic Dystrophy Congenital myotonic dystrophy (CMD) is an autosomal dominant neuromuscular disorder with multisystem involvement. It is a subtype of myotonic dystroph ... Read the Article 1.25 10 Activity DO
Congenital Myotonic Dystrophy Congenital myotonic dystrophy (CMD) is an autosomal dominant neuromuscular disorder with multisystem involvement. It is a subtype of myotonic dystroph ... Read the Article 1.25 10 Activity MD/PA
Cornelia de Lange Syndrome Cornelia de Lange syndrome (CdLS) was initially described in 1933. CdLS is a genetic disorder that affects many organs, leading to various clinical pr ... Read the Article 1 6 Activity DO
Cornelia de Lange Syndrome Cornelia de Lange syndrome (CdLS) was initially described in 1933. CdLS is a genetic disorder that affects many organs, leading to various clinical pr ... Read the Article 1 6 Activity MD/PA
Cowden Disease Cowden disease, also known as Cowden syndrome or multiple hamartoma syndrome, is an uncommon autosomal dominant genodermatosis and is a member of the ... Read the Article 1.25 10 Activity DO
Cowden Disease Cowden disease, also known as Cowden syndrome or multiple hamartoma syndrome, is an uncommon autosomal dominant genodermatosis and is a member of the ... Read the Article 1.25 10 Activity MD/PA
Dandy Walker Malformation Dandy-Walker malformation (DWM) or syndrome is a posterior fossa anomaly characterized by agenesis or hypoplasia of the vermis and cystic enlargement ... Read the Article 1 5 Activity DO
Dandy Walker Malformation Dandy-Walker malformation (DWM) or syndrome is a posterior fossa anomaly characterized by agenesis or hypoplasia of the vermis and cystic enlargement ... Read the Article 1 5 Activity MD/PA
Dentatorubral Pallidoluysian Atrophy Dentatorubral-pallidoluysian atrophy (DRPLA) is a progressive, autosomal dominant disorder with symptoms and severity that vary with the age of onset. ... Read the Article 1 5 Activity DO
Dentatorubral Pallidoluysian Atrophy Dentatorubral-pallidoluysian atrophy (DRPLA) is a progressive, autosomal dominant disorder with symptoms and severity that vary with the age of onset. ... Read the Article 1 5 Activity MD/PA
Developmental Delay Delay in development occurs when the child fails to attain developmental milestones as compared to peers from the same population. It is caused by imp ... Read the Article 1.25 11 Activity DO
Developmental Delay Delay in development occurs when the child fails to attain developmental milestones as compared to peers from the same population. It is caused by imp ... Read the Article 1.25 11 Activity MD/PA
Down Syndrome Down syndrome (trisomy 21) is a genetic disorder caused by the presence of all or a portion of a third chromosome 21. Patients typically present with ... Read the Article 1.25 8 Activity DO
Down Syndrome Down syndrome (trisomy 21) is a genetic disorder caused by the presence of all or a portion of a third chromosome 21. Patients typically present with ... Read the Article 1.25 8 Activity MD/PA
Duchenne Muscular Dystrophy Unfortunately, Duchenne muscular dystrophy (DMD) is not only one of the most severe forms of inherited muscular dystrophies but also the most common h ... Read the Article 1.75 22 Activity DO
Duchenne Muscular Dystrophy Unfortunately, Duchenne muscular dystrophy (DMD) is not only one of the most severe forms of inherited muscular dystrophies but also the most common h ... Read the Article 1.75 22 Activity MD/PA
Dystonia Dystonia is defined by involuntary maintained contraction of agonist and antagonist muscles yielding abnormal posturing, twisting and repetitive movem ... Read the Article 1 6 Activity DO
Dystonia Dystonia is defined by involuntary maintained contraction of agonist and antagonist muscles yielding abnormal posturing, twisting and repetitive movem ... Read the Article 1 6 Activity MD/PA
EEG Neonatal Visual Analysis An electroencephalogram (EEG) is a useful ancillary and diagnostic test that detects electrical activity in the brain. The neonatal EEG can be quite c ... Read the Article 1 4 Activity DO
EEG Neonatal Visual Analysis An electroencephalogram (EEG) is a useful ancillary and diagnostic test that detects electrical activity in the brain. The neonatal EEG can be quite c ... Read the Article 1 4 Activity MD/PA
Electrical Status Epilepticus In Sleep Electrical status epilepticus in sleep (ESES), a childhood-onset epileptic encephalopathy, is characterized by epilepsy, cognitive regression, and mar ... Read the Article 1 5 Activity DO
Electrical Status Epilepticus In Sleep Electrical status epilepticus in sleep (ESES), a childhood-onset epileptic encephalopathy, is characterized by epilepsy, cognitive regression, and mar ... Read the Article 1 5 Activity MD/PA
Encephalocele Encephalocele is usually a congenital type of neural tube defect, where a sac containing brain/meninges/cerebrospinal fluid forms outside the skull du ... Read the Article 1 5 Activity DO
Encephalocele Encephalocele is usually a congenital type of neural tube defect, where a sac containing brain/meninges/cerebrospinal fluid forms outside the skull du ... Read the Article 1 5 Activity MD/PA
Fragile X Syndrome Fragile X syndrome (FXS), also called Martin-Bell syndrome, is a non-Mendelian trinucleotide repeat disorder. FXS is the most prevalent inherited caus ... Read the Article 1 8 Activity DO
Fragile X Syndrome Fragile X syndrome (FXS), also called Martin-Bell syndrome, is a non-Mendelian trinucleotide repeat disorder. FXS is the most prevalent inherited caus ... Read the Article 1 8 Activity MD/PA
Gerstmann Syndrome Gerstmann syndrome is a rare neurological disorder consisting of a tetrad of symptoms which include impairment in performing calculations (acalculia), ... Read the Article 1 5 Activity DO
Gerstmann Syndrome Gerstmann syndrome is a rare neurological disorder consisting of a tetrad of symptoms which include impairment in performing calculations (acalculia), ... Read the Article 1 5 Activity MD/PA
Hallervorden Spatz Disease Hallervorden-Spatz disease now known as pantothenate kinase-associated neurodegeneration (PKAN) is a rare autosomal recessive neurodegenerative disord ... Read the Article 1 5 Activity DO
Hallervorden Spatz Disease Hallervorden-Spatz disease now known as pantothenate kinase-associated neurodegeneration (PKAN) is a rare autosomal recessive neurodegenerative disord ... Read the Article 1 5 Activity MD/PA
Holoprosencephaly Holoprosencephaly occurs as a result of anomalous signaling interactions between the neural crest and neural ectoderm. This primarily results in the a ... Read the Article 1 6 Activity DO
Holoprosencephaly Holoprosencephaly occurs as a result of anomalous signaling interactions between the neural crest and neural ectoderm. This primarily results in the a ... Read the Article 1 6 Activity MD/PA
Hurler Syndrome Hurler syndrome, also known as mucopolysaccharidosis type I (MPH I), is one of the eleven mucopolysaccharidoses (MPS) disorders. Hurler syndrome was f ... Read the Article 1 4 Activity DO
Hurler Syndrome Hurler syndrome, also known as mucopolysaccharidosis type I (MPH I), is one of the eleven mucopolysaccharidoses (MPS) disorders. Hurler syndrome was f ... Read the Article 1 4 Activity MD/PA
Hydranencephaly Hydranencephaly is a rare congenital abnormality in which the cerebral hemispheres are absent with the basal ganglia, brainstem and meninges preserved ... Read the Article 1 5 Activity DO
Hydranencephaly Hydranencephaly is a rare congenital abnormality in which the cerebral hemispheres are absent with the basal ganglia, brainstem and meninges preserved ... Read the Article 1 5 Activity MD/PA
Hypokalemic Periodic Paralysis Hypokalemic periodic paralysis is a rare channelopathy caused by the skeletal muscle ion channel mutations, commonly calcium channel and less commonly ... Read the Article 1.25 7 Activity DO
Hypokalemic Periodic Paralysis Hypokalemic periodic paralysis is a rare channelopathy caused by the skeletal muscle ion channel mutations, commonly calcium channel and less commonly ... Read the Article 1.25 7 Activity MD/PA
Hypothalamic Hamartoma Hypothalamic hamartomas are congenital non-progressive lesions in the hypothalamus. These lesions usually develop a disabling course presenting with m ... Read the Article 1 4 Activity DO
Hypothalamic Hamartoma Hypothalamic hamartomas are congenital non-progressive lesions in the hypothalamus. These lesions usually develop a disabling course presenting with m ... Read the Article 1 4 Activity MD/PA
Hypotonia Hypotonia is an easily recognizable entity but determining the etiology is a challenging task for a clinician given its vast differential. Systematica ... Read the Article 1.25 10 Activity DO
Hypotonia Hypotonia is an easily recognizable entity but determining the etiology is a challenging task for a clinician given its vast differential. Systematica ... Read the Article 1.25 10 Activity MD/PA
Inborn Errors Of Metabolism Inborn errors of metabolism are a heterogeneous group of disorders that may be inherited or may occur as the result of spontaneous mutations. These di ... Read the Article 1 7 Activity DO
Inborn Errors Of Metabolism Inborn errors of metabolism are a heterogeneous group of disorders that may be inherited or may occur as the result of spontaneous mutations. These di ... Read the Article 1 7 Activity MD/PA
Infantile Spasm Infantile spasms are spasms that occur in infancy or early childhood. They are classically characterized by symmetric, brief jerking spells that invol ... Read the Article 1 5 Activity DO
Infantile Spasm Infantile spasms are spasms that occur in infancy or early childhood. They are classically characterized by symmetric, brief jerking spells that invol ... Read the Article 1 5 Activity MD/PA
Intellectual Disability Individuals with an intellectual disability have neurodevelopmental deficits characterized by limitations in intellectual functioning and adaptive beh ... Read the Article 1.75 19 Activity DO
Intellectual Disability Individuals with an intellectual disability have neurodevelopmental deficits characterized by limitations in intellectual functioning and adaptive beh ... Read the Article 1.75 19 Activity MD/PA
Juvenile Absence Epilepsy Juvenile absence epilepsy is an idiopathic generalized epilepsy syndrome that is recognized by the ILAE (International League Against Epilepsy) that t ... Read the Article 1 7 Activity DO
Juvenile Absence Epilepsy Juvenile absence epilepsy is an idiopathic generalized epilepsy syndrome that is recognized by the ILAE (International League Against Epilepsy) that t ... Read the Article 1 7 Activity MD/PA
Juvenile Myoclonic Epilepsy Juvenile myoclonic epilepsy (JME), otherwise known as Janz syndrome and impulsive petit mal, is an idiopathic, hereditary, and generalized form of epi ... Read the Article 1 4 Activity DO
Juvenile Myoclonic Epilepsy Juvenile myoclonic epilepsy (JME), otherwise known as Janz syndrome and impulsive petit mal, is an idiopathic, hereditary, and generalized form of epi ... Read the Article 1 4 Activity MD/PA
Kayser-Fleischer Ring Kayser–Fleischer (KF) rings are a common ophthalmologic finding in patients with Wilson disease. Initially thought to be due to the accumulation of si ... Read the Article 1 5 Activity DO
Kayser-Fleischer Ring Kayser–Fleischer (KF) rings are a common ophthalmologic finding in patients with Wilson disease. Initially thought to be due to the accumulation of si ... Read the Article 1 5 Activity MD/PA
Klippel Feil Syndrome Klippel-Feil syndrome presents with an abnormal fusion of 2 or more bones in the cervical spine. This creates a characteristic appearance of a short n ... Read the Article 1 4 Activity DO
Klippel Feil Syndrome Klippel-Feil syndrome presents with an abnormal fusion of 2 or more bones in the cervical spine. This creates a characteristic appearance of a short n ... Read the Article 1 4 Activity MD/PA
Krabbe Disease Krabbe disease, an autosomal recessive disease, is a type of lysosomal storage disorder that results from the deficiency of the enzyme galactocerebros ... Read the Article 1 4 Activity DO
Krabbe Disease Krabbe disease, an autosomal recessive disease, is a type of lysosomal storage disorder that results from the deficiency of the enzyme galactocerebros ... Read the Article 1 4 Activity MD/PA
Lafora Disease Lafora disease is a type of progressive myoclonic epilepsy that is inherited in an autosomal recessive manner and typically presents in previously hea ... Read the Article 1 5 Activity DO
Lafora Disease Lafora disease is a type of progressive myoclonic epilepsy that is inherited in an autosomal recessive manner and typically presents in previously hea ... Read the Article 1 5 Activity MD/PA
Landau Kleffner Syndrome Landau-Kleffner syndrome is a rare age-related epileptic encephalopathy that usually manifests itself in children aged 3 to 8 years with previously no ... Read the Article 1 5 Activity DO
Landau Kleffner Syndrome Landau-Kleffner syndrome is a rare age-related epileptic encephalopathy that usually manifests itself in children aged 3 to 8 years with previously no ... Read the Article 1 5 Activity MD/PA
Learning Disability Learning disabilities (LDs) refer to a number of disorders that may affect the acquisition, organization, retention, comprehension, or the use of both ... Read the Article 1.25 9 Activity DO
Learning Disability Learning disabilities (LDs) refer to a number of disorders that may affect the acquisition, organization, retention, comprehension, or the use of both ... Read the Article 1.25 9 Activity MD/PA
Lennox Gastaut Syndrome Lennox-Gastaut syndrome (LGS) is a rare but severe form of childhood epilepsy. LGS is characterized by a triad of multiple seizure types, characterist ... Read the Article 1 5 Activity DO
Lennox Gastaut Syndrome Lennox-Gastaut syndrome (LGS) is a rare but severe form of childhood epilepsy. LGS is characterized by a triad of multiple seizure types, characterist ... Read the Article 1 5 Activity MD/PA
Lesch Nyhan Syndrome Lesch Nyhan Syndrome is an inborn disorder caused by a deficiency of hypoxanthine-guanine phosphoribosyltransferase (HPRT) enzyme, an enzyme of purine ... Read the Article 1.25 9 Activity DO
Lesch Nyhan Syndrome Lesch Nyhan Syndrome is an inborn disorder caused by a deficiency of hypoxanthine-guanine phosphoribosyltransferase (HPRT) enzyme, an enzyme of purine ... Read the Article 1.25 9 Activity MD/PA
Lisch Nodules Lisch nodules, traditionally described as iris hamartomas is one of the pathognomic markers of neurofibromatosis type 1 (NF1) and are rarely seen in i ... Read the Article 1 7 Activity DO
Lisch Nodules Lisch nodules, traditionally described as iris hamartomas is one of the pathognomic markers of neurofibromatosis type 1 (NF1) and are rarely seen in i ... Read the Article 1 7 Activity MD/PA
Melas Syndrome Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) is a mitochondrial disease primarily affecting the nervous system an ... Read the Article 1 6 Activity DO
Melas Syndrome Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) is a mitochondrial disease primarily affecting the nervous system an ... Read the Article 1 6 Activity MD/PA
Meningocele Meningocele is one of the common congenital neural tube defects. Meningocele is the simplest form of open neural tube defects characterized by cystic ... Read the Article 1.25 10 Activity DO
Meningocele Meningocele is one of the common congenital neural tube defects. Meningocele is the simplest form of open neural tube defects characterized by cystic ... Read the Article 1.25 10 Activity MD/PA
Menkes Kinky Hair Disease Menkes kinky hair disease is a rare X-linked recessive progressive multisystemic disease of copper metabolism. Patients usually exhibit a severe clini ... Read the Article 1 6 Activity DO
Menkes Kinky Hair Disease Menkes kinky hair disease is a rare X-linked recessive progressive multisystemic disease of copper metabolism. Patients usually exhibit a severe clini ... Read the Article 1 6 Activity MD/PA
Metachromatic Leukodystrophy Metachromatic leukodystrophy is a rare lysosomal storage disease caused due to deficient activity of arylsulfatase A. It follows an autosomal recessiv ... Read the Article 1 5 Activity DO
Metachromatic Leukodystrophy Metachromatic leukodystrophy is a rare lysosomal storage disease caused due to deficient activity of arylsulfatase A. It follows an autosomal recessiv ... Read the Article 1 5 Activity MD/PA
Mucopolysaccharidosis Type II Mucopolysaccharidosis Type II (Hunter syndrome) is a rare X-linked recessive disorder. It has an early age of onset with clinical symptoms involving m ... Read the Article 1.25 7 Activity DO
Mucopolysaccharidosis Type II Mucopolysaccharidosis Type II (Hunter syndrome) is a rare X-linked recessive disorder. It has an early age of onset with clinical symptoms involving m ... Read the Article 1.25 7 Activity MD/PA
Multiple Endocrine Neoplasia Type 1 Multiple endocrine neoplasia Type 1 (MEN1), also known as Wermer syndrome, is a rare hereditary endocrine tumor syndrome. The most common tumors seen ... Read the Article 1.25 7 Activity DO
Multiple Endocrine Neoplasia Type 1 Multiple endocrine neoplasia Type 1 (MEN1), also known as Wermer syndrome, is a rare hereditary endocrine tumor syndrome. The most common tumors seen ... Read the Article 1.25 7 Activity MD/PA
Muscular Dystrophy The term "muscular dystrophy" incorporates an assortment of hereditary disorders that lead to progressive, generalized disease of the muscle prompted ... Read the Article 1.25 6 Activity DO
Muscular Dystrophy The term "muscular dystrophy" incorporates an assortment of hereditary disorders that lead to progressive, generalized disease of the muscle prompted ... Read the Article 1.25 6 Activity MD/PA
Myotonic Dystrophy Myotonic dystrophy is a rare progressive disorder that universally presents with weakness. In addition to musculoskeletal weakness, cardiac conduction ... Read the Article 1.25 10 Activity DO
Myotonic Dystrophy Myotonic dystrophy is a rare progressive disorder that universally presents with weakness. In addition to musculoskeletal weakness, cardiac conduction ... Read the Article 1.25 10 Activity MD/PA
Neonatal EEG Neurological evaluation of the neonate has many inherent limitations that make it challenging to delineate physiological variations from pathological ... Read the Article 1 4 Activity DO
Neonatal EEG Neurological evaluation of the neonate has many inherent limitations that make it challenging to delineate physiological variations from pathological ... Read the Article 1 4 Activity MD/PA
Neural Tube Disorders Neural tube defects are the most common severe central nervous system anomalies, only second to cardiovascular abnormalities resulting in congenital m ... Read the Article 1.25 12 Activity DO
Neural Tube Disorders Neural tube defects are the most common severe central nervous system anomalies, only second to cardiovascular abnormalities resulting in congenital m ... Read the Article 1.25 12 Activity MD/PA
Neuroacanthocytosis Neuroacanthocytosis refers to a group of inherited genetic disorders resulting in a combination of misshapen red blood cells (acanthocytes) and progre ... Read the Article 1 5 Activity DO
Neuroacanthocytosis Neuroacanthocytosis refers to a group of inherited genetic disorders resulting in a combination of misshapen red blood cells (acanthocytes) and progre ... Read the Article 1 5 Activity MD/PA
Neurocutaneous Syndromes As the name implies, neurocutaneous syndromes are disorders involving the nervous system and the skin. Two of the most common neurocutaneous syndrome ... Read the Article 1 4 Activity DO
Neurocutaneous Syndromes As the name implies, neurocutaneous syndromes are disorders involving the nervous system and the skin. Two of the most common neurocutaneous syndrome ... Read the Article 1 4 Activity MD/PA
Neurofibroma Neurofibromas are the most common peripheral nerve sheath tumor and are often found either by patients or during routine skin exams. These lesions app ... Read the Article 1.25 8 Activity DO
Neurofibroma Neurofibromas are the most common peripheral nerve sheath tumor and are often found either by patients or during routine skin exams. These lesions app ... Read the Article 1.25 8 Activity MD/PA
Neurofibromatosis Neurofibromatosis is a neurocutaneous disorder characterized by tumors in the nervous system and skin. The most common types of neurofibromatosis are ... Read the Article 1.25 9 Activity DO
Neurofibromatosis Neurofibromatosis is a neurocutaneous disorder characterized by tumors in the nervous system and skin. The most common types of neurofibromatosis are ... Read the Article 1.25 9 Activity MD/PA
Neurofibromatosis Type 1 Neurofibromatosis-1 (NF-1) or Von Recklinghausen's disease is one of the inheritable neurocutaneous disorders manifested by developmental changes in t ... Read the Article 1 7 Activity DO
Neurofibromatosis Type 1 Neurofibromatosis-1 (NF-1) or Von Recklinghausen's disease is one of the inheritable neurocutaneous disorders manifested by developmental changes in t ... Read the Article 1 7 Activity MD/PA
Nevus Flammeus Nevus flammeus or port-wine stain is a capillary malformation usually presenting as a unilateral pink or red patch anywhere on the body of a newborn. ... Read the Article 1.25 7 Activity DO
Nevus Flammeus Nevus flammeus or port-wine stain is a capillary malformation usually presenting as a unilateral pink or red patch anywhere on the body of a newborn. ... Read the Article 1.25 7 Activity MD/PA
Nonketotic Hyperglycinemia Nonketotic hyperglycinemia is a rare, genetic, inborn error of glycine metabolism. Due to a mutation in the glycine cleavage enzyme system, the patien ... Read the Article 1 5 Activity DO
Nonketotic Hyperglycinemia Nonketotic hyperglycinemia is a rare, genetic, inborn error of glycine metabolism. Due to a mutation in the glycine cleavage enzyme system, the patien ... Read the Article 1 5 Activity MD/PA
Opisthotonus Opisthotonus is defined as a dramatic abnormal posture due to spastic contraction of the extensor muscles of the neck, trunk, and lower extremities th ... Read the Article 1 4 Activity DO
Opisthotonus Opisthotonus is defined as a dramatic abnormal posture due to spastic contraction of the extensor muscles of the neck, trunk, and lower extremities th ... Read the Article 1 4 Activity MD/PA
Optic Nerve Glioma Optic pathway gliomas are benign CNS tumors that primarily affect children. Although typically slow growing, the location of these tumors makes resect ... Read the Article 1 5 Activity DO
Optic Nerve Glioma Optic pathway gliomas are benign CNS tumors that primarily affect children. Although typically slow growing, the location of these tumors makes resect ... Read the Article 1 5 Activity MD/PA
Pain Assessment There are multiple tools used to help assess a patient's pain. These tools can be used to assess multiple types of pain, ranging from nociceptive pain ... Read the Article 1.25 10 Activity DO
Pain Assessment There are multiple tools used to help assess a patient's pain. These tools can be used to assess multiple types of pain, ranging from nociceptive pain ... Read the Article 1.25 10 Activity MD/PA
Pelizaeus-Merzbacher Disease Pelizaeus-Merzbacher disease (PMD) is a demyelinating disorder of the CNS belonging to the group of hypomyelination leukodystrophies. This activity de ... Read the Article 1 5 Activity DO
Pelizaeus-Merzbacher Disease Pelizaeus-Merzbacher disease (PMD) is a demyelinating disorder of the CNS belonging to the group of hypomyelination leukodystrophies. This activity de ... Read the Article 1 5 Activity MD/PA
PHACE Syndrome Infantile hemangioma is the most prevalent benign tumor of infancy, with an estimated incidence between 4 and 5 percent. Large facial segmental hemang ... Read the Article 1 7 Activity DO
PHACE Syndrome Infantile hemangioma is the most prevalent benign tumor of infancy, with an estimated incidence between 4 and 5 percent. Large facial segmental hemang ... Read the Article 1 7 Activity MD/PA
Phenobarbital Phenobarbital is included in a class of drugs called barbiturates. This drug can be used for anti-seizure management, treatment for status epilepticus ... Read the Article 1.25 13 Activity DO
Phenobarbital Phenobarbital is included in a class of drugs called barbiturates. This drug can be used for anti-seizure management, treatment for status epilepticus ... Read the Article 1.25 13 Activity MD/PA
Plagiocephaly Plagiocephaly is defined as an asymmetric shape of the head due to unilateral flattening. The term flathead can be used as a synonym. Plagiocephaly ca ... Read the Article 1 6 Activity DO
Plagiocephaly Plagiocephaly is defined as an asymmetric shape of the head due to unilateral flattening. The term flathead can be used as a synonym. Plagiocephaly ca ... Read the Article 1 6 Activity MD/PA
Prader-Willi Syndrome Prader Willi syndrome (PWS) is a rare and complex genetic disease. The condition has numerous implications on metabolic, endocrine, and neurologic sys ... Read the Article 1.25 10 Activity DO
Prader-Willi Syndrome Prader Willi syndrome (PWS) is a rare and complex genetic disease. The condition has numerous implications on metabolic, endocrine, and neurologic sys ... Read the Article 1.25 10 Activity MD/PA
Refsum Disease Refsum disease is a rare autosomal recessive disease from the peroxisomal biogenesis spectrum of disorders. Peroxisomes are multiple membrane-bound in ... Read the Article 1 5 Activity DO
Refsum Disease Refsum disease is a rare autosomal recessive disease from the peroxisomal biogenesis spectrum of disorders. Peroxisomes are multiple membrane-bound in ... Read the Article 1 5 Activity MD/PA
Rett Syndrome Rett syndrome (RTT) is a neurodevelopmental disorder that should be considered in a child who demonstrates regression in previously acquired skills af ... Read the Article 1 5 Activity DO
Rett Syndrome Rett syndrome (RTT) is a neurodevelopmental disorder that should be considered in a child who demonstrates regression in previously acquired skills af ... Read the Article 1 5 Activity MD/PA
Schizencephaly Schizencephaly is a rare congenital neuronal migration disorder characterized by cleft lined by the heterotopic gray matter, which connects the surfac ... Read the Article 1 7 Activity DO
Schizencephaly Schizencephaly is a rare congenital neuronal migration disorder characterized by cleft lined by the heterotopic gray matter, which connects the surfac ... Read the Article 1 7 Activity MD/PA
Spina Bifida Spina Bifida is a generalized term for the neurologic condition resulting from the failure of neural tube closure of varying degrees during fetal deve ... Read the Article 1.25 10 Activity DO
Spina Bifida Spina Bifida is a generalized term for the neurologic condition resulting from the failure of neural tube closure of varying degrees during fetal deve ... Read the Article 1.25 10 Activity MD/PA
Spinal Cord Abscess Intramedullary spinal cord abscess (ISCA) is a rare central nervous system infection associated with high mortality and neurological morbidity. A qui ... Read the Article 1 5 Activity DO
Spinal Cord Abscess Intramedullary spinal cord abscess (ISCA) is a rare central nervous system infection associated with high mortality and neurological morbidity. A qui ... Read the Article 1 5 Activity MD/PA
Spinal Dysraphism And Myelomeningocele Spinal dysraphism is a congenital abnormality that results in an abnormal structure in the spine, including the bony structure, the spinal cord, and t ... Read the Article 1 5 Activity DO
Spinal Dysraphism And Myelomeningocele Spinal dysraphism is a congenital abnormality that results in an abnormal structure in the spine, including the bony structure, the spinal cord, and t ... Read the Article 1 5 Activity MD/PA
Spinal Muscle Atrophy Spinal muscular atrophy is an inherited autosomal recessive disease of a varying phenotype that is characterized by progressive muscle weakness, reduc ... Read the Article 1.25 7 Activity DO
Spinal Muscle Atrophy Spinal muscular atrophy is an inherited autosomal recessive disease of a varying phenotype that is characterized by progressive muscle weakness, reduc ... Read the Article 1.25 7 Activity MD/PA
Spinocerebellar Ataxia Ataxia is the absence of voluntary muscle coordination and loss control of movement that affects gait stability, eye movement, and speech. Spinocerebe ... Read the Article 1 6 Activity DO
Spinocerebellar Ataxia Ataxia is the absence of voluntary muscle coordination and loss control of movement that affects gait stability, eye movement, and speech. Spinocerebe ... Read the Article 1 6 Activity MD/PA
Sturge-Weber Syndrome Sturge-Weber syndrome, also known as encephalotrigeminal angiomatosis, is a neurocutaneous disorder characterized by angiomas involving the face, chor ... Read the Article 1.25 11 Activity DO
Sturge-Weber Syndrome Sturge-Weber syndrome, also known as encephalotrigeminal angiomatosis, is a neurocutaneous disorder characterized by angiomas involving the face, chor ... Read the Article 1.25 11 Activity MD/PA
Tay-Sachs Disease Tay Sachs disease is a rare autosomal recessive progressive neurodegenerative disorder. Patients usually exhibit a severe clinical course with death i ... Read the Article 1.5 16 Activity DO
Tay-Sachs Disease Tay Sachs disease is a rare autosomal recessive progressive neurodegenerative disorder. Patients usually exhibit a severe clinical course with death i ... Read the Article 1.5 16 Activity MD/PA
Temper Tantrums Although temper tantrums are a normal part of development in toddlers, they can be distressing for caregivers and families. This activity describes ch ... Read the Article 1 3 Activity DO
Temper Tantrums Although temper tantrums are a normal part of development in toddlers, they can be distressing for caregivers and families. This activity describes ch ... Read the Article 1 3 Activity MD/PA
Tourette Syndrome And Other Tic Disorders Tourette syndrome, also referred to as Tourette disorder, is a common neurodevelopmental disorder affecting up to 1 percent of the population. It is c ... Read the Article 1.75 20 Activity DO
Tourette Syndrome And Other Tic Disorders Tourette syndrome, also referred to as Tourette disorder, is a common neurodevelopmental disorder affecting up to 1 percent of the population. It is c ... Read the Article 1.75 20 Activity MD/PA
Trigonocephaly Trigonocephaly is the premature closure of the metopic suture forming a triangular forehead, with an obvious or subtle osseous ridge. This activity re ... Read the Article 1 5 Activity DO
Trigonocephaly Trigonocephaly is the premature closure of the metopic suture forming a triangular forehead, with an obvious or subtle osseous ridge. This activity re ... Read the Article 1 5 Activity MD/PA
Trinucleotide Repeat Disorders Trinucleotide repeat disorders are neuropsychiatric disorders caused due to abnormal trinucleotide repeat expansions. Accurate diagnosis, with knowled ... Read the Article 1 5 Activity DO
Trinucleotide Repeat Disorders Trinucleotide repeat disorders are neuropsychiatric disorders caused due to abnormal trinucleotide repeat expansions. Accurate diagnosis, with knowled ... Read the Article 1 5 Activity MD/PA
Tuberous Sclerosis Tuberous sclerosis complex (TSC) is a genetic disorder that affects multiple systems. It is inherited in an autosomal dominant fashion and is characte ... Read the Article 2 31 Activity DO
Tuberous Sclerosis Tuberous sclerosis complex (TSC) is a genetic disorder that affects multiple systems. It is inherited in an autosomal dominant fashion and is characte ... Read the Article 2 31 Activity MD/PA
Vitamin B5 (Pantothenic Acid) Vitamin B5 is a medication used in the management and treatment of nutrient deficiencies. It is in the dietary supplement class of medications. This a ... Read the Article 1 4 Activity DO
Vitamin B5 (Pantothenic Acid) Vitamin B5 is a medication used in the management and treatment of nutrient deficiencies. It is in the dietary supplement class of medications. This a ... Read the Article 1 4 Activity MD/PA
Waardenburg Syndrome Waardenburg syndrome is a group of genetic conditions inherited in an autosomal dominant fashion. During embryogenesis, there is an abnormal distribut ... Read the Article 1 6 Activity DO
Waardenburg Syndrome Waardenburg syndrome is a group of genetic conditions inherited in an autosomal dominant fashion. During embryogenesis, there is an abnormal distribut ... Read the Article 1 6 Activity MD/PA
Werdnig Hoffmann Disease Werdnig-Hoffmann disease is a type of spinal muscular atrophy (SMA). It is the most common type of SMA and accounts for about 80% of individuals with ... Read the Article 1 5 Activity DO
Werdnig Hoffmann Disease Werdnig-Hoffmann disease is a type of spinal muscular atrophy (SMA). It is the most common type of SMA and accounts for about 80% of individuals with ... Read the Article 1 5 Activity MD/PA
Wyburn-Mason Syndrome Wyburn-Mason syndrome is a rare nonhereditary congenital phakomatoses which presents with multiple arteriovenous malformations that tend to be large a ... Read the Article 1 7 Activity DO
Wyburn-Mason Syndrome Wyburn-Mason syndrome is a rare nonhereditary congenital phakomatoses which presents with multiple arteriovenous malformations that tend to be large a ... Read the Article 1 7 Activity MD/PA

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