This activity has been designed to meet the educational needs of physicians.

At the conclusion of this activity, the learner will be better able to:

• Identify the mechanism of action of various opioid antagonist medications.
• Summarize the different indications for the various opioid antagonist agents.
• Review the adverse event profile of opioid antagonists.
• Outline the importance of collaboration and communication among interprofessional team members to improve outcomes and treatment efficacy for patients who might benefit from therapy with opioid antagonists, especially in light of the ongoing opioid crisis.

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COMMERCIAL SUPPORT: This activity has received NO commercial support.

• Authors: Jonathan Theriot, Sarah Sabir
• Editors: Mohammadreza Azadfard
• Editors-In-Chief: Gregory PlaugherMark V. Pellegrini
  Chief Medical Reviewer: Mark V. Pellegrini
• Nurse Planner/Reviewer: Sandra Coleman
• Pharmacy Planner/Reviewer: Mark V. Pellegrini
• Physician Planner/Reviewer: Scott C. Dulebohn

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Quillen College of Medicine, East Tennessee State University, and StatPearls, LLC. The Quillen College of Medicine, East Tennessee State University is accredited by the ACCME to provide continuing medical education for physicians.

Quillen College of Medicine, East Tennessee State University designates this activity for a maximum of 1.00 AMA PRA Category 1 Credits^TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Instructions for Credit

1. Register for the activity and create a StatPearls login.     
2. Review the target audience, learning objectives, and disclosure information.
3. Study the educational content in the activity.
4. Choose the best answer to each activity test question. To receive credit, you must pass the test questions with a minimum score of 100%.
5. Complete the post-activity assessment.
6. Obtain a certificate.

For information on the applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

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• If you have a question about the ETSU CME providership, please contact wolfes1@etsu.edu.

Disclaimer

Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls specifically disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

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• StatPearlsand and Quillen College of Medicine, East Tennessee State University reserve the right to cancel any course due to unforeseen circumstances. StatPearls andQuillen College of Medicine, East Tennessee State University will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Medium or Media Used:

• Computer Requirements: Internet Access
• E-mail Address

Equal Opportunity

• StatPearls andQuillen College of Medicine, East Tennessee State University are Equal Opportunity/Affirmative Action/Equal Access Institutions. 

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