Alpha-1 Antitrypsin Deficiency

Overview

4.4 out of 5 (8 Reviews)

Credits

1.00

Post Assessment Questions

8

Expiration Date

28 Feb 2026

Last Reviewed

1 Mar 2023

Estimated Time To Finish

60 Minutes


 
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Activity Description

Alpha-1 antitrypsin (AAT) deficiency is a clinically under-recognized genetic disorder that causes the defective production of alpha-1 antitrypsin protein. AAT protein protects the body from the neutrophil elastase enzyme, which is released from white blood cells to fight infection. This activity discusses the evaluation and management of AAT and highlights the role of the interprofessional team in managing and treating the disease to improve patient care.

Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the etiology and epidemiology of alpha-1 antitrypsin deficiency.
  • Explain the common physical exam findings associated with alpha-1 antitrypsin deficiency.
  • Outline the evaluation and management options available for alpha-1 antitrypsin deficiency.
  • Explain the importance of collaboration and communication among the interprofessional team to ensure prompt diagnosis of alpha-1 antitrypsin deficiency to optimize patient management.

Disclosures

StatPearls requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. None of the planners of this educational activity have any relevant financial relationships to disclose.

COMMERCIAL SUPPORT: This activity has received NO commercial support.

Continuing Education Accreditation Information


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Quillen College of Medicine, East Tennessee State University, and StatPearls, LLC. The Quillen College of Medicine, East Tennessee State University is accredited by the ACCME to provide continuing medical education for physicians.

Quillen College of Medicine, East Tennessee State University designates this activity for a maximum of 1.00 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This activity is reported to the following Maintenance of Certification (MOC) boards:
American Board of Internal Medicine
  • Adolescent Medicine
  • Internal Medicine
  • Pulmonary Disease
  • Gastroenterology
American Board of Pathology
  • Clinical Pathology
  • Cytopathology
  • GI (incl. Liver, Pancreas, Bilary)
  • Molecular Genetic Pathology
  • Pulmonary, Mediastinum
American Board of Pediatrics
  • Adolescent Medicine
  • General Pediatrics
  • Pediatric Gastroenterology
  • Pediatric Pulmonology

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content in the activity.
  4. Choose the best answer to each activity test question. To receive credit, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment.
  6. Obtain a certificate.

For information on the applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

Disclaimer

Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls specifically disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Cancellation Policy: Cancellations must be received in writing and a money-back guarantee is provided if not completely satisfied.

  • StatPearlsand and Quillen College of Medicine, East Tennessee State University reserve the right to cancel any course due to unforeseen circumstances. StatPearls andQuillen College of Medicine, East Tennessee State University will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Medium or Media Used:

  • Computer Requirements: Internet Access
  • E-mail Address

Equal Opportunity

  • StatPearls andQuillen College of Medicine, East Tennessee State University are Equal Opportunity/Affirmative Action/Equal Access Institutions. 

 

Media Usage Rights

The contributors and editors of StatPearls have attested that all associated media (images and video) have been legally cleared for use with this activity.  All copyrights are reserved.

  • Name: '1471-2334-4-38-4.jpg' Attribution: Contributed by Anhenn O et al. (published in BMC Infect Dis, v.4; 2004)
  • Name: 'alphaCampbell.png' Attribution: Contributed by chestatlas.com (H. Shulman MD)

Reviews

Henrik H. on 3/31/2021

Yewande A. on 10/31/2021

Goran Gailani O. on 2/4/2022

Louie L. on 5/8/2022

Dr.NIRMALA M. on 11/15/2022

Nice presentation but again, adult oriented and this topic was on the pediatric list.

donald b. on 11/15/2022

Constance J. on 12/8/2022

Ravi J. on 12/30/2022

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