4.5 out of 5 (34 Reviews)



Post Assessment Questions


Expiration Date

28 Feb 2026

Last Reviewed

1 Mar 2023

Estimated Time To Finish

90 Minutes

Need Help?  If you have a system or content concerns, please contact support@statpearls.com

Activity Description

Abetalipoproteinemia is a rare autosomal recessive disorder marked by low or absent levels of plasma cholesterol, low-density lipoproteins, and very-low-density lipoproteins. It should not be confused with a deficiency in beta-lipoproteins. Hallmark symptoms include fat malabsorption, spinocerebellar degeneration, acanthocytosis, and retinitis pigmentosa. This activity reviews the etiology, epidemiology, pathophysiology, evaluation, and treatment considerations of this disease and highlights the role of the collaboration between interprofessional team members.

Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Explain how abetalipoproteinemia manifests in each of the three main organ systems that it affects.
  • Describe anticipated laboratory findings of a patient with abetalipoproteinemia.
  • Outline the treatment of abetalipoproteinemia.
  • Review the importance of collaboration between interprofessional team members for improved recognition and treatment of abetalipoproteinemia.


StatPearls requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. None of the planners of this educational activity have any relevant financial relationships to disclose.

COMMERCIAL SUPPORT: This activity has received NO commercial support.

Continuing Education Accreditation Information

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Quillen College of Medicine, East Tennessee State University, and StatPearls, LLC. The Quillen College of Medicine, East Tennessee State University is accredited by the ACCME to provide continuing medical education for physicians.

Quillen College of Medicine, East Tennessee State University designates this activity for a maximum of 1.50 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This activity is reported to the following Maintenance of Certification (MOC) boards:
American Board of Internal Medicine
  • Adolescent Medicine
  • Endocrinology, Diabetes, and Metabolism
  • Hospital Medicine
  • Internal Medicine
  • Gastroenterology
American Board of Pathology
  • Chemical Pathology
  • GI (incl. Liver, Pancreas, Bilary)
  • Hemostasis & Thrombosis/Coagulation
American Board of Pediatrics
  • Adolescent Medicine
  • General Pediatrics
  • Pediatric Gastroenterology

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content in the activity.
  4. Choose the best answer to each activity test question. To receive credit, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment.
  6. Obtain a certificate.

For information on the applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.


Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls specifically disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Cancellation Policy: Cancellations must be received in writing and a money-back guarantee is provided if not completely satisfied.

  • StatPearlsand and Quillen College of Medicine, East Tennessee State University reserve the right to cancel any course due to unforeseen circumstances. StatPearls andQuillen College of Medicine, East Tennessee State University will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Medium or Media Used:

  • Computer Requirements: Internet Access
  • E-mail Address

Equal Opportunity

  • StatPearls andQuillen College of Medicine, East Tennessee State University are Equal Opportunity/Affirmative Action/Equal Access Institutions. 


Media Usage Rights

The contributors and editors of StatPearls have attested that all associated media (images and video) have been legally cleared for use with this activity.  All copyrights are reserved.

  • Name: 'IMG_20180123_131423.jpg' Attribution: Contributed by Ed Uthman


Venkatraman R. on 10/7/2020

Henrik H. on 3/12/2021

Question more on differentials would help in more concentration on topic read

Dr Haresh D. on 10/12/2021

Gibi G. on 10/13/2021

Raghupathi R. on 12/4/2021

Dr.Mallikarjun K. on 12/15/2021

Tiffany M. on 12/16/2021

Jennifer K. on 2/18/2022

Manish Kumar S. on 3/17/2022

Surabhi C. on 3/22/2022

Rohit A. on 4/8/2022

Murari G. on 4/17/2022

Dr.Mallikarjun K. on 5/1/2022

Ejaz J. on 5/21/2022


saurabh t. on 6/18/2022

dolly k. on 8/24/2022

Bhabesh D. on 5/31/2022

Samir P. on 6/4/2022

K.Navanitha R. on 6/29/2022

Dr Amrita K. on 7/12/2022

Dr Jagveer S. on 8/8/2022

christopher k. on 8/18/2022

Sweta S. on 10/10/2022

Good review of the topic.

John B. on 11/26/2022

SYED M. on 12/3/2022

Arelly J. on 12/9/2022

Dr.NIRMALA M. on 12/21/2022

David J. on 12/21/2022

Larry M. on 12/31/2022

Mitul J. on 2/6/2023

Manish Kumar S. on 2/10/2023

Michael W. on 2/15/2023

Rama Krishna Reddy P. on 2/27/2023

Theodore D. on 3/7/2023

Unlimited Physician CME

Stay up to date on the latest medical knowledge with 6674 CME activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 7931 hours of CME.

Learn About Lifetime CME

Single Activity

Take this single activity

$39 1 activity

6 Month Unlimited Physician CME

Access to all the Unlimited Physician CME activities in all specialties.

$289 per half year per user

1 Year Unlimited Physician CME

Access to all the Unlimited Physician CME activities in all specialties.

$399 per 1 year per user