Amitriptyline

Overview

4.6 out of 5 (98 Reviews)

Credits

1.50

Post Assessment Questions

7

Expiration Date

28 Feb 2026

Last Reviewed

1 Mar 2023

Estimated Time To Finish

90 Minutes


 
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Activity Description

Amitriptyline is FDA approved medication to treat depression in adults. The Non-FDA approved indications are anxiety, post-traumatic stress disorder, insomnia, chronic pain (diabetic neuropathy, fibromyalgia), irritable bowel syndrome, interstitial cystitis (bladder pain syndrome), migraine prophylaxis, postherpetic neuralgia, and sialorrhea. This activity reviews the indications, contraindications, activity, adverse events, and other key elements of amitryptiline in the clinical setting related to the essential points needed by members of an interprofessional team managing the care of patients that can benefit from amitriptyline therapy.

Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the mechanism of action of amitriptyline.
  • Describe FDA-approved and off-label indications of amitriptyline.
  • Review the appropriate adverse drug reactions of amitriptyline.
  • Outline interprofessional team strategies for improving patient outcomes.

Disclosures

StatPearls requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. None of the planners of this educational activity have any relevant financial relationships to disclose.

COMMERCIAL SUPPORT: This activity has received NO commercial support.

Continuing Education Accreditation Information


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Quillen College of Medicine, East Tennessee State University, and StatPearls, LLC. The Quillen College of Medicine, East Tennessee State University is accredited by the ACCME to provide continuing medical education for physicians.

Quillen College of Medicine, East Tennessee State University designates this activity for a maximum of 1.50 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This activity is reported to the following Maintenance of Certification (MOC) boards:
American Board of Anesthesiology
  • Ambulatory/Outpatient
  • General Operative Anesthesia
  • Sleep Medicine
American Board of Internal Medicine
  • Cardiovascular Disease
  • Endocrinology, Diabetes, and Metabolism
  • Internal Medicine
  • Gastroenterology
American Board of Otolaryngology
  • Sleep Medicine
American Board of Pathology
  • Cardiovascular
  • Endocrine
  • GI (incl. Liver, Pancreas, Bilary)
  • Hematology (Blood, BM)
  • Male Genital
  • Neuropathology (incl. Neuromuscular)
  • Urinary Tract
American Board of Pediatrics
  • Pediatric Cardiology
  • Pediatric Endocrinology
  • Pediatric Nephrology
  • Pediatric Neurology
  • Pediatric Pulmonology
  • Sleep Medicine

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content in the activity.
  4. Choose the best answer to each activity test question. To receive credit, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment.
  6. Obtain a certificate.

For information on the applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

Disclaimer

Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls specifically disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Cancellation Policy: Cancellations must be received in writing and a money-back guarantee is provided if not completely satisfied.

  • StatPearlsand and Quillen College of Medicine, East Tennessee State University reserve the right to cancel any course due to unforeseen circumstances. StatPearls andQuillen College of Medicine, East Tennessee State University will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Medium or Media Used:

  • Computer Requirements: Internet Access
  • E-mail Address

Equal Opportunity

  • StatPearls andQuillen College of Medicine, East Tennessee State University are Equal Opportunity/Affirmative Action/Equal Access Institutions. 

 

Media Usage Rights

The contributors and editors of StatPearls have attested that all associated media (images and video) have been legally cleared for use with this activity.  All copyrights are reserved.

    Reviews

    Sharon M. on 7/2/2021

    Alana H. on 8/23/2021

    Erica O. on 9/11/2021

    David G. on 10/4/2021

    Patrick G. on 10/24/2021

    Kimberly A. on 10/29/2021

    April W. on 11/6/2021

    Patricia s. on 12/2/2021

    Thank you

    Douglas T. on 12/5/2021

    NONE AT THIS TIME

    Okechukwu O. on 12/11/2021

    Jeffrey H. on 12/18/2021

    Ketan H. on 11/24/2022

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    Ira on 3/20/2022

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    Stephanie B. on 4/14/2022

    Christopher N. on 5/10/2022

    Michele D. on 5/1/2022

    Samantha B. on 5/6/2022

    There is a vast difference in the questions presented.Some of them give a clear and concise presentation. Meds and conditions are listed and we can make a sound decision. Other questions yield very little information and require us to do a lot of assuming when there in fact, could be multiple different causes for a patient's presentation.

    Paul H. on 5/8/2022

    Jacinta U. on 5/10/2022

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    Dawn E. on 6/16/2022

    Mark W. on 6/16/2022

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    Pamela D. on 6/22/2022

    Appreciate the education!

    Eddie T. on 7/2/2022

    Stephanie C. on 7/3/2022

    Ashley M. on 7/15/2022

    Charles T. on 7/28/2022

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    patricia d. on 10/4/2022

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    Stephanie C. on 1/29/2023

    Lea O. on 1/31/2023

    Ravi J. on 2/10/2023

    jubril o. on 2/11/2023

    thank you

    Melissa S. on 2/14/2023

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    Faiza H. on 5/1/2023

    Allyson K. on 5/3/2023

    Amanda L. on 5/7/2023

    Amy L. on 5/10/2023

    was extremely basic would be wise to add at least cyp2D6 considerations when considering metabolism

    michael s. on 5/18/2023

    Stacie C. on 6/2/2023

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