Antiarrhythmic Medications


4.6 out of 5 (46 Reviews)



Post Assessment Questions


Expiration Date

28 Feb 2026

Last Reviewed

1 Mar 2023

Estimated Time To Finish

90 Minutes

Need Help?  If you have a system or content concerns, please contact

Activity Description

The antiarrhythmic medications have typically been categorized according to the Vaughan-Williams (VW) classification system. The system classifies the medications according to the primary mechanism of action (although several agents retain properties from multiple classes). The VW classification is traditionally broken down into four main categories, with some references adding a fifth. Revised Vaughan-Williams (VW) classification provides insight into the newly developed antiarrhythmic drugs. This activity covers the antiarrhythmic medications and reviews the indications, contraindications, activity, adverse drug reactions, toxicity, management, monitoring parameters, and significant interactions as needed by the interprofessional health team to manage conditions for which these agents are indicated.

Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the main classes of antiarrhythmic medications, and give an example from each.
  • Outline the indications for each class of antiarrhythmic drugs.
  • Summarize the general mechanism of action of antiarrhythmic medications.
  • Describe interprofessional team strategies for improving care coordination and communication to advance appropriate clinical outcomes with antiarrhythmic therapy to treat cardiac arrhythmias and drive the optimal outcomes.


StatPearls requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. None of the planners of this educational activity have any relevant financial relationships to disclose.

COMMERCIAL SUPPORT: This activity has received NO commercial support.

Continuing Education Accreditation Information

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Quillen College of Medicine, East Tennessee State University, and StatPearls, LLC. The Quillen College of Medicine, East Tennessee State University is accredited by the ACCME to provide continuing medical education for physicians.

Quillen College of Medicine, East Tennessee State University designates this activity for a maximum of 1.50 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This activity is reported to the following Maintenance of Certification (MOC) boards:
American Board of Anesthesiology
  • Cardiac Anesthesia
  • Critical Care Medicine
  • Pediatric Anesthesia
American Board of Internal Medicine
  • Adolescent Medicine
  • Advanced Heart Failure and Transplant Cardiology
  • Cardiovascular Disease
  • Clinical Cardiac Electrophysiology
  • Critical Care Medicine
  • Hospital Medicine
  • Internal Medicine
American Board of Pathology
  • Cardiovascular
  • Chemical Pathology
  • Forensic Pathology
American Board of Pediatrics
  • Adolescent Medicine
  • General Pediatrics
  • Hospital Medicine
  • Pediatric Cardiology
  • Pediatric Critical Care Medicine
  • Pediatric Emergency Medicine

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content in the activity.
  4. Choose the best answer to each activity test question. To receive credit, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment.
  6. Obtain a certificate.

For information on the applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.


Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on StatPearls specifically disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Cancellation Policy: Cancellations must be received in writing and a money-back guarantee is provided if not completely satisfied.

  • StatPearlsand and Quillen College of Medicine, East Tennessee State University reserve the right to cancel any course due to unforeseen circumstances. StatPearls andQuillen College of Medicine, East Tennessee State University will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Medium or Media Used:

  • Computer Requirements: Internet Access
  • E-mail Address

Equal Opportunity

  • StatPearls andQuillen College of Medicine, East Tennessee State University are Equal Opportunity/Affirmative Action/Equal Access Institutions. 


Media Usage Rights

The contributors and editors of StatPearls have attested that all associated media (images and video) have been legally cleared for use with this activity.  All copyrights are reserved.

  • Name: 'Illustration of Antiarrhythmics.jpg' Attribution: Contributed by Amandeep Goyal, MD


Deborah Z. on 3/9/2021

John I. on 4/28/2021

cynthia s. on 6/6/2021

Mary G. on 8/4/2021

emma a. on 8/26/2021

Eddie S. on 11/28/2021

Terri C. on 12/22/2021

amanda b. on 12/24/2021

Heather H. on 12/27/2021

Jorge M. on 1/2/2022

Debra F. on 1/3/2022

Catilyn D. on 1/5/2022

Omar S. on 1/10/2022

Kevin C. on 1/24/2022

Anastasiya P. on 1/31/2022

Jennifer J. on 2/22/2022

Jacinta U. on 5/10/2022

Brandy M. on 5/12/2022

Louie L. on 5/18/2022

Lauren S. on 5/19/2022

Deanna K. on 5/25/2022

Carrie H. on 5/30/2022

Stephen A. on 6/1/2022

Laura P. on 6/2/2022

on 6/28/2022

Thomas W. on 7/16/2022

Elizabeth D. on 8/11/2022

John M. on 9/12/2022

siminibe m. on 9/13/2022

gabrielle w. on 10/11/2022

Maylin G. on 10/10/2022

Leon C. on 10/10/2022

Jennifer B. on 10/27/2022

Charles W. on 11/12/2022

Brian G. on 11/27/2022

Adi F. on 12/3/2022

Jacqueline W. on 12/5/2022

Bergen S. on 12/30/2022

Anabela S. on 12/31/2022

Susan H. on 1/10/2023

James R. on 2/12/2023

Skyler S. on 1/19/2023

Scott B. on 2/16/2023

Sarah L. on 2/23/2023

Dakota P. on 3/16/2023

Rose F. on 3/1/2023

Unlimited Physician CME

Stay up to date on the latest medical knowledge with 6674 CME activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 7931 hours of CME.

Learn About Lifetime CME

Single Activity

Take this single activity

$39 1 activity

6 Month Unlimited Physician CME

Access to all the Unlimited Physician CME activities in all specialties.

$289 per half year per user

1 Year Unlimited Physician CME

Access to all the Unlimited Physician CME activities in all specialties.

$399 per 1 year per user