4.7 out of 5 (60 Reviews)



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Expiration Date

28 Feb 2026

Last Reviewed

1 Mar 2023

Estimated Time To Finish

120 Minutes

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Activity Description

Osteosarcoma is a malignant osseous neoplasm. It is the most common primary bone cancer of childhood. Less frequently, it occurs in adults where it represents secondary malignant degeneration of primary bone pathology. This activity reviews the clinical presentation, evaluation, and management of osteosarcoma, and highlights the role of an interprofessional healthcare team in treating patients with this condition.

Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Summarize the pathophysiology of primary and secondary forms of osteosarcoma.
  • Identify the typical imaging findings associated with osteosarcoma.
  • Review the treatment considerations for patients with osteosarcoma.
  • Outline the importance of collaboration and coordination among members of the interprofessional team in managing patients with osteosarcoma.


StatPearls requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. None of the planners of this educational activity have any relevant financial relationships to disclose.

COMMERCIAL SUPPORT: This activity has received NO commercial support.

Continuing Education Accreditation Information

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Quillen College of Medicine, East Tennessee State University, and StatPearls, LLC. The Quillen College of Medicine, East Tennessee State University is accredited by the ACCME to provide continuing medical education for physicians.

Quillen College of Medicine, East Tennessee State University designates this activity for a maximum of 2.00 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This activity is reported to the following Maintenance of Certification (MOC) boards:
American Board of Internal Medicine
  • Internal Medicine
  • Medical Oncology
American Board of Pediatrics
  • General Pediatrics
American Board of Surgery
  • Complex General Surgical Oncology
  • General Surgery
American Board of Pathology
  • Soft Tissue & Bone

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content in the activity.
  4. Choose the best answer to each activity test question. To receive credit, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment.
  6. Obtain a certificate.

For information on the applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.


Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls specifically disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Cancellation Policy: Cancellations must be received in writing and a money-back guarantee is provided if not completely satisfied.

  • StatPearlsand and Quillen College of Medicine, East Tennessee State University reserve the right to cancel any course due to unforeseen circumstances. StatPearls andQuillen College of Medicine, East Tennessee State University will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Medium or Media Used:

  • Computer Requirements: Internet Access
  • E-mail Address

Equal Opportunity

  • StatPearls andQuillen College of Medicine, East Tennessee State University are Equal Opportunity/Affirmative Action/Equal Access Institutions. 


Media Usage Rights

The contributors and editors of StatPearls have attested that all associated media (images and video) have been legally cleared for use with this activity.  All copyrights are reserved.

  • Name: 'osteogenic sarcoma.jpg' Attribution: Contributed by Scott Dulebohn, MD
  • Name: 'osteosarcoma.jpg' Attribution: Contributed by Scott Dulebohn, MD
  • Name: 'telangiectactic OS.png' Attribution: Image courtesy S Bhimji MD


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Treasa G. on 8/1/2022

Yuliya N. on 7/30/2022

Erica M. on 7/31/2022

Thykle C. on 7/31/2022

I appreciate the clinical cases to deepen the subject of the article.

Dung N. on 8/3/2022

Ernest S. on 8/2/2022

April M. on 8/2/2022

Sara C. on 8/3/2022

Melissa S. on 8/4/2022


victor gbenga s. on 8/4/2022

Asta B. on 8/6/2022

Said A. on 8/6/2022

Jeromy P. on 8/11/2022

Jiewen Z. on 8/8/2022

Jessica S. on 8/8/2022

Ishanjit s. on 8/9/2022

Leon K. on 8/9/2022

L. Michelle S. on 8/9/2022

thank you good course

Cheryl S. on 8/10/2022

Becky O. on 8/11/2022

Barbara W. on 8/11/2022

Timothy C. on 8/13/2022

Christina L. on 8/13/2022

Sandra C. on 8/14/2022

Amber D. on 8/14/2022

Allison B. on 8/14/2022

Boring presentation that was too technical with very difficult follow up exam that poorly correlated to the material presented.

Mary P. on 8/15/2022

Gerlande P. on 8/15/2022

Edda R. on 8/16/2022

Jean L. on 8/16/2022

Dana T. on 8/18/2022

Very useful education!

Jill M. on 8/18/2022

Talia F. on 8/18/2022

Eric C. on 8/18/2022

Adam G. on 8/22/2022

Brittney S. on 8/20/2022

jacqueline b. on 8/21/2022

Amanda D. on 8/22/2022

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Lhoryfel V. on 8/23/2022

Kelly B. on 8/23/2022

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kelly g. on 8/24/2022

Andrea O. on 8/25/2022

Thomas B. on 9/10/2022

Kaitlyn G. on 12/9/2022

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