Rheumatoid Arthritis


4.4 out of 5 (21 Reviews)



Post Assessment Questions


Expiration Date

28 Feb 2026

Last Reviewed

1 Mar 2023

Estimated Time To Finish

120 Minutes

Need Help?  If you have a system or content concerns, please contact support@statpearls.com

Activity Description

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by inflammatory arthritis and extra-articular involvement. It is a chronic inflammatory disorder caused in many cases by the interaction between genes and environmental factors, including tobacco, that primarily involves synovial joints. It typically starts in small peripheral joints, is usually symmetric, and progresses to involve proximal joints if left untreated. Joint inflammation over time leads to the destruction of the joint with loss of cartilage and bone erosions. RA with a symptom duration of fewer than six months is defined as early RA, and when the symptoms have been present for more than six months, it is defined as established RA. RA, if untreated, is a progressive disease with morbidity and increased mortality. This activity describes the evaluation and management of rheumatoid arthritis and reviews the role of the interprofessional team in improving care for patients with this condition.

Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the comorbid conditions associated with rheumatoid arthritis.
  • Summarize the pathophysiology of rheumatoid arthritis.
  • Outline the use of rheumatoid factor and anti-citrullinated protein antibodies in evaluating rheumatoid arthritis.
  • Review the importance of improving care coordination among the interprofessional team to improve outcomes for those affected with rheumatoid arthritis.


StatPearls requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. None of the planners of this educational activity have any relevant financial relationships to disclose.

COMMERCIAL SUPPORT: This activity has received NO commercial support.

Continuing Education Accreditation Information

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Quillen College of Medicine, East Tennessee State University, and StatPearls, LLC. The Quillen College of Medicine, East Tennessee State University is accredited by the ACCME to provide continuing medical education for physicians.

Quillen College of Medicine, East Tennessee State University designates this activity for a maximum of 2.00 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This activity is reported to the following Maintenance of Certification (MOC) boards:
American Board of Internal Medicine
  • Internal Medicine
  • Rheumatology
American Board of Pediatrics
  • General Pediatrics
  • Pediatric Rheumatology

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content in the activity.
  4. Choose the best answer to each activity test question. To receive credit, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment.
  6. Obtain a certificate.

For information on the applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.


Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls specifically disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Cancellation Policy: Cancellations must be received in writing and a money-back guarantee is provided if not completely satisfied.

  • StatPearlsand and Quillen College of Medicine, East Tennessee State University reserve the right to cancel any course due to unforeseen circumstances. StatPearls andQuillen College of Medicine, East Tennessee State University will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Medium or Media Used:

  • Computer Requirements: Internet Access
  • E-mail Address

Equal Opportunity

  • StatPearls andQuillen College of Medicine, East Tennessee State University are Equal Opportunity/Affirmative Action/Equal Access Institutions. 


Media Usage Rights

The contributors and editors of StatPearls have attested that all associated media (images and video) have been legally cleared for use with this activity.  All copyrights are reserved.

  • Name: 'RA.jpg' Attribution: Contributed by StatPearls
  • Name: 'TENOSYNOVITIS 34460057_US EXTREMITY COMPLETE 76881_24_0.jpg' Attribution: Contributed by Mike Tall, MD
  • Name: 'granuloma ann03.jpg' Attribution: Contributed by Fabiola Farci, MD


Henrik H. on 2/12/2021

Ralph C. on 3/28/2021

Lisa R. on 9/28/2021

Stephanie K. on 12/1/2021

Santiago C. on 12/9/2021

Kathryn C. on 1/9/2022

Melanie G. on 1/15/2022

jasmine m. on 3/20/2022

Louie L. on 4/12/2022

Elizabeth W. on 5/19/2022

Gayle W. on 6/7/2022

Fernando E. on 9/27/2022

Clifford A. on 11/17/2022

Maylin G. on 11/15/2022

Ingerlisa M. on 12/25/2022

Claudia M. on 12/28/2022

Holly C. on 1/31/2023

Matthew N. on 4/10/2023

Alina B. on 4/12/2023

Catherine S. on 5/16/2023


Joseph D. on 5/22/2023

Unlimited Physician CME

Stay up to date on the latest medical knowledge with 6673 CME activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 7930 hours of CME.

Learn About Lifetime CME

Single Activity

Take this single activity

$58.5 1 activity

6 Month Unlimited Physician CME

Access to all the Unlimited Physician CME activities in all specialties.

$289 per half year per user

1 Year Unlimited Physician CME

Access to all the Unlimited Physician CME activities in all specialties.

$399 per 1 year per user