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Antiemetic Serotonin-5-HT3 Receptor Blockers |
Credits: 1.00 Post-Assessment Questions: 5
Release Date: 5 Oct 2020
Expiration Date: 23 Dec 2021
Last Reviewed: 23 Dec 2020
Estimated Time To Finish: 60 Minutes
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Selective serotonin receptor (5-HT3) antagonists block serotonin both peripherally, on gastrointestinal (GI) vagal nerve terminals, and centrally in the chemoreceptor trigger zone. This blockade results in powerful antiemetic effects. 5-HT3 receptor antagonists are FDA-approved for the prevention of nausea and vomiting in children and adults related to chemotherapy use, radiation therapy, and the effects of postoperative anesthesia. This activity reviews the indications, contraindications, activity, adverse events, and other key elements of antiemetic 5-HT3 receptor antagonists in the clinical setting as relates to the essential points needed by members of an interprofessional team managing the care of patients who can benefit therapeutically from these agents.
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Authors: Jonathan Theriot, Harrison Wermuth
Editors: John Ashurst
Editors-In-Chief: Gregory PlaugherMark Pellegrini
Chief Medical Reviewer: Charles Preuss
Nurse Planner/Reviewer/Editor: Lisa Haddad
Nurse Planner/Reviewer/Editor: Bernadette Makar
Nurse Planner/Reviewer/Editor: Dorothy Caputo
Pharmacy Planner/Reviewer/Editor: Mark Pellegrini
Physician Planner/Reviewer/Editor: Scott Dulebohn
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Quillen College of Medicine, East Tennessee State University designates this activity for a maximum of 1.00 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.
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