Lambert Eaton Myasthenic Syndrome

Overview

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Credits

1.00

Post Assesment Questions

5

Release Date

5 Oct 2020

Expiration Date

15 Jul 2021

Last Reviewed

15 Jul 2020

Estimated Time To Finish

60 Minutes

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Activity Description

Lambert-Eaton myasthenic syndrome (LEMS) is a neuromuscular junction disorder which may present as a paraneoplastic phenomenon or a primary autoimmune disorder. More than half of the cases are associated with small cell lung cancer (SCLC). The primary clinical manifestation is muscle weakness. The pathology is due to the generation of antibodies against voltage-gated calcium channels (VGCC) on presynaptic nerve terminals leading to a decrease in the neurotransmitter acetylcholine (ACh). This topic will review the pathogenesis, diagnostic testing, and treatment of Lambert-Eaton myasthenic syndrome. This activity reviews the pathophysiology of Lambert-Eaton syndrome and highlights the role of the interprofessional team in its management.

Target Audience

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the cause of Lambert-Eaton syndrome.
  • Describe the pathophysiology of Lambert-Eaton myasthenic syndrome.
  • Summarize the treatment of Lambert-Eaton myasthenic syndrome.
  • Explain modalities to improve care coordination among interprofessional team members in order to improve outcomes for patients affected by Lambert-Eaton syndrome.

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