Methotrexate

Overview

4.6 out of 5 (128 Reviews)

Credits

2.00

Post Assessment Questions

10

Start Date

19 Jul 2022

Last Review Date

16 Aug 2023

Expiration Date

31 Dec 2023

Estimated Time To Finish

120 Minutes


 
Need Help?  If you have a system or content concerns, please contact support@statpearls.com

Activity Description

Methotrexate (MTX) is an anti-metabolite most commonly used in chemotherapy and immunosuppressant in auto-immune diseases. This activity describes the indications, action, and contraindications for Methotrexate as a valuable agent in treating a wide variety of neoplastic diseases. This activity will highlight the mechanism of action, adverse event profile, and other key factors (uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent for members of the interprofessional healthcare team in managing patients with cancer and auto-immune conditions.


Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Describe the mechanism of action of methotrexate in chemotherapy as well as in autoimmune diseases.

  • Identify the common and rare but serious adverse events associated with methotrexate use.

  • Outline the typical presentations of methotrexate toxicity and how to manage it.

  • Review the importance of patient education before starting treatment with methotrexate in any disease to sustain continuity of treatment, prevent morbidity to a greater extent, and increase life expectancy in cancer patients.

Disclosures

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Continuing Education Accreditation Information

 

 

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 2.00 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

 

 
 

Reviews

Terri C. on 12/22/2021

Amelia G. on 1/17/2022

Jennifer J. on 2/19/2022

Mary Y. on 5/16/2022

Mike B. on 5/16/2022

Ana W. on 6/6/2022

on 6/23/2022

Aimee S. on 6/26/2022

Jennifer L. on 7/6/2022

Zoe M. on 7/26/2022

Kara C. on 8/9/2022

Michael A. on 8/23/2022

PATIENCE A. on 9/13/2022

Mary M. on 9/14/2022

Michael D. on 9/17/2022

Nicole G. on 9/24/2022

jesse D. on 10/23/2022

Theodore B. on 11/3/2022

Good activity.

Kelly A. on 11/28/2022

saundria p. on 11/28/2022

Jacqueline W. on 12/1/2022

Nextgen l. on 12/4/2022

Nancy M. on 12/9/2022

Anne R. on 12/27/2022

Martha A. on 12/27/2022

Stephanie S. on 1/10/2023

Skyler S. on 1/26/2023

jubril o. on 2/8/2023

Trisha K. on 2/10/2023

Ashleigh R. on 2/11/2023

on 2/13/2023

Heather H. on 2/26/2023

Megan M. on 3/1/2023

Elizabeth H. on 3/17/2023

Kelly C. on 3/27/2023

Quarshiwaa A. on 4/13/2023

Jana M. on 4/16/2023

Valerie B. on 4/21/2023

Deborah V. on 5/20/2023

Amanda L. on 5/7/2023

Ron H. on 5/17/2023

Emily B. on 5/24/2023

James N. on 6/1/2023

Elaine N. on 6/2/2023

Bonnie R. on 6/5/2023

Louie L. on 7/15/2023

none

Alvin O. on 6/10/2023

Krista B. on 6/13/2023

Kyle p. on 6/18/2023

Stephanie D. on 6/17/2023

Emily L. on 6/28/2023

Christy S. on 6/29/2023

Kimberly H. on 6/30/2023

Kevin M. on 7/2/2023

Mary Y. on 7/6/2023

Keisha D. on 7/8/2023

Michele N. on 7/8/2023

Megan B. on 7/11/2023

Rachel E. on 7/12/2023

Morgan C. on 7/19/2023

Peter W. on 7/21/2023

Hannah B. on 7/23/2023

Amy G. on 7/23/2023

Astrid S. on 7/24/2023

Kara W. on 8/15/2023

Sydney B. on 8/20/2023

Laura K. on 8/22/2023

Aaren M. on 8/25/2023

Lauren E. on 9/7/2023

Astasia G. on 9/20/2023

Jessica H. on 9/12/2023

Cathy R. on 9/20/2023

Jarrod G. on 9/28/2023

Jeff P. on 9/30/2023

Matthew C. on 10/3/2023

Mackenzie H. on 10/19/2023

Sandra R. on 10/19/2023

Daniel T. on 10/24/2023

Sarah B. on 10/25/2023

Darren S. on 10/26/2023

Faith M. on 10/27/2023

Puja P. on 10/27/2023

Ashley C. on 11/6/2023

Carol I. on 11/3/2023

NO A. on 11/5/2023

Kristie C. on 11/6/2023

Everett M. on 11/7/2023

Chih-Tao H. on 11/22/2023

Brandon B. on 11/25/2023

Amy V. on 12/2/2023

Sara D. on 12/4/2023

Robert d. on 12/10/2023

Joanne Z. on 12/17/2023

Medha D. on 12/21/2023

Theodore B. on 12/22/2023

valerie b. on 12/24/2023

Aeyrie R. on 12/25/2023

Amber E. on 12/27/2023

Erika G. on 12/29/2023

Stephen B. on 12/31/2023

Astrid S. on 1/9/2024

Lauren B. on 1/10/2024

Micaela W. on 1/13/2024

Audrey D. on 1/16/2024

Erika G. on 1/16/2024

paul n. on 1/19/2024

Chelsea V. on 1/26/2024

Morgan M. on 1/27/2024

Marti E. on 1/29/2024

Emma U. on 2/1/2024

Stacy W. on 2/11/2024

Jennifer M. on 2/20/2024

Kelly T. on 2/21/2024

Klaus M. on 3/4/2024

THERESA M. on 3/4/2024

Brittany H. on 3/11/2024

Isaac R. on 3/24/2024

Elizabeth A. on 3/25/2024

Lauren H. on 3/27/2024

KEN P. on 3/31/2024

Mohammad I. on 3/31/2024

Kristine G. on 4/2/2024

Jerry D. on 4/7/2024

Melissa C. on 4/8/2024

Gretchen O. on 4/11/2024

Tracie P. on 4/13/2024

Megan M. on 4/17/2024

Robert S. on 4/17/2024

Unlimited Physician CME

Stay up to date on the latest medical knowledge with 6673 CME activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 7923.5 hours of CME.

Learn About Lifetime CME

Single Activity

Take this single activity

$39 1 activity

6 Month Unlimited Physician CME

Access to all the Unlimited Physician CME activities in all specialties.

$399 per half year per user

1 Year Unlimited Physician CME

Access to all the Unlimited Physician CME activities in all specialties.

$599 per 1 year per user