Warfarin Drug Interactions

Overview

4.6 out of 5 (51 Reviews)

Credits

1.50

Post Assessment Questions

10

Start Date

1 Jan 2021

Last Review Date

1 May 2023

Expiration Date

31 Dec 2023

Estimated Time To Finish

90 Minutes


 
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Activity Description

Warfarin has FDA approval for the prophylaxis and treatment of venous thrombosis and its complications, such as a pulmonary embolus. It is also indicated to prevent thromboembolic complications associated with conditions such as atrial fibrillation, cardiac valve replacement, and inherited genetic factors like C and S protein deficiency or Factor V Leiden. Additionally, warfarin is FDA approved as an adjunct to reduce the risk of myocardial infarction (MI) and other thromboembolic events in high-risk patients. However, warfarin falls in the narrow therapeutic index drug category and is subject to numerous interactions. This activity outlines the indications, mechanism of action, interactions, significant adverse effects, contraindications, toxicity, and warfarin monitoring so providers can direct patient therapy where anticoagulation is indicated as part of the interprofessional team.

Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the mechanism of action of warfarin.
  • Review the agents that can either increase or decrease the anticoagulant effect of warfarin.
  • Summarize the target INR levels for warfarin therapy based on conditions that affect INR targets.
  • Describe the importance of collaboration and coordination among the interprofessional team and how it can enhance patient care with warfarin therapy in conjunction with the patient's entire medication regimen to improve patient outcomes for patients with conditions where anticoagulation is indicated.

Disclosures

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Continuing Education Accreditation Information

 

 

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.50 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

 

 
 

Reviews

Valentine C. on 4/14/2021

Edward I. on 7/31/2021

Barbara C. on 8/17/2021

Peggy K. on 9/14/2021

marshall s. on 12/4/2021

Stephen M. on 12/29/2021

Basil R. on 1/5/2022

Mary Y. on 3/16/2022

Lori N. on 4/16/2022

Emmy K. on 5/11/2022

Christine D. on 5/16/2022

Emily V. on 6/30/2022

Noah S. on 7/28/2022

Kathryn C. on 8/22/2022

Alex N. on 8/30/2022

Amanda F. on 9/12/2022

Rayon S. on 11/16/2022

Tara D. on 12/8/2022

Great

Kenneth R. on 12/10/2022

Kecia T. on 12/24/2022

Nicole M. on 12/31/2022

Deborah M. on 1/8/2023

Lisa B. on 1/30/2023

Christine G. on 3/14/2023

Amy A. on 4/7/2023

Nicole S. on 5/3/2023

Expand this course to include more drugs and icrease CEUs to 3.

JAMI W. on 5/27/2023

would be helpful to have a more comprehensive list/table of drug interactions w/warfarin.

Angela D. on 6/6/2023

Leah S. on 6/12/2023

VLADIMIR E. on 6/29/2023

Terry P. on 8/19/2023

Rey V. on 8/17/2023

Van J. on 8/22/2023

Yan L. on 9/28/2023

Matthew V. on 10/11/2023

Kimberly R. on 11/1/2023

Christopher E. on 11/2/2023

SUSAN L. on 11/5/2023

debbie s. on 11/10/2023

Jennifer L. on 11/13/2023

Sarah G. on 11/22/2023

SAMER E. on 11/30/2023

MICHELLE B. on 12/4/2023

Jakob H. on 12/29/2023

Erika B. on 12/29/2023

camille j. on 1/3/2024

Stephen B. on 1/1/2024

Mary M. on 2/17/2024

Louie L. on 2/25/2024

Janet P. on 3/19/2024

Kathleen K. on 3/29/2024

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