Warfarin Toxicity

Overview

4.6 out of 5 (37 Reviews)

Credits

1.50

Post Assessment Questions

11

Start Date

1 Jan 2021

Last Review Date

17 Jul 2023

Expiration Date

31 Dec 2023

Estimated Time To Finish

90 Minutes


 
Need Help?  If you have a system or content concerns, please contact support@statpearls.com

Activity Description

Warfarin is a vitamin K antagonist used as an anticoagulant used for treatment and prevention of a variety of coagulopathic and thromboembolic disorders. While it was initially marketed as a rodenticide, it has been used as a medication for more than a half-century. Superwarfarins are now also used as pesticides and should be recognized as having potential to cause warfarin toxicity. They are one hundred times more potent than warfarin. Toxicity can occur due to intentional overdose, unintentional overdose, and pediatric ingestion. Intentional overdose has been noted to be relatively rare; a 25-year long survey involving 2 tertiary care centers with toxicology services reported a total of 22 intentional overdoses in adults. Unintentional overdose or toxicity can occur through various mechanisms such as during the initial dose titration phase, with changes in diet that affect the medication potency, due to interactions with other medications, or secondary to metastatic liver disease. This activity describes the pathophysiology of warfarin toxicity and highlights the role of the interprofessional team in its management.

Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Describe the presentation of a patient with warfarin toxicity.
  • Summarize the causes of warfarin toxicity.
  • Outline the treatment options for warfarin toxicity.
  • Explain the importance of improving care coordination amongst interprofessional team members to improve outcomes for patients affected by warfarin toxicity.

Disclosures

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Continuing Education Accreditation Information

 

 

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.50 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

 

 
 

Reviews

Kathryn T. on 9/7/2021

Emmy K. on 5/11/2022

Louie L. on 8/16/2022

Matthew S. on 9/7/2022

Sanjeev S. on 11/11/2022

Great

Kenneth R. on 12/10/2022

none

shawna v. on 12/20/2022

Nicole M. on 12/31/2022

Natalie p. on 1/2/2023

Deborah M. on 2/23/2023

Sharon B. on 2/12/2023

Theodore K. on 5/17/2023

Janet P. on 5/26/2023

Corazon B. on 6/26/2023

Dr Sruthi G. on 7/27/2023

Terry P. on 8/12/2023

john a. on 8/27/2023

Sonia A. on 9/22/2023

Ehsan Q. on 9/22/2023

Ryan P. on 10/3/2023

Swaminathan I. on 10/26/2023

prabhakar r. on 11/22/2023

SAMER E. on 11/30/2023

Tyrone G. on 12/8/2023

THERESA H. on 12/17/2023

John M. on 12/22/2023

sandhya s. on 12/22/2023

Erika B. on 12/29/2023

Jason D. on 12/30/2023

Tyrone G. on 1/6/2024

Brian B. on 1/15/2024

Jonathan A. on 1/27/2024

Mary M. on 2/17/2024

Katayun S. on 2/24/2024

Mohammad G. on 4/10/2024

Lawrence S. on 4/21/2024

Tarahn A. on 4/22/2024

Unlimited Physician CME

Stay up to date on the latest medical knowledge with 6673 CME activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 7923.5 hours of CME.

Learn About Lifetime CME

Single Activity

Take this single activity

$58.50 1 activity

6 Month Unlimited Physician CME

Access to all the Unlimited Physician CME activities in all specialties.

$399 per half year per user

1 Year Unlimited Physician CME

Access to all the Unlimited Physician CME activities in all specialties.

$599 per 1 year per user