Septic Shock

Overview

4.7 out of 5 (43 Reviews)

Credits

1.50

Post Assessment Questions

12

Start Date

3 Nov 2022

Last Review Date

12 Jun 2023

Expiration Date

31 Dec 2023

Estimated Time To Finish

90 Minutes


 
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Activity Description

Sepsis syndromes span a clinical continuum with variable prognoses. Septic shock, the most severe complication of sepsis, carries a high mortality. Septic shock occurs in response to an inciting agent, which causes both pro-inflammatory and anti-inflammatory immune system activation. This occurs in concert with the activation of monocytes, macrophages, and neutrophils that interact with the endothelium through pathogen recognition receptors and lead to further involvement of cytokines, proteases, kinins, reactive oxygen species, and nitric oxide. As the primary site of this response, the endothelium not only suffers microvascular injury but also activates the coagulation and complement cascades, which further exacerbate the vascular injury, leading to capillary leakage. This cascade of events is responsible for the clinical signs and symptoms of sepsis and progression from sepsis to septic shock. Striking a balance between pro-inflammatory responses, which help eradicate the invading microorganism, and anti-inflammatory signals, which keep the inflammatory cascade in check, ultimately determines the degree of morbidity and/or mortality of patients with sepsis. Judicious and early antimicrobial administration, sepsis care bundle use, and early goal-directed therapies have significantly and positively impacted sepsis-related mortality. However, early identification remains the best therapeutic tool for sepsis treatment and management. This activity describes the evaluation and management of septic shock and highlights the role of the interprofessional team in enhancing care delivery for affected patients.


Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Review the causes of septic shock.

  • Describe the pathophysiology of septic shock.

  • Outline the treatment options for septic shock.

  • Explain the importance of improving care coordination amongst interprofessional team members to improve outcomes for patients affected by septic shock.

Disclosures

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Continuing Education Accreditation Information

 

 

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.50 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

 

 
 

Reviews

Michael S. on 12/20/2020

Denise B. on 5/14/2021

i dont like you are makeing me do these evaluation to get the certificate

Rafael J. on 6/16/2021

Robert R. on 7/28/2021

Lisa S. on 8/13/2021

Has to include the use of hemodynamic monitoring such as PPV, PiCCO, and PAC, ultrasonography

Thiago C. on 9/10/2021

Linda B. on 9/2/2021

Eileen M. on 9/14/2021

John M. on 10/6/2021

saurabh t. on 9/5/2022

Jafet B. on 11/9/2021

Melissa H. on 1/2/2022

Dr.Mallikarjun K. on 1/20/2022

Thomas B. on 9/10/2022

Meldyne H. on 10/3/2022

Alok P. on 12/11/2022

reno l. on 12/11/2022

Philip S. on 12/18/2022

Dr.NIRMALA M. on 1/2/2023

Mary K. on 1/28/2023

Matthew N. on 1/31/2023

evan s. on 3/4/2023

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Lily L. on 7/4/2023

Catherine R. on 8/22/2023

Gretchen G. on 8/27/2023

Nicole F. on 9/18/2023

Alan Y. on 9/27/2023

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