Leukocytosis

Overview

4.5 out of 5 (11 Reviews)

Credits

1.50

Post Assessment Questions

9

Start Date

1 Jan 2021

Last Review Date

21 Apr 2024

Expiration Date

31 Dec 2023

Estimated Time To Finish

90 Minutes


 
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Activity Description

Leukocytosis, characterized by an elevation in the white blood cell count, is a common clinical finding with various potential causes, encompassing infections, inflammation, malignancies, and hereditary disorders. The threshold for leukocytosis varies with age and pregnancy status, with significant deviations from typical values prompting further evaluation. Identifying changes in the distribution of white blood cells aids in pinpointing the underlying cause, such as eosinophilia indicating allergic reactions or parasitic infections and lymphocytosis suggestive of viral syndromes or autoimmune diseases. While many cases of leukocytosis resolve without intervention, some may necessitate urgent evaluation for leukemia or myeloproliferative disorders.

Evaluating leukocytosis involves assessing clinical features, duration of results, the differential, and remaining complete blood count parameters. In cases of persistent leukocytosis, bone marrow aspiration and biopsy may be necessary to differentiate leukemia from benign conditions. Treatment of leukocytosis is often not required. Cases of leukemia, lymphoma, or hyperleukocytosis syndrome, where interventions like leukapheresis and chemotherapy may be necessary, are exceptions. Management strategies address the underlying etiology, emphasizing a comprehensive approach to patient care guided by diagnostic findings and clinical expertise. 

This activity discusses the etiology and pathophysiology of leukocytosis, offering nuanced perspectives on its assessment. Healthcare professionals will gain invaluable insights into accurately evaluating leukocytosis and employing evidence-based treatment strategies, emphasizing the importance of tailored management plans directed at the underlying cause. This comprehensive course empowers clinicians with essential knowledge and resources to optimize care for patients with this prevalent condition.


Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Differentiate between benign leukocytosis and conditions warranting urgent evaluation, such as hyperleukocytosis syndrome or leukemia.

  • Assess the need for further investigations, such as bone marrow biopsy, in cases of persistent leukocytosis to evaluate for malignancies.

  • Implement evidence-based treatment strategies for leukocytosis.

  • Collaborate with an interprofessional healthcare team to optimize patient care and coordinate transitions between care settings.

Disclosures

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Continuing Education Accreditation Information

 

 

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.50 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

 

 
 

Reviews

Trista P. on 8/15/2021

Diane P. on 11/14/2021

Ronita B. on 7/2/2022

Harriette S. on 8/1/2022

Katrina T. on 8/18/2022

Richard H. on 12/25/2022

Swaminathan I. on 8/25/2023

Richard S. on 12/21/2023

Jeffrey W. on 1/15/2024

Dr Sruthi G. on 2/13/2024

Kelli M. on 4/11/2024

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