Krukenberg Tumor

Overview

4 out of 5 (3 Reviews)

Credits

1.00

Post Assessment Questions

6

Start Date

1 Jan 2021

Last Review Date

20 Apr 2024

Expiration Date

31 Dec 2023

Estimated Time To Finish

60 Minutes


 
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Activity Description

Krukenberg tumor is a metastatic signet-ring cell adenocarcinoma of the ovary characterized by mucin-rich, signet-ring cells, originating from a gastrointestinal primary in 70% of cases, but also involving the colon, breast, appendix, and biliary tract. The incidence of Krukenberg tumors ranges from 1% to 21%, most common in Asian countries due to the increased prevalence of gastric cancer. Krukenberg tumors are often bilateral and can be solid, cystic, or a combination. Immunohistochemistry stains can help distinguish Krukenberg from primary ovarian cancer. Because Krukenburg tumors present with nonspecific symptoms, the diagnosis is frequently delayed. Krukenberg tumors occur in younger women compared with an ovarian primary. The prognosis is poor, but an overall survival benefit has been shown with palliative surgical resection.

This course provides a comprehensive overview of Krukenberg tumors, focusing on epidemiology, clinical presentation, evaluation, and treatment. Participants will gain insights into the diverse origins of these tumors, and emphasis is placed on the challenges in timely diagnosis due to nonspecific symptoms, highlighting the need for vigilant clinical evaluations. Additionally, clinicians will delve into the significance of tumor markers in prognosis and treatment decisions. The course concludes with a nuanced discussion of treatment strategies, encompassing surgery, chemotherapy, targeted immunotherapy, and radiation, acknowledging the absence of standardized guidelines and the importance of an individualized, interdisciplinary approach. The course equips healthcare professionals with the knowledge and tools necessary to navigate the complexities of Krukenberg tumors and optimize patient care outcomes.


Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Apply screening protocols for patients at risk, emphasizing early detection and timely intervention in the presence of nonspecific symptoms associated with Krukenberg tumors

  • Identify key clinical indicators and imaging features to promptly recognize Krukenberg tumors, distinguishing them from primary ovarian malignancies.

  • Implement evidence-based treatment strategies, including surgery and chemotherapy, tailored to the individual patient's tumor biology and functional status.

  • Collaborate with an interdisciplinary team, including oncologists, radiologists, and pathologists, to ensure a holistic and coordinated approach to Krukenberg tumor management.

Disclosures

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Continuing Education Accreditation Information

 

 

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.00 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

 

 
 

Reviews

Michael B. on 11/30/2021

Ron H. on 4/28/2023

Henry X. on 3/18/2024

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