Chloroquine and Hydroxychloroquine Toxicity

Overview

4.6 out of 5 (13 Reviews)

Credits

1.50

Post Assessment Questions

7

Start Date

1 Jan 2021

Last Review Date

11 Jan 2024

Expiration Date

31 Dec 2023

Estimated Time To Finish

90 Minutes


 
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Activity Description

Chloroquine and hydroxychloroquine are 4-aminoquinoline compounds that are commonly used in the prevention and treatment of malaria. Hydroxychloroquine is also frequently used in the treatment of rheumatologic diseases such as systemic lupus erythematosus and gained notoriety during the COVID-19 pandemic when it was used experimentally in the treatment of SARS-CoV-2 infection. As the use of these drugs is common and spans many indications, the interprofessional healthcare team should be aware of potential drug toxicities and how to manage them.  This activity reviews the indications for use, mechanisms of action, pharmacokinetics, potential toxicities, and management of toxicities related to chloroquine and hydroxychloroquine.  Furthermore, this activity will empower members of the interprofessional healthcare team to recognize, treat, and mitigate chloroquine and hydroxychloroquine toxicity in the patients they serve.   


Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the treatment indications for chloroquine and hydroxychloroquine.

  • Determine the mechanisms of action of chloroquine and hydroxychloroquine. 

  • Identify the presence of chloroquine or hydroxychloroquine toxicities in patients. 

  • Collaborate with the interprofessional healthcare team to implement appropriate management strategies in patients with chloroquine or hydroxychloroquine toxicity.

Disclosures

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Continuing Education Accreditation Information

 

 

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.50 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

 

 
 

Reviews

OSCAR P. on 5/22/2021

Janice on 3/4/2022

Stephanie u. on 11/7/2022

James A. on 11/26/2022

Holly J. on 12/11/2022

efstathia c. on 12/28/2022

Christine G. on 3/2/2023

Kinga V. on 4/30/2023

Tracy b. on 8/27/2023

John T. on 9/17/2023

Malia B. on 12/26/2023

Erika G. on 1/16/2024

THERESA M. on 3/4/2024

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