Krukenberg Tumor

Overview

4 out of 5 (3 Reviews)

Credits

1.00

Post Assessment Questions

6

Start Date

1 Sep 2023

Last Review Date

20 Apr 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


 
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Activity Description

Krukenberg tumor is a metastatic signet-ring cell adenocarcinoma of the ovary characterized by mucin-rich, signet-ring cells, originating from a gastrointestinal primary in 70% of cases, but also involving the colon, breast, appendix, and biliary tract. The incidence of Krukenberg tumors ranges from 1% to 21%, most common in Asian countries due to the increased prevalence of gastric cancer. Krukenberg tumors are often bilateral and can be solid, cystic, or a combination. Immunohistochemistry stains can help distinguish Krukenberg from primary ovarian cancer. Because Krukenburg tumors present with nonspecific symptoms, the diagnosis is frequently delayed. Krukenberg tumors occur in younger women compared with an ovarian primary. The prognosis is poor, but an overall survival benefit has been shown with palliative surgical resection.

This course provides a comprehensive overview of Krukenberg tumors, focusing on epidemiology, clinical presentation, evaluation, and treatment. Participants will gain insights into the diverse origins of these tumors, and emphasis is placed on the challenges in timely diagnosis due to nonspecific symptoms, highlighting the need for vigilant clinical evaluations. Additionally, clinicians will delve into the significance of tumor markers in prognosis and treatment decisions. The course concludes with a nuanced discussion of treatment strategies, encompassing surgery, chemotherapy, targeted immunotherapy, and radiation, acknowledging the absence of standardized guidelines and the importance of an individualized, interdisciplinary approach. The course equips healthcare professionals with the knowledge and tools necessary to navigate the complexities of Krukenberg tumors and optimize patient care outcomes.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Apply screening protocols for patients at risk, emphasizing early detection and timely intervention in the presence of nonspecific symptoms associated with Krukenberg tumors

  • Identify key clinical indicators and imaging features to promptly recognize Krukenberg tumors, distinguishing them from primary ovarian malignancies.

  • Implement evidence-based treatment strategies, including surgery and chemotherapy, tailored to the individual patient's tumor biology and functional status.

  • Collaborate with an interdisciplinary team, including oncologists, radiologists, and pathologists, to ensure a holistic and coordinated approach to Krukenberg tumor management.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Physicians and Physician Associates: StatPearls, LLC designates this enduring material for a maximum of 1.00 AMA PRA Category 1 Credit(s)TM. Physicians and PAs should only claim credit commensurate with the extent of their participation in the activity.

American Board of Anesthesiology: This activity contributes to the CME component of the American Board of Anesthesiology’s redesigned Maintenance of Certification in AnesthesiologyTM (MOCA®) program, known as MOCA 2.0®. Please consult the ABA website, www.theABA.org, for a list of all MOCA 2.0 requirements.

American Board of Internal Medicine: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.00 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

American Board of Pathology: Successful completion of this Continuing Certification activity, which includes participation in the evaluation component, enables the participant to earn up to 1.00 Lifelong Learning (CME) credits in the American Board of Pathology’s Continuing Certification Program.

American Board of Surgery: Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn credit toward the CME and Self-Assessment requirement(s) of the American Board of Surgery’s Continuous Certification program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABS credit.

Royal College of Physicians and Surgeons of Canada: Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Michael B. on 11/30/2021

Ron H. on 4/28/2023

Henry X. on 3/18/2024

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