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Optic Nerve Coloboma

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  Optic Nerve Coloboma

Credits: 1.00   Post-Assessment Questions:  5

Release Date: 5 Oct 2020
Expiration Date: 30 Jun 2021
Last Reviewed: 30 Jun 2020
Estimated Time To Finish: 60 Minutes

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Activity Description

The term coloboma derives from the Greek word koloboma, originally used to indicate a part that was removed by mutilation, missing or cut short. Colobomas are congenital ocular defects that can affect the iris, the lens, the choroid, the retina, and the optic nerve. Optic nerve colobomas have been associated with microphthalmos, iris coloboma, ciliary coloboma, lens notching, retinal detachment, neovascular membranes, and macular holes. Optic nerve colobomas have been associated with microphthalmos, iris coloboma, ciliary coloboma, lens notching, retinal detachment, neovascular membranes, and macular holes. On a typical funduscopic exam, clinicians see large optic nerve excavations usually inferiorly. Defects occur both unilaterally and bilaterally at equal rates. Patients may have microphthalmia or optic nerve cysts that communicate with the subarachnoid space. Cysts rarely expand to cause compressive optic neuropathy. Optic nerve hypoplasia is a more common cause of visual impairment in children than optic nerve coloboma. Bilateral disease is more common than unilateral disease. The former presents with nystagmus, whereas the latter presents with strabismus. Visual acuity can range from 20/20 to NLP. On examination the optic nerve is small.Iris colobomas may cause photophobia, visual distortion and double vision. They may also be cosmetically unacceptable. Cosmetic contact lenses with an artificial pupil may be used. Surgical repair of the defect with sutures may be possible. Artificial iris prosthetic devices are being explored in the presence of pseudophakia. Iris-painted intraocular lenses may be implanted after removal of the cataract. Foldable artificial irises may also be inserted through a small incision. This activity reviews the evaluation and treatment of optic nerve coloboma and the role of the interprofessional team in managing this condition.

Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Describe the pathophysiology of optic nerve colobomas.
  • Review the presentation of a patient with an optic nerve coloboma.
  • Summarize the treatment of an optic nerve coloboma.

Author(s) / Contributors Disclosure of Conflicts of Interest

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.


Hover over the contributor names to see details and disclosures of any financial relationships or relationships they or their spouse/life partner have with commercial interests related to the content of this continuing education activity.

Authors: Sravanthi Vegunta
Editors: Bhupendra Patel
Editors-In-Chief: Jim WangShane HavensKoushik Tripathy
Chief Medical Reviewer: Mahdi Alsaleem
Nurse Planner/Reviewer/Editor: Lisa Haddad
Nurse Planner/Reviewer/Editor: Bernadette Makar
Nurse Planner/Reviewer/Editor: Dorothy Caputo
Pharmacy Planner/Reviewer/Editor: Mark Pellegrini
Physician Planner/Reviewer/Editor: Scott Dulebohn

Continuing Education Accreditation Information

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.00 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.


Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

  • If you have content or system concerns, please contact support@statpearls.com, or call 727-289-9796.
  • If you have activity or credit concerns, please contact guy@campbell.edu, or call 910-893-7960.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

Media Usage Rights

The contributors and editors of StatPearls have attested that all associated media (images and video) have been legally cleared for use with this activity.  All copyrights are reserved.

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