Antiemetic Neurokinin-1 Receptor Blockers

Overview

4.3 out of 5 (30 Reviews)

Credits

1.00

Post Assessment Questions

6

Start Date

1 Jan 2021

Last Review Date

11 Jan 2024

Expiration Date

31 Dec 2023

Estimated Time To Finish

60 Minutes


 
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Activity Description

Neurokinin-1 (NK-1) receptor antagonists are antiemetic drugs with unique anxiolytic, antidepressant, and antiemetic properties. The discovery of NK-1 receptor blockers was crucial in preventing emesis associated with cancer chemotherapy. The NK-1 receptor antagonist competitively binds to the NK-1 receptor, thereby blocking the binding of substance P and preventing the transmission of the emetic signal. This activity reviews the indications, contraindications, mechanism of action, adverse event profile, and other crucial aspects of antiemetic NK-1 receptor blockers within the clinical setting. This activity also focuses on essential information required by members of an interprofessional team responsible for treating patients who stand to benefit therapeutically from these agents.


Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify appropriate candidates for neurokinin-1 receptor antagonists based on their understanding of the patient's chemotherapy regimen and emetogenic risk.

  • Apply knowledge of neurokinin-1 receptor antagonists in diverse clinical scenarios, tailoring treatment approaches to individual patient needs and characteristics.

  • Select the most appropriate neurokinin-1 receptor antagonist based on patient-specific factors, treatment goals, and potential drug interactions.

  • Collaborate with other interprofessional healthcare teams, such as pharmacists and nurses, optimizing the use of neurokinin-1 receptor antagonists to achieve the best outcomes in managing chemotherapy-induced nausea and vomiting.

       

Disclosures

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Continuing Education Accreditation Information

 

 

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.00 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

 

 
 

Reviews

Laura C. on 6/25/2021

Christopher C. on 8/30/2021

Suzanne P. on 3/1/2022

Zoe M. on 7/26/2022

Kari B. on 8/5/2022

Nice

Kenneth R. on 11/2/2022

Anna B. on 12/3/2022

Lauren K. on 12/5/2022

Peter S. on 1/4/2023

Scott C. on 1/14/2023

Dakota P. on 2/15/2023

Russell R. on 3/1/2023

James S. on 3/25/2023

Deanne N. on 4/15/2023

shahid i. on 8/19/2023

Good CME series

Douglas B. on 9/2/2023

Kira M. on 9/8/2023

Richard D. on 9/23/2023

Genevieve M. on 10/11/2023

Essam M. on 10/21/2023

Ann C. on 10/30/2023

ROBERT Z. on 12/20/2023

Hedy M. on 12/29/2023

Tina S. on 1/16/2024

Steven F. on 1/21/2024

Kelly K. on 2/10/2024

Elizabeth B. on 3/14/2024

karin p. on 3/22/2024

Maren E. on 4/12/2024

Theresa J. on 4/15/2024

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