Acute Lymphocytic Leukemia

Overview

4.5 out of 5 (106 Reviews)

Credits

1.50

Post Assessment Questions

8

Start Date

1 Jan 2021

Last Review Date

26 Aug 2023

Expiration Date

31 Dec 2023

Estimated Time To Finish

90 Minutes


 
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Activity Description

Acute lymphocytic leukemia (ALL) is a malignancy of B or T lymphoblasts characterized by uncontrolled proliferation of abnormal, immature lymphocytes and their progenitors which ultimately leads to the replacement of bone marrow elements and other lymphoid organs resulting in a characteristic disease pattern. ALL accounts for approximately 2 percent of lymphoid neoplasms in the United States and occurs slightly more frequently in males than females and three times as frequently in Caucasians as in African Americans. Patients typically present with symptoms related to anemia, thrombocytopenia, and neutropenia due to the replacement of the bone marrow with the tumor. Symptoms can include fatigue, easy or spontaneous bruising and/or bleeding, and infections. Additionally, B-symptoms, such as fever, night sweats, and unintentional weight loss, are often present but may be mild, and hepatomegaly, splenomegaly, and lymphadenopathy can be seen in up to half of adults on presentation. Central nervous system (CNS) involvement is common and can be accompanied by cranial neuropathies or symptoms, predominantly meningeal, related to increased intracranial pressure. This activity examines when acute lymphocytic leukemia should be considered on differential diagnosis and how to properly evaluate it. This activity highlights the role of the interprofessional team in caring for patients with this condition.


Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the epidemiology of acute lymphocytic leukemia.

  • Outline the exam findings typically seen in patients with acute lymphocytic leukemia.

  • Review the management of acute lymphocytic leukemia.

  • Explain modalities to improve care coordination among interprofessional team members in order to improve outcomes for patients affected by acute lymphocytic leukemia.

Disclosures

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Continuing Education Accreditation Information

 

 

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.50 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

 

 
 

Reviews

Henrik H. on 2/8/2021

ayodeji a. on 7/15/2021

Larry M. on 7/18/2021

Christopher C. on 8/1/2021

Rene W. on 8/27/2021

Amal A. on 9/4/2021

Kelli B. on 9/27/2021

MOSFER A. on 9/4/2022

Harry A. on 10/17/2021

on 12/27/2021

Tiffany N. on 2/5/2022

Timothy M. on 2/16/2022

Jennifer K. on 2/25/2022

Anne C. on 3/3/2022

Jessica B. on 3/7/2022

Tamara L. on 3/14/2022

Surabhi C. on 3/23/2022

Dr.Mallikarjun K. on 5/1/2022

Christine U. on 5/6/2022

PATIENCE A. on 5/18/2022

sherman y. on 5/30/2022

Shannon j. on 6/27/2022

Rohit A. on 7/4/2022

Amelia B. on 10/5/2022

Theodore B. on 10/25/2022

Sara M. on 10/28/2022

Stephanie K. on 11/4/2022

Dr Jagveer S. on 11/9/2022

Lindsey M. on 11/19/2022

Good info

Kenneth R. on 11/27/2022

Vektra C. on 12/26/2022

Ronald L. on 1/28/2023

Christy M. on 2/28/2023

Ahmmed A. on 3/5/2023

Robert F. on 3/7/2023

Akshaya K. on 4/4/2023

Daniel H. on 4/11/2023

Matthew N. on 4/16/2023

Alexander W. on 4/24/2023

Michael R. on 5/21/2023

cynthia s. on 6/11/2023

Adithya nikhileshwar B. on 6/13/2023

Sean K. on 6/26/2023

Ashley W. on 6/30/2023

Susan f. on 7/4/2023

Cerise M. on 7/7/2023

Kelly K. on 7/10/2023

Samantha P. on 7/26/2023

kimberly g. on 8/8/2023

Grace A. on 8/9/2023

Joshua K. on 8/19/2023

no abnormal cytogenetics are not necessarily a good prognosis since there are prognostically positive cytogenetic abnormalities.

Diana S. on 8/22/2023

Steven S. on 9/8/2023

Chris C. on 9/9/2023

Dr Sruthi G. on 9/20/2023

Essam M. on 9/18/2023

Tanya H. on 9/29/2023

Thanks

Matthew C. on 10/2/2023

Richard C. on 10/8/2023

Sushma B. on 10/13/2023

Liam M. on 10/19/2023

Karamo C. on 10/21/2023

Daniel I. on 10/24/2023

Kody S. on 10/30/2023

Nivetha V. on 11/11/2023

Donna P. on 11/15/2023

Likta N. on 12/7/2023

Great review.

Richard P. on 12/10/2023

Hawabu S. on 12/12/2023

Scott S. on 12/18/2023

Waldo F. on 12/21/2023

Information was not provided in the information about ALL to answer the initial question (with Tdt in answer) or the question with xanthine oxidase in the answer. The questions would be fine if the information were included in the educational information about ALL.

Mary S. on 12/28/2023

francisco B. on 12/28/2023

Melissa W. on 12/28/2023

Mary H. on 12/28/2023

Cherie T. on 12/28/2023

Steven L. on 12/29/2023

Meredith G. on 12/31/2023

Sushma B. on 1/3/2024

BRANDI B. on 1/5/2024

Maria N. on 1/7/2024

Lori M. on 1/23/2024

shazia z. on 1/24/2024

Ambreen S. on 1/25/2024

Vonda R. on 1/26/2024

Kerry W. on 1/31/2024

john d. on 1/31/2024

Erin M. on 2/10/2024

Stacey S. on 2/18/2024

shahid m. on 2/28/2024

Gardenia Z. on 3/7/2024

Tyler J. on 3/10/2024

Malani K. on 3/11/2024

Randall W. on 3/14/2024

Yashma P. on 3/17/2024

Mark K. on 3/17/2024

Maureen H. on 3/18/2024

Kathryn H. on 3/20/2024

Luis P. on 3/21/2024

Yago N. on 3/27/2024

Julie C. on 4/3/2024

Nathan S. on 4/4/2024

Tiffany M. on 4/5/2024

Stacy T. on 4/5/2024

David R. on 4/6/2024

Yashpal m. on 4/7/2024

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