Pharmacy-Applied Toxicology CE

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About StatPearls CE

All of our activities are approved by ACPE (PharmD) and all activity is reported to CE Broker and all states as required. StatPearls continuing education activities are linked to practice questions which are based on the American Board of Applied Toxicology (ABAT)®, American Board of Toxicology (ABT)®, American Osteopathic Board of Emergency Medicine®, American Board of Emergency Medicine® content outlines. 646 authors and 17 editors have contributed to the development of the Pharmacy-Applied Toxicology content, which is continuously refined and updated to improve your learning experience.

Pharmacy-Applied Toxicology Activities

Title Description Hours Questions
3,4-Methylenedioxy-Methamphetamine This activity reviews the class 1 drug 3,4 - methylenedioxymethamphetamine, also known as MDMA, Ecstacy or Molly. The drug is known to promote a sens ... Read the Article 1 6 Activity Info
Acanthosis Nigricans Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in in skin folds, such as the back of the neck, axil ... Read the Article 1.25 10 Activity Info
Acarbose Type 2 diabetes mellitus is a growing concern around the world, and in the USA in particular, with clinicians encountering the condition more frequent ... Read the Article 1 7 Activity Info
Acetaminophen Many diseases and conditions list pain as a component of their presentation; as a result, pain management is of great importance to both clinicians an ... Read the Article 1.25 8 Activity Info
Acetaminophen Toxicity Acetaminophen toxicity is the second most common cause of liver transplantation worldwide and the most common cause of liver transplantation in the US ... Read the Article 1.25 9 Activity Info
Acetaminophen/Aspirin/Caffeine The FDA recognized the combination of acetylsalicylic acid (250 mg), acetaminophen (250 mg), and caffeine (65 mg) as safe and effective in treating ac ... Read the Article 1 6 Activity Info
Acetylcholinesterase Inhibitors Toxicity Nerve agents are some of the most deadly and easily employed chemical warfare agents. Given the global threat of terrorism, it is prudent to have a ba ... Read the Article 1.25 8 Activity Info
Achlorhydria Achlorhydria is a condition in which the stomach does not produce hydrochloric acid, one of the components of gastric acid. Hydrochloric acid plays an ... Read the Article 1 7 Activity Info
Acitretin Acitretin belongs to a group of drugs known as retinoids. Retinoids include natural and synthetic compounds that have similar activity to vitamin A. V ... Read the Article 1 7 Activity Info
Acromegaly Acromegaly is a disorder caused by excessive production of growth hormone from the anterior pituitary gland, resulting in excessive growth of body tis ... Read the Article 1.25 12 Activity Info
Activated Charcoal An oral suspension of activated charcoal should be considered in poisonings when gastrointestinal decontamination of an ingested toxin is indicated. A ... Read the Article 1 5 Activity Info
Acute Hepatitis Acute hepatitis is a term used to describe a wide variety of conditions characterized by acute inflammation of the hepatic parenchyma or injury to hep ... Read the Article 1.25 7 Activity Info
Acute Kidney Injury Acute kidney injury, previously known as acute renal failure, denotes a sudden and often reversible reduction in the kidney function, as measured by ... Read the Article 1.5 16 Activity Info
Acute On Chronic Liver Failure Acute on chronic liver failure is a clinical syndrome of sudden hepatic decompensation observed in patients with pre-existing chronic liver disease. A ... Read the Article 1 6 Activity Info
Adalimumab Adalimumab is a fully human, high-affinity, recombinant anti-tumor necrosis factor (TNF) alpha monoclonal antibody, used to treat rheumatoid arthritis ... Read the Article 1.25 10 Activity Info
Addiction The laymen's definition of addiction is a "fact or condition of being addicted to a particular substance, thing, or activity." Medically it is a "chro ... Read the Article 1.25 9 Activity Info
Addiction Relapse Prevention Individuals recovering from various forms of addiction frequently encounter relapses that have gained acceptance as an almost inevitable part of the r ... Read the Article 1.25 8 Activity Info
Adenosine Adenosine has uses as both a diagnostic or therapeutic agent. As a diagnostic agent, adenosine can be utilized in myocardial perfusion stress imaging ... Read the Article 1.25 9 Activity Info
Albuterol Albuterol is used for the treatment and prevention of bronchospasm (acute or severe) in patients with reversible obstructive airway disease. It also h ... Read the Article 1.25 8 Activity Info
Alcohol Related Psychosis Psychosis associated with alcohol can occur with acute intoxication, alcohol withdrawal, and chronic alcoholism. Alcohol-related psychosis is also kno ... Read the Article 1 6 Activity Info
Alcohol Withdrawal Alcohol withdrawal symptoms usually appear when an individual discontinues or reduces alcohol intake after a period of prolonged consumption. In most ... Read the Article 1.25 9 Activity Info
Alkali Toxicity Alkali toxicity, though rare, can lead to serious medical problems. Adult caustic ingestions are usually intentional, involving more substantial amou ... Read the Article 1 4 Activity Info
Alpha Receptor Agonist Toxicity Alpha-adrenergic agonist toxicity is due to a broad group of pharmaceutical agents known as alpha agonists, which can be further broken down into cent ... Read the Article 1 4 Activity Info
Alprazolam Alprazolam, known by various trade names, is the most commonly prescribed psychotropic medication in the United States. Alprazolam is frequently presc ... Read the Article 1 5 Activity Info
Aluminum Hydroxide Aluminum hydroxide is a medication used in the management and treatment of acid indigestion. It is in the antacid class of drugs. This activity outlin ... Read the Article 1 7 Activity Info
Amantadine Amantadine is an antiviral agent with mild antiparkinsonian activity. Amantadine was used in the early 2000s for Influenza A treatment. However, high ... Read the Article 1 6 Activity Info
Amatoxin Mushroom Toxicity Amatoxin containing mushrooms are a rare but significant cause of acute fulminant liver failure. However, not all Amanita species have this toxin, and ... Read the Article 1 4 Activity Info
Aminoglycosides While aminoglycosides are an older class of medication, they continue to be clinically valuable. Aminoglycosides have a broad spectrum of activity cov ... Read the Article 1 8 Activity Info
Aminophylline Aminophylline is FDA approved for the treatment of reversible airway obstruction due to asthma or other chronic lung diseases. This activity illustrat ... Read the Article 1 5 Activity Info
Amitriptyline Amitriptyline is FDA approved medication to treat depression in adults. The Non-FDA approved indications are anxiety, post-traumatic stress disorder, ... Read the Article 1 7 Activity Info
Ammonia Toxicity Ammonia toxicity occurs when susceptible individuals suffer exposure to external sources of ammonia via ingestion, inhalation, direct contact with ski ... Read the Article 1 4 Activity Info
Amoxapine Amoxapine is an FDA approved drug belonging to the class of second-generation tricyclic dibenzoxazepine antidepressants. Generally, it is reserved for ... Read the Article 1 6 Activity Info
Amphetamine Amphetamine is a medication used in the management and treatment of ADHD and narcolepsy. It is classified as a central nervous system stimulant. This ... Read the Article 1 5 Activity Info
Amphetamine Related Psychiatric Disorders Amphetamines belong to a class of compounds called phenethylamines which induce catecholaminergic effects in the CNS and peripheral circulation. Recre ... Read the Article 1 6 Activity Info
Amphetamine Toxicity Amphetamine abuse is widespread, and overdose is associated with significant and negative impacts on the cardiovascular and neurological systems. Pati ... Read the Article 1 6 Activity Info
Amphotericin B Amphotericin B deoxycholate belongs to the polyene class of antifungals. It is also known by the name conventional amphotericin B and has been used fo ... Read the Article 1 7 Activity Info
Anabolic Steroid Toxicity Anabolic steroids such as testosterone are produced naturally and enhance protein synthesis at the cellular level. There are also synthetic analogs av ... Read the Article 1 4 Activity Info
Anabolic Steroid Use Disorder Androgen use has become a major public health concern due to the transition of use of androgens from strictly sports to a much wider spectrum of the ... Read the Article 1 4 Activity Info
Angiotensin II Angiotensin is a peptide endocrine hormone and an important part of the renin-angiotensin-aldosterone system, an inter-related endocrine system import ... Read the Article 1.25 8 Activity Info
Anthracycline Medications (Doxorubicin) Doxorubicin is an anthracycline class medication used in the management and treatment of various types of malignancies and tumors. This activity will ... Read the Article 1 5 Activity Info
Antiarrhythmic Medications The antiarrhythmic medications have typically been categorized according to the Vaughan-Williams (VW) classification system. The system classifies the ... Read the Article 1.25 11 Activity Info
Anticholinergic Medications Anticholinergic medications are used in the management and treatment of a wide range of diseases. This activity illustrates the indications, action, ... Read the Article 1.25 10 Activity Info
Anticholinergic Toxicity Anticholinergic toxicity is commonly seen in the emergency department but is rarely fatal. According to the 2015 annual American Association of Poison ... Read the Article 1 7 Activity Info
Anticoagulation Safety One class of drugs that has been implicated in serious adverse drugs reactions for many decades are the oral anticoagulants, especially warfarin. Ther ... Read the Article 1.25 7 Activity Info
Anticonvulsants Toxicity Anticonvulsants, or antiepileptics, are an ever-growing class of medications that act through multiple different mechanisms to control seizures. Antie ... Read the Article 1 4 Activity Info
Antidotes Overdoses and accidental ingestions or exposures are common throughout the world. With more than 2.4 million toxic exposures each year, poisoning is ... Read the Article 1 5 Activity Info
Antiemetic Antimuscarinics Scopolamine is a medication used in the management and treatment of motion sickness and postoperative nausea/vomiting. It is in the antimuscarinic cla ... Read the Article 1 7 Activity Info
Antiemetic Histamine H1 Receptor Blockers First-generation antihistamines have several indications that primarily include nausea and vomiting secondary to motion sickness and vertigo, but seco ... Read the Article 1 5 Activity Info
Antiemetic Neurokinin-1 Receptor Blockers Neurokinin-1 (NK-1) receptor antagonists are a new class of antiemetic drugs that possess unique anxiolytic, antidepressant, and antiemetic properties ... Read the Article 1 6 Activity Info
Antihistamine Toxicity In 1943, as the planet was engulfed in WWII and the United States was officially announcing the end of The Great Depression, the most common modern an ... Read the Article 1 4 Activity Info
Anti-NMDA Receptor Encephalitis In Children Anti NMDA receptor encephalitis is commonly confused with schizophrenia. Most of the available data on this illness is through published case reports. ... Read the Article 1 5 Activity Info
Antiplatelet Drug Toxicity Antiplatelet medications are primarily used for the management and prevention of cardiovascular disease (CVD) related events. Currently, there are fou ... Read the Article 1 5 Activity Info
Antipsychotic Medications First-generation antipsychotics are dopamine receptor antagonists (DRA) and are known as typical antipsychotics. Second-generation antipsychotics are ... Read the Article 1.25 8 Activity Info
Antisialagogues Antisialagogues are medications often used in the management and treatment of patients with noisy breathing near the end of life. These medications ar ... Read the Article 1 5 Activity Info
Anxiolytics and Sedative-Hypnotics Toxicity Anxiolytics and sedative-hypnotics are widely consumed at home and in a hospital setting. This activity reviews the most commonly used agents of these ... Read the Article 1 7 Activity Info
Aromatic Toxicity Hydrocarbons are organic compounds consisting of carbon and hydrogen atoms. Toluene and benzene can be found in products such as gasoline, nail polis ... Read the Article 1 5 Activity Info
Arrhythmias Arrhythmia entails a broad spectrum of disorders of heart rate and rhythm abnormalities. Arrhythmia is broadly categorized into bradyarrhythmias and t ... Read the Article 1 6 Activity Info
Arsenic Toxicity Arsenic poisoning is a global health issue affecting millions of people worldwide through environmental and occupational exposure, as well as intentio ... Read the Article 1.25 8 Activity Info
Atenolol Atenolol is a second-generation beta-1-selective adrenergic antagonist indicated in the treatment of hypertension, angina pectoris, and acute myocardi ... Read the Article 1 5 Activity Info
Atomoxetine Atomoxetine is indicated for the treatment of attention deficit hyperactivity disorder (ADHD) in adults and children over the age of 6. Although atomo ... Read the Article 1.25 9 Activity Info
Atrial Fibrillation Atrial fibrillation is the most common type of cardiac arrhythmia. It is the leading cardiac cause of stroke. Risk factors for atrial fibrillation inc ... Read the Article 2 29 Activity Info
Atrioventricular Dissociation Atrioventricular dissociation is a cardiac conduction defect where the atria and ventricles beat independently of each other. It can occur due to vari ... Read the Article 1 5 Activity Info
Atropine Atropine or atropine sulfate carries FDA indications for anti-sialagogue/anti-vagal effect, organophosphate/muscarinic poisoning, and bradycardia. Atr ... Read the Article 1.25 11 Activity Info
Auditory Hallucinations Auditory hallucinations are the sensory perceptions of hearing noises without an external stimulus. This symptom is particularly associated with schiz ... Read the Article 1 5 Activity Info
Autonomic Pharmacology The basis of autonomic pharmacology reflects the physiology of the sympathetic nervous system (SNS) and the parasympathetic nervous system (PSNS) to r ... Read the Article 1 5 Activity Info
Azathioprine Azathioprine (AZA) is a medication used in the management and treatment of active rheumatoid arthritis (RA) and the prevention of kidney transplant r ... Read the Article 1 5 Activity Info
Baclofen Baclofen is used to treat muscle spasticity; it is FDA-approved for the management of reversible spasticity, particularly for the relief of flexor spa ... Read the Article 1 6 Activity Info
Barbiturate Toxicity Barbiturates are a class of sedative-hypnotic drugs. They are commonly used as antiepileptics (phenobarbital) and for the induction of general anesthe ... Read the Article 1 5 Activity Info
Barbiturates Barbiturates are a group of sedative-hypnotic medications used for the treatment of seizure disorder, neonatal withdrawal, insomnia, preoperative anxi ... Read the Article 1 4 Activity Info
Benzocaine Benzocaine is a local anesthetic used in the management of pain control. It is in the ester local anesthetic class of medications. This activity descr ... Read the Article 1 5 Activity Info
Benzodiazepine Toxicity Since the 1960s, with the development of chlordiazepoxide and shortly thereafter diazepam, benzodiazepines quickly became popular medications secondar ... Read the Article 1.25 9 Activity Info
Benzodiazepines Benzodiazepines are especially important in the cessation of seizure activity, as 1% to 2% of emergency department visits annually in the United State ... Read the Article 1 4 Activity Info
Benztropine Benztropine is FDA approved as adjunctive therapy for all forms of parkinsonism. It is also used for drug-induced extrapyramidal symptoms and the prev ... Read the Article 1 5 Activity Info
Berylliosis Berylliosis, also known as chronic beryllium disease (CBD), is a granulomatous disease caused by exposure to beryllium. CBD has a variable clinical co ... Read the Article 1 4 Activity Info
Beta 2 Agonists Beta-2 adrenergic receptor agonists are a class of medications used in the frontline management and treatment of bronchial asthma and COPD. This activ ... Read the Article 1 5 Activity Info
Beta 2 Receptor Agonists/Antagonists Beta-2 adrenergic receptors are cell-surface receptors clinically taken advantage of in the management of bronchospasm as in patients with bronchial a ... Read the Article 1 5 Activity Info
Beta-Blocker Toxicity Beta-blockers antagonize beta-adrenergic receptors and are used mainly in the treatment of hypertension, heart failure, tachydysrhythmias, and angina ... Read the Article 1 5 Activity Info
Bethanechol Bethanechol is FDA approved for the treatment of postoperative urinary retention, postpartum urinary retention, and overflow incontinence caused by ne ... Read the Article 1.25 9 Activity Info
Biologic Warfare Agent Toxicity Biological warfare agents include bacteria, viruses, fungi, and biological toxins. Some agents are frequently lethal while others are intended to caus ... Read the Article 1.25 8 Activity Info
Biologic, Chemical, and Radiation Terrorism Review Terrorism is the intentional use of indiscriminate violence to create fear and terror as a means to achieve an ideological, financial, religious, or p ... Read the Article 1.5 10 Activity Info
Bisoprolol Bisoprolol is a medication used in the management and treatment of hypertension and congestive heart failure. It is in the selective beta-blocker clas ... Read the Article 1 5 Activity Info
Bisphosphonate Bisphosphonates define a class of drugs that are widely indicated since the 1990s to treat osteoporosis both in men and women. Their effectiveness in ... Read the Article 1.25 12 Activity Info
Bisphosphonate Related Jaw Osteonecrosis Bisphosphonates are synthetic pyrophosphate analogs used to treat hypercalcemia secondary to conditions affecting bone resorption such as malignancy, ... Read the Article 1.25 8 Activity Info
Bisphosphonate Toxicity In the second half of the 20th century, bisphosphonates have emerged as a novel treatment for bone metabolism disorders. Currently, bisphosphonates ar ... Read the Article 1 7 Activity Info
Bleach Toxicity Bleach refers to a large class of compounds used to whiten or color-lighten materials. They are frequently used for cleaning and disinfection; bleache ... Read the Article 1 4 Activity Info
Blister Agents Sulfur mustard (dichlorethylsulphide) and nitrogen mustard are blistering agents, or vesicants, that have been used in chemical warfare since before t ... Read the Article 1.25 9 Activity Info
Bosentan Pulmonary artery hypertension has proven to cause significant mortality and morbidity worldwide. The first-line treatment option for pulmonary artery ... Read the Article 1 7 Activity Info
Botulinum Toxin Botulinum toxin is a medication used in the management and treatment of therapeutic and cosmetic purposes. Therapeutic uses include chronic migraine, ... Read the Article 1 7 Activity Info
Botulism Botulism is a rare, potentially fatal syndrome of diffuse, flaccid paralysis caused by botulinum neurotoxin (BoNT) which is elaborated by the bacteriu ... Read the Article 1.5 17 Activity Info
Botulism Antitoxin Botulinum antitoxin, also known as botulism antitoxin, is comprised of antibodies or antibody antigen-binding fragments that block the neurotoxin prod ... Read the Article 1 5 Activity Info
Brexanolone Brexanolone is a medication used in the treatment of postpartum depression in adult women. It is in the GABA-A modulator class of medications. This ac ... Read the Article 1 5 Activity Info
Bronchoalveolar Lavage Bronchoalveolar Lavage or BAL is a minimally invasive procedure that involves instillation of sterile normal saline into a subsegment of the lung, fol ... Read the Article 1 4 Activity Info
Butterbur Butterbur (derived from the leaves of Petasites japonicus) is an herbal supplement that has been found to be effective in the prophylaxis of adult mig ... Read the Article 1 5 Activity Info
Cadmium Toxicity Cadmium is a heavy metal that causes direct harm to humans in several forms. It is regularly found with other heavy metals such as zinc, copper, and ... Read the Article 1 5 Activity Info
Caffeine Caffeine is a naturally occurring, central nervous system (CNS) stimulant of the methylxanthine class and is the most widely taken psychoactive stimul ... Read the Article 1 6 Activity Info
Caffeine Toxicity Caffeine is a stimulant that has been utilized globally for centuries secondary to its ability to improve mental alertness. As many as 85% of American ... Read the Article 1 6 Activity Info
Caffeine Withdrawal Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class and is one of the most widely used drugs in the world. Unlike other p ... Read the Article 1 5 Activity Info
Calcineurin Inhibitors Calcineurin inhibitors (CNI) are composed of three drugs (cyclosporine, tacrolimus, and pimecrolimus). They are primarily used as immunosuppressive dr ... Read the Article 1 5 Activity Info
Calcium Channel Blocker Toxicity Calcium channel blockers (CCBs) are among the most commonly used cardiovascular drugs in the adult population. Like most other medications, when calci ... Read the Article 1 5 Activity Info
Calcium Channel Blockers Calcium channel antagonists, also known as calcium channel blockers (CCBs), have been widely used for many indications. These agents are often classif ... Read the Article 1 5 Activity Info
Cancer Chemotherapy Chemotherapy in cancer has merged the disease course from a terminal and catastrophic result in merely all cases to a treatable and sometimes curable ... Read the Article 1.75 24 Activity Info
Cannabinoid Toxicity Cannabinoids are a collective group of compounds that act on cannabinoid receptors. They include plant-derived phytocannabinoids, synthetic cannabinoi ... Read the Article 1 6 Activity Info
Cannabis Use Disorder Cannabis use can cause intoxication, withdrawal, and biopsychosocial issues. This activity describes the evaluation and management of cannabis use dis ... Read the Article 1.25 6 Activity Info
Cannaboinoid Antiemetic Therapy There are currently three cannabinoids available on the pharmaceutical market. Dronabinol and nabilone are both synthetic tetrahydrocannabinol (THC) ... Read the Article 1 5 Activity Info
Carbamate Toxicity Carbamates are a class of insecticides structurally and mechanistically similar to organophosphate (OP) insecticides. Carbamates are N-methyl Carbamat ... Read the Article 1 4 Activity Info
Carbamazepine Carbamazepine is used in the management and treatment for epilepsy, trigeminal neuralgia, and acute manic and mixed episodes in bipolar I disorder. In ... Read the Article 1.25 10 Activity Info
Carbamazepine Toxicity Carbamazepine is a commonly prescribed agent for focal epilepsy and other nonepileptic conditions such as neuropathic pain, schizophrenia, and bipolar ... Read the Article 1.25 8 Activity Info
Carbon Dioxide Narcosis Carbon dioxide (CO2) narcosis is a condition that develops when excessive CO2 is present in the bloodstream, leading to a depressed level of conscious ... Read the Article 1 5 Activity Info
Carbon Monoxide Toxicity Carbon monoxide toxicity occurs after breathing in excessive levels of carbon monoxide. This is a tasteless, odorless, and colorless gas and victims a ... Read the Article 1.5 14 Activity Info
Carbon Tetrachloride Toxicity Carbon tetrachloride (CCl4) is an important agent for multiple purposes, such as cleaning purposes, industrial agents, etc. But it can cause several a ... Read the Article 1 5 Activity Info
Carboxyhemoglobin Toxicity Carbon monoxide is a tasteless, odorless, colorless, and non-irritating gas formed with the incomplete combustion of hydrocarbons (fossil fuels). It i ... Read the Article 1 6 Activity Info
Cardioactive Steroid Toxicity Cardioactive steroids (CAS) are medically important compounds historically used for conditions like edema and "dropsy." They are available in several ... Read the Article 1 5 Activity Info
Carisoprodol Carisoprodol is an FDA-approved drug indicated for the relief of discomfort associated with acute, painful musculoskeletal conditions. Although market ... Read the Article 1 4 Activity Info
Caspofungin Caspofungin is a drug in the echinocandins class of medications, used in the management and treatment of several medical conditions. These conditions ... Read the Article 1 5 Activity Info
Castor Oil Castor oil is a vegetable oil made from Ricinus communis, a plant common in the Eastern areas of the world. Castor oil is most well known for its laxa ... Read the Article 1.25 10 Activity Info
Cataplexy Cataplexy, a physical feature of narcolepsy, is characterized by transient episodes of voluntary muscle weakness precipitated by intense emotion. Subj ... Read the Article 1 7 Activity Info
Central Pontine Myelinolysis Central pontine myelinolysis is a rare neurologic condition most frequently caused by the rapid correction of hyponatremia. This activity reviews the ... Read the Article 1.25 9 Activity Info
Cephalexin Cephalexin is an FDA approved antibiotic. Cephalexin is a first-generation cephalosporin utilized in the treatment of urinary tract infections, respir ... Read the Article 1 5 Activity Info
Change In Mental Status Altered mental status is a common presentation. It is important to recognize the early signs of altered mental status, identify the underlying cause, ... Read the Article 1 2 Activity Info
Chemical Burns Healthcare professionals should be knowledgeable about chemical burns from exposure to acids (pH less than 7), alkalis (pH greater than 7), and irrita ... Read the Article 1 5 Activity Info
Chloramphenicol Chloramphenicol is a medication used in the management and treatment of superficial eye infections such as bacterial conjunctivitis, and otitis extern ... Read the Article 1 7 Activity Info
Chlordiazepoxide Chlordiazepoxide is a long-acting benzodiazepine and is an FDA approved medication for adults with mild-moderate to severe anxiety, preoperative anxie ... Read the Article 1 6 Activity Info
Chlorine Gas Toxicity Gaseous chlorine is poisonous and classified as a pulmonary irritant. It has intermediate water solubility with the capability of causing acute damage ... Read the Article 1 5 Activity Info
Chloroquine Chloroquine is a medication used in the management and treatment of malaria and inflammatory diseases. It is in the sulfonamides class of drugs. This ... Read the Article 1 6 Activity Info
Chloroquine And Hydroxychloroquine Toxicity Chloroquine or hydroxychloroquine, a less toxic metabolite of chloroquine, can cause pathologic ocular damage unless strict prescribing and screening ... Read the Article 1.25 8 Activity Info
Chlorpromazine Chlorpromazine is a medication used in the management and treatment of schizophrenia, bipolar disorder, and acute psychosis. It is in the category of ... Read the Article 1.25 8 Activity Info
Cholestatic Jaundice Cholestasis is defined as stagnation, or at least a marked reduction, in bile secretion and flow. Cholestasis can be due to a functional impairment of ... Read the Article 1 6 Activity Info
Cholinergic Crisis A cholinergic crisis develops as a result of overstimulation of nicotinic and muscarinic receptors at the neuromuscular junctions. This is usually sec ... Read the Article 1 6 Activity Info
Cholinergic Toxicity Cholinergic toxicity is caused by substances that stimulate, enhance or mimic the neurotransmitter acetylcholine, the primary neurotransmitter of the ... Read the Article 1 6 Activity Info
Cholinesterase Inhibitors Cholinesterase inhibitors function to decrease the breakdown of acetylcholine. They SEe use in the treatment of Alzheimer and dementia symptoms. This ... Read the Article 1.25 11 Activity Info
Chronic Pain Over one-quarter of United States citizens suffer from chronic pain. It is among the most common complaints seen in an outpatient clinic. The failure ... Read the Article 2.75 43 Activity Info
Chronic Renal Failure Chronic kidney disease (CKD) is defined as the presence of kidney damage or an estimated glomerular filtration rate (eGFR) less than 60 ml/min per 1.7 ... Read the Article 1.75 20 Activity Info
Ciguatera Toxicity Ciguatera toxicity is a food-borne illness caused by eating fish contaminated with Ciguatoxin. This toxin is a potent neurotoxin, and it is produced b ... Read the Article 1 4 Activity Info
Clomipramine The only FDA approved use for clomipramine is for treating obsessive-compulsive disorder (OCD) in ages 10 and older. For the treatment of OCD, clomipr ... Read the Article 1 6 Activity Info
Clonazepam Clonazepam is a benzodiazepine drug used for the acute management of panic disorder, epilepsy, and non-convulsive status epilepticus. It also has many ... Read the Article 1.25 8 Activity Info
Clonidine Toxicity Clonidine is a commonly prescribed biochemical derivative of imidazoline with a variety of clinical uses. It was originally developed as a nasal decon ... Read the Article 1 4 Activity Info
Clotrimazole Clotrimazole is a medication used in the management and treatment of fungal infections. It is in the imidazole class of drugs. This activity outlines ... Read the Article 1 5 Activity Info
Clozapine Clozapine is an FDA-approved atypical antipsychotic medication for treatment-resistant schizophrenia. Clozapine is not the first-line drug of choice d ... Read the Article 1 7 Activity Info
CNS Lymphoma Primary central nervous system lymphoma (PCNSL) is an extranodal non-Hodgkin lymphoma. It is a rare entity and involves the central nervous system (CN ... Read the Article 1 4 Activity Info
Cocaine Cocaine hydrochloride topical solution contains 4% cocaine. It is not FDA-approved but allowed for only the following indications: topical anesthesia ... Read the Article 1.25 10 Activity Info
Cocaine Toxicity Cocaine abuse is a major worldwide health problem. Patients with acute cocaine toxicity may require urgent treatment for tachycardia, dysrhythmia, hyp ... Read the Article 1.25 8 Activity Info
Codeine Codeine is a medication used in the management and treatment of chronic pain. It is in the opioid class of medications. This activity outlines the ind ... Read the Article 1 6 Activity Info
Colesevelam Colesevelam is an FDA approved antihyperlipidemic drug. When treating hyperlipidemia, colesevelam should be used in conjunction with restriction of ch ... Read the Article 1 5 Activity Info
Coma Altered mental status is a catch-all term that includes a spectrum of patient behaviors ranging from confusion to deep unresponsiveness. Coma is at on ... Read the Article 1 6 Activity Info
Contrast Agent Toxicity Contrast agents, also called contrast media, are substances used to enhance the radiodensity of a targeted tissue by altering the way that electromagn ... Read the Article 1 5 Activity Info
Copper Toxicity Copper metabolism plays an important role in physiologic homeostasis. Copper toxicity, however, induces several pathologic processes that are detrimen ... Read the Article 1 4 Activity Info
Crotalidae Envenomation Crotalid envenomations cause a spectrum of disease, with both localized and systemic toxicity, which can result in both prolonged morbidity and rarely ... Read the Article 1 6 Activity Info
Cyanide Toxicity Cyanide is a rapidly acting substance that is traditionally known as a poison. Hydrogen cyanide was first isolated from Prussian blue dye in 1786 and ... Read the Article 1.25 12 Activity Info
Cyanosis Cyanosis is characterized by a blueish discoloration of the skin or mucous membranes. Cyanosis is frequently encountered in clinical practice, and the ... Read the Article 1 3 Activity Info
Cyclic Vomiting Syndrome Cyclic vomiting syndrome is characterized by recurrent episodes of nausea and vomiting lasting from hours to days in the absence of identifiable patho ... Read the Article 1 5 Activity Info
Dakin Solution Dakin solution, also called Dakin fluid or Carrel-Dakin fluid, is a dilute sodium hypochlorite (NaClO) solution that is commonly known as bleach. The ... Read the Article 1 4 Activity Info
Dantrolene Dantrolene sodium is a postsynaptic muscle relaxant with multiple indications in the fields of anesthesiology and neurology. While there are many indi ... Read the Article 1 6 Activity Info
Dapsone Dapsone is indicated for a variety of conditions, both dermatologic and non-dermatologic. The FDA-approved indications are leprosy and dermatitis herp ... Read the Article 1.25 10 Activity Info
Daunorubicin Daunorubicin is an anthracycline antibiotic mainly used to treat various types of cancers, especially leukemias. It can be used to treat both acute an ... Read the Article 1 5 Activity Info
Deadly Single Dose Agents Although the basics of evaluating and treating most unknown ingestants are well known, many overdoses require very specific treatment if the patient i ... Read the Article 1.25 8 Activity Info
Deferoxamine Deferoxamine is a medication used in Iron and aluminum toxicity. It is in the chelator class of drugs. This activity reviews the indications, mechanis ... Read the Article 1 7 Activity Info
Desflurane The FDA-approved indications for desflurane are induction or maintenance of anesthesia in adults. It may also be used for maintenance of anesthesia in ... Read the Article 1 5 Activity Info
Desmopressin Desmopressin is a drug which acts on the vasopressin receptors of the body. It has many relevant clinical uses, ranging from nocturnal enuresis to hem ... Read the Article 1 7 Activity Info
Desvenlafaxine Desvenlafaxine is an antidepressant that is an FDA-approved drug to treat major depressive disorder in adults. For healthy women who have contraindica ... Read the Article 1 6 Activity Info
Dexamethasone Dexamethasone has a wide variety of uses in the medical field. As a treatment, dexamethasone has been useful in the treatment of acute exacerbation of ... Read the Article 1 4 Activity Info
Dexrazoxane Dexrazoxane is a medication used in the management and treatment of anthracycline-induced cardiotoxicity and extravasation injuries. It is in the clas ... Read the Article 1 5 Activity Info
Dextran Dextran is a medication used in the management and treatment of various clinical conditions, including during hemorrhage, shock, surgical procedures, ... Read the Article 1 5 Activity Info
Dextromethorphan Dextromethorphan received FDA approval in 1958 for its use as a cough suppressant. It is one of the most common compounds found in the majority of the ... Read the Article 1 4 Activity Info
Dextromethorphan Toxicity Dextromethorphan is a drug used in many over-the-counter cough and cold medicines for its antitussive effects. It comes in oral strips, lozenges, liqu ... Read the Article 1 4 Activity Info
Diazepam Diazepam is a benzodiazepine medication that is FDA approved for the management of anxiety disorders, short-term relief of anxiety symptoms, spasticit ... Read the Article 1.25 9 Activity Info
Diclofenac Diclofenac is a medication used in the management and treatment of inflammatory conditions and pain. It is in the class of non-steroidal anti-inflamma ... Read the Article 1 5 Activity Info
Didanosine Didanosine is a medication used in the management and treatment of human immunodeficiency virus (HIV). It is in the nucleoside reverse transcriptase i ... Read the Article 1 6 Activity Info
Digitalis Toxicity Digoxin is a well-known cardiac glycoside and one of the oldest drugs used today in cardiovascular medicine. It has wide-ranging beneficial effects an ... Read the Article 1 6 Activity Info
Digoxin Digoxin is a medication used in the management and treatment of heart failure and certain arrhythmias and abortion. It is in the cardiac glycoside cla ... Read the Article 1.75 23 Activity Info
Digoxin Immune Fab Digoxin immune fab is a medication used in the management and treatment of digoxin toxicity. Most toxicity cases are seen in patients with a past medi ... Read the Article 1 6 Activity Info
Digoxin Toxicity Digoxin is a cardiac glycoside derived from the foxglove plant (digitalis species). It has inotropic effects and is utilized in the management of syst ... Read the Article 1.25 9 Activity Info
Dimercaprol Dimercaprol is a medication used in the treatment of toxic exposure to arsenic, mercury, gold, and lead. It is in the chelating class of drugs. This a ... Read the Article 1 6 Activity Info
Diphenhydramine Diphenhydramine, which is available as an over-the-counter medication, is a first-generation antihistamine that is used in a variety of conditions to ... Read the Article 1 6 Activity Info
Diphenhydramine Toxicity Diphenhydramine is most often used for the treatment of nausea, vomiting, allergic rhinitis, mild to severe allergic reactions (e.g., anaphylaxis), an ... Read the Article 1.25 8 Activity Info
Diphenoxylate and Atropine Diphenoxylate/atropine combination is a medication used in the management and treatment of diarrhea. It is in the antimotility class of drugs. This ac ... Read the Article 1.25 11 Activity Info
Disease Modifying Anti-Rheumatic Drugs (DMARD) Disease-modifying antirheumatic drugs (DMARDs) are a class of drugs indicated for the treatment of several inflammatory arthritides including rheumato ... Read the Article 1 5 Activity Info
Disulfiram Disulfiram is one of three drugs approved by the Federal Drug Administration (FDA) for the treatment of alcohol dependence. It is a second-line option ... Read the Article 1 6 Activity Info
Doxazosin Doxazosin is a medication used in the management and treatment of benign prostatic hyperplasia, hypertension, ureteral stones, and PTSD associated nig ... Read the Article 1 6 Activity Info
Doxepin Doxepin is a medication used in the treatment of major depressive disorder, anxiety, insomnia as well as in the management of skin pruritus. It is in ... Read the Article 1 5 Activity Info
Doxylamine Doxylamine is a medication used in the management and treatment of nausea and vomiting of pregnancy (NVP), allergic rhinitis, and insomnia. It is in t ... Read the Article 1 6 Activity Info
Dronabinol Dronabinol is synthetic tetrahydrocannabinol ('THC'), which obtained FDA approval in 1985 for the treatment of HIV/AIDs-induced anorexia and chemother ... Read the Article 1.25 8 Activity Info
Drug and Alcohol Use The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition includes 10 separate classes of drugs of abuse, which include alcohol, caffei ... Read the Article 1.25 7 Activity Info
Drug Induced Hepatotoxicity Drug-induced hepatotoxicity is an acute or chronic liver injury secondary to drugs or herbal compounds. It is difficult to diagnose because the presen ... Read the Article 1 6 Activity Info
Drug Induced Valvular Heart Disease Drug-induced valvular heart disease (DIVHD) is a condition involving changes in the morphology and functionality of valvular leaflets secondary to exp ... Read the Article 1 5 Activity Info
Drug Interactions In Palliative Care Drug-drug interactions (DDI) are a significant cause of adverse drug events (ADE) in palliative care. This activity will highlight the mechanism of ac ... Read the Article 1.25 13 Activity Info
Drug-Induced Lupus Erythematosus Drug-induced lupus erythematosus (DIL) is an autoimmune phenomenon where the patient develops symptoms similar to systemic lupus erythematosus (SLE) a ... Read the Article 1 5 Activity Info
Edoxaban Edoxaban is a medication used in the management and treatment of pulmonary embolism (PE), deep venous thrombosis (DVT), and non-valvular atrial fibril ... Read the Article 1 5 Activity Info
Electronic Vaping Delivery Of Cannabis And Nicotine This activity outlines the current scientific literature and knowledge of the risks and benefits of inhaling nicotine through proprietary devices. It ... Read the Article 1 5 Activity Info
Emicizumab Emicizumab is a medication used in the management and treatment of hemophilia A. It belongs to the bispecific monoclonal antibody class of medications ... Read the Article 1.25 9 Activity Info
Enalapril Enalapril is a medication used in the management of hypertension and congestive heart failure. It is an angiotensin-converting enzyme inhibitor. This ... Read the Article 1.25 10 Activity Info
Enalaprilat Enalaprilat injection is used in the management of hypertension when oral therapy is not practical. Enalaprilat is the active metabolite of the oral p ... Read the Article 1 5 Activity Info
Epidural Morphine Epidural morphine is a medication used for analgesia, as an adjunct to general anesthesia, or as a sole technique for surgical anesthesia. Morphine wa ... Read the Article 1 5 Activity Info
Epinephrine Epinephrine is one of the most commonly used agents in a variety of settings as it functions as medication and hormone. It is currently FDA-approved f ... Read the Article 1.5 17 Activity Info
Ergotamine/Caffeine The combination of ergotamine and caffeine is a medication used in the management and treatment of acute migraines. It is in the ergot alkaloid class ... Read the Article 1.25 9 Activity Info
Escitalopram Escitalopram is a medication used in the management and treatment of major depressive disorder and generalized anxiety disorder. It is in the selectiv ... Read the Article 1 7 Activity Info
Estrogen Therapy Estrogen therapy is a form of hormone replacement therapy that is often used in the management and treatment of menopausal symptoms, especially vasomo ... Read the Article 1.25 10 Activity Info
Ethambutol Ethambutol is a medication used in the management and treatment of tuberculosis. It is a bacteriostatic drug that inhibits cell wall synthesis. This a ... Read the Article 1.25 8 Activity Info
Ethanol Ethanol is an alcohol by chemical composition, used in the management and treatment of methanol/ethylene glycol toxicity. Ethanol has also been used e ... Read the Article 1 4 Activity Info
Ethanol Toxicity Ethanol toxicity results from the ingestion of large amounts of ethanol, usually in the form of alcohol. It affects multiple organ systems in both the ... Read the Article 1 4 Activity Info
Ethylene Glycol Toxicity Ethylene glycol (C2H6O2) is a toxic alcohol that is found in various household and industrial agents. Ethylene glycol exposure can be extremely danger ... Read the Article 1.25 7 Activity Info
Ethylenediaminetetraacetic Acid (EDTA) Ethylenediaminetetraacetic acid (EDTA) is a medication used in the management and treatment of heavy metal toxicity. It is in the chelating class of d ... Read the Article 1 4 Activity Info
Evaluation and Treatment of Snake Envenomations Snakebites are responsible for a significant degree of morbidity and mortality worldwide, especially in low resource countries. There are over 600 spe ... Read the Article 1 4 Activity Info
Exenatide Exenatide is FDA-indicated to improve glycemic control in adult patients with type 2 diabetes mellitus when used as an adjunct to diet and exercise. I ... Read the Article 1 5 Activity Info
Facial Burns Burn injuries are a significant health issue and are a leading cause of accidental death or injury in the U.S. Burns to the face can affect many speci ... Read the Article 1.75 14 Activity Info
Factitious Hypoglycemia Factitious hypoglycemia is the intentional attempt to induce low blood glucose levels and remains one of the diagnostic challenges that face endocrino ... Read the Article 1 4 Activity Info
Famotidine Famotidine decreases the production of stomach acid, and its pharmacologic activity is used in the treatment of acid-related gastrointestinal conditio ... Read the Article 1 6 Activity Info
Fatty Liver Non-alcoholic Fatty Liver Disease (NAFLD) or "Fatty Liver" corresponds to the presence of macrovesicular changes without inflammation (steatosis) and ... Read the Article 1 6 Activity Info
Fentanyl Fentanyl is a potent synthetic opioid, which, similar to morphine, produces analgesia but to a greater extent. This robust pharmacologic agent is typi ... Read the Article 1 7 Activity Info
Fentanyl Transdermal Transdermal Fentanyl is a medication used in the management and treatment of chronic pain and cancer pain. It is part of the opioid class of drugs. Th ... Read the Article 1.25 10 Activity Info
Filgrastim Filgrastim is a medication used for the management and treatment of neutropenia in patients with myelosuppression from chemotherapy or radiation, whic ... Read the Article 1 5 Activity Info
Fire Ant Bites Fire ants tend to be an aggressive insect that will sting causing very painful reactions. There are two types of fire ants which belong to the Soleno ... Read the Article 1 5 Activity Info
Flucytosine Flucytosine is a medication used in the management and treatment of systemic and severe candida and cryptococcus infections. It is in the antimetaboli ... Read the Article 1 5 Activity Info
Fludrocortisone Fludrocortisone is a synthetic adrenal steroid with high mineralocorticoid activity that is a commonly used drug for adrenocortical insufficiency. Thi ... Read the Article 1 4 Activity Info
Flumazenil Flumazenil is a benzodiazepine antagonist. The primary FDA-approved clinical uses for flumazenil include reversal agent for benzodiazepine overdose an ... Read the Article 1 6 Activity Info
Fluorides and Fluorocarbons Toxicity Fluorocarbons are fluorinated carbon chain polymers that are used in an assortment of household and commercial products as waterproofing agents, lubri ... Read the Article 1 5 Activity Info
Fluorouracil 5-Fluorouracil (5-FU) is a medication used for the treatment of various neoplasms. It is in the chemotherapy class of medications. This activity outli ... Read the Article 1 7 Activity Info
Fluoxetine Fluoxetine is FDA-approved for major depressive disorder (age eight and older), obsessive-compulsive disorder, panic disorder, bulimia, binge eating d ... Read the Article 1 6 Activity Info
Fluvastatin In adults, fluvastatin is indicated for hypercholesterolemia and mixed dyslipidemia to decrease the amount of total cholesterol in the blood. Specific ... Read the Article 1 5 Activity Info
Fosinopril Fosinopril is classified as an angiotensin-converting enzyme inhibitor and has been available for nearly three decades. Fosinopril has some key featur ... Read the Article 1 5 Activity Info
Fresh Frozen Plasma (FFP) Fresh frozen plasma is indicated for the deficiency of coagulation factors with abnormal coagulation tests in the presence of active bleeding. Fresh f ... Read the Article 1 6 Activity Info
Fulvestrant Fulvestrant is used in the management and treatment of advanced breast cancer. It is a selective estrogen receptor degrader. This activity outlines th ... Read the Article 1 5 Activity Info
GABA Receptor Positive Allosteric Modulators GABA positive allosteric modulators are medications used in the management and treatment of seizures, sedation, anxiolytic, alcohol withdrawal, and mu ... Read the Article 1 5 Activity Info
Gabapentin Gabapentin is an anticonvulsive medication that originally saw use as a muscle relaxer and anti-spasmodic medication, but later it was discovered it h ... Read the Article 1.25 8 Activity Info
Gamma-Hydroxybutyrate Toxicity Gamma hydroxybutyrate (GHB) is pharmaceutically manufactured as sodium oxybate for the treatment of narcolepsy. This formulation is considered a Sched ... Read the Article 1 4 Activity Info
Gemfibrozil Gemfibrozil is an FDA approved fibric acid agent (fibrate) for the management of hypertriglyceridemia (particularly in type IV and V hyperlipidemia). ... Read the Article 1 5 Activity Info
Gentamicin Gentamicin is an aminoglycoside antibiotic used in the treatment of several gram-negative infections. This activity aims to review the indications, ac ... Read the Article 1 7 Activity Info
Ginger Root Ginger root is a plant-based, whole food spice used in the personal or professional treatment of various conditions, ranging from gastrointestinal ups ... Read the Article 1 5 Activity Info
Glipizide Glipizide is a second-generation sulfonylurea that is FDA-approved for the treatment of adults with diabetes mellitus type 2. It is administered as an ... Read the Article 1 7 Activity Info
Glucosamine Sulfate Glucosamine sulfate is an oral supplement used in the management and treatment of osteoarthritis. This activity outlines the indications, hypothesized ... Read the Article 1 4 Activity Info
Granulomatosis with Polyangiitis Granulomatosis with polyangiitis (GPA) is a rare vasculitis affecting small vessels. Hallmark features include necrotizing granulomas and pauci-immune ... Read the Article 1.25 11 Activity Info
Gray Baby Syndrome Gray baby syndrome is an adverse reaction to chloramphenicol that is characterized by abdominal distention, hemodynamic collapse, and ashen-gray skin ... Read the Article 1 5 Activity Info
Halothane Toxicity Halothane is a medication previously used for induction and maintenance of general anesthesia. After its large impact on medicine and anesthesia speci ... Read the Article 1 6 Activity Info
Heavy Metal Toxicity Heavy metals are elements found in nature that accumulate in the environment mostly due to anthropogenic activities. Humans are exposed to them by occ ... Read the Article 1 5 Activity Info
Hemodialysis Dialysis is a form of renal replacement therapy. The kidney’s role of filtration of the blood is supplemented by artificial equipment for the removal ... Read the Article 1.25 6 Activity Info
Heparin Induced Thrombocytopenia Heparin-induced thrombocytopenia (HIT) is a severe complication that can occur in patients exposed to any form or amount of heparin products. A fall i ... Read the Article 1.5 16 Activity Info
Hepatic Cirrhosis Cirrhosis is characterized by fibrosis and nodule formation of the liver secondary to chronic injury, leading to alteration of the normal lobular orga ... Read the Article 1.5 18 Activity Info
Hepatic Failure Acute liver failure (ALF) is a complex clinical syndrome characterized by coagulopathy, elevated liver biochemistry, and hepatic encephalopathy withou ... Read the Article 1 4 Activity Info
Heroin Heroin, also known as diacetylmorphine, is derived from the opium poppy plant. Professionals initially touted morphine as a substitute with less misus ... Read the Article 1 5 Activity Info
Heroin Toxicity Heroin, also known as diacetylmorphine, is a very efficient prodrug and more potent than Morphine. Many deaths are caused by heroin overdoses througho ... Read the Article 1 3 Activity Info
Histamine Toxicity Scombroid poisoning results from eating fish that have been improperly stored. The primary toxic agent implicated in scombroid toxicity is histidine, ... Read the Article 1 8 Activity Info
Hydralazine Hydralazine is used orally as a therapeutic agent to treat essential hypertension and intravenously to lower blood pressure urgently or emergently. FD ... Read the Article 1.25 9 Activity Info
Hydrocarbon Toxicity Hydrocarbons are compounds containing hydrogen and carbon. These are typically the chief components in many types of fuels. They can come in the form ... Read the Article 1 4 Activity Info
Hydrocodone Hydrocodone is a schedule II semi-synthetic opioid medication used to treat pain. Hydrocodone is also an antitussive indicated for cough in adults. In ... Read the Article 1 5 Activity Info
Hydrocodone and Acetaminophen Hydrocodone is one of the most common pain medications prescribed by clinicians and one of the most abused by the patients. It is a relatively potent ... Read the Article 1 5 Activity Info
Hydrofluoric Acid Burns Hydrofluoric (HF) acid is an extremely powerful inorganic acid and a vigorous dehydrating agent that is used in many industrial branches. Domestic con ... Read the Article 1 4 Activity Info
Hydrogen Sulfide Toxicity Hydrogen sulfide can be found in many environments, and toxicity can arise from both direct contact and as the chemical enters the bloodstream. At hig ... Read the Article 1 5 Activity Info
Hydromorphone Hydromorphone is a medication used in the management and treatment of moderate to severe acute pain as well as severe chronic pain. It is in the opioi ... Read the Article 1 6 Activity Info
Hydroquinone Hydroquinone cream is the standard depigmentation or skin lightening agent. Clinically it is used to treat areas of dyschromia, such as in, melasma, c ... Read the Article 1 5 Activity Info
Hydroxocobalamin Hydroxocobalamin is a medication used in the management and treatment of vitamin B12 deficiency and acute cyanide toxicity. It is in the anti-anemic c ... Read the Article 1 4 Activity Info
Hymenoptera Stings The Hymenoptera order includes over 150,000 different species of flying and non-flying insects. Some species within this order have modified oviposito ... Read the Article 1 6 Activity Info
Hyperthyroidism The thyroid gland is a bilobed structure located in the anterior aspect of the trachea between the cricoid cartilage and the suprasternal notch. Each ... Read the Article 1.75 23 Activity Info
Hypokalemia One of the most common electrolyte disturbances seen in clinical practice is hypokalemia. Hypokalemia is more prevalent than hyperkalemia, and most ca ... Read the Article 1.25 11 Activity Info
Hypothyroidism Hypothyroidism results from low levels of thyroid hormone with varied etiology and manifestations. The drug of choice for the treatment of hypothyroid ... Read the Article 1.75 20 Activity Info
Ibuprofen Toxicity Ibuprofen, 2-(4-isobutylphenyl)propionic acid, belongs to the class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs) and was discovered b ... Read the Article 1 6 Activity Info
Idiopathic Pulmonary Hemosiderosis Idiopathic pulmonary hemosiderosis (IPH) is a rare disease characterized by repeated episodes of a diffuse alveolar hemorrhage resulting in the accumu ... Read the Article 1 5 Activity Info
Idioventricular Rhythm Idioventricular rhythm is a slow regular ventricular rhythm with a rate of less than 50 bpm, absence of P waves, and a prolonged QRS interval. When th ... Read the Article 1 4 Activity Info
Ifosfamide Ifosfamide is a cytotoxic medication used in the management and treatment of various cancers such as lymphomas, sarcomas, and lung cancers. It is in t ... Read the Article 1 5 Activity Info
Imipramine Imipramine is a medication used in the treatment of depression and anxiety. It is a tertiary amine tricyclic antidepressant. This activity reviews the ... Read the Article 1 6 Activity Info
Indinavir Indinavir is an alpha-amino acid amide protease inhibitor used as a treatment therapy for Human immunodeficiency virus (HIV) infections, which can lea ... Read the Article 1.25 8 Activity Info
Inhalational Anesthetic Inhalation anesthetics (nitrous oxide, halothane, isoflurane, desflurane, sevoflurane most commonly used agents in practice today) are used for induct ... Read the Article 1 7 Activity Info
Inhaled Corticosteroids Inhaled corticosteroids (ICS) are the FDA-indicated treatment of choice in preventing asthma exacerbation in patients with persistent asthma. Persiste ... Read the Article 1 4 Activity Info
Insect Bites The term "bug bite" is commonly used to denote both bites and stings inflicted by members of the phylum Arthropoda. Arthropods make up the largest di ... Read the Article 1.25 5 Activity Info
Insulin Insulin is a medication used in the treatment and management of diabetes mellitus type-1 and sometimes diabetes mellitus type-2, both of which are a s ... Read the Article 1.25 12 Activity Info
Intracerebral Hemorrhage This activity aims to outline the pathophysiology, risk factors, presentation diagnosis, and complications of intracerebral hemorrhages. This activity ... Read the Article 1.25 7 Activity Info
Intrathecal Morphine Morphine is an opioid administered for acute and chronic pain conditions. The advantage of intrathecal (IT) morphine over intravenous (IV), oral (PO), ... Read the Article 1 6 Activity Info
Iodine Toxicity Although the consequences of iodine deficiency have been recognized for years, there has not been much emphasis on the prevalence or the consequences ... Read the Article 1 5 Activity Info
Iontophoresis Analgesic Medications Analgesic iontophoresis is the administration of analgesic medications via iontophoresis used in the management and treatment of pain. The technique m ... Read the Article 1 5 Activity Info
Iron Iron is a mineral essential to the human body. It is administered for the treatment of iron deficiency. It is available in many formulations that belo ... Read the Article 1 5 Activity Info
Iron Dextran Iron dextran is an injectable medication used in the management of iron deficiency anemia, particularly in patients who are unable to tolerate iron by ... Read the Article 1 6 Activity Info
Iron Supplementation Iron is a medication used in the management and treatment of iron deficiency anemia. This activity illustrates the indications, action, and contraind ... Read the Article 1.25 8 Activity Info
Iron Toxicity Iron poisoning is one of the most common toxic ingestion and one of the most deadly among children. Failure to diagnose and treat iron poisoning can h ... Read the Article 1 6 Activity Info
Isoniazid Toxicity Isoniazid (INH) is a potent bactericidal antibiotic used in the treatment of tuberculosis. Treatment with INH therapy has a risk of toxicity, which ca ... Read the Article 1.25 8 Activity Info
Isopropanol Toxicity Isopropanol, or isopropyl alcohol, is a clear, colorless liquid that emits an odor that resembles acetone. It is a commercially available product main ... Read the Article 1 5 Activity Info
Ketamine In Acute and Chronic Pain Management Acute and chronic pain remain important health problems both in the United States and worldwide. With the rise in the prevalence of many chronic degen ... Read the Article 1 5 Activity Info
Ketamine Toxicity Ketamine is a structural analog of the dissociative anesthetic and recreational drug phencyclidine (PCP). Similar to phencyclidine, ketamine causes an ... Read the Article 1 6 Activity Info
Lamotrigine Lamotrigine can be used to treat the following partial seizures, primary generalized tonic-clonic seizures, bipolar I disorder maintenance and Lennox- ... Read the Article 1 6 Activity Info
Lead Toxicity Lead became a common occupational toxin with the birth of the Industrial Revolution, by the end of the 19-century childhood lead poisoning secondary t ... Read the Article 1.5 14 Activity Info
Leflunomide Leflunomide is a medication used in the management and treatment of rheumatoid arthritis. It is in the nonbiological DMARDs class of medications. This ... Read the Article 1 5 Activity Info
Leucovorin Leucovorin is a medication used in the treatment of methotrexate toxicity and chemotherapy regimens. Leucovorin is a folate analog. This activity revi ... Read the Article 1 6 Activity Info
Levodopa (L-Dopa) Levodopa is the precursor to dopamine. Most commonly, clinicians use levodopa as a dopamine replacement agent for the treatment of Parkinson's disease ... Read the Article 1 7 Activity Info
Levonorgestrel Levonorgestrel, also known as the morning-after pill, is a first-line oral emergency contraceptive pill that has approval from the World Health Organi ... Read the Article 1 6 Activity Info
Levothyroxine Oral levothyroxine is primarily indicated for the treatment of primary, secondary, and tertiary hypothyroidism. Primary hypothyroidism is when the pro ... Read the Article 1 5 Activity Info
Lidocaine Lidocaine is a local anesthetic agent that is commonly used for local and topic anesthesia, but which also has antiarrhythmic and analgesic uses and c ... Read the Article 1.25 12 Activity Info
Lidocaine Toxicity Lidocaine is a local anesthetic drug that produces transient loss of sensory, motor, and autonomic function when the drug is injected or applied in pr ... Read the Article 1 6 Activity Info
Lipid Emulsion Therapy Lipid emulsion therapy is a medication used in the management and treatment of Local anesthetic toxicity. This activity reviews the indications, actio ... Read the Article 1 6 Activity Info
Lipid Lowering Drug Therapy Patients at an increased risk of having a cardiovascular event (cardiovascular death, nonfatal MI, nonfatal stroke, coronary revascularization, or uns ... Read the Article 1 4 Activity Info
Lisinopril Lisinopril is classified as an angiotensin-converting enzyme inhibitor and has been available for nearly three decades. Lisinopril has some key featur ... Read the Article 1 6 Activity Info
Lithium Toxicity The drug of choice for recurrent bipolar illness management remains to be lithium. Lithium, a monovalent cation similar to sodium with an unknown mech ... Read the Article 1.25 8 Activity Info
Liver Toxicity One of the most important causes of liver dysfunction is drug-induced liver injury (DILI) which can lead to a wide spectrum of symptoms ranging from m ... Read the Article 1.25 8 Activity Info
Local Anesthetic Toxicity Local anesthetics are commonly used in most medical and dental practice. While adverse effects are rare, the rising prevalence of local anesthetics in ... Read the Article 1 5 Activity Info
Loop Diuretics Loop diuretics are medications used in the management and treatment of fluid overload conditions such as heart failure, nephrotic syndrome or cirrhosi ... Read the Article 1.25 11 Activity Info
Loperamide Loperamide is a medication used in the treatment of diarrhea. It classifies as an anti-diarrheal agent. The use of loperamide in high doses has been a ... Read the Article 1 7 Activity Info
Lorazepam Lorazepam is a benzodiazepine medication commonly used as the sedative and anxiolytic of choice in the inpatient setting owing to its fast (1 to 3 min ... Read the Article 1 5 Activity Info
Losartan Losartan is FDA approved for the treatment of several medical conditions, which include the following: hypertension, diabetic nephropathy. ARBs are kn ... Read the Article 1 8 Activity Info
Lovastatin Lovastatin is a lipid-lowering medication part of the statin drug class used in the treatment and prevention of coronary heart disease, hypercholester ... Read the Article 1 5 Activity Info
Lysergic Acid Diethylamide (LSD) Lysergic acid diethylamide (LSD) is a classical hallucinogen. No approved indications for LSD-assisted therapy exist today. It has been used in the pa ... Read the Article 1 5 Activity Info
Magnesium Sulfate Magnesium sulfate is a medication used in the management and treatment of multiple clinical conditions and holds several on and off label uses. This ... Read the Article 1 5 Activity Info
Magnesium Toxicity Magnesium toxicity is commonly caused by the overuse of magnesium-containing medication or under-excretion of magnesium by the kidneys. Early recognit ... Read the Article 1 5 Activity Info
Manganese Toxicity Manganese (Mn) toxicity is a well-established result of repeated occupational and nutritional exposures. Though this syndrome is relatively uncommon, ... Read the Article 1.25 5 Activity Info
Marijuana Cannabis, also known as marijuana, is commonly sought out by patients for various conditions. Conversely, many providers are uncomfortable prescribing ... Read the Article 1.25 9 Activity Info
Marijuana Toxicity The term "marijuana" typically refers to the tobacco-like preparations of the leaves and flowers of the plant cannabis sativa. The active ingredient i ... Read the Article 1 4 Activity Info
Meclizine Meclizine is a medication used in the management and treatment of nausea, vomiting, and dizziness caused by motion sickness and vertigo. Meclizine bel ... Read the Article 1 5 Activity Info
Mercaptopurine Mercaptopurine is a medication used in the management and treatment of acute lymphoblastic leukemia. It is in the class of medications known as purine ... Read the Article 1 6 Activity Info
Mercury Toxicity Mercury has been used for centuries in multiple capacities including medicinal and widespread industrial use. Because of this, it is a common chemical ... Read the Article 1 7 Activity Info
Mesna Mesna is a medication used in the management and treatment of hemorrhagic cystitis associated with chemotherapy. This activity outlines the indication ... Read the Article 1 6 Activity Info
Metabolic Acidosis Acid-base disorders are disturbances in the homeostasis of hydrogen ion concentration in the plasma. Any process that increases the serum hydrogen ion ... Read the Article 1.5 15 Activity Info
Methadone Methadone is a medication used in the management and treatment of opioid use disorder and as an analgesic in chronic pain. It is a synthetic long-term ... Read the Article 1 5 Activity Info
Methamphetamine Methamphetamine is one of the powerful stimulants of the central nervous system (CNS). It is sometimes a second-line treatment for attention deficit h ... Read the Article 1 4 Activity Info
Methamphetamine Toxicity Methamphetamine is a highly addictive psychostimulant drug that is a derivative of amphetamine. Methamphetamine can produce euphoria and stimulant eff ... Read the Article 1 4 Activity Info
Methanol Toxicity Methanol (CH3OH) is a toxic alcohol that is found in various household and industrial agents. Methanol exposure can be extremely dangerous, with signi ... Read the Article 1.75 23 Activity Info
Methemoglobinemia Methemoglobinemia is a condition with life-threatening potential in which diminution of the oxygen-carrying capacity of circulating hemoglobin occurs ... Read the Article 1 5 Activity Info
Methocarbamol Methocarbamol is a medication used in the management and treatment of acute musculoskeletal pain. It is in the skeletal muscle relaxant class of medic ... Read the Article 1 5 Activity Info
Methylene Blue Methylene blue is a medication used in the management and treatment of methemoglobinemia, a condition in which hemoglobin decreases its ability to car ... Read the Article 1 5 Activity Info
Methylxanthines Methylxanthines are drugs primarily employed in the treatment of non-obstructive lung pathology. This activity will highlight the indications, mechani ... Read the Article 1 5 Activity Info
Metolazone Metolazone is a cardiovascular agent, specifically a quinazoline diuretic related to the thiazide class. It is available in a generic formulation in t ... Read the Article 1 6 Activity Info
Metoprolol Metoprolol is FDA-approved for the treatment of angina, heart failure, myocardial infarction, atrial fibrillation/flutter, and hypertension. Off-label ... Read the Article 1 5 Activity Info
Milk Thistle Herbal products have become increasingly popular, especially among those with chronic disease. Milk thistle has been used for hundreds of years by her ... Read the Article 1 5 Activity Info
Monoamine Oxidase Inhibitor Toxicity Monoamine oxidase inhibitors (MAOIs) are a class of antidepressants. The use of MAOIs has declined in the past few decades due to the introduction of ... Read the Article 1 4 Activity Info
Monoamine Oxidase Inhibitors (MAOI) Monoamine oxidase inhibitors (MAOIs) are a separate class from other antidepressants, treating different forms of depression as well as other nervous ... Read the Article 1 6 Activity Info
Morphine FDA-approved usage of morphine sulfate includes moderate to severe pain that may be acute or chronic. Most commonly used in pain management, morphine ... Read the Article 1.25 13 Activity Info
Muscarinic Agonists Muscarinic agonists are parasympathomimetic drugs and are indicated for ileus, urinary retention, glaucoma, Alzheimer disease, and other symptoms. Thi ... Read the Article 1 6 Activity Info
Muscarinic Antagonists The muscarinic antagonist is a class medication used in the management and treatment of numerous different conditions, including COPD and organophosph ... Read the Article 1 5 Activity Info
N Acetylcysteine N-acetylcysteine (NAC) is the mainstay of therapy for acetaminophen toxicity. NAC has FDA approval for the treatment of potentially hepatotoxic doses ... Read the Article 1 6 Activity Info
Nalbuphine Nalbuphine is FDA indicated for moderate to severe pain in which an opioid agent is required when other alternative treatments have been insufficient. ... Read the Article 1 7 Activity Info
Naloxone Over the past two decades, the rate of overdose from opiates has increased significantly. Opiate misuse is associated with enormous morbidity and mort ... Read the Article 1.25 7 Activity Info
Naltrexone Naltrexone is an opioid antagonist used to treat alcohol use disorder and opioid dependence. It is FDA-approved for alcohol misuse and opioid dependen ... Read the Article 1 7 Activity Info
Naproxen Naproxen is FDA-approved for the treatment of acute gout, ankylosing spondylitis, bursitis, polyarticular juvenile idiopathic arthritis, osteoarthriti ... Read the Article 1 5 Activity Info
Narcotic Bowel Syndrome It is estimated that anywhere from 25% to 45% of the adult population suffers from long-term pain, which results in a poor quality of life, loss of pr ... Read the Article 1 6 Activity Info
Natalizumab Natalizumab is an FDA-approved, monoclonal antibody approved for the treatment of multiple sclerosis and Crohn's disease. The drug was originally appr ... Read the Article 1.25 11 Activity Info
Nebivolol Nebivolol is a medication used in the management and treatment of hypertension. It is in the beta-blocker class of drugs. This activity describes the ... Read the Article 1 6 Activity Info
Nephrotic Syndrome Nephrotic syndrome (NS) is a clinical syndrome defined by massive proteinuria (greater than 40 mg/m2 per hour) responsible for hypoalbuminemia (less t ... Read the Article 1.25 9 Activity Info
Nerve Agents Nerve agents represent a significant contributor to morbidity and mortality in toxicology and emergency medicine. Patients affected by nerve agents pr ... Read the Article 1.25 9 Activity Info
Neuroleptic Agent Toxicity The use of these neuroleptic agents has become more widespread. Knowledge of the toxicity and adverse effects associated with their use is becoming pa ... Read the Article 1 5 Activity Info
Neuromuscular Blocking Agents The widespread use of neuromuscular blocking agents (NMBA) was a significant milestone in the development of anesthesia. Before the introduction of N ... Read the Article 1 5 Activity Info
Niacin Toxicity Niacin is a medication used in the management and treatment of hyperlipidemia. It is in the vitamin supplement class of drugs. This activity reviews ... Read the Article 1 5 Activity Info
Nicotine Nicotine replacement therapy (NRT) is for those who want to quit smoking, as abruptly quitting can cause withdrawals and cravings. Nicotine withdrawal ... Read the Article 1 5 Activity Info
Nitroglycerin Nitroglycerin is a vasodilatory drug used primarily to provide relief from anginal chest pain. It is currently FDA approved for the acute relief of a ... Read the Article 1 7 Activity Info
Nitrous Oxide Nitrous oxide is an odorless, colorless, non-flammable gas. While nitrous oxide is not flammable, it will support combustion to the same extent as ox ... Read the Article 1.25 10 Activity Info
Non-Hodgkin Lymphoma Non-Hodgkin lymphoma is a group of malignant neoplasms originating from the lymphoid tissues, mainly the lymph nodes. These tumors may result due to c ... Read the Article 1.5 12 Activity Info
Nonsteroidal Anti-Inflammatory Drugs Toxicity As a class, nonsteroidal anti-inflammatory drugs, commonly abbreviated as NSAIDs, are chemically varied, yet share similar therapeutic and adverse eff ... Read the Article 1 4 Activity Info
Norepinephrine Untreated hypotension can be a significant cause of morbidity and mortality. Norepinephrine is a first-line agent for hypotension that does not respon ... Read the Article 1 4 Activity Info
Ofloxacin Ofloxacin is a medication in the fluoroquinolone class used in the treatment of multiple gram-positive and gram-negative bacterial infections. This ac ... Read the Article 1 5 Activity Info
Olmesartan Olmesartan is a medication used in the management of hypertension. It is in the angiotensin receptor blocking (ARB) class of drugs. This activity revi ... Read the Article 1 5 Activity Info
Ondansetron Ondansetron is one of the medications most commonly used for empiric treatment. Ondansetron has extreme utility as an antiemetic drug, and it is effec ... Read the Article 1 7 Activity Info
Opioid Opioids are medications used in the management and treatment of pain, cough, or diarrhea. This activity outlines the indications, actions, and contrai ... Read the Article 1.25 12 Activity Info
Opioid Addiction Opioid use disorder and opioid addiction remain at epidemic levels in the US and worldwide. Three million US citizens and 16 million individuals world ... Read the Article 1.25 8 Activity Info
Opioid Analgesics Opioids are a class of medication used in the management and treatment of pain. This activity outlines the indications, action, and contraindications ... Read the Article 1.25 13 Activity Info
Opioid Antagonists Opioid receptor antagonists block one or more of the opioid receptors in the central or peripheral nervous system. Opioid receptors are specific trans ... Read the Article 1.25 8 Activity Info
Opioid Overdose One very common reason why patients seek medical care is for pain. Today, there are many ways to relieve pain, and one of them is with the use of opia ... Read the Article 1.25 4 Activity Info
Opioid Toxicity Opioids and opiates together comprise a class of medications widely used primarily to control severe pain. If first-line agents are not effective in c ... Read the Article 1.5 14 Activity Info
Opioid Use Disorder Opioid use disorder has a significant impact on the quality of life. It is an epidemic in the United States. The persistent use of opioids should be d ... Read the Article 1.25 9 Activity Info
Opioid Withdrawal Opioid withdrawal syndrome is a life-threatening condition resulting from opioid dependence. Opioids are a group of drugs used to manage severe pain a ... Read the Article 1 4 Activity Info
Opioid-induced Endocrinopathy Hormone replacement therapy is a mainstay of treatment for those suffering from opioid-induced endocrinopathy (OIE), which can have a significant impa ... Read the Article 1 7 Activity Info
Organophosphate Toxicity Most patients exposed to organophosphates come into contact with insecticides. The first organophosphate insecticide was created in the mid-1800s but ... Read the Article 1.25 11 Activity Info
Oxazepam Oxazepam is a short-acting benzodiazepine used for the treatment of alcohol withdrawal, management of anxiety disorders, and tension. This activity w ... Read the Article 1 5 Activity Info
Oxycodone Oxycodone is a potent opioid which can be useful when used judiciously for pain. However, it can cause physical dependence and addiction. The immediat ... Read the Article 1 6 Activity Info
Pain Management Medications Analgesics are medications used in the management and treatment of pain. They include several classes of medications (acetaminophen, nonsteroidal anti ... Read the Article 1.25 8 Activity Info
Parasympathomimetic Medications Parasympathomimetics are a class of medications that activate the parasympathetic nervous system by mimicking or modifying the effects of acetylcholin ... Read the Article 1 5 Activity Info
Pediculosis Corporis Pediculosis corporis is a skin condition caused by body lice (Pediculus humanus corporis) that feed on human blood. These lice lay their eggs in the s ... Read the Article 1 4 Activity Info
Penicillin Penicillin is a medication used in the management and treatment of a wide range of infections. It is in the beta-lactam antibiotic class of drugs. Thi ... Read the Article 1 5 Activity Info
Pentobarbital Pentobarbital is a medication used in the management and treatment of several medical conditions including seizures, intracranial pressure control, in ... Read the Article 1 6 Activity Info
Perinatal Drug Abuse And Neonatal Drug Withdrawal Drug abuse and addiction have significantly increased over the last few decades; specifically, opioid abuse and dependence have increased to epidemic ... Read the Article 1 4 Activity Info
Pharmacologic Therapy For Obesity Obesity is a metabolic disease represented by excessive adipose tissue. Its classification is based on the body mass index (BMI), which is a relations ... Read the Article 1.25 9 Activity Info
Phencyclidine Toxicity Phencyclidine (PCP) is a dissociative anesthetic that is a commonly used recreational drug. PCP is a crystalline powder that can be ingested orally, i ... Read the Article 1.25 10 Activity Info
Phenobarbital Phenobarbital is included in a class of drugs called barbiturates. This drug can be used for anti-seizure management, treatment for status epilepticus ... Read the Article 1.25 12 Activity Info
Phenol Toxicity Phenol is a historical disinfectant with continued use in industry, laboratories, and some health care settings. Phenol is a protoplasmic poison that ... Read the Article 1 5 Activity Info
Phenytoin Toxicity Phenytoin has become one of the most well-studied anticonvulsants. With an average monthly cost of $30, it has also become one of the most widely used ... Read the Article 1 4 Activity Info
Physostigmine Physostigmine is a medication most commonly used in the management and treatment of antimuscarinic toxicity as well as glaucoma. This article will hig ... Read the Article 1 6 Activity Info
Polypharmacy The term polypharmacy refers to the use of 5 or more medications, based on a review of current data. Aging places individuals at risk of multi-morbidi ... Read the Article 1 7 Activity Info
Potassium Iodide Potassium Iodide (KI) has effects in the production of thyroid hormone and is useful in treating conditions related to thyroid hormone, especially sev ... Read the Article 1 6 Activity Info
Pralidoxime Pralidoxime is a medication used in the management and treatment of organophosphate poisoning. It is in the oxime class of drugs. This activity outlin ... Read the Article 1 5 Activity Info
Pravastatin Pravastatin is a medication used in the management and treatment of primary hypercholesterolemia, hyperlipidemia, and mixed dyslipidemia. It falls und ... Read the Article 1 5 Activity Info
Prazosin Prazosin is a medication used in the management and treatment of hypertension, benign prostatic hyperplasia, PTSD associated nightmares, and Raynaud p ... Read the Article 1 5 Activity Info
Pregabalin Pregabalin is approved by the United States Food and Drug Administration (FDA) for the treatment of neuropathic pain associated with diabetic peripher ... Read the Article 1 4 Activity Info
Prescription of Controlled Substances: Benefits and Risks One of the single most difficult challenges for any prescriber is to distinguish between the legitimate prescription of controlled substances versus t ... Read the Article 1.25 5 Activity Info
Procainamide Procainamide is a medication used in the management and treatment of ventricular arrhythmias, supraventricular arrhythmias, atrial flutter/fibrillatio ... Read the Article 1 6 Activity Info
Procaine Procaine is a medication used for analgesia before a procedural intervention. It is in the local anesthetics class of drugs. This activity reviews the ... Read the Article 1 5 Activity Info
Promethazine Promethazine is a medication used in the management and treatment of allergic conditions, nausea and vomiting, motion sickness, and sedation. It also ... Read the Article 1 8 Activity Info
Propofol Toxicity Propofol is a phenol derivative administered intravenously that is commonly used for sedation and in general anesthesia. The most common formulation ... Read the Article 1 5 Activity Info
Propranolol Propranolol can be used to ameliorate the sympathetic response in angina, tachyarrhythmias, prevention of acute ischemic attacks, migraine prophylaxis ... Read the Article 1.25 10 Activity Info
Prothrombin Complex Concentrate Prothrombin complex concentrate (PCC) comes from the process of ion-exchange chromatography from the cryoprecipitate supernatant of large plasma pools ... Read the Article 1.25 9 Activity Info
Protriptyline Protriptyline hydrochloride is a tricyclic antidepressant used to improve mood in people with depression. It is also useful in treating anxiety. It is ... Read the Article 1 6 Activity Info
Pseudotumor Cerebri Pseudotumor cerebri (PTC), also known by the name idiopathic intracranial hypertension (IIH), is a disorder with increased intracranial pressure (ICP) ... Read the Article 1.25 9 Activity Info
Psychosis Psychosis is a loose description of an amalgamation of psychological symptoms resulting in a loss of contact with reality. It is thought that although ... Read the Article 1.25 8 Activity Info
Pulseless Electrical Activity Pulseless electrical activity (PEA), also known as electromechanical dissociation, is a clinical condition characterized by unresponsiveness and impal ... Read the Article 1.25 8 Activity Info
QT Prolonging Drugs The heart has an electrical system that allows it to contract in a rhythm. A key aspect of this electrical system is depolarization and repolarization ... Read the Article 1 6 Activity Info
Quinolones Quinolones are a class of broad-spectrum antibiotics used in the management and treatment of many different bacterial infections. This activity review ... Read the Article 1 7 Activity Info
Red Man Syndrome Red man syndrome (RMS) is an anaphylactoid reaction caused by the rapid infusion of the glycopeptide antibiotic vancomycin. RMS consists of a pruritic ... Read the Article 1.25 8 Activity Info
Regular Insulin Regular insulin is a medication used in the management of Diabetes Mellitus and hyperglycemia of a variety of etiologies. It is in the short-acting in ... Read the Article 1.25 8 Activity Info
REM Sleep Behavior Disorder Rapid eye movement (REM) sleep behavior disorder is a parasomnia in which affected individuals act out their dreams while in the REM stage of sleep. U ... Read the Article 1 5 Activity Info
Reverse Transcriptase Inhibitors Reverse transcriptase inhibitors are medications used in the management and treatment of HIV. It is in the antiretroviral class of drugs. This activit ... Read the Article 1 5 Activity Info
Reye Syndrome Reye syndrome is a rare and potentially fatal pediatric illness defined as acute noninflammatory encephalopathy with fatty liver failure. Australian p ... Read the Article 1 7 Activity Info
Rifampin Rifampin is a medication used in the management and treatment of various mycobacterial and gram-positive bacterial infections. It belongs to the antim ... Read the Article 1.25 13 Activity Info
Ritonavir Ritonavir is a protease inhibitor used for the treatment of HIV/AIDS. It is seldom employed for its own antiviral activity but instead serves as a boo ... Read the Article 1.25 9 Activity Info
Rivaroxaban Rivaroxaban is used for treatment and management venous thromboembolism as a postoperative thromboprophylaxis for patients undergoing orthopedic surge ... Read the Article 1 6 Activity Info
Rivastigmine Rivastigmine is a medication used in the management and treatment of neurodegenerative disease, specifically dementia in Alzheimer patients and Parkin ... Read the Article 1 5 Activity Info
Rodenticide Toxicity Rodenticides or “rat poisons” are mixed compounds used to eradicate rodents. They are one of the most toxic agents commonly found in households. Histo ... Read the Article 1 5 Activity Info
Ropivacaine Ropivacaine is FDA-approved for surgical anesthesia and acute pain management. It is used in an epidural block for surgery—such as cesarean sections. ... Read the Article 1 8 Activity Info
Salicylates Toxicity Salicylate toxicity is a medical emergency. Intentional ingestion or accidental overdose can cause severe metabolic derangements, making treatment dif ... Read the Article 1.25 13 Activity Info
Salicylic Acid (Aspirin) Salicylates have been available since the early 1900s. This activity outlines the indications, mechanism of action, methods of administration, importa ... Read the Article 1.5 18 Activity Info
Salmeterol Salmeterol is a medication used in the management and treatment of asthma and COPD. It is in the beta-2 adrenergic agonist class medications. This act ... Read the Article 1 6 Activity Info
Scopolamine Scopolamine is a medication used in the management and treatment of postoperative nausea and vomiting (PONV) and motion sickness. It is in the anticho ... Read the Article 1.25 10 Activity Info
Selective Beta-1-Blockers The cardio-selective beta-1-blockers include atenolol, betaxolol, bisoprolol, esmolol, acebutolol, metoprolol, and nebivolol. FDA approved uses of bet ... Read the Article 1 4 Activity Info
Selective Serotonin Reuptake Inhibitor Toxicity Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed antidepressants. Other clinical indications for SSRI use include anxiety disor ... Read the Article 1 7 Activity Info
Selenium Selenium is a trace metal supplement used in the management and treatment of selenium deficiency. This activity reviews the indications, contraindicat ... Read the Article 1 5 Activity Info
Serotonin Syndrome Serotonin syndrome is a potentially life-threatening condition precipitated by the use of serotonergic drugs. It may be a consequence of therapeutic m ... Read the Article 1.5 15 Activity Info
Sevoflurane Sevoflurane is a halogenated inhalational anesthetic that is FDA approved for the induction and maintenance of general anesthesia in adults and pediat ... Read the Article 1 5 Activity Info
Shellfish Allergy Shellfish allergies can occur due to immunologic or non-immunological processes, and individuals may react to crustaceans, such as crab or shrimp, or ... Read the Article 1 3 Activity Info
Sildenafil Sildenafil is a medication used in the management and treatment of erectile dysfunction and pulmonary arterial hypertension. It is in the phosphodiest ... Read the Article 1.25 11 Activity Info
Sodium Bicarbonate Sodium bicarbonate is a medication used in the management and treatment of multiple disease pathologies. It is a general chemical compound by classifi ... Read the Article 1 5 Activity Info
Sodium Channel Blocker Toxicity Medications that act by sodium channel blockade have a wide variety of clinical applications. Broadly they include Vaughn Williams Class 1 antiarrhyth ... Read the Article 1 4 Activity Info
Sodium Nitroprusside Sodium nitroprusside is a medication used in the management of acute hypertension. It is a potent vasodilator and is administered as an IV infusion wi ... Read the Article 1.25 11 Activity Info
Sodium Oxybate Sodium oxybate is a medication used in the management and treatment of narcolepsy with cataplexy or excessive daytime sleepiness. It is a Central Nerv ... Read the Article 1 6 Activity Info
Spinal Opioids In Anesthetic Practice Spinal opioids for use in anesthesia offers several advantages to systemic pain management. This occurs mainly through the mechanism of action when pl ... Read the Article 1.5 12 Activity Info
St. John's Wort St. John's Wort (Hypericum perforatum) is an invasive, flowering plant native to Europe and Asia. It is also known as Amber, Goatweed, Hardhay, and o ... Read the Article 1 7 Activity Info
Statin Medications Statin medications are used in the management and treatment of hypocholesteremia. They are known to be inhibitors of the hydroxymethylglutaryl-CoA red ... Read the Article 1 7 Activity Info
Stevens Johnson Syndrome Stevens-Johnson syndrome and toxic epidermal necrolysis are acute, rare and potentially fatal skin reactions involving loss of skin and in some cases ... Read the Article 1.5 14 Activity Info
Stimulants The term stimulants cover a broad class of drugs that increase the activity of the central nervous system. These drugs are used by a very high percent ... Read the Article 1 6 Activity Info
Strychnine Toxicity Strychnine has been used for years as a medicinal remedy for a broad range of complaints. Strychnine is responsible for inhibiting postsynaptic glycin ... Read the Article 1 5 Activity Info
Succinic Semialdehyde Dehydrogenase Deficiency Succinic semialdehyde dehydrogenase (SSADH) deficiency is an autosomal recessive-inherited inborn error of metabolism with rare occurrence. Although i ... Read the Article 1 4 Activity Info
Succinylcholine Chloride Succinylcholine chloride is a short-acting depolarizing neuromuscular blockade that is approved by the United States Food and Drug Administration (FDA ... Read the Article 1 5 Activity Info
Sulindac Sulindac is a medication used in a host of conditions. This activity reviews the indications, contraindications, activity, adverse events, and other k ... Read the Article 1 5 Activity Info
Sympathomimetic Toxicity Stimulants have been abused for hundreds, if not thousands, of years because they can increase a person's ability to maintain focus and work for longe ... Read the Article 1 5 Activity Info
Sympathomimetics Sympathomimetics are a classification of medication used in the management and treatment of cardiovascular pathology, hypersensitivity, COPD, and glau ... Read the Article 1.25 9 Activity Info
Tamoxifen Tamoxifen is indicated for the treatment of breast cancer in a variety of settings. It should be noted that evidence suggests that patients with estro ... Read the Article 1.25 10 Activity Info
Tetanus Tetanus is an infection characterized by muscle spasms and lockjaw, also called trismus. Toxins produced by Clostridium tetani are responsible for the ... Read the Article 1.5 16 Activity Info
Tetracaine Tetracaine is an amino-ester class local anesthetic. It has been in use for a variety of purposes since the early 1930s, but its most common use today ... Read the Article 1 5 Activity Info
Tetrahydrocannabinol (THC) THC or Tetrahydrocannabinol is the major psychoactive component and one of the 113 cannabinoids recognized in cannabis. A synthetic formulation of THC ... Read the Article 1 6 Activity Info
Tetrodotoxin Toxicity Tetrodotoxin is a neurotoxin most commonly found in marine animals. It is famous for causing perioral numbness in consumers of pufferfish. Because the ... Read the Article 1 4 Activity Info
Thalidomide Thalidomide is a medication used in the management and treatment of advanced leprosy and multiple myeloma as well as various other solid and hematolog ... Read the Article 1 5 Activity Info
Thallium Toxicity Thallium is a tasteless, odorless, and water-soluble chemical element for which both accidental intoxication and criminal poisoning have been reported ... Read the Article 1 5 Activity Info
Theophylline Theophylline is a medication used in the treatment of asthma and chronic obstructive pulmonary disease as a second-line drug. It is a bronchodilator. ... Read the Article 1 4 Activity Info
Theophylline Toxicity Around the world, theophylline (1,3-dimethylxanthine) is primarily used as a bronchodilator for patients with asthma and chronic obstructive pulmonary ... Read the Article 1.25 11 Activity Info
Thrombin Thrombin is a topical hemostatic agent used to control and minimize blood loss during surgical procedures, is utilized in conjunction or as an alterna ... Read the Article 1 7 Activity Info
Thymic Hyperplasia Thymic hyperplasia could be true thymic or lymphoid hyperplasia. It is usually found incidentally or could present with compressive symptoms or system ... Read the Article 1 4 Activity Info
Tobramycin Tobramycin is an antibiotic used in the management and treatment of systemic and ocular infections. It is a type of aminoglycoside. This activity desc ... Read the Article 1 6 Activity Info
Topical, Local, and Regional Anesthesia and Anesthetics Nerve impulse transmission occurs when voltage-gated sodium channels on the neuronal membrane open, allowing a massive influx of sodium. This causes m ... Read the Article 1.25 11 Activity Info
Topiramate Topiramate is a medication used in the management and treatment of epilepsy and migraine. It is in the second-generation anti-epileptic drugs class of ... Read the Article 1.25 13 Activity Info
Topiramate And Phentermine Phentermine and extended-release (ER) topiramate have been used separately in a variety of ways. Phentermine was first introduced in 1959 as part of a ... Read the Article 1.25 8 Activity Info
Torsemide Torsemide is a loop diuretic extensively used in the management of heart failure, renal disease, and cirrhosis. Torsemide acts on electrolyte channels ... Read the Article 1 6 Activity Info
Torticollis Torticollis is a common diagnosis, and estimates are that 90 percent of individuals will exhibit at least one episode of torticollis throughout their ... Read the Article 1 7 Activity Info
Toxicodendron Toxicity Toxicodendron toxicity is caused by plants within the Anacardiaceae family. It includes plants such as poison ivy, poison oak, poison sumac and is the ... Read the Article 1 4 Activity Info
Toxicology, V-Series Nerve Agents V-Series nerve agents are organophosphate esters that are used as chemical weapons. They are extremely potent acetylcholinesterase inhibitors. Biologi ... Read the Article 1.25 8 Activity Info
Tramadol Tramadol is an FDA approved medication for pain relief. It has specific indications for moderate to severe pain. It is considered a class IV drug by t ... Read the Article 1 4 Activity Info
Tricyclic Antidepressant Toxicity Tricyclic antidepressants (TCAs) were introduced in the late 1950s for the treatment of depression. With the advent of selective serotonin reuptake in ... Read the Article 1.25 12 Activity Info
Trihexyphenidyl Trihexyphenidyl works as an anticholinergic and is used for the treatment of tremors, spasms, stiffness, and weak muscle control seen in patients with ... Read the Article 1 5 Activity Info
Tuberculosis Tuberculosis (TB) is a human disease caused by Mycobacterium tuberculosis. It mainly affects the lungs, making pulmonary disease the most common prese ... Read the Article 1.75 21 Activity Info
Tumor Necrosis Factor Inhibitors Tumor necrosis factor (TNF)-alpha inhibitors, including etanercept (E), infliximab (I), adalimumab (A), certolizumab pegol (C) and golimumab (G), are ... Read the Article 1.25 8 Activity Info
Valproate Toxicity Valproate is a commonly prescribed anticonvulsant used in the treatment of seizure and bipolar disorders. Valproate has also been utilized for the tre ... Read the Article 1.25 7 Activity Info
Varenicline Smoking is a leading cause of morbidity and mortality in the human population and poses as one of the most modifiable risk factors towards preventing ... Read the Article 1 6 Activity Info
Vecuronium Vecuronium bromide is an FDA approved peripherally acting, monoquarternary, steroidal, non-depolarizing neuromuscular blocker with an intermediate dur ... Read the Article 1 4 Activity Info
Verapamil The Food and Drug Administration (FDA) approved indications for verapamil include angina (chronic stable, vasospastic or Prinzmetal variant), unstable ... Read the Article 2 27 Activity Info
Vigabatrin Vigabatrin is a medication used in the management and treatment of infantile spasms and refractory complex partial seizures. It is in the anti-epilept ... Read the Article 1 5 Activity Info
Vinca Alkaloid Toxicity Vinca alkaloids, which belong to a class of cell cycle phase M specific anti-tubulin agents are one of the first plant alkaloids to be developed for u ... Read the Article 1 6 Activity Info
Vincristine Vincristine belongs to a group of drugs known as the vinca alkaloids. Vinca alkaloids are organic compounds made up of carbon, hydrogen, nitrogen, and ... Read the Article 1.25 12 Activity Info
Vinyl Chloride Toxicity Vinyl chloride monomer (VCM) is an IARC group 1 carcinogen known to cause hepatic angiosarcoma (HAS) in highly exposed industrial workers. VCM is a co ... Read the Article 1 4 Activity Info
Violent Patients Violence in healthcare is a worldwide and critical issue. In 2017, the Bureau of Labor and Statistics reported that healthcare workers are five times ... Read the Article 1 5 Activity Info
Vitamin A Toxicity Vitamin A toxicity can due to either topical or oral vitamin A administration. Oral vitamin A toxicity can be acute, due to the ingestion of a large a ... Read the Article 1 6 Activity Info
Vitamin B2 (Riboflavin) Riboflavin is a medication used in the management and treatment of deficiency of vitamin B2. It is part of the B complex group of vitamins. This activ ... Read the Article 1 6 Activity Info
Vitamin B6 (Pyridoxine) Pyridoxine is a vitamin and a medication used in the treatment of vitamin B6 deficiency, as well as the management of nausea and vomiting of pregnancy ... Read the Article 1 7 Activity Info
Vitamin B6 Toxicity This activity describes the toxicity associated with vitamin B6 at higher doses. It explains in detail the pathophysiology and toxicokinetics of vitam ... Read the Article 1 5 Activity Info
Vitamin C (Ascorbic Acid) Vitamin C is a water-soluble vitamin, antioxidant, and essential co-factor for collagen biosynthesis, carnitine and catecholamine metabolism, and diet ... Read the Article 1 5 Activity Info
Vitamin C Deficiency Vitamin C deficiency, also known as scurvy, is a disease primarily associated with socioeconomic status and access to food. Signs and symptoms are oft ... Read the Article 1.5 15 Activity Info
Vitamin E Toxicity Vitamin E toxicity can cause major bleeding events. These can be serious, including the potential for intracranial hemorrhage. To avoid the morbidity ... Read the Article 1 5 Activity Info
Vitamin K Vitamin K is a medication used in the management and treatment of bleeding due to the coagulation disorder caused by warfarin and vitamin K deficiency ... Read the Article 1 5 Activity Info
Warfarin Warfarin is a medication used in the prophylaxis and treatment of venous thrombosis and thromboembolic events. It is in the anticoagulant class of dru ... Read the Article 1.75 25 Activity Info
Warfarin Toxicity Warfarin is a vitamin K antagonist used as an anticoagulant used for treatment and prevention of a variety of coagulopathic and thromboembolic disorde ... Read the Article 1.5 14 Activity Info
Withdrawal Syndromes Withdrawal from drugs and alcohol is a common medical problem. Presentation may vary based on the frequency, duration, and quantity that was typically ... Read the Article 1.25 8 Activity Info
Zinc Zinc is a medication used in the management and treatment of diarrhea. It is in the mineral and supplemental class of drugs. This activity outlines th ... Read the Article 1 5 Activity Info
Zinc Toxicity Zinc is an important cofactor in the body and is essential for normal function; however, increased levels of zinc can become toxic. There are three ty ... Read the Article 1 5 Activity Info
Ziprasidone Ziprasidone is an atypical antipsychotic used to treat schizophrenia, bipolar mania, and acute agitation in schizophrenic patients. Because it antagon ... Read the Article 1 7 Activity Info
Zolmitriptan Zolmitriptan is a medication used in the management and treatment of acute migraine. It is in the triptan class of drugs. This activity describes the ... Read the Article 1 6 Activity Info
Zolpidem Zolpidem is a non-benzodiazepine receptor modulator primarily used in the FDA approved short-term treatment of insomnia aimed at patients with difficu ... Read the Article 1 4 Activity Info

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