Topiramate and Phentermine

Overview

4.6 out of 5 (37 Reviews)

Credits

1.50

Post Assessment Questions

7

Start Date

1 Sep 2023

Last Review Date

1 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes


 
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Activity Description

Phentermine and extended-release (ER) topiramate have been used separately in various ways. Phentermine was first introduced in 1959 as part of an anti-obesity combination drug. Topiramate was released for commercial use in 1996. Phentermine on its own has been used for short-term treatment of obesity in combination with exercise and caloric restriction. In addition, Topiramate has been used to treat partial-onset or primary generalized tonic-clonic seizures, Lennox-Gastaut syndrome, and as a prophylactic treatment of migraine headaches. The United States Food and Drug Administration approved the combination of these two drugs in 2012 to treat obesity. The drugs are to be used in combination with a reduced-calorie diet and exercise program in individuals with an initial body mass index (BMI) over 30 kg/m2 or those with a BMI of over 27 in combination with at least one obesity-related comorbidity. This activity outlines the indications, mechanism of action, methods of administration, important adverse effects, contraindications, toxicity, and monitoring, of topiramate/phentermine so providers can direct patient therapy where they are indicated as part of the interprofessional team.

UAN: JA4008338-0000-23-5003-H01-P

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Describe the mechanisms of action of topiramate and phentermine.
  • Outline the indications for initiating topiramate/phentermine therapy in a weight loss regimen.
  • Review the adverse events profile for topiramate/phentermine combination therapy.
  • Summarize interprofessional team strategies for improving care coordination and communication to properly use topiramate/phentermine combination therapy to improve patient outcomes as part of a weight-loss regimen.

Pharmacy Activity Type:
Disease/Drug Therapy Related


Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Pharmacists: StatPearls, LLC designates this activity for a maximum of 1.50 ACPE credit(s). (UAN: JA4008338-0000-23-5003-H01-P ). Pharmacists should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Rana M. on 2/26/2021

Ashley T. on 9/11/2021

Lauren C. on 9/12/2021

Molly D. on 2/21/2022

Darren T. on 4/5/2022

Lori N. on 4/16/2022

Elina R. on 4/20/2022

Janet M. on 5/4/2022

Jesus m. on 5/11/2022

Lacey S. on 5/22/2022

Amy D. on 8/9/2022

Keren A. on 8/10/2022

Alex N. on 8/30/2022

Johnny L. on 9/21/2022

jeffrey t. on 12/7/2022

Mace S. on 1/29/2023

Kelli T. on 5/19/2023

Jamie J. on 2/24/2023

Lisa B. on 4/3/2023

Brian H. on 4/4/2023

Maureen W. on 5/24/2023

Brett F. on 5/30/2023

none

Mary R. on 7/23/2023

Hannah B. on 7/26/2023

Alison S. on 8/29/2023

Karen B. on 9/23/2023

Heather U. on 10/4/2023

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Wassim E. on 2/17/2024

Kristi S. on 2/25/2024

William L. on 2/27/2024

ALI O. on 3/15/2024

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