Overview

4.7 out of 5 (15 Reviews)

Credits

1.00

Post Assessment Questions

6

Start Date

1 Sep 2023

Last Review Date

25 Feb 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


 
Need Help?  If you have a system or content concerns, please contact support@statpearls.com

Activity Description

Triptans comprise a class of medications approved by the US Food and Drug Administration (FDA) as the first-line agent for treating acute migraine episodes with or without aura. In the United States, 7 triptans are available in diverse dosage formulations, including sumatriptan, naratriptan, zolmitriptan, rizatriptan, almotriptan, frovatriptan, and eletriptan. Sumatriptan, in its subcutaneous formulation, is also approved for treating cluster headaches. Almotriptan has an FDA indication for use in adolescents for treating migraines lasting at least 4 hours. The FDA has also approved zolmitriptan nasal spray for children aged 12 or older and rizatriptan for children aged 6 to 17. Frovatriptan, naratriptan, and oral zolmitriptan have off-label uses for preventing menstrual migraine.

When triptans bind to the neurogenic and central 5-serotonin receptors, they inhibit the release of vasoactive neuropeptides by inhibiting trigeminal nerve activation and blocking the transmission of pain signals to the brain. The binding of triptans to the vascular 5-HT1B receptors leads to vasoconstriction of the cranial arteries, which painfully dilate during a migraine attack. This activity reviews the indications, mechanisms of action, adverse event profile, and contraindications of different triptans as essential components in migraine therapy. This activity involves participating clinicians reviewing the best practice collaboration among primary or emergency care and consulting neurologists to enhance patient outcomes.


UAN: JA4008338-0000-23-4631-H01-P

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify patients who are appropriate candidates for triptan therapy based on established migraine diagnosis and severity.

  • Screen patients for contraindications to triptan therapy, including but not limited to severe hepatic or renal impairment, cardiovascular disease, and uncontrolled hypertension.

  • Select the most suitable triptan formulation and dosage for each patient based on their preferences, tolerability, and treatment goals.

  • Collaborate with other healthcare providers to discuss the benefits, risks, and proper use of triptan therapy with patients, thereby optimizing triptan therapy and comprehensive migraine management.

Pharmacy Activity Type:
Disease/Drug Therapy Related


Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Pharmacists: StatPearls, LLC designates this activity for a maximum of 1.00 ACPE credit(s). (UAN: JA4008338-0000-23-4631-H01-P ). Pharmacists should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

David Y. on 10/6/2021

Lisa R. on 1/29/2022

Rebecca I. on 5/12/2022

cyvada s. on 5/16/2022

Howard K. on 6/3/2022

BURTON L. on 7/15/2022

hary a. on 10/17/2022

david h. on 11/23/2022

Kelli M. on 12/22/2022

Dr M. on 12/29/2022

VLADIMIR E. on 6/23/2023

Michael M. on 11/28/2023

Stacey S. on 1/10/2024

Michelle S. on 1/22/2024

David S. on 3/22/2024

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