Overview

4 out of 5 (1 Reviews)

Credits

1.00

Post Assessment Questions

6

Start Date

1 Sep 2023

Last Review Date

12 Nov 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


 
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Activity Description

Neomycin is primarily used to treat and manage hepatic coma and perioperative prophylaxis. Neomycin belongs to the aminoglycosides group of antibiotics, which functions by inhibiting bacterial protein synthesis, resulting in a bactericidal effect primarily against gram-negative bacteria. When administered orally, neomycin exhibits limited absorption into the systemic circulation. This characteristic enhances its effectiveness for treating infections localized within the gastrointestinal tract. Neomycin's mechanism of action closely resembles that of most aminoglycosides, as it binds to the 30S ribosomal subunit, thereby disrupting bacterial protein synthesis. The initial steps required for peptide synthesis proceed without interruption, but the subsequent elongation process is hindered due to the disruption of translational accuracy. This interference disrupts the bacteria's translation process, ultimately resulting in the bactericidal effects of the medication. This activity highlights neomycin's indications, contraindications, mechanisms of action, and adverse drug reactions within the clinical context, focusing on essential information for interprofessional healthcare team members. This activity also reviews crucial facets related to neomycin therapy, including off-label uses, appropriate dosing, pharmacokinetics, monitoring, and relevant interactions, which enhance the competence of healthcare providers when caring for patients with hepatic coma, perioperative prophylaxis, constipation-dominant inflammatory bowel syndrome, associated disorders, and their consequences.


UAN: JA4008338-0000-23-3111-H01-P

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the appropriate indications for neomycin use, including hepatic coma and perioperative prophylaxis, considering patient-specific factors.

  • Differentiate between neomycin and other antibiotics by understanding its unique mechanism of action involving 30S ribosomal subunit binding, bactericidal effect on gram-negative bacteria, and low gastrointestinal absorption.

  • Assess the renal function of patients before and during neomycin therapy to monitor potential nephrotoxicity.

  • Communicate effectively with patients about the rationale for neomycin treatment, explaining the drug's potential risks and expected outcomes.

Pharmacy Activity Type:
Disease/Drug Therapy Related


Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Pharmacists: StatPearls, LLC designates this activity for a maximum of 1.00 ACPE credit(s). (UAN: JA4008338-0000-23-3111-H01-P ). Pharmacists should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Mary Y. on 5/11/2022

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