Antiemetic Neurokinin-1 Receptor Blockers

Overview

4.3 out of 5 (30 Reviews)

Credits

1.00

Post Assessment Questions

6

Start Date

1 Sep 2023

Last Review Date

11 Jan 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


 
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Activity Description

Neurokinin-1 (NK-1) receptor antagonists are antiemetic drugs with unique anxiolytic, antidepressant, and antiemetic properties. The discovery of NK-1 receptor blockers was crucial in preventing emesis associated with cancer chemotherapy. The NK-1 receptor antagonist competitively binds to the NK-1 receptor, thereby blocking the binding of substance P and preventing the transmission of the emetic signal. This activity reviews the indications, contraindications, mechanism of action, adverse event profile, and other crucial aspects of antiemetic NK-1 receptor blockers within the clinical setting. This activity also focuses on essential information required by members of an interprofessional team responsible for treating patients who stand to benefit therapeutically from these agents.


UAN: JA4008338-0000-23-524-H01-P

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify appropriate candidates for neurokinin-1 receptor antagonists based on their understanding of the patient's chemotherapy regimen and emetogenic risk.

  • Apply knowledge of neurokinin-1 receptor antagonists in diverse clinical scenarios, tailoring treatment approaches to individual patient needs and characteristics.

  • Select the most appropriate neurokinin-1 receptor antagonist based on patient-specific factors, treatment goals, and potential drug interactions.

  • Collaborate with other interprofessional healthcare teams, such as pharmacists and nurses, optimizing the use of neurokinin-1 receptor antagonists to achieve the best outcomes in managing chemotherapy-induced nausea and vomiting.

       

Pharmacy Activity Type:
Disease/Drug Therapy Related


Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Pharmacists: StatPearls, LLC designates this activity for a maximum of 1.00 ACPE credit(s). (UAN: JA4008338-0000-23-524-H01-P ). Pharmacists should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Laura C. on 6/25/2021

Christopher C. on 8/30/2021

Suzanne P. on 3/1/2022

Zoe M. on 7/26/2022

Kari B. on 8/5/2022

Nice

Kenneth R. on 11/2/2022

Anna B. on 12/3/2022

Lauren K. on 12/5/2022

Peter S. on 1/4/2023

Scott C. on 1/14/2023

Dakota P. on 2/15/2023

Russell R. on 3/1/2023

James S. on 3/25/2023

Deanne N. on 4/15/2023

shahid i. on 8/19/2023

Good CME series

Douglas B. on 9/2/2023

Kira M. on 9/8/2023

Richard D. on 9/23/2023

Genevieve M. on 10/11/2023

Essam M. on 10/21/2023

Ann C. on 10/30/2023

ROBERT Z. on 12/20/2023

Hedy M. on 12/29/2023

Tina S. on 1/16/2024

Steven F. on 1/21/2024

Kelly K. on 2/10/2024

Elizabeth B. on 3/14/2024

karin p. on 3/22/2024

Maren E. on 4/12/2024

Theresa J. on 4/15/2024

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