NP-Advanced Pathophysiology CE

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All of our activities are approved by AANP (ARNP) and all activity is reported to CE Broker and all states as required. StatPearls continuing education activities are linked to practice questions which are based on the Nurse Practitioner Board and Certification content outlines. 320 authors and 7 editors have contributed to the development of the NP-Advanced Pathophysiology content, which is continuously refined and updated to improve your learning experience.

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NP-Advanced Pathophysiology Activities

Title Description Hours Questions
Abdominal Abscess Abdominal abscesses contain cellular debris, enzymes, and liquid and can be from an infectious or non-infectious source. They are a common and serious ... Read the Article 1 7 Activity Info
Abdominal Angina Abdominal angina is postprandial pain that occurs in mesenteric vascular occlusive disease when blood flow to the colon is unable to meet visceral dem ... Read the Article 1 5 Activity Info
Abnormal Respirations There are multiple types of normal and abnormal respiration. They include apnea, eupnea, orthopnea, dyspnea hyperpnea, hyperventilation, hypoventilati ... Read the Article 1.25 10 Activity Info
Acne Conglobata Acne conglobata is a rare but severe form of acne. It usually presents with deep burrowing abscesses that interconnect with each other. Scar formation ... Read the Article 1.25 13 Activity Info
Acquired Angioedema Angioedema is characterized by one or more areas of well-demarcated, non-pitting edema of deep subcutaneous tissues. It is primarily known to involve ... Read the Article 1 5 Activity Info
Acromioclavicular Joint Injury Acromioclavicular joint injuries account for more than forty percent of all shoulder injuries. Mild injuries are not associated with any significant ... Read the Article 1.25 9 Activity Info
Acute Kidney Injury Acute kidney injury, previously known as acute renal failure, denotes a sudden and often reversible reduction in the kidney function, as measured by ... Read the Article 1.5 17 Activity Info
Acute Myocardial Infarction Acute myocardial infarctions are one of the leading causes of death in the developed world, with prevalence approaching three million people worldwide ... Read the Article 2 30 Activity Info
Acute Myocarditis Acute myocarditis is inflammation of the myocardium. It is typically seen in infants and teenagers but can occur at any age. It most commonly results ... Read the Article 1 5 Activity Info
Acute Otitis Media Acute otitis media (AOM) is defined as an infection of the middle ear and is the second most common pediatric diagnosis in the emergency department fo ... Read the Article 1.5 13 Activity Info
Acute Pancreatitis Acute pancreatitis is the leading cause of gastrointestinal-related hospitalization in the United States, and its frequency continues to rise in the U ... Read the Article 2.25 34 Activity Info
Acute Pulmonary Embolism Acute pulmonary embolism is a common clinical condition with a variable clinical presentation, making its diagnosis challenging. This activity outline ... Read the Article 2.25 31 Activity Info
Acute ST Elevation Myocardial Infarction An acute ST-elevation myocardial infarction occurs due to occlusion of one or more coronary arteries, causing transmural myocardial ischemia which in ... Read the Article 1 7 Activity Info
Acute Stroke Acute strokes, also known as cerebrovascular accidents, are broadly classified as either ischemic or hemorrhagic. Acute strokes result in loss of bloo ... Read the Article 2 28 Activity Info
Addison Disease Addison disease is a relatively rare condition, which can have devastating consequences if not promptly recognized and appropriately treated. Often th ... Read the Article 2 28 Activity Info
Adenoviruses The adenoviruses are DNA viruses common in animals and humans, occurring frequently in both adults and children. There are more than 100 serologically ... Read the Article 1 6 Activity Info
Adult Diabetic Ketoacidosis Diabetic ketoacidosis (DKA) is characterized by uncontrolled hyperglycemia, metabolic acidosis, and increased body ketone concentration. It is a life- ... Read the Article 1.25 11 Activity Info
Alcohol and Substance Abuse Evaluation and Treatment in American Indians and Alaska Natives Alaskan Natives and American Indians comprise a diverse population with a distinct variation in alcohol and substance abuse rates due to geographic lo ... Read the Article 1 5 Activity Info
Alcohol Use Disorder Alcohol use disorder is very common in the United States. The cause of alcohol use disorder is not well understood; however, several factors are thou ... Read the Article 1.75 23 Activity Info
Allergic And Environmental Induced Asthma Asthma is a major cause of morbidity and mortality in the United States. Numerous studies have shown that early institution of inhaled corticosteroids ... Read the Article 1.25 7 Activity Info
Alpha Thalassemia Hemoglobin H disease (alpha-thalassemia) can be found in patients that live in areas with a high incidence of malaria. Symptoms at presentation, such ... Read the Article 1.25 8 Activity Info
Alzheimer Disease Alzheimer disease (AD) is the most common cause of a decline in cognitive ability. It is a neurodegenerative disorder that usually affects people over ... Read the Article 2 27 Activity Info
Anemia Of Chronic Renal Disease Anemia of chronic renal disease, also known as anemia of chronic kidney disease (CKD), is a form of normocytic, normochromic, hypoproliferative anemia ... Read the Article 1.25 9 Activity Info
Anterior Cerebral Artery Stroke Anterior cerebral artery strokes occur in the territory of the anterior cerebral artery which involves the superior and medial part of the parietal lo ... Read the Article 1.25 12 Activity Info
Anterior Myocardial Infarction Anterior myocardial infarction (AMI) is a common heart disease associated with significant mortality and morbidity. Advancement in diagnosis and treat ... Read the Article 1 7 Activity Info
Appendicitis Appendicitis is the inflammation of the vermiform appendix. It typically presents acutely, within 24 hours of onset, but can also present as a more ch ... Read the Article 2 28 Activity Info
Asbestosis Asbestosis is an interstitial lung disease caused by the inhalation of asbestos fibers. Asbestos fibers have been historically chosen for construction ... Read the Article 1.25 10 Activity Info
Asthma Asthma is a chronic disease of the air passages characterized by inflammation and narrowing of the airways. Symptoms of asthma include shortness of br ... Read the Article 2.25 32 Activity Info
Asthma In Pregnancy Bronchial asthma (BA) is considered the most common chronic disease in pregnancy, complicating 4% to 8% of pregnancies. Bronchial asthma exacerbation ... Read the Article 1.25 8 Activity Info
Asthma Medication in Children Asthma typically presents with a history of respiratory symptoms such as wheezing, shortness of breath, chest tightness and cough, and is characterize ... Read the Article 1.25 9 Activity Info
Atrial Myxoma Myxomas are the most common primary cardiac tumor. It is estimated that more than 75% of myxomas originate in the left atrium either at the mitral ann ... Read the Article 1.5 14 Activity Info
Atrioventricular Block Atrioventricular (AV) conduction is evaluated by assessing the relationship between the P waves and QRS complexes. Normally, there is a P wave that pr ... Read the Article 1.25 9 Activity Info
Atypical Antipsychotic Effect On Bone Mineral Density Atypical antipsychotic use in psychiatric patients, particularly children and adolescents (C/A), has increased recently. Autism spectrum, bipolar, ps ... Read the Article 1 5 Activity Info
Bacterial Pneumonia The word "pneumonia" originates from the ancient Greek word "pneumon," which means "lung," so the word "pneumonia" becomes "lung disease." Medically i ... Read the Article 2 27 Activity Info
Barrett Esophagus Barrett esophagus (BE) is a pre-malignant condition characterized by conversion of the normal esophageal squamous epithelium into metaplastic columnar ... Read the Article 1.5 15 Activity Info
Biliopancreatic Diversion With Duodenal Switch The biliopancreatic diversion was first described by Scorpinaro in 1979. This procedure combined a horizontal gastric resection with the closure of a ... Read the Article 1.25 7 Activity Info
Binge Eating Disorder Binge eating disorder is an eating disorder associated with various psychological and non-psychological issues with some degree of impairment of daily ... Read the Article 1.25 11 Activity Info
Blood Transfusion Blood transfusions are a relatively common medical procedure and while typically safe, there are multiple complications that practitioners need to be ... Read the Article 2.25 32 Activity Info
Breast Abscess Breast abscesses are a common problem, especially in lactating women. Most breast abscesses are benign. However, when a non-lactating patient presents ... Read the Article 1.25 10 Activity Info
Breast Cancer Breast cancer is the most common cancer diagnosed in women, accounting for more than 1 in 10 new cancer diagnoses each year. It is the second most com ... Read the Article 2 28 Activity Info
Breast Fibroadenoma A breast fibroadenoma is a painless, unilateral, benign tumor that presents as a solid lump. It commonly occurs in women between the age of 14 to 35 y ... Read the Article 1.5 17 Activity Info
Breast Milk Jaundice Breast milk jaundice is a type of jaundice that occurs in neonates due to breastfeeding. It happens within the first week of life due to the abnormal ... Read the Article 1.25 12 Activity Info
Buerger Disease Buerger disease is a nonatherosclerotic, progressive, segmental inflammatory disease affecting the small and medium-sized arteries of upper and lower ... Read the Article 1 7 Activity Info
Caloric Testing Caloric testing is a useful clinical tool that can assess and quantify the functional status of the individual vestibular systems. The test utilizes t ... Read the Article 1 5 Activity Info
Cardiac Cancer Cardiac tumors are uncommon and can be primary or metastatic. Primary cardiac tumors are rare, and the incidence is from 0.001 to 0.3% by autopsy. The ... Read the Article 1.25 8 Activity Info
Cardiac Cirrhosis Cardiac cirrhosis is a term used to include the spectrum of hepatic disorders that occur secondary to hepatic congestion due to cardiac dysfunction, e ... Read the Article 1 6 Activity Info
Cardiac Syncope Syncope, a sudden, transient loss of consciousness and postural tone, is a phenomenon estimated to affect 30% to 40% of the population, and those numb ... Read the Article 1 6 Activity Info
Carotid Artery Dissection Carotid artery dissection is a condition whereby the layers of the carotid artery are spontaneously separated. This potentially compromises blood flow ... Read the Article 1.25 9 Activity Info
Cellulitis Cellulitis is a common bacterial skin infection, with over 14 million cases occurring in the United States annually. This activity educates the learne ... Read the Article 1.25 13 Activity Info
Central Pontine Myelinolysis Central pontine myelinolysis is a rare neurologic condition most frequently caused by the rapid correction of hyponatremia. This activity reviews the ... Read the Article 1.25 10 Activity Info
Childhood Brain Tumors Pediatric brain tumors are the most common type of solid childhood cancer and only second to leukemia as a cause of pediatric malignancies. They are c ... Read the Article 1.25 9 Activity Info
Chromaffin Cell Cancer Pheochromocytoma is a tumor that arises from chromaffin cells present in the adrenal medulla or paraganglion cells. It can present with vague symptoms ... Read the Article 1.25 10 Activity Info
Chronic Liver Disease Chronic liver disease is a progressive deterioration of liver functions. Liver functions include the production of clotting factors and other proteins ... Read the Article 1.25 7 Activity Info
Chronic Obstructive Pulmonary Disease Chronic obstructive lung disease is a lung disease characterized by lung airflow limitation and can be from exposure to harmful substances. It is a co ... Read the Article 2.25 37 Activity Info
Ciliary Dysfunction The majority of newborns with primary ciliary dysfunction (PCD), formerly known as immotile cilia syndrome, develop neonatal respiratory distress with ... Read the Article 1 5 Activity Info
Comprehensive Review Of Bioterrorism Bioterrorism involves the deliberate release of bioweapons to cause death or disease in humans, animals, or plants. Biological weapons may be develope ... Read the Article 3.25 50 Activity Info
Congestive Heart Failure Heart failure is a complex clinical syndrome in which the heart cannot pump enough blood to meet the body's requirements. It results from any disorder ... Read the Article 2.5 37 Activity Info
Congestive Heart Failure And Pulmonary Edema Heart failure is a growing public health problem and is now the most common cause of hospitalizations in the U.S. among patients 65 years and older. T ... Read the Article 1.5 15 Activity Info
Constrictive Pericarditis The pericardium is the fibroelastic sac that covers the heart. Besides acting as a protective barrier, it also affects cardiac hemodynamics. Constrict ... Read the Article 1.25 12 Activity Info
Contact Urticaria Contact urticaria is a transient wheal and flare response on exposure to specific agents, especially in the work environment. Contact urticaria falls ... Read the Article 1.25 10 Activity Info
Coronary Artery Disease Coronary artery disease is a common heart condition that involves atherosclerotic plaque formation in the vessel lumen. This leads to impairment in bl ... Read the Article 1.5 13 Activity Info
Coronary Artery Disease Prevention In the United States, cardiovascular disease is one of the leading causes of mortality, morbidity, and increased healthcare cost. According to the AHA ... Read the Article 1 6 Activity Info
Crohn Disease Crohn disease (CD) and ulcerative colitis (UC) are two conditions commonly referred to as inflammatory bowel disease (IBD). They are immunologically m ... Read the Article 2.25 34 Activity Info
Cultural Competence In Caring For American Indians and Alaska Natives Cultural competency is emphasized in treating American Indian/ Alaskan Native (AI/AN) patients because the mortality rates are more likely to increase ... Read the Article 1 7 Activity Info
Cushing Syndrome Cushing syndrome is caused by prolonged exposure to high circulating levels of cortisol. The most common cause of cushingoid features is iatrogenic co ... Read the Article 1.75 20 Activity Info
Cutaneous Larva Migrans Cutaneous larva migrans (CLM), also having been termed for the clinical sign of creeping eruption, is an infectious syndrome caused by multiple types ... Read the Article 1 4 Activity Info
Deep Vein Thrombosis A deep-vein thrombosis (DVT) is a blood clot that forms within the deep veins, usually of the leg, but can occur in the veins of the arms and the mese ... Read the Article 1.25 8 Activity Info
Deep Venous Thrombosis Of The Lower Extremity A deep-vein thrombosis (DVT) is a blood clot that forms within the deep veins usually of the leg but can occur in the veins of the arms and the mesent ... Read the Article 1.25 10 Activity Info
Diabetes Insipidus Diabetes insipidus (DI) is a disease process that results in either decreased release of antidiuretic hormone (ADH, also known as vasopressin or AVP) ... Read the Article 1.5 18 Activity Info
Diabetes Mellitus Diabetes mellitus (DM) is a disease of inadequate control of blood levels of glucose. It has many subclassifications, including type 1, type 2, maturi ... Read the Article 2 27 Activity Info
Diabetes Mellitus Type 2 Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia. It may be due to impaired insulin secretion, resista ... Read the Article 2.25 32 Activity Info
Disseminated Intravascular Coagulation Disseminated intravascular coagulation can be defined is a widespread hypercoagulable state that can lead to both microvascular and macrovascular clot ... Read the Article 1.75 22 Activity Info
Dwarfism Dwarfism is the medical terminology for short-stature. It is defined as height-vertex below two standard deviations (-2SD) or in the third percentile ... Read the Article 1 6 Activity Info
ECG T Wave Normally, the T wave on an electrocardiogram (ECG) is representative of ventricular repolarization. Changes in T wave morphology can be indicative of ... Read the Article 1 6 Activity Info
EKG Rhythm Successful ECG interpretation requires the utilization of the same stepwise method with each attempt. Like all aspects of electrocardiographic interpr ... Read the Article 1 7 Activity Info
Emphysema Pulmonary emphysema, a progressive lung disease, is a form of chronic obstructive pulmonary disease (COPD). Global Initiative for Chronic Obstructive ... Read the Article 1.25 8 Activity Info
Endometrial Cancer Uterine endometrial cancer is the most prevalent gynecologic malignancy in American women and a major cause of both morbidity and mortality. Over 60,0 ... Read the Article 2 21 Activity Info
End-Stage Renal Disease More than 500,000 people in the United States live with end-stage renal disease (ESRD). The development of chronic kidney disease (CKD) and its progre ... Read the Article 1.25 9 Activity Info
Erythema Nodosum Erythema nodosum (EN) is a common acute nodular septal panniculitis, characterized by the sudden onset of erythematous, firm, solid, deep nodules or p ... Read the Article 1.25 10 Activity Info
Esophageal Cancer Esophageal cancer is a deadly malignancy with a very low survival, even with treatment. In the United States, esophageal cancers represent the fifth m ... Read the Article 1.25 11 Activity Info
Essential Hypertension The current definition of hypertension (HTN) is systolic blood pressure (SBP) values of 130mmHg or more and/or diastolic blood pressure (DBP) more tha ... Read the Article 1.5 18 Activity Info
Familial Hypercholesterolemia, Type 2A Familial hypercholesterolemia (FH) is an autosomal dominant disorder of lipid metabolism presenting at birth. It is characterized by very high low-den ... Read the Article 1 5 Activity Info
Familial Hyperchylomicronemia Syndrome Familial hyperchylomicronemia syndrome is a rare autosomal recessive metabolic disorder caused by the mutation in lipoprotein lipase. It correlates wi ... Read the Article 1 4 Activity Info
Fibrocystic Breast Disease Fibrocystic breast disease is the most common benign type of breast disease, diagnosed in millions of women worldwide. Certain hormonal factors underp ... Read the Article 1.25 10 Activity Info
Foot Ulcer Foot ulceration is among the most common health issues, and its prevalence has increased recently. It is one of the major causes of amputations, parti ... Read the Article 1.25 8 Activity Info
Gamma-Hydroxybutyrate Toxicity Gamma hydroxybutyrate (GHB) is pharmaceutically manufactured as sodium oxybate for the treatment of narcolepsy. This formulation is considered a Sched ... Read the Article 1 8 Activity Info
Gangrene Gangrene is tissue damage secondary to infection, ischemia, or both. It is a relatively uncommon condition, and early recognition is essential. Gangre ... Read the Article 1.25 7 Activity Info
Gastric Cancer Gastric cancer is the fifth most frequently diagnosed cancer and the third leading cause of cancer deaths worldwide. The only potentially curative tre ... Read the Article 1.75 18 Activity Info
Gastritis The current classification of gastritis is based on time course (acute versus chronic), histological features, anatomic distribution, and underlying p ... Read the Article 1.25 12 Activity Info
Gastroesophageal Reflux Disease Gastroesophageal reflux disease (GERD) is a condition that develops when there is a retrograde flow of stomach contents back into the esophagus. It ca ... Read the Article 2.25 32 Activity Info
Genetics and Obesity Obesity is closely linked to genetics and environmental factors. The newest studies in the field of epigenetics further our understanding of the effec ... Read the Article 1.25 7 Activity Info
Glomerulonephritis The term "glomerulonephritis" encompasses a subset of renal diseases characterized by immune-mediated damage to the basement membrane, mesangium, or t ... Read the Article 1.5 16 Activity Info
Gonorrhea Neisseria gonorrhoeae, an obligate human pathogen, is a sexually transmitted disease that causes consequential worldwide morbidity both in resource-ab ... Read the Article 1.75 21 Activity Info
Goodpasture Syndrome Goodpasture syndrome also referred to as anti-glomerular basement membrane (anti-GBM) disease, is an autoimmune disease that affects both the kidneys ... Read the Article 1.25 11 Activity Info
Gout Gout is one of the most common causes of chronic inflammatory arthritis in the United States, which is characterized by monosodium urate (MSU) monohyd ... Read the Article 1.5 15 Activity Info
Graves Disease Graves' disease is the most common cause of hyperthyroidism. It is a disorder with systemic manifestations that primarily affect heart, skeletal muscl ... Read the Article 1.5 13 Activity Info
Hand and Wrist Rheumatoid Arthritis Rheumatoid arthritis (RA) is an immune-mediated multisystem inflammatory disease that predominantly affects the synovial joints. This activity provide ... Read the Article 1.25 7 Activity Info
Hematuria Hematuria is the presence of blood in the urine. Hematuria can be gross or microscopic; gross hematuria is visible blood in urine whereas microscopic ... Read the Article 1.25 10 Activity Info
Hemophilia A Hemophilia encompasses a group of inherited disorders that alter blood coagulation. Classical hemophilia, also known as hemophilia A, is a hereditary ... Read the Article 1.25 13 Activity Info
Hereditary Nonpolyposis Colon Cancer Hereditary non-polyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is an autosomal dominant disorder. Individuals with HNPCC are at inc ... Read the Article 1 5 Activity Info
Herpes Zoster Herpes zoster, also known as shingles, is a viral syndrome caused by reactivation of the varicella-zoster virus. After an episode of varicella (chicke ... Read the Article 1 6 Activity Info
Herpes Zoster Ophthalmicus Herpes zoster ophthalmicus occurs due to the reactivation of the latent varicella-zoster virus. It is a variation of herpes zoster that can cause a va ... Read the Article 1.25 9 Activity Info
HIV Prophylaxis HIV prophylaxis is divided into two categories: post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP). PEP is the administration of anti ... Read the Article 1 7 Activity Info
Hodgkin Lymphoma Hodgkin lymphoma (HL) is a rare monoclonal lymphoid neoplasm characterized by the following four features: HL usually presents in young adults, common ... Read the Article 1.25 13 Activity Info
Hydrocephalus Hydrocephalus is the symptomatic accumulation of cerebrospinal fluid inside the cerebral ventricles. It has complex pathogenesis and different causes. ... Read the Article 1.5 18 Activity Info
Hypercalcemia Calcium is the most abundant cation found in the human body and plays an integral role in neural transmission, enzyme activity, myocardial function, c ... Read the Article 1.5 18 Activity Info
Hypercortisolism Hypercortisolism refers to the clinical state resulting from excess tissue exposure to cortisol and/or other glucocorticoids. When such exposure is su ... Read the Article 1.5 10 Activity Info
Hyperemesis Gravidarum Hyperemesis gravidarum refers to intractable vomiting during pregnancy, leading to weight loss and volume depletion, resulting in ketonuria and/or ket ... Read the Article 1 5 Activity Info
Hyperthyroidism The thyroid gland is a bilobed structure located in the anterior aspect of the trachea between the cricoid cartilage and the suprasternal notch. Each ... Read the Article 1.75 22 Activity Info
Hyperthyroidism In Pregnancy Hyperthyroidism is an uncommon condition that complicates approximately 0.1% to 0.4% of pregnancies. The condition is marked by increased levels of ci ... Read the Article 1.25 7 Activity Info
Hypoglycemia Hypoglycemia is often defined by a plasma glucose concentration below 70 mg/dL; however, signs and symptoms may not occur until plasma glucose concent ... Read the Article 1.5 18 Activity Info
Hypomagnesemia Magnesium is an important electrolyte. It is a key part of many reactions that occur in the human body, affecting cellular function, nerve conduction, ... Read the Article 1 4 Activity Info
Hyponatremia Hyponatremia is defined as a serum sodium concentration of less than 135 mEq/L but can vary to a small extent in different laboratories. Hyponatremia ... Read the Article 1.25 12 Activity Info
Hypothyroidism Hypothyroidism results from low levels of thyroid hormone with varied etiology and manifestations. The drug of choice for the treatment of hypothyroid ... Read the Article 2 25 Activity Info
Idioventricular Rhythm Idioventricular rhythm is a slow regular ventricular rhythm with a rate of less than 50 bpm, absence of P waves, and a prolonged QRS interval. When th ... Read the Article 1 5 Activity Info
Inferior Myocardial Infarction Without timely treatment, coronary artery occlusion results in decreased perfusion to the myocardium, resulting in myocardial ischemia followed by my ... Read the Article 1.25 11 Activity Info
Inflammatory Bowel Disease Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract and is divided into Crohn disease and ulcerative coli ... Read the Article 1.25 11 Activity Info
Influenza Influenza is a communicable viral disease that affects the upper respiratory tract, including upper and lower respiratory passages. A wide spectrum of ... Read the Article 1.25 9 Activity Info
Iron Iron is a mineral essential to the human body. It is administered for the treatment of iron deficiency. It is available in many formulations that belo ... Read the Article 1.25 8 Activity Info
Ischemic Stroke Cerebrovascular accidents, commonly known as strokes, are prevalent across patient populations and can be a significant cause of morbidity and mortali ... Read the Article 1.5 15 Activity Info
Kawasaki Disease Kawasaki disease (KD) is an acute, self-limited medium vessel vasculitis that has a predilection for the coronary arteries. This activity reviews the ... Read the Article 1.75 19 Activity Info
Ketogenic Diet Despite continuous advances in the medical world, obesity continues to remain a major worldwide health hazard with adult mortality as high as 2.8 mill ... Read the Article 1 6 Activity Info
Lateral Wall Myocardial Infarction Isolated lateral wall myocardial infarction (LMI), similar to other acute myocardial infarctions (MI), is caused by acute atherosclerotic plaque ruptu ... Read the Article 1 7 Activity Info
Liddle Syndrome Liddle syndrome is one of the rare causes of resistant hypertension that presents in early childhood. Grant Liddle et al. first explained Liddle syndr ... Read the Article 1 4 Activity Info
Listeria Monocytogenes Listeria monocytogenes is a facultative, intracellular, gram-positive rod that is responsible for causing the infection listeriosis. Listeria causes s ... Read the Article 1.25 13 Activity Info
Lung Cancer Lung cancer or bronchogenic carcinoma refers to tumors originating in the lung parenchyma or within bronchi. It is one of the leading causes of cancer ... Read the Article 2.25 30 Activity Info
Lyme Disease Lyme disease is an infectious disease caused by Borrelia burgdorferi, which is spread by ticks. Lyme disease is divided into three stages: early local ... Read the Article 1.75 21 Activity Info
Malignant Melanoma A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, ... Read the Article 1.5 17 Activity Info
Mania Mania is a period of 1 week or more in which a person experiences a change in normal behavior that drastically affects their functioning. Mania can be ... Read the Article 1.25 11 Activity Info
Median Nerve Injury This activity reviews the evaluation and treatment of an injury to the median nerve and highlights the role of the healthcare team in managing patien ... Read the Article 1.75 22 Activity Info
Mediastinoscopy Mediastinoscopy is a thoracic surgical procedure performed with a mediastinoscope to examine the mediastinum— the space in the thoracic cavity between ... Read the Article 1 5 Activity Info
Megaloblastic Anemia Megaloblastic anemia (MA) encompasses a heterogeneous group of anemias characterized by the presence of large red blood cell precursors called megalob ... Read the Article 1 6 Activity Info
Metabolic Syndrome Metabolic syndrome is an accumulation of several disorders, which together raise the risk of an individual developing atherosclerotic cardiovascular d ... Read the Article 1 7 Activity Info
Methemoglobinemia Methemoglobinemia is a condition with life-threatening potential in which diminution of the oxygen-carrying capacity of circulating hemoglobin occurs ... Read the Article 1 6 Activity Info
Middle Cerebral Artery Stroke The middle cerebral artery (MCA) is the most common artery involved in acute stroke. It branches directly from the internal carotid artery and consist ... Read the Article 1.25 11 Activity Info
Multiple Endocrine Neoplasias Type 2 Multiple endocrine neoplasia type 2 (MEN 2) is a hereditary cancer syndrome associated primarily with tumors of the adrenal gland, thyroid and parathy ... Read the Article 1.25 10 Activity Info
Myocardial Infarction Myocardial infarction (MI), colloquially known as "heart attack," is caused by decreased or complete cessation of blood flow to a portion of the myoca ... Read the Article 1.25 12 Activity Info
Neisseria Meningitidis Meningococcal infections are an important disease caused by the bacterium, Neisseria meningitidis. It affects people of all ages and can even infect h ... Read the Article 1.25 11 Activity Info
Neonatal Jaundice Neonatal jaundice is yellowish discoloration of the skin, conjunctiva, and sclera due to elevated serum or plasma bilirubin in the newborn period. Neo ... Read the Article 1.25 7 Activity Info
Neuropathy About 2.4 percent of the population is affected by peripheral neuropathy. The prevalence increases to 8 percent in older populations. Peripheral neuro ... Read the Article 1.25 13 Activity Info
Neutropenia Neutrophils play an essential role in immune defenses because they ingest, kill, and digest invading microorganisms, including fungi and bacteria. Fai ... Read the Article 1.25 9 Activity Info
Non ST Segment Elevation Myocardial Infarction Acute coronary syndrome (ACS) can be divided into subgroups of ST-segment elevation myocardial infarction (STEMI), non-ST-segment elevation myocardial ... Read the Article 1 5 Activity Info
Non-Hodgkin Lymphoma Non-Hodgkin lymphoma is a group of malignant neoplasms originating from the lymphoid tissues, mainly the lymph nodes. These tumors may result due to c ... Read the Article 1.5 12 Activity Info
Orbital Cellulitis Orbital cellulitis is defined as a serious infection that involves the muscle and fat located within the orbit. It is also sometimes referred to as po ... Read the Article 1 7 Activity Info
Ovarian Cystadenoma Epithelial neoplasms of the ovary account for 60 percent of all ovarian tumors and 40 percent of benign tumors. They are classified as benign, borderl ... Read the Article 1 4 Activity Info
Overview On Ordering and Evaluation of Laboratory Tests The laboratory medicine service in a hospital is concerned with relevant investigations of patient’s presenting complaints and sometimes with detectio ... Read the Article 2 24 Activity Info
Paget Disease Paget disease is a skeletal growth disorder in which abnormalities such as unusual bone growth can occur in several multifactoral ways. This is often ... Read the Article 1.75 24 Activity Info
Paracoccidioidomycosis Paracoccidioidomycosis (PCM) is a systemic fungal infection caused by a dimorphic fungus endemic in Central and South America. The morbidity and morta ... Read the Article 1 6 Activity Info
Parkinson Disease Parkinson disease is a neurodegenerative disorder that mostly presents in later life with generalized slowing of movements (bradykinesia) and at least ... Read the Article 2 26 Activity Info
Pathophysiology of Obesity Obesity is a chronic disease having a major public health concern. Obesity is a mild state of chronic inflammation of adipose tissue and a state of ma ... Read the Article 1 5 Activity Info
Pediatric Asthma Asthma is a chronic inflammatory disease of the airways, characterized by recurrent episodes of airflow obstruction resulting from edema, bronchospasm ... Read the Article 1.5 18 Activity Info
Pelvic Inflammatory Disease Pelvic inflammatory disease (PID) is defined as an inflammation of the upper genital tract due to an infection in women. The disease affects the uteru ... Read the Article 1.5 19 Activity Info
Periorbital Cellulitis Periorbital cellulitis is sometimes called preseptal cellulitis. It is is a skin and soft tissue infection around the eye that is anterior to the orbi ... Read the Article 1 4 Activity Info
Pituitary Adenoma Pituitary adenomas are tumors of the anterior pituitary. Most pituitary tumors are slow-growing and benign. They are classified based on size or cell ... Read the Article 1.25 10 Activity Info
Plasmacytoma Plasmacytoma is a tumor of plasma cells of bony or soft tissue and can occur anywhere in the body without evidence of systemic disease. It may present ... Read the Article 1.25 7 Activity Info
Pleomorphic Adenoma Pleomorphic adenoma, the most common salivary gland tumor, is also known as benign mixed tumors (BMT's), because of its dual origin from epithelial an ... Read the Article 1.25 9 Activity Info
Pleural Effusion Pleural effusion is the accumulation of fluid in between the parietal and visceral pleura, called the pleural cavity. It can occur by itself or can be ... Read the Article 1.25 8 Activity Info
Pleurisy Pleurisy is a symptom characterized by localized chest pain caused by a disease-causing inflammation of the pleura. Pleurisy can be caused by a primar ... Read the Article 1 6 Activity Info
Polycystic Ovarian Disease Polycystic ovarian syndrome (PCOS) is the most common hormonal disorder in females of reproductive age. It is characterized by two or more of the foll ... Read the Article 1.5 18 Activity Info
Polycythemia Vera Polycythemia vera is a myeloproliferative disorder associated with a Janus kinase-2 (JAK2) mutation that causes the neoplastic proliferation of the he ... Read the Article 1 7 Activity Info
Posterior Cerebral Artery Stroke Posterior cerebral artery (PCA) strokes can be challenging to diagnose, due to the variability in symptoms, which may be nonspecific and inconsistent ... Read the Article 1.25 9 Activity Info
Post-Op Assessment and Management Of Obesity Surgery Obesity surgery is growing in popularity throughout the world. While patient selection is a key factor in determining the success of the surgery, post ... Read the Article 1.25 12 Activity Info
Postoperative Fever Postoperative fever is defined as a temperature higher than 38 C (or greater than 100.4 F) on two consecutive postoperative days or higher than 39 C ( ... Read the Article 1 6 Activity Info
Preeclampsia Preeclampsia is a hypertensive disease that occurs during pregnancy. This disease encompasses 2% to 8% of pregnancy-related complications, greater tha ... Read the Article 1.75 21 Activity Info
Presyncope Presyncope or near-syncope is often ill-defined and may have different meanings to different providers but denotes near fainting or a prodrome of sync ... Read the Article 1 6 Activity Info
Primary Lung Tuberculosis Tuberculosis is the leading cause of death from an infectious agent worldwide, causing even more deaths in HIV/AIDS patients. A third of the world's p ... Read the Article 1.25 11 Activity Info
Prostate Cancer Worldwide, prostate cancer is the most commonly diagnosed malignancy and the sixth leading cause of cancer death in men. In 2012, this amounted to 1,1 ... Read the Article 2.25 25 Activity Info
Pseudoappendicitis Pseudoappendicitis can describe any condition mimicking appendicitis, a disease which classically presents with acute right lower quadrant abdominal p ... Read the Article 1 5 Activity Info
Renal Failure The term renal failure denotes inability of the kidneys to perform excretory function leading to retention of nitrogenous waste products from the bloo ... Read the Article 1 7 Activity Info
Rheumatoid Arthritis Rheumatoid arthritis (RA) is an autoimmune disorder of the joints characterized by inflammatory arthritis as well as extra-articular involvement. It c ... Read the Article 2 24 Activity Info
Rickettsia Rickettsiae Rocky Mountain spotted fever (RMSF) is an acute febrile tick-borne illness caused by Rickettsia rickettsii. In North America, it is both the most seve ... Read the Article 1.25 9 Activity Info
Right Ventricular Myocardial Infarction Myocardial infarction occurs when blood flow to a part of the heart diminishes or stops altogether, causing irreversible damage to the heart muscles. ... Read the Article 1.25 10 Activity Info
Romberg Test This Romberg test illustrates a diagnostic, non-technical, physical test that identifies a specific neurologic impairment. The purpose of this evaluat ... Read the Article 1 3 Activity Info
Root Cause Analysis and Medical Error Prevention Medical error is an unfortunate reality that continues to occur at alarming rates within the United States healthcare system. These mistakes can resul ... Read the Article 1.75 22 Activity Info
Rotor Syndrome Rotor syndrome, also known as Rotor type hyperbilirubinemia, is an autosomal recessive disease and a rare cause of mixed direct (conjugated) and indir ... Read the Article 1 7 Activity Info
Salicylic Acid (Aspirin) Salicylates have been available since the early 1900s. This activity outlines the indications, mechanism of action, methods of administration, importa ... Read the Article 1.75 20 Activity Info
Secondary Thrombocytosis Reactive thrombocytosis, defined as an abnormally high platelet count in the absence of chronic myeloproliferative disease, secondary to an infection, ... Read the Article 1 6 Activity Info
Seizure A seizure represents the uncontrolled, abnormal electrical activity of the brain that may cause changes in the level of consciousness, behavior, memor ... Read the Article 2 26 Activity Info
Seminoma Seminoma is a malignant germ cell tumor that involves most commonly the testicle or less frequently the mediastinum, the retroperitoneum, or other ext ... Read the Article 1.25 8 Activity Info
Sensory Neuropathy Sensory neuropathy is a common condition that is often a direct complication of another comorbidity. It can be debilitating under certain circumstance ... Read the Article 1 3 Activity Info
Shellfish Allergy Shellfish allergies can occur due to immunologic or non-immunological processes, and individuals may react to crustaceans, such as crab or shrimp, or ... Read the Article 1 5 Activity Info
Sickle Cell Anemia Sickle cell anemia is an inherited disorder of the globin chains that causes hemolysis and chronic organ damage. This activity reviews the pathophysio ... Read the Article 2 21 Activity Info
Sleeplessness And Circadian Disorder Proper sleep is vital to maintain health and optimize overall functioning during periods of wakefulness. Sleeplessness has been linked with several he ... Read the Article 1 6 Activity Info
Small Bowel Cancer Small bowel cancer encompasses a series of malignant lesions that may be identified throughout the small intestine (SI). The small bowel lies between ... Read the Article 1 5 Activity Info
Small Bowel Resection This activity will outline the basic steps in a small bowel resection, characterize certain situations requiring resection, and discuss the possible o ... Read the Article 1 5 Activity Info
Solar Urticaria Solar urticaria is a chronic acquired photosensitivity disorder. It consists of recurrent episodes of urticaria overlying areas of the skin that are e ... Read the Article 1 5 Activity Info
Spider Angioma Spider angioma, also known as spider naevus or spider telangiectasia, is a vascular lesion characterized by anomalous dilatation of end vasculature fo ... Read the Article 1 4 Activity Info
Squamous Cell Skin Cancer Squamous cell carcinoma, the second most common form of skin cancer, is caused by the cumulative exposure of skin to UV light. This condition has prec ... Read the Article 1.25 10 Activity Info
Stevens Johnson Syndrome Stevens-Johnson syndrome and toxic epidermal necrolysis are acute, rare, and potentially fatal skin reactions involving loss of skin and, in some case ... Read the Article 1.5 18 Activity Info
Stroke Prevention There is a significant overlap between the risk factors accounting for cardiovascular events and cerebrovascular events. The INTERHEART study looked a ... Read the Article 1 7 Activity Info
Stroke Reperfusion Injury Stroke is a major cause of death and disability worldwide, with a prevalence of about 2.5%. A stroke is called ischemic when caused by an interruption ... Read the Article 1 5 Activity Info
Substance Use Disorder Substance use disorders result from long-term exposure to substances and subsequent mental and physical dependence. This can lead to social, academic, ... Read the Article 1.5 12 Activity Info
Syncope Syncope is a transient loss of consciousness and postural tone followed by spontaneous recovery. While there are numerous classification schemes used ... Read the Article 1.5 14 Activity Info
Testicular Seminoma Testicular seminomas are cancers that can usually be managed with surgical resection, although radiation is added for advanced-stage disease. Stage 1 ... Read the Article 1 5 Activity Info
Testicular Teratoma Testicular teratoma is a neoplasm derived from germ cells of the testicle. It can display diverse biological behavior with an aggressive nature at tim ... Read the Article 1.25 7 Activity Info
Thalassemia Thalassemia is a heterogeneous group of blood disorders affecting the hemoglobin genes and resulting in ineffective erythropoiesis. The decreased prod ... Read the Article 1.25 10 Activity Info
Thoracic Aorta Aneurysm Thoracic aortic aneurysms require a prompt diagnosis as most patients are asymptomatic until dissection or rupture of the aorta occurs, leading to wor ... Read the Article 1.25 9 Activity Info
Thymoma Thymomas and thymic carcinomas originate from the epithelial cells of the thymus within the anterior mediastinum. The presence of histologic heterogen ... Read the Article 1.25 11 Activity Info
Tracheal Cancer Primary tracheal neoplasms are very uncommon but are usually malignant in adults and benign in children. They present with symptoms that mimic other c ... Read the Article 1 4 Activity Info
Trichomoniasis Trichomonas vaginalis is a protozoan responsible for trichomoniasis, one of the most prevalent non-viral sexually transmitted infections (STIs) in the ... Read the Article 1.5 19 Activity Info
Tuberculosis Tuberculosis (TB) is a human disease caused by Mycobacterium tuberculosis. It mainly affects the lungs, making pulmonary disease the most common prese ... Read the Article 2 28 Activity Info
Tuberous Sclerosis Tuberous sclerosis complex (TSC) is a genetic disorder that affects multiple systems. It is inherited in an autosomal dominant fashion and is characte ... Read the Article 2.25 32 Activity Info
Type IV Hypersensitivity Reaction Type four hypersensitivity reaction is a cell-mediated reaction that can occur in response to contact with certain allergens resulting in what is call ... Read the Article 1 7 Activity Info
Ulcerative Colitis Ulcerative colitis is an idiopathic inflammatory condition of the colon which results in diffuse friability and superficial erosions on the colonic wa ... Read the Article 2 26 Activity Info
Upper Limb Amputation Upper extremity amputations are a procedure commonly done in a variety of circumstances including infection, trauma, cancer, disease progression or co ... Read the Article 1.25 6 Activity Info
Uterine Leiomyomata Uterine leiomyomata or fibroids are an extremely common benign neoplasm in women of reproductive age. Although they are benign, they can have a signif ... Read the Article 1.5 18 Activity Info
Uveitis Uveitis is a disease process that involves inflammation of the eye. There are multiple different causes of uveitis. These include infections, inflamma ... Read the Article 1.5 16 Activity Info
Varicella Zoster Chickenpox or varicella is a contagious disease caused by the varicella-zoster virus (VZV). The virus is responsible for chickenpox (usually primary i ... Read the Article 2 27 Activity Info
Vertebrobasilar Stroke Vertebrobasilar strokes are interruptions of blood flow to the posterior circulation. While these types of strokes are relatively uncommon, they are a ... Read the Article 1 5 Activity Info
Vitamin A Vitamin A is a general term encompassing various fat-soluble substances such as retinol, retinyl palmitate, and beta-carotene. Its various metabolites ... Read the Article 1 7 Activity Info
Vitamin D Vitamin D is labeled as the "sunshine vitamin," as it is produced in the skin on sun exposure. Vitamin D is required to maintain serum calcium concent ... Read the Article 1 7 Activity Info
Vitiligo Vitiligo is a common acquired skin disorder which results from the loss of melanocytes from the epidermis and clinically manifests as well-demarcated ... Read the Article 1.25 8 Activity Info
Vulva Cancer Vulvar cancer represents 0.3% of all new cancer cases in the United States. Squamous cell carcinoma is the most common type and is usually diagnosed a ... Read the Article 1.25 11 Activity Info
Warthin Tumor Warthin tumor is a relatively frequent and benign neoplasm of the major salivary glands. It is histologically characterized by a dense lymphoid stroma ... Read the Article 1.25 8 Activity Info
Wernicke Encephalopathy Wernicke encephalopathy is an acute neurological condition characterized by a clinical triad of ophthalmoplegia, ataxia, and confusion. This disease i ... Read the Article 1.25 11 Activity Info
Wilson Disease Wilson disease (hepatolenticular degeneration) is a rare, autosomal recessive disorder caused by abnormal copper accumulation in the body particularly ... Read the Article 2 30 Activity Info
Zenker Diverticulum Zenker diverticulum develops in the hypopharynx, typically between the cricopharyngeus muscle and the inferior pharyngeal constrictor muscle at the le ... Read the Article 1.25 13 Activity Info
Zika Virus Zika virus is a single-stranded RNA virus of the family and the genus Flavivirus. In the majority of people, infection by the Zika virus is mild and s ... Read the Article 1.25 10 Activity Info
Zinc Zinc is a medication used in the management and treatment of diarrhea. It is in the mineral and supplemental class of drugs. This activity outlines th ... Read the Article 1 5 Activity Info
Zollinger Ellison Syndrome Zollinger-Ellison syndrome could impact the patient's quality of life and increase mortality if it is not recognized and treated. This activity covers ... Read the Article 1.5 14 Activity Info

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