High Anion Gap Metabolic Acidosis

Overview

4.6 out of 5 (17 Reviews)

Credits

1.00

Pharmacology Credits

0.5

Post Assessment Questions

5

Start Date

1 Sep 2023

Last Review Date

1 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


 
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Activity Description

High anion gap metabolic acidosis (HAGMA) is a type of metabolic acidosis. Differentiation of acidosis into a particular subtype, whether high anion gap metabolic acidosis or non-anion gap metabolic acidosis aids in the determination of the etiology and hence appropriate treatment. First, to determine whether there is a high anion gap, the anion gap must be calculated. However, in patients with abnormal levels of albumin this must be corrected. If the corrected anion gap is greater than 12, this suggests an increased presence of unmeasured anions. Subsequently, the osmolar gap should be calculated to screen for the presence of alcohols, and ethanol, acetaminophen, lactate, salicylic acid, creatinine, and ketones should be measured. Additional testing includes arterial or venous blood gas, urinalysis, complete blood count, and evaluation of concomitant respiratory or metabolic disturbances. Calculating the delta/delta ratio of anion gap and bicarbonate can aid in this. Checking for D-lactate would be appropriate in a patient with short gut syndrome (post gastric-bypass surgery), as delivery of a large amount of carbohydrate to the colon could promote bacterial secretion of said chemical not typically tested for. EKG could detect changes caused by abnormal electrolytes, and abdominal radiography could be employed to evaluate for renal stones or iron ingestion. This activity describes the pathophysiology, evaluation, and management of high anion gap metabolic acidosis and highlights the role of the interprofessional team in enhancing care delivery for affected patients.

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Describe the causes of high anion gap metabolic acidosis.
  • Summarize the treatment options for high anion gap metabolic acidosis.
  • Explain the pathophysiology of high anion gap metabolic acidosis.
  • Explain the importance of enhancing coordination amongst interprofessional team members to improve outcomes for patients with high anion gap metabolic acidosis.
  • Outline the pharmacologic therapy as it applies to High Anion Gap Metabolic Acidosis

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurse Practitioners: StatPearls designates this activity for 1.00 ANCC contact hour(s), which includes 0.5 hour(s) of pharmacology. NPs should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Mrs W. on 8/2/2021

sharon s. on 11/6/2021

Gibi G. on 11/22/2021

susma r. on 12/4/2021

Whitney C. on 4/24/2022

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