Chronic Kidney Transplant Rejection

Chronic Kidney Transplant Rejection

Credits: 1.00   Post-Assessment Questions:  5

Release Date: 5 Oct 2020
Expiration Date: 10 Jul 2021
Last Reviewed: 10 Jul 2020
Estimated Time To Finish: 60 Minutes

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Activity Description

Kidney transplantation is currently the definitive treatment for patients with end-stage kidney disease (ESKD). Compared to dialysis, kidney transplantation is associated with reduced mortality and improved quality of life. Rejection of the kidney is one of the leading causes of allograft loss. This activity reviews the epidemiology, etiology, classification, diagnosis, and management of chronic kidney transplant rejection. It specifically focuses on the immune mechanisms of chronic kidney transplant rejection, the characteristic histopathological lesions of immune-mediated chronic rejection, how to differentiate chronic rejection from other causes of renal allograft dysfunction, and how to effectively diagnose and manage patients with chronic rejection.

Target Audience

This activity has been designed to meet the educational needs of nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

• Identify the etiology and classification of chronic kidney transplant rejection.
• Describe the characteristic histopathological lesions of chronic active antibody-mediated and t cell-mediated rejection.
• Review the current diagnostic approach to a patient with suspected chronic kidney transplant rejection, which starts with detailed history taking, ordering the appropriate laboratory and imaging tests, and the timely referral for biopsy.

Author(s) / Contributors Disclosure of Conflicts of Interest

Each author, editor, faculty and planning committee member have completed a disclosure form indicating that neither they nor their spouse/partner has a financial interest/arrangement or affiliation that could be perceived as a real or apparent conflict of interest related to the content of this activity.

COMMERCIAL SUPPORT: This activity has received NO commercial support.

Contributors

Hover over the contributor names to see details and disclosures of any financial relationships or relationships they or their spouse/life partner have with commercial interests related to the content of this continuing education activity.

Authors: Mohamed Hassanein
Editors: Joshua Augustine
Editors-In-Chief: Scott KinkadeMaximos AttiaTracey Davidoff
Chief Medical Reviewer: Muhammad Hashmi
Nurse Planner/Reviewer/Editor: Lisa Haddad
Nurse Planner/Reviewer/Editor: Bernadette Makar
Nurse Planner/Reviewer/Editor: Dorothy Caputo
Pharmacy Planner/Reviewer/Editor: Mark Pellegrini
Physician Planner/Reviewer/Editor: Scott Dulebohn

Continuing Education Accreditation Information

This activity has been planned and implemented in accordance with the Accreditation Standards of the American Association of Nurse Practitioners (AANP) through the joint providership of AKH Inc., Advancing Knowledge in Healthcare and StatPearls Publishing, LLC.  AKH Inc., Advancing Knowledge in Healthcare is accredited by the American Association of Nurse Practitioners as an approved provider of nurse practitioner continuing education. Provider number: 030803.  This activity is approved for 1.00 contact hour(s) (which includes 0.1 hour(s) of pharmacology).

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• StatPearls and AKH reserve the right to cancel any course due to unforeseen circumstances. StatPearls and AKH will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

• StatPearls and AKH are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

• Computer Requirements:  Internet Access
• E-mail Address

Instructions for Credit

1. Register for the activity and create a StatPearls login.     
2. Review the required accreditation information:  Target audience, learning objectives, and disclosure information.
3. Complete the entire self-study activity.
4. Complete the post-test assessments.
5. Successfully pass the post-test with a minimum score of 100%.
6. Complete the evaluation form.
7. Obtain a certificate.

StatPearls and AKH adhere to provider standards regarding commercial support of continuing education. It is the policy of StatPearls and AKH that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

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Media Usage Rights

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