Losartan

Overview

4.6 out of 5 (33 Reviews)

Credits

1.00

Pharmacology Credits

1.00

Post Assessment Questions

7

Start Date

1 Sep 2023

Last Review Date

26 Feb 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


 
Need Help?  If you have a system or content concerns, please contact support@statpearls.com

Activity Description

Losartan is an angiotensin receptor blocker (ARB) approved by the US Food and Drug Administration (FDA) for the treatment of several medical conditions, including hypertension and diabetic nephropathy. Losartan inhibits angiotensin II–induced vasopressin release, adrenal catecholamine release, rapid and slow pressor responses, thirst, cellular hypertrophy and hyperplasia, noradrenergic neurotransmission, and sympathetic tone increase. 

In addition, losartan inhibits angiotensin II–induced vasoconstriction and the effects of aldosterone, thereby lowering blood pressure. ARBs exhibit renoprotective effects in type 2 diabetes. In hypertension with left ventricular hypertrophy, losartan inhibits angiotensin II-induced cardiac remodeling, consequently reducing the risk of stroke in these patients. This activity reviews the use of losartan, including indications, mechanism of action, contraindications, pharmacokinetics, adverse event profiles, eligible patient populations, and monitoring. This activity also highlights the critical role of the interprofessional healthcare team in managing hypertension and diabetic nephropathy with losartan.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify appropriate indications for losartan therapy, including hypertension and diabetic nephropathy, based on patient-specific clinical presentations and guidelines.

  • Implement appropriate dosing strategies for losartan based on patient-specific factors, such as renal function and comorbidities.

  • Apply knowledge of potential adverse effects of losartan, including hyperkalemia and angioedema, to promptly recognize and manage adverse reactions.

  • Collaborate with other healthcare team members to ensure comprehensive care for patients prescribed losartan when managing complex cases involving losartan therapy to optimize patient outcomes.

  • Outline the indications of Losartan

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurse Practitioners: StatPearls designates this activity for 1.00 ANCC contact hour(s), which includes 1.00 hour(s) of pharmacology. NPs should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Deborah Z. on 3/29/2021

John L. on 10/3/2021

Candace H. on 2/7/2022

Rebecca I. on 5/11/2022

Natalia M. on 8/21/2022

Nicole G. on 8/28/2022

Sharon H. on 9/3/2022

IRIS O. on 9/30/2022

Toni-Marie P. on 10/21/2022

MEGAN T. on 10/24/2022

mandeep s. on 11/5/2022

susan m. on 11/9/2022

none

shawna v. on 12/20/2022

Li Mei L. on 12/30/2022

jubril o. on 1/21/2023

Shanae M. on 2/12/2023

Dominika S. on 2/13/2023

Leland J. on 2/13/2023

amy s. on 2/16/2023

Elizabeth H. on 2/27/2023

leiling c. on 3/22/2023

Tammy S. on 3/28/2023

Steven H. on 4/16/2023

Jenna M. on 5/1/2023

Kim L. on 5/3/2023

Arelly J. on 6/1/2023

Ann F. on 7/23/2023

Kathleen on 9/2/2023

VLADIMIR E. on 9/5/2023

Kelsey G. on 10/18/2023

Bennal P. on 1/23/2024

Puneet T. on 2/21/2024

Samuel O. on 3/12/2024

Unlimited Nurse Practitioner CE

Stay up to date on the latest medical knowledge with 6675 CE activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 7930 hours of CE.

Single Activity

Take this single activity

$49 1 activity

6 Month Unlimited Nurse Practitioner CE

Access to all the Unlimited Nurse Practitioner CE activities in all specialties.

$379 per half year per user

1 Year Unlimited Nurse Practitioner CE

Access to all the Unlimited Nurse Practitioner CE activities in all specialties.

$579 per 1 year per user