Cyanocobalamin

Overview

5 out of 5 (12 Reviews)

Credits

1.00

Post Assessment Questions

6

Start Date

1 Sep 2023

Last Review Date

31 Jan 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


 
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Activity Description

Cyanocobalamin is a synthetic compound of vitamin B12 used to treat vitamin deficiencies. Chemically, cyanocobalamin is classified as a "corrinoid," representing a crystallizable cobalt complex. The name "cyanocobalamin" is derived from including a cyanide group within the molecule. Cyanocobalamin is approved by the United States Food and Drug Administration (FDA) for pernicious anemia, malabsorption, atrophic gastritis, gastrectomy, Helicobacter pylori infection, and other conditions.

Vitamin B12 facilitates several methylation reactions within the body. Methylcobalamin serves as a cofactor in the conversion of homocysteine to methionine in the body. Furthermore, in the form of adenosylcobalamin, the vitamin is crucial in converting methylmalonyl-coenzyme A (CoA) to succinyl-CoA. Both of these reactions are essential for cell division and growth. This activity provides a comprehensive review of cyanocobalamin, covering the indications, mechanism of action, adverse event profile, contraindications, and relevant interactions, as a valuable agent managing vitamin B12 deficiencies. This review is particularly relevant for interprofessional healthcare teams who care for patients with indicated conditions to enhance long-term outcomes.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify patients with vitamin B12 deficiencies who may benefit from cyanocobalamin therapy based on clinical presentations, medical history, and diagnostic findings.

  • Implement evidence-based guidelines into clinical practice to effectively prescribe and administer cyanocobalamin for different vitamin B12 deficiency disorders, considering optimal routes of administration.

  • Select appropriate cyanocobalamin formulations and dosages based on patient characteristics, response to therapy, and the specific indications for vitamin B12 supplementation.

  • Collaborate with other healthcare professionals to ensure a multidisciplinary approach in managing complex cases of vitamin B12 deficiencies, incorporating diverse perspectives for comprehensive care.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurses: StatPearls designates this activity for 1.00 ANCC contact hour(s). Nurses should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Sarah B. on 12/1/2021

Aimee S. on 7/17/2022

Robert T. on 7/30/2022

Mark O. on 10/28/2022

jeffrey t. on 12/6/2022

Karl S. on 1/12/2023

Shuhao Q. on 4/19/2023

Dr Sruthi G. on 6/11/2023

Amy G. on 8/2/2023

Aparna C. on 12/27/2023

Swaminathan I. on 1/12/2024

Peter S. on 2/13/2024

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