Clonidine Toxicity

Overview

4.3 out of 5 (15 Reviews)

Credits

1.00

Post Assessment Questions

4

Start Date

1 Sep 2023

Last Review Date

1 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


 
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Activity Description

Clonidine is a commonly prescribed biochemical derivative of imidazoline with a variety of clinical uses. It was originally developed as a nasal decongestant, but its main use has been an anti-hypertensive agent. In recent years it has gained popularity in pediatric patients for the treatment of attention-deficit hyperactivity disorder (ADHD), Tourette syndrome, and sleep disturbances. It has also been shown to be useful in treating several different drug withdrawal syndromes. Clonidine’s effect on the body stems from its action on alpha-2 receptors, imidazoline receptors, and the functional overlap of alpha-2 receptors on mu receptors. Overdose results in a toxidrome not easily identified. This activity reviews the etiology, presentation, evaluation, and management/prevention of clonidine toxicity and reviews the role of the interprofessional team in evaluating, diagnosing, and managing the condition.

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Describe the basic pathophysiology/toxicokinetics of clonidine toxicity.
  • Summarize some of the various presenting signs and symptoms that would accompany clonidine toxicity.
  • Review treatment and management strategies available for clonidine toxicity.
  • Evaluate possible interprofessional team strategies for improving care coordination and communication to advance the evaluation and treatment of clonidine toxicity and improve outcomes.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurses: StatPearls designates this activity for 1.00 ANCC contact hour(s). Nurses should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Missy H. on 1/23/2022

Kathleen H. on 3/16/2022

Henry H. on 7/13/2022

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Adithya nikhileshwar B. on 8/1/2023

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Suman S. on 3/3/2024

Ehsan Q. on 3/22/2024

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